Jan Karlseder, PhD
Professor
Molecular and Cell Biology Laboratory
Donald and Darlene Shiley Chair
Professor
Molecular and Cell Biology Laboratory
Donald and Darlene Shiley Chair
LA JOLLA—As we age, …
LA JOLLA—Just as plastic tips protect the ends of shoelaces and keep them from fraying when we tie them, molecular tips called telomeres protect the ends of chromosomes and keep …
LA JOLLA—A team of Salk Institute researchers led by President Rusty Gage has been awarded $19.2 million over eight years by the American Heart Association-Allen Initiative in Brain Health and …
LA JOLLA—Ever since researchers connected the shortening of telomeres—the protective structures on the ends of chromosomes—to aging and disease, the race has been on to understand the factors that govern …
LA JOLLA–Telomeres, specialized ends of our chromosomes that dictate how long cells can continue to duplicate themselves, have long been studied for their links to the aging process and cancer. …
LA JOLLA—The Salk Institute has received a $3 million gift from the Glenn Foundation for Medical Research to allow the Institute to continue conducting research to understand the biology of …
LA JOLLA, CA—Highly diverse cancers share one trait: the capacity for endless cell division. Unregulated growth is due in large part to the fact that tumor cells can rebuild protective …
LA JOLLA,CA—A team of scientists at the Salk Institute for Biological Studies has identified why disruption of a vital pathway in cell cycle control leads to the proliferation of cancer …
LA JOLLA, CA—For humans to grow and to replace and heal damaged tissues, the body’s cells must continually reproduce, a process known as “cell division,” by which one cell becomes …
LA JOLLA, CA—The Salk Institute is pleased to announce that professors E.J. Chichilnisky, Jan Karlseder, and Kuo-Fen Lee have each been selected as the recipient of an endowed chair to …
LA JOLLA, CA—Rapidly dividing cancer cells are skilled at patching up damage that would stop normal cells in their tracks, including wear and tear of telomeres, the protective caps at …
LA JOLLA, CA—The well-being of living cells requires specialized squads of proteins that maintain order. Degraders chew up worn-out proteins, recyclers wrap up damaged organelles, and-most importantly-DNA repair crews restitch …
LA JOLLA, CA—In stark contrast to normal cells, which only divide a finite number of times before they enter into a permanent state of growth arrest or simply die, cancer …
LA JOLLA, CA—After undergoing an extensive review process by Salk senior faculty, Non-Resident Fellows, and scientific leaders in their respective fields, Leanne Jones and Satchidananda Panda have been promoted to …
LA JOLLA, CA—Like cats, human cells have a finite number of lives-once they divide a certain number of times (thankfully, more than nine) they change shape, slow their pace, and …
La Jolla, CA – A team of scientists at the Salk Institute for Biological Studies has discovered that the roundworm C. elegans constructs the protective tips of its chromosomes – …
La Jolla, CA – Wielding a palette of chromosome paints, scientists at the Salk Institute for Biological Studies have taken a step closer to understanding the relationship between …
La Jolla, CA – When you dial 911 you expect rescuers to pull up at your front door, unload and get busy – not park the truck down …
La Jolla, CA – Researchers at the Salk Institute for Biological Studies discovered that cells co-opted the machinery that usually repairs broken strands of DNA to protect the integrity of …
La Jolla, CA – The continual and inevitable shortening of telomeres, the protective “caps” at the end of all 46 human chromosomes, has been linked to aging and physical decline. …
La Jolla, CA – Scientists at the Salk Institute have provided a startling insight into how cells age that might lead to new approaches for treating cancer and even aging …
BS, Biology, University of Innsbruck, Austria
PhD, Molecular Biology, University of Vienna
Postdoctoral Fellowship, The Rockefeller University, NY
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