2020 PUBLICATIONS
Kim, R., Sejnowski, T.J. Strong inhibitory signaling underlies stable temporal dynamics and working memory in spiking neural networks. (2020) Nature Neuroscience. DOI: 10.1038/s41593-020-00753-w
Tsuda, B., Tye, K.M., Siegelmann, H.T., Sejnowski, T.J. A modeling framework for adaptive lifelong learning with transfer and savings through gating in the prefrontal cortex. (2020) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.2009591117
Peirs, C., Williams, S.G., Zhao, X., Arokiaraj, C.M., Ferreira, D.W., Noh, M.C., Smith, K.M., Halder, P., Corrigan, K.A., Gedeon, J.Y., Lee, S.J., Gatto, G., Chi, D., Ross, S.E., Goulding, M., Seal, R.P. Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury. (2020) Neuron. DOI: 10.1016/j.neuron.2020.10.027
Gatto, G., Bourane, S., Ren, X., Di Costanzo, S., Fenton, P.K., Halder, P., Seal, R.P., Goulding, M.D. A Functional Topographic Map for Spinal Sensorimotor Reflexes. (2020) Neuron. DOI: 10.1016/j.neuron.2020.10.003
Wang, Q.W., Lu, S.Y., Liu, Y.N., Chen, Y., Wei, H., Shen, W., Chen, Y.F., Fu, C.L., Wang, Y.H., Dai, A., Huang, X., Gage, F.H., Xu, Q., Yao, J. Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity. (2020) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.2016416117
Roome, R.B., Bourojeni, F.B., Mona, B., Rastegar-Pouyani, S., Blain, R., Dumouchel, A., Salesse, C., Thompson, W.S., Brookbank, M., Gitton, Y., Tessarollo, L., Goulding, M., Johnson, J.E., Kmita, M., Chédotal, A., Kania, A. Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. (2020) Cell Reports. 33(8):108425. DOI: 10.1016/j.celrep.2020.108425
Davis, W., Muller, L., Martinez-Trujillo, J., Sejnowski, T., Reynolds, J.H. Spontaneous travelling cortical waves gate perception in behaving primates (2020) Nature. DOI: https://www.nature.com/articles/s41586-020-2802-y.
Sejnowski, T. Charles Gross: Mentor, Maestro, Mensch. (2020) Progress in Neurobiology.:101926 DOI: 10.1016/j.pneurobio.2020.101926
Choi, S., Hachisuka, J., Brett, M.A., Magee, A.R., Omori, Y., Iqbal, N.U., Zhang, D., DeLisle, M.M., Wolfson, R.L., Bai, L., Santiago, C., Gong, S., Goulding, M., Heintz, N., Koerber, H.R., Ross, S.E., Ginty, D.D. Parallel ascending spinal pathways for affective touch and pain. [Pubmed] (2020) Nature.:https://rdcu.be/b9ulT DOI: 10.1038/s41586-020-2860-1
Linker, S.B., Randolph-Moore, L., Kottilil, K., Qiu, F., Jaeger, B.N., Barron, J., Gage, F.H. Identification of bona fide B2 SINE retrotransposon transcription through single-nucleus RNA-seq of the mouse hippocampus. (2020) Genome Research. DOI: 10.1101/gr.262196.120
Gonzalez, C.E., Lainscsek, C., Sejnowski, T.J., Letellier, C. Assessing observability of chaotic systems using Delay Differential Analysis. (2020) Chaos. 30(10):103113. DOI: 10.1063/5.0015533
Bersini, S., Schulte, R., Huang, L., Tsai, H., Hetzer, M.W. Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome. (2020) Elife. 9. DOI: 10.7554/eLife.54383
Sobczak, F., He, Y., Sejnowski, T.J., Yu, X. Predicting the fMRI Signal Fluctuation with Recurrent Neural Networks Trained on Vascular Network Dynamics. (2020) Cerebral Cortex . DOI: 10.1093/cercor/bhaa260
Abbott, L.F., Bock, D.D., Callaway, E.M., Denk, W., Dulac, C., Fairhall, A.L., Fiete, I., Harris, K.M., Helmstaedter, M., Jain, V., Kasthuri, N., LeCun, Y., Lichtman, J.W., Littlewood, P.B., Luo, L., Maunsell, J.H.R., Reid, R.C., Rosen, B.R., Rubin, G.M., Sejnowski, T.J., Seung, H.S., Svoboda, K., Tank, D.W., Tsao, D., Van Essen, D.C. The Mind of a Mouse. (2020) Cell. 182(6):1372-1376. DOI: 10.1016/j.cell.2020.08.010
Lin, T.W., Chen, Y., Bukhari, Q., Krishnan, G.P., Bazhenov, M., Sejnowski, T.J. Differential Covariance: A New Method to Estimate Functional Connectivity in fMRI. (2020) Neural Computation.:1-33 DOI: 10.1162/neco_a_01323
