Targeting telomeres, the timekeepers of cells, could improve chemotherapy
In an unexpected finding, the Salk Institute and collaborators show how disabling telomere protection during cell division prompts cell death.
Telomeres, specialized ends of our chromosomes that dictate how long cells can continue to duplicate themselves, have long been studied for their links to the aging process and cancer. Now, a discovery at the Salk Institute shows that telomeres may be more central than previously thought to a self-destruct program in cells that prevents tumors, a function that could potentially be exploited to improve cancer therapies. Read more »