LA JOLLA—Father of genetics Gregor Mendel spent years tediously observing and measuring pea plant traits by hand in the 1800s to uncover the basics of genetic inheritance. Today, botanists can track the traits, or phenotypes, of hundreds or thousands of plants much more quickly, with automated camera systems. Now, Salk researchers have helped speed up plant phenotyping even more, with machine-learning algorithms that teach a computer system to analyze three-dimensional shapes of the branches and leaves of a plant. The study, published in Plant Physiology on October 7, 2019, may help scientists better quantify how plants respond to climate change, genetic mutations or other factors.
LA JOLLA—Plants can do many amazing things. Among their talents, they can manufacture compounds that help them repel pests, attract pollinators, cure infections and protect themselves from excess temperatures, drought and other hazards in the environment.
LA JOLLA—Iron is essential for plant growth, but with heavy rainfall and poor aeration, many acidic soils become toxic with excess iron. In countries with dramatic flood seasons, such as in West Africa and tropical Asia, toxic iron levels can have dire consequences on the availability of staple foods, such as rice.
LA JOLLA—Hidden underground networks of plant roots snake through the earth foraging for nutrients and water, similar to a worm searching for food. Yet, the genetic and molecular mechanisms that govern which parts of the soil roots explore remain largely unknown. Now, Salk Institute researchers have discovered a gene that determines whether roots grow deep or shallow in the soil.
LA JOLLA—What will a three-degree-warmer world look like? How will plants fare in more extreme weather conditions? When experiencing stress or damage from various sources, plants use chloroplast-to-nucleus communication to regulate gene expression and help them cope.
LA JOLLA—The Salk Institute’s Harnessing Plants Initiative to combat climate change using plants, led by Professor Joanne Chory, executive director of the Harnessing Plants Initiative, will receive funding of more than $35 million from over 10 individuals and organizations through The Audacious Project, a highly competitive program housed at TED, the nonprofit devoted to ideas worth spreading. The collective commitments represent one of the largest gifts to a single project in the Institute’s history.
LA JOLLA—Salk researchers have mapped the genomes and epigenomes of genetically modified plant lines with the highest resolution ever to reveal exactly what happens at a molecular level when a piece of foreign DNA is inserted. Their findings, published in the journal PLOS Genetics on January 18, 2019, elucidate the routine methods used to modify plants, and offer new ways to more effectively minimize potential off-target effects.
LA JOLLA—When a building is damaged, a general contractor often oversees various subcontractors—framers, electricians, plumbers and drywall hangers—to ensure repairs are done in the correct order and on time.
LA JOLLA—Salk Institute and Purdue University scientists have discovered the switch in plants that turns off production of terpenoids—carbon-rich compounds that play roles in plant physiology and are used by humans in everything from fragrances and flavorings to biofuels and pharmaceuticals.
LA JOLLA—Not all of your genome needs to be active at any given time. Some regions are prone to hopping around the genome in problematic ways if left unchecked; others code for genes that need to be turned off in certain cells or at certain times. One way that cells keep these genetic elements under control is with the chemical equivalent of a “do not use” sign. This chemical signal, called DNA methylation, is known to vary in different cell types or at different stages of cellular development, but the details of how cells regulate exactly where to put DNA methylation marks have remained unclear.
LA JOLLA—When you see brown spots on otherwise healthy green leaves, you may be witnessing a plant’s immune response as it tries to keep a bacterial infection from spreading. Some plants are more resistant to such infections than others, and plant biologists want to understand why. Salk Institute scientists studying a plant protein called SOBER1 recently discovered one mechanism by which, counterintuitively, plants seem to render themselves less resistant to infection.
LA JOLLA—Salk Institute Professors Joanne Chory and Terrence Sejnowski have been elected Fellows of the National Academy of Inventors (NAI). Chory is director of the Salk Institute’s Plant Molecular and Cellular Biology Laboratory, a Howard Hughes Medical Institute (HHMI) Investigator and holder of the Howard H. and Maryam R. Newman Chair in Plant Biology. Sejnowski is head of the Institute’s Computational Neurobiology Laboratory, an HHMI Investigator and holder of the Francis Crick Chair.
