Juan Carlos Izpisua Belmonte
Professor
Gene Expression Laboratory
Roger Guillemin Chair
Professor
Gene Expression Laboratory
Roger Guillemin Chair
LA JOLLA—Salk scientists have created a new version of the CRISPR/Cas9 genome editing technology that allows them to activate genes without creating breaks in the DNA, potentially circumventing a major …
LA JOLLA—The immune system automatically destroys dysfunctional cells such as cancer cells, but cancerous tumors often survive nonetheless. A new study by Salk scientists shows one method by which fast-growing …
LA JOLLA—Scientists have, for the first time, corrected a disease-causing mutation in early stage human embryos with gene editing. The technique, which uses the CRISPR-Cas9 system, corrected the mutation for …
LA JOLLA—Salk Institute scientists have developed a novel technology to correct disease-causing aberrations in the chemical tags on DNA that affect how genes are expressed. These types of chemical modifications, …
LA JOLLA—Salk scientists and collaborators have shed light on a longstanding question about what leads to variation in stem cells by comparing induced pluripotent stem cells (iPSCs) derived from identical …
LA JOLLA—When scientists talk about laboratory stem cells being totipotent or pluripotent, they mean that the cells have the potential, like an embryo, to develop into any type of tissue …
LA JOLLA—Rapid advances in the ability to grow cells, tissues and organs of one species within an organism of a different species offer an unprecedented opportunity for tackling longstanding scientific …
LA JOLLA—Graying hair, crow’s feet, an injury that’s taking longer to heal than when we were 20—faced with the unmistakable signs of aging, most of us have had a least …
LA JOLLA—Salk Institute researchers have discovered a holy grail of gene editing—the ability to, for the first time, insert DNA at a target location into the non-dividing cells that make …
LA JOLLA—Salk Professor Juan Carlos Izpisua Belmonte has been awarded a 2016 National Institutes of Health Pioneer Award, a highly coveted grant that supports the most innovative biomedical research, for …
Click …
LA JOLLA–Healthy brain, muscle, eye and heart cells would improve the lives of tens of thousands of people around the world with debilitating mitochondrial diseases. Now, researchers at the Salk …
LA JOLLA–Scientists at the Salk Institute have discovered a novel type of pluripotent stem cell–cells capable of developing into any type of tissue–whose identity is tied to their location in …
LA JOLLA–A study tying the aging process to the deterioration of tightly packaged bundles of cellular DNA could lead to methods of preventing and treating age-related diseases such as cancer, …
LA JOLLA–For thousands of women around the globe carrying a mitochondrial disease, having a healthy child can be a gamble. This set of diseases affect mitochondria, tiny powerhouses that generate …
LA JOLLA–Imagine a single drug that could prevent human immunodeficiency virus (HIV) infection, treat patients who have already contracted HIV, and even remove all the dormant copies of the virus …
LA JOLLA–Researchers at the Salk Institute have healed injured hearts of living mice by reactivating long dormant molecular machinery found in the animals’ cells, a finding that could help pave …
LA JOLLA—For the first time, scientists have turned human skin cells into transplantable white blood cells, soldiers of the immune system that fight infections and invaders. The work, done at …
LA JOLLA—The ability to switch out one gene for another in a line of living stem cells has only crossed from science fiction to reality within this decade. As with …
LA JOLLA, CA—Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for …
LA JOLLA, CA—Stem cells are key to the promise of regenerative medicine: the repair or replacement of injured tissues with custom grown substitutes. Essential to this process are induced pluripotent …
LA JOLLA, CA—A new method for generating stem cells from mature cells promises to boost stem cell production in the laboratory, helping to remove a barrier to regenerative medicine therapies …
LA JOLLA, CA—For more than 20 years, doctors have been using cells from blood that remains in the placenta and umbilical cord after childbirth to treat a variety of illnesses, …
LA JOLLA, CA—Researchers at the Salk Institute for Biological Studies have developed a way to use patients’ own cells to potentially cure sickle cell disease and many other disorders caused …
LA JOLLA, CA—In principle, genetic engineering is simple, but in practice, replacing a faulty gene with a healthy copy is anything but. Using mutated versions of the lamin A gene …
LA JOLLA, CA—The current pace of population aging is without parallel in human history but surprisingly little is known about the human aging process, because lifespans of eight decades or …
LA JOLLA, CA—Bony fish like the tiny zebrafish have a remarkable ability that mammals can only dream of: if you lop off a chunk of their heart they swim sluggishly …
LA JOLLA, CA—The search for the holy grail of regenerative medicine—the ability to “grow back” a perfect body part when one is lost to injury or disease—has been under way …
LA JOLLA, CA—Umbilical cord blood cells can successfully be reprogrammed to function like embryonic stem cells, setting the basis for the creation of a comprehensive bank of tissue-matched, cord blood-derived …
LA JOLLA, CA—A collaborative study by researchers at the Salk Institute for Biological Studies uncovered that the tumor suppressor p53, which made its name as “guardian of the genome,” not …
La Jolla, CA—A study led by researchers at the Salk Institute for Biological Studies, has catapulted the field of regenerative medicine significantly forward, proving in principle that a human genetic …
La Jolla, CA — The Salk Institute for Biological Studies has been awarded a $6.6 million grant – the largest single award in the latest competition — by …
The first reports of the successful reprogramming of adult human cells back into so-called induced pluripotent stem (iPS) cells, which by all appearances looked and acted liked embryonic …
La Jolla, CA – Chop off a salamander’s leg and a brand new one will sprout in no time. But most animals have lost the ability to replace …
La Jolla, CA – Having your heart in the right place usually means having it located on the left side of your body. But just how a perfectly …
La Jolla, CA – Despite their celebrated “immortality,” the capacity of embryonic stem (ES) cells for endless division has its limits. After a very extended childhood spent …
La Jolla, CA – Humans and other animals may appear to be symmetrical on the outside, but symmetry is only skin deep. Many body organs, such as the stomach, the …
La Jolla, CA – In this week’s journal Nature, scientists at the Salk Institute for Biological Studies report that they have solved one of the ‘holy grail’ puzzles of developmental …
La Jolla, CA – Scientists at the Salk Institute have discovered a novel genetic pathway that ensures body organs develop correctly and in the right position during embryonic development. The …
La Jolla, CA – A Salk Institute team of biologists, mathematicians, and physicists has uncovered a novel paradigm for cell communication that provides new insights into the complex question of …
La Jolla, CA – Whether they’re wings, fins or legs, those appendages generally known as limbs play a critical role for lifting, grasping, moving and other activities needed to sustain …
La Jolla, CA – To make sure your heart’s in the right place, you need to add just the right amount of vitamin A.
According to new research led by scientists …
La Jolla, CA – A single gene can transform embryonic tissue destined to form a wing into a leg instead, Salk Institute investigators have found. Their studies were performed in …
La Jolla, CA – In a developing organism, knowledge of right from left can often mean the difference between life and death. Certainly, the direction and ultimate destination in which …
Bachelor's of Pharmacy and Science, University of Valencia
PhD, Universities of Bologna, Italy and Valencia, Spain
Postdoctoral Fellow, University of Marburg; The European Molecular Biology Laboratories at Heidelberg, Germany; University of California, Los Angeles
