La Jolla, CA – Salk scientists have obtained the first snapshot of how gene behavior varies among mammalian brains. The study employed “gene chip” technology to simultaneously compare the activities of approximately 13,000 genes in two inbred strains of mice.
La Jolla, CA – Richard A. Murphy, director of the Montreal Neurological Institute (MNI), has been named president and chief executive officer of The Salk Institute, effective October 1.
La Jolla, CA – A genetically engineered mouse, equipped with a human gene that senses potentially toxic substances in the body, including drugs, has been created by scientists at The Salk Institute.
La Jolla, CA – It’s a molecule that endows cancer cells with their pernicious ability to persevere.
La Jolla, CA – Before the moment of conception, living organisms experience another distinct birth – the creation of healthy eggs and sperm. Salk scientists recently obtained a peek at how genetic material is copied during the process, called meiosis, that produces these sex cells.
La Jolla, CA – Salk Institute neuroscientists have obtained the first evidence that specific genes control how the cortex forms functional units during development. The cortex is the most recently evolved part of the mammalian brain and, in humans, governs abstract reasoning and symbolic thought.
La Jolla, CA – Mice are not usually noted for their stalwart natures, but a new Salk Institute study shows that the loss of a single gene can render them especially anxious. The resulting “neurotic” mice approach new situations tentatively and appear to experience stress more acutely than normal mice.
La Jolla, CA – The first gene to control male fertility without affecting sexual behavior or physical appearance has been identified by Salk researchers. The study, appearing in the current Nature Genetics, demonstrates that a certain genetic mutation eliminates sperm development in male mice. It has no effect on females.
La Jolla, CA – A gene that speeds up the maturation process in plants, resulting in earlier development and flowering, has been isolated by a team of scientists at The Salk Institute.
La Jolla, CA – The living cell is the prototypical shape-shifter. At any given moment, it will reorganize itself to move, grow, replicate and even die.
La Jolla, CA – Should you hit the treadmill before hitting the books?
La Jolla, CA – To make sure your heart’s in the right place, you need to add just the right amount of vitamin A.
La Jolla, CA – A home movie of toddlers will show them wobble and weave, often to the amusement of adult viewers. But for babies born with the rare genetic disease ataxia-telangiectasia, commonly known as A-T, what may seem like normal and adorable lack of polish accelerates into a progressive and pervasive loss of muscle control and early death.
La Jolla, CA – The three-dimensional structure of a linchpin enzyme plants need to thrive – and one viewed as a key player in the growing nutraceutical market – has been revealed in atomic detail by scientists at The Salk Institute.
La Jolla, CA – During the turbulent ’60s, the phrases “flower power” and “petal power” were counterculture slogans that invoked peace and love. Though science has yet to design flowers capable of fulfilling the wishes of a bygone era, researchers at The Salk Institute are learning more about the genetic power behind flower formation that one day could yield designer blooms.
La Jolla, CA – Joseph R. Ecker, one of the nation’s leading authorities on the molecular biology and genetics of plants, will be joining the faculty of The Salk Institute, effective next summer.
La Jolla, CA – A single gene can transform embryonic tissue destined to form a wing into a leg instead, Salk Institute investigators have found. Their studies were performed in chickens, and the gene, called Tbx4 , appears to be involved in limb formation in mammals as well, including humans.