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Salk News


Scientists create first map of DNA modification in the developing human brain

LA JOLLA—A new study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin—DNA and proteins—plays a critical role. This work offers new insights into how early brain development shapes lifelong mental health.


Salk Institute’s Nicola Allen receives 2024 NIH Director’s Pioneer Award

LA JOLLA—The National Institutes of Health (NIH) has selected Salk Associate Professor Nicola Allen to receive a 2024 NIH Director’s Pioneer Award. The award recognizes exceptionally creative scientists pursuing highly innovative research and groundbreaking approaches to major challenges in biomedical, behavioral, or social sciences.


New brain-mapping tool may be the “START” of next-generation therapeutics

LA JOLLA—Scientists at the Salk Institute are unveiling a new brain-mapping neurotechnology called Single Transcriptome Assisted Rabies Tracing (START). The cutting-edge tool combines two advanced technologies—monosynaptic rabies virus tracing and single-cell transcriptomics—to map the brain’s intricate neuronal connections with unparalleled precision.


One in three Americans has a dysfunctional metabolism, but intermittent fasting could help

LA JOLLA—More than one-third of adults in the United States have metabolic syndrome, a cluster of conditions that significantly raise a person’s risk of heart disease, stroke, and type 2 diabetes. These conditions include high blood pressure, elevated blood sugar, excess abdominal fat, and abnormal cholesterol levels.


Fuel level low! Energy deficits harm athletes’ health, new research tool reveals how

LA JOLLA—In 2014, the International Olympic Committee named a syndrome affecting many of its athletes: relative energy deficiency in sport, or REDs. It’s now estimated that more than 40% of professional athletes have REDs, and the rate could be even higher in recreational athletes and exercisers.


Salk Science Network enables trailblazing research collaborations with swift data transfers

LA JOLLA—The Salk Institute has launched the Salk Science Network (SciNET), a new state-of-the-art, high-speed network that enhances scientific data transfer between research collaborators. This offering is the latest advancement enabled by Salk’s Biocomputation Initiative, which aims to provide the funding, technology, and expertise required to address the challenges posed by increasingly data-intensive research in biological sciences, such as machine learning and artificial intelligence.


Science and art converged at the 28th annual Symphony at Salk

LA JOLLA—The 28th annual Symphony at Salk welcomed more than 400 attendees to the Salk Institute’s iconic Courtyard on August 17. The concert under the stars showcased an outstanding performance by the San Diego Symphony Orchestra, conducted by Sean O’Loughlin and presented by Zenith-level sponsors Ann Tsukamoto-Weissman and Irv Weissman, and featured guest artists David Foster, sixteen-time Grammy Award®-winning musician, composer, and producer, and Katharine McPhee, acclaimed singer and television/Broadway star, and special guest Daniel Emmet, an outstanding, multi-lingual young vocalist.


Salk Professor Rusty Gage awarded 2024 Taylor International Prize in Medicine

LA JOLLA—Professor Rusty Gage has been awarded the 2024 J. Allyn Taylor International Prize in Medicine by the Schulich School of Medicine & Dentistry and the Robarts Research Institute at Western University. One of the most prestigious medical research awards in Canada, the Taylor Prize recognizes scientists for transformative, career-defining work in basic sciences, translational research, and medical innovations.


Salk Institute mourns the loss of Rebecca Newman, former vice president

LA JOLLA—The Salk Institute mourns the loss of Rebecca Newman, who served as the Institute’s vice president of External Relations from 2008 to 2022. She died on August 3, 2024.


Salk awarded $3.6 million by the California Institute for Regenerative Medicine to advance research on brain aging

LA JOLLA—The Salk Institute was awarded $3.6 million by the California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine. Salk Professor Rusty Gage will lead the new CIRM-funded Shared Resources Laboratory focused on stem cell-based models of aging and neurodegeneration.