Yang, C.F., Kim, E.J., Callaway, E.M., Feldman, J.L. Monosynaptic Projections to Excitatory and Inhibitory preBötzinger Complex Neurons. (2020) Frontiers in Neuroanatomy. 14:58. DOI: 10.3389/fnana.2020.00058
Schiavon, C.R., Zhang, T., Zhao, B., Moore, A.S., Wales, P., Andrade, L.R., Wu, M., Sung, T.C., Dayn, Y., Feng, J.W., Quintero, O.A., Shadel, G.S., Grosse, R., Manor, U. Actin chromobody imaging reveals sub-organellar actin dynamics. (2020) Nature Methods. DOI: 10.1038/s41592-020-0926-5
Figueiredo, T., Mendes, A.P.D., Moreira, D.P., Goulart, E., Oliveira, D., Kobayashi, G.S., Stern, S., Kok, F., Marchetto, M.C., Santos, R., Gage, F.H., Zatz, M. Inositol monophosphatase 1 (IMPA1) mutation in intellectual disability patients impairs neurogenesis but not gliogenesis. (2020) Molecular Psychiatry. DOI: 10.1038/s41380-020-00862-9
Pan, X., Fang, L., Liu, J., Senay-Aras, B., Lin, W., Zheng, S., Zhang, T., Guo, J., Manor, U., Van Norman, J., Chen, W., Yang, Z. Auxin-induced signaling protein nanoclustering contributes to cell polarity formation. (2020) Nature Communications. 11(1):3914. DOI: 10.1038/s41467-020-17602-w
Boussaty, E.C., Gillard, D., Lavinsky, J., Salehi, P., Wang, J., Mendonça, A., Allayee, H., Manor, U., Friedman, R.A. The Genetics of Variation of the Wave 1 Amplitude of the Mouse Auditory Brainstem Response. (2020) J Assoc Res Otolaryngol. 21(4):323-336. DOI: 10.1007/s10162-020-00762-3
Kerman, B.E., Genoud, S., Kurt Vatandaslar, B., Denli, A.M., Ghosh, S.G., Xu, X., Yeo, G.W., Aimone, J.B., Gage, F.H. Motoneuron expression profiling identifies an association between an axonal splice variant of HDGF-related protein 3 and peripheral myelination. (2020) Journal of Biological Chemistry. DOI: 10.1074/jbc.RA120.014329
Ordyan, M., Bartol, T., Kennedy, M., Rangamani, P., Sejnowski, T. Interactions between calmodulin and neurogranin govern the dynamics of CaMKII as a leaky integrator. (2020) PLOS Computational Biology. 16(7):e1008015. DOI: 10.1371/journal.pcbi.1008015
DelGiorno, K.E., Chung, C.Y., Vavinskaya, V., Maurer, H.C., Novak, S.W., Lytle, N.K., Ma, Z., Giraddi, R.R., Wang, D., Fang, L., Naeem, R.F., Andrade, L.R., Ali, W.H., Tseng, H., Tsui, C., Gubbala, V.B., Ridinger-Saison, M., Ohmoto, M., Erikson, G.A., O'Connor, C., Shokhirev, M.N., Hah, N., Urade, Y., Matsumoto, I., Kaech, S.M., Singh, P.K., Manor, U., Olive, K.P., Wahl, G.M. Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2. (2020) Gastroenterology. DOI: 10.1053/j.gastro.2020.07.037
Ceto, S., Sekiguchi, K.J., Takashima, Y., Nimmerjahn, A., Tuszynski, M.H. Neural Stem Cell Grafts Form Extensive Synaptic Networks that Integrate with Host Circuits after Spinal Cord Injury. (2020) Cell Stem Cell. DOI: 10.1016/j.stem.2020.07.007
Goncalves, J., Bartol, T.M., Camus, C., Levet, F., Menegolla, A.P., Sejnowski, T.J., Sibarita, J.B., Vivaudou, M., Choquet, D., Hosy, E. Nanoscale co-organization and coactivation of AMPAR, NMDAR, and mGluR at excitatory synapses. (2020) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.1922563117
Mansour, A.A., Schafer, S.T., Gage, F.H. Cellular complexity in brain organoids: Current progress and unsolved issues. (2020) Seminars in Cell & Developmental Biology. DOI: 10.1016/j.semcdb.2020.05.013
Kang, H., Shokhirev, M.N., Xu, Z., Chandran, S., Dixon, J.R., Hetzer, M.W. Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation. (2020) Genes & Development. DOI: 10.1101/gad.335794.119
Filimon, F., Nelson, J.D., Sejnowski, T.J., Sereno, M.I., Cottrell, G.W. The ventral striatum dissociates information expectation, reward anticipation, and reward receipt. (2020) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.1911778117
Cho, U.H., Hetzer, M.W. Nuclear Periphery Takes Center Stage: The Role of Nuclear Pore Complexes in Cell Identity and Aging. (2020) Neuron. 106(6):899-911. DOI: 10.1016/j.neuron.2020.05.031
Bersini, S., Arrojo E Drigo, R., Huang, L., Shokhirev, M.N., Hetzer, M.W. Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease. (2020) Advanced Biosystems. 4(5):e2000044. DOI: 10.1002/adbi.202000044