La Jolla—Salk Institute scientist Joanne Chory, one of the world’s preeminent plant biologists who is now leading the charge to combat global warming with plant-based solutions, has been awarded a 2018 Breakthrough Prize for her pioneering work deciphering how plants optimize their growth, development and cellular structure to transform sunlight into chemical energy.
LA JOLLA—Plants and brains are more alike than you might think: Salk scientists discovered that the mathematical rules governing how plants grow are similar to how brain cells sprout connections. The new work, published in Current Biology on July 6, 2017, and based on data from 3D laser scanning of plants, suggests there may be universal rules of logic governing branching growth across many biological systems.
LA JOLLA—Salk scientists have developed a new high-throughput technique to determine which proteins in a cell interact with each other. Mapping this network of interactions, or “interactome,” has been slow going in the past because the number of interactions that could be tested at once was limited. The new approach, published June 26 in Nature Methods, lets researchers test millions of relationships between thousands of proteins in a single experiment.
LA JOLLA—(June 1, 2017) Once we start coloring our hair, we may be surprised to learn that we begin to have a problem in common with plant biologists: finding the right dye for our roots. In the case of the biologists, just the right chemical is needed to measure exactly how plant roots grow. Now, a researcher at the Salk Institute has discovered a fluorescent dye that, paired with other imaging techniques, reveals root growth to be influenced by a major plant hormone more than previously thought.
LA JOLLA—Just like people, plants need iron to grow and stay healthy. But some plants are better at getting this essential nutrient from the soil than others. Now, a study led by a researcher at the Salk Institute has found that variants of a single gene can largely determine a plant’s ability to thrive in environments where iron is scarce.
LA JOLLA—We can tell when plants need water: their leaves droop and they start to look dry. But what’s happening on a molecular level?
LA JOLLA—A new technique developed by Salk Institute scientists for rapidly mapping regions of DNA targeted by regulatory proteins could give scientists insight into what makes some plants drought tolerant or disease resistant, among other traits.
LA JOLLA—Agricultural grafting dates back nearly 3,000 years. By trial and error, people from ancient China to ancient Greece realized that joining a cut branch from one plant onto the stalk of another could improve the quality of crops.
LA JOLLA—Despite seeming passive, plants wage wars with each other to outgrow and absorb sunlight. If a plant is shaded by another, it becomes cut off from essential sunlight it needs to survive.
LA JOLLA–As food demands rise to unprecedented levels, farmers are in a race against time to grow plants that can withstand environmental challenges–infestation, climate change and more. Now, new research at the Salk Institute, published in Science on October 23, 2015, reveals details into a fundamental mechanism of how plants manage their energy intake, which could potentially be harnessed to improve yield.
LA JOLLA—Salk Institute plant biologist Julie Law has been named a Rita Allen Foundation Scholar, a distinction given to biomedical scientists whose research holds exceptional promise for advancing the frontiers of knowledge about how biological systems function in health and disease.
Salk scientist Joanne Chory, a professor in the Plant Molecular and Cellular Biology Laboratory, has received the prestigious honor of being elected to the American Philosophical Society (APS). The APS is an eminent scholarly organization of international reputation, which promotes useful knowledge in the sciences and humanities. This country’s first learned society, the APS has played an important role in American cultural and intellectual life for over 250 years.
LA JOLLA–Salk Institute Professors Joseph Ecker and Dennis O’Leary have received the prestigious honor of being elected to the American Academy of Arts and Sciences (AAAS) class of 2015. One of the nation’s most prominent honorary societies, AAAS are among the 197 accomplished leaders from academia, business, public affairs, the humanities and the arts accepted to this year’s class. Its members include winners of the Nobel Prize and Pulitzer Prize; MacArthur and Guggenheim Fellowships; and Grammy, Emmy, Oscar and Tony Awards.
LA JOLLA—For hundreds of years, healers in São Tomé e Príncipe—an island off the western coast of Africa—have prescribed cata-manginga leaves and bark to their patients. These pickings from the Voacanga africana tree are said to decrease inflammation and ease the symptoms of mental disorders.