Salk Professor Janelle Ayres named Howard Hughes Medical Institute Investigator

LA JOLLA—Salk Professor Janelle Ayres has been selected as a 2024 Howard Hughes Medical Institute (HHMI) Investigator. The HHMI Investigators program awards established scientists with approximately $9 million in funding over seven years to pursue boundary-breaking research in their field. The honor recognizes her influential work in immunology and microbiology and its applications to the global crisis of antibiotic resistance.


New tools reveal neuropeptides, not fast neurotransmitters, encode danger in the brain

LA JOLLA—In the split second as you accidentally touch the hot handle of a cast iron skillet, pain and a sense of danger rush in. Sensory signals travel from the pain receptors in your finger, up through your spinal cord, and into your brainstem. Once there, a special group of neurons relays those pain signals to a higher brain area called the amygdala, where they trigger your emotional fear response and help you remember to avoid hot skillets in the future.


Study reveals key gene protecting plants from harmful metals in soil

LA JOLLA—The negative impact of human activity on Earth doesn’t just affect our planet’s atmosphere—it goes much deeper, into its soils. For instance, excessive application of manure or sewage sludge can increase heavy metal concentrations in agricultural land where vital crops are grown. One of these heavy metals is zinc, a micronutrient necessary for plant and animal health. In excess, however, zinc can be extremely damaging to sensitive plant species.


Salk Professor Joanne Chory named 2024 Wolf Prize Laureate in Agriculture

LA JOLLA—Salk Institute Professor Joanne Chory has been selected by the Wolf Foundation to receive a 2024 Wolf Prize in the field of agriculture for her "key discoveries on plant developmental biology of relevance for crop improvements.” The award is endowed annually to scientists and artists worldwide for their “outstanding achievements in advancing science and the arts for the betterment of humanity.”


28th annual Symphony at Salk to feature David Foster and Katharine McPhee on August 17

LA JOLLA—On Saturday, August 17, the Salk Institute will celebrate 28 years of Symphony at Salk, its premier annual concert under the stars. The unforgettable night will feature a performance by the San Diego Symphony with special guest artists David Foster, 16-time Grammy Award®-winning musician, composer, and producer, and Katharine McPhee, acclaimed singer and television/Broadway star.


Salk Institute launches Neuroimmunology Initiative with $20 million gift from NOMIS Foundation

LA JOLLA—The Salk Institute will receive $20 million over four years from the NOMIS Foundation to launch a new Neuroimmunology Initiative within the Institute’s NOMIS Center for Immunobiology and Microbial Pathogenesis. By funding research programs, faculty recruitment, and pilot grants, the generous gift will enable Salk scientists to develop a deep understanding of the crosstalk between the immune and nervous systems and the role it plays in health and disease.


Unveiling Telo-seq: A breakthrough in telomere research on aging and cancer

LA JOLLA—Within each of our cells, long strands of DNA are folded into chromosomes and capped with protective structures called telomeres. But telomeres shorten as we age, eventually getting so whittled down that our chromosomes become exposed, and our cells die. However, the specifics of when and how this shortening occurs and whether certain chromosomes are more affected than others have been unclear—until now.


Salk scientist Jesse Dixon named 2024 Pew Biomedical Scholar

LA JOLLA—Salk Institute Assistant Professor Jesse Dixon has been named a 2024 Pew Biomedical Scholar by The Pew Charitable Trusts. This honor provides funding to early-career investigators who demonstrate outstanding promise in science toward advancing human health. Dixon and the other 21 awardees will each receive $300,000 over four years to support their research.


Salk Institute mourns the loss of John Adler, friend and former trustee

LA JOLLA—The Salk Institute mourns the loss of businessman and philanthropist John Adler, who served on the Institute’s Board of Trustees from 1991 to 2004. He died June 11, 2024, in Greenwich, Connecticut at the age of 96.


2024 Kavli Small Equipment Grant Program Awardees

Congratulations to the awardees of the Kavli Small Equipment Grant Program, where Salk Faculty and Research Professors working in neuroscience, and related fields, submitted proposals to receive funds to purchase or build small equipment needed to further their research.