Kim, E.J., Zhang, Z., Huang, L., Ito-Cole, T., Jacobs, M.W., Juavinett, A.L., Senturk, G., Hu, M., Ku, M., Ecker, J.R., Callaway, E.M. Extraction of Distinct Neuronal Cell Types from within a Genetically Continuous Population. (2020) Neuron. DOI: 10.1016/j.neuron.2020.04.018
Kirchgessner, M.A., Franklin, A.D., Callaway, E.M. Context-dependent and dynamic functional influence of corticothalamic pathways to first- and higher-order visual thalamus. (2020) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.2002080117
Badgley, M.A., Kremer, D.M., Maurer, H.C., DelGiorno, K.E., Lee, H.J., Purohit, V., Sagalovskiy, I.R., Ma, A., Kapilian, J., Firl, C.E.M., Decker, A.R., Sastra, S.A., Palermo, C.F., Andrade, L.R., Sajjakulnukit, P., Zhang, L., Tolstyka, Z.P., Hirschhorn, T., Lamb, C., Liu, T., Gu, W., Seeley, E.S., Stone, E., Georgiou, G., Manor, U., Iuga, A., Wahl, G.M., Stockwell, B.R., Lyssiotis, C.A., Olive, K.P. Cysteine depletion induces pancreatic tumor ferroptosis in mice. (2020) Science. 368(6486):85-89. DOI: 10.1126/science.aaw9872
Wenderski, W., Wang, L., Krokhotin, A., Walsh, J.J., Li, H., Shoji, H., Ghosh, S., George, R.D., Miller, E.L., Elias, L., Gillespie, M.A., Son, E.Y., Staahl, B.T., Baek, S.T., Stanley, V., Moncada, C., Shipony, Z., Linker, S.B., Marchetto, M.C.N., Gage, F.H., Chen, D., Sultan, T., Zaki, M.S., Ranish, J.A., Miyakawa, T., Luo, L., Malenka, R.C., Crabtree, G.R., Gleeson, J.G. Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism. (2020) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.1908238117
Sun, G., Chiuppesi, F., Chen, X., Wang, C., Tian, E., Nguyen, J., Kha, M., Trinh, D., Zhang, H., Marchetto, M.C., Song, H., Ming, G.L., Gage, F.H., Diamond, D.J., Wussow, F., Shi, Y. Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids. (2020) Cell Reports Medicine. 1(1):100002. DOI: 10.1016/j.xcrm.2020.100002
DAS, A., Cash, S.S., Sejnowski, T.J. Heterogeneity of Preictal Dynamics in Human Epileptic Seizures. (2020) IEEE Access. 8:52738-52748. DOI: 10.1109/access.2020.2981017
Shen, W., Wang, Q.W., Liu, Y.N., Marchetto, M.C., Linker, S., Lu, S.Y., Chen, Y., Liu, C., Guo, C., Xing, Z., Shi, W., Kelsoe, J.R., Alda, M., Wang, H., Zhong, Y., Sui, S.F., Zhao, M., Yang, Y., Mi, S., Cao, L., Gage, F.H., Yao, J. Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice. (2020) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.1918165117
DelGiorno, K.E., Naeem, R.F., Fang, L., Chung, C.Y., Ramos, C., Luhtala, N., O'Connor, C., Hunter, T., Manor, U., Wahl, G.M. Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis. (2020) Frontiers in Physiology. 11:88. DOI: 10.3389/fphys.2020.00088
Stern, S., Sarkar, A., Galor, D., Stern, T., Mei, A., Stern, Y., Mendes, A.P.D., Randolph-Moore, L., Rouleau, G., Bang, A.G., Santos, R., Alda, M., Marchetto, M.C., Gage, F.H. A Physiological Instability Displayed in Hippocampal Neurons Derived From Lithium-Nonresponsive Bipolar Disorder Patients. (2020) Biological Psychiatry. DOI: 10.1016/j.biopsych.2020.01.020
Bersini, S., Lytle, N.K., Schulte, R., Huang, L., Wahl, G.M., Hetzer, M.W. Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling. (2020) Life Science Alliance. 3(1). DOI: 10.26508/lsa.201900623
Sejnowski, T.J. The unreasonable effectiveness of deep learning in artificial intelligence. (2020) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.1907373117
Wang, M., Wei, P.C., Lim, C.K., Gallina, I.S., Marshall, S., Marchetto, M.C., Alt, F.W., Gage, F.H. Increased Neural Progenitor Proliferation in a hiPSC Model of Autism Induces Replication Stress-Associated Genome Instability. (2020) Cell Stem Cell. 26(2):221-233.e6 . DOI: 10.1016/j.stem.2019.12.013
Nimmerjahn, A. Monitoring neuronal health. (2020) Science. 367(6477):510-511. DOI: 10.1126/science.aba4472