LA JOLLA—A chemical that’s found in fruits and vegetables from strawberries to cucumbers appears to stop memory loss that accompanies Alzheimer’s disease in mice, scientists at the Salk Institute for Biological Studies have discovered. In experiments on mice that normally develop Alzheimer’s symptoms less than a year after birth, a daily dose of the compound—a flavonol called fisetin—prevented the progressive memory and learning impairments. The drug, however, did not alter the formation of amyloid plaques in the brain, accumulations of proteins which are commonly blamed for Alzheimer’s disease. The new finding suggests a way to treat Alzheimer’s symptoms independently of targeting amyloid plaques.
LA JOLLA, CA—It’s common wisdom that one rotten apple in a barrel spoils all the other apples, and that an apple ripens a green banana if they are put together in a paper bag. Ways to ripen, or spoil, fruit have been known for thousands of years-as the Bible can attest-but now the genes underlying these phenomena of nature have been revealed.
LA JOLLA, CA—In the spring following a forest fire, trees that survived the blaze explode in new growth and plants sprout in abundance from the scorched earth. For centuries, it was a mystery how seeds, some long dormant in the soil, knew to push through the ashes to regenerate the burned forest.
LA JOLLA, CA—Scientists at the Salk Institute for Biological Studies have identified patterns of epigenomic diversity that not only allow plants to adapt to various environments, but could also benefit crop production and the study of human diseases.
LA JOLLA, CA—You might think you have nothing in common with mustard except hotdogs. Yet based on research in a plant from the mustard family, Salk scientists have discovered a possible explanation for how organisms, including humans, directly regulate chemical reactions that quickly adjust the growth of organs. These findings overturn conventional views of how different body parts coordinate their growth, shedding light on the development of more productive plants and new therapies for metabolic diseases.
LA JOLLA,CA—Salk faculty members Joseph Ecker and Joseph Noel have been named as 2012 Fellows by the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and the publisher of the journal Science. Election as an AAAS Fellow is among the highest honors in American science and scholars are selected by their peers for “scientifically or socially distinguished efforts to advance science or its applications,” according to election administrators.
LA JOLLA,CA—The Salk Institute announced today that professors Edward M. Callaway and Joseph Noel have been appointed to endowed chairs in acknowledgment of their outstanding contributions and dedication to scientific research.
LA JOLLA, CA—Scientists at the Salk Institute for Biological Studies have discovered a key genetic switch by which plants control their response to ethylene gas, a natural plant hormone best known for its ability to ripen fruit, but which, under stress conditions, can cause wilted leaves, premature aging and spoilage from over-ripening. The findings, published August 30 in Science magazine, may hold the key to manipulating plants’ ethylene on/off switch, allowing them to balance between drought resistance and growth and, therefore, decrease crop losses from drought conditions.
LA JOLLA, CA—It was long thought that methylation, a crucial part of normal organism development, was a static modification of DNA that could not be altered by environmental conditions. New findings by researchers at the Salk Institute for Biological Studies, however, suggest that the DNA of organisms exposed to stress undergo changes in DNA methylation patterns that alter how genes are regulated.
LA JOLLA, CA—Scientists at the Salk Institute for Biological Studies and Iowa State University discovered a family of plant proteins that play a role in the production of seed oils, substances important for animal and human nutrition, biorenewable chemicals and biofuels.
LA JOLLA, CA—Mild mannered though they seem, plants are extremely competitive, especially when it comes to getting their fair share of sunlight. Whether a forest or a farm, where plants grow a battle rages for the sun’s rays.
LA JOLLA, CA—The Genetics Society of America(GSA) has honored Joanne Chory, Salk Institute professor and director of the Plant Molecular and Cellular Biology Laboratory and Howard H. and Maryam R. Newman Chair in Plant Biology, as the recipient of the prestigious 2012 Genetics Society of America Medal.
LA JOLLA, CA—The Salk Institute is pleased to announce the appointment of five faculty members to be recipients of endowed chairs established by philanthropic leaders in support of scientific research.