2018 PUBLICATIONS
Huang, T., Lin, S.H., Malewicz, N.M., Zhang, Y., Zhang, Y., Goulding, M., LaMotte, R.H., Ma, Q. Identifying the pathways required for coping behaviours associated with sustained pain. (2018) Nature. 565(7737):86-90. DOI: 10.1038/s41586-018-0793-8
Toyama, B.H., Arrojo E Drigo, R., Lev-Ram, V., Ramachandra, R., Deerinck, T.J., Lechene, C., Ellisman, M.H., Hetzer, M.W. Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells. (2018) Journal of Cell Biology. DOI: 10.1083/jcb.201809123
Fleischer, J.G., Schulte, R., Tsai, H.H., Tyagi, S., Ibarra, A., Shokhirev, M.N., Huang, L., Hetzer, M.W., Navlakha, S. Predicting age from the transcriptome of human dermal fibroblasts. (2018) Genome Biology. 19(1):221. DOI: 10.1186/s13059-018-1599-6
Kim, Y., Vadodaria, K.C., Lenkei, Z., Kato, T., Gage, F.H., Marchetto, M.C., Santos, R. MITOCHONDRIA, METABOLISM AND REDOX MECHANISMS IN PSYCHIATRIC DISORDERS. (2018) Antioxidants & Redox Signaling. DOI: 10.1089/ars.2018.7606
McCarthy, M.J., Wei, H., Nievergelt, C.M., Stautland, A., Maihofer, A.X., Welsh, D.K., Shilling, P., Alda, M., Alliey-Rodriguez, N., Anand, A., Andreasson, O.A., Balaraman, Y., Berrettini, W.H., Bertram, H., Brennand, K.J., Calabrese, J.R., Calkin, C.V., Claasen, A., Conroy, C., Coryell, W.H., Craig, D.W., D'Arcangelo, N., Demodena, A., Djurovic, S., Feeder, S., Fisher, C., Frazier, N., Frye, M.A., Gage, F.H., Gao, K., Garnham, J., Gershon, E.S., Glazer, K., Goes, F., Goto, T., Harrington, G., Jakobsen, P., Kamali, M., Karberg, E., Kelly, M., Leckband, S.G., Lohoff, F., McInnis, M.G., Mondimore, F., Morken, G., Nurnberger, J.I., Obral, S., Oedegaard, K.J., Ortiz, A., Ritchey, M., Ryan, K., Schinagle, M., Schoeyen, H., Schwebel, C., Shaw, M., Shekhtman, T., Slaney, C., Stapp, E., Szelinger, S., Tarwater, B., Zandi, P.P., Kelsoe, J.R. Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder. (2018) Neuropsychopharmacology . DOI: 10.1038/s41386-018-0273-8
Suh, H., Zhou, Q.G., Fernandez-Carasa, I., Clemenson, G.D., Pons-Espinal, M., Ro, E.J., Marti, M., Raya, A., Gage, F.H., Consiglio, A. Long-Term Labeling of Hippocampal Neural Stem Cells by a Lentiviral Vector. (2018) Frontiers in Molecular Neuroscience. 11:415. DOI: 10.3389/fnmol.2018.00415
Buchwalter, A., Kaneshiro, J.M., Hetzer, M.W. Coaching from the sidelines: the nuclear periphery in genome regulation. (2018) Nature Reviews Genetics. DOI: 10.1038/s41576-018-0063-5
Dhande, O.S., Stafford, B.K., Franke, K., El-Danaf, R., Percival, K.A., Phan, A.H., Li, P., Hansen, B.J., Nguyen, P.L., Berens, P., Taylor, W.R., Callaway, E., Euler, T., Huberman, A.D. Molecular fingerprinting of On-Off direction selective retinal ganglion cells across species and relevance to primate visual circuits. (2018) Journal of Neuroscience. DOI: 10.1523/JNEUROSCI.1784-18.2018
Kuhn, H.G., Toda, T., Gage, F.H. Adult hippocampal neurogenesis: a coming-of-age story. (2018) Journal of Neuroscience. DOI: 10.1523/JNEUROSCI.2144-18.2018
Reddy, G., Wong-Ng, J., Celani, A., Sejnowski, T.J., Vergassola, M. Glider soaring via reinforcement learning in the field. (2018) Nature. DOI: 10.1038/s41586-018-0533-0
Eftekharzadeh, B., Daigle, J.G., Kapinos, L.E., Coyne, A., Schiantarelli, J., Carlomagno, Y., Cook, C., Miller, S.J., Dujardin, S., Amaral, A.S., Grima, J.C., Bennett, R.E., Tepper, K., DeTure, M., Vanderburgh, C.R., Corjuc, B.T., DeVos, S.L., Gonzalez, J.A., Chew, J., Vidensky, S., Gage, F.H., Mertens, J., Troncoso, J., Mandelkow, E., Salvatella, X., Lim, R.Y.H., Petrucelli, L., Wegmann, S., Rothstein, J.D., Hyman, B.T. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. (2018) Neuron. 99(5):925-940.e7. DOI: 10.1016/j.neuron.2018.07.039
Choi, S.H., Bylykbashi, E., Chatila, Z.K., Lee, S.W., Pulli, B., Clemenson, G.D., Kim, E., Rompala, A., Oram, M.K., Asselin, C., Aronson, J., Zhang, C., Miller, S.J., Lesinski, A., Chen, J.W., Kim, D.Y., van Praag, H., Spiegelman, B.M., Gage, F.H., Tanzi, R.E. Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model. (2018) Science. 361(6406). DOI: 10.1126/science.aan8821
Mertens, J., Reid, D., Lau, S., Kim, Y., Gage, F.H. Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases. (2018) Annual Review of Genetics. 52:271-293. DOI: 10.1146/annurev-genet-120417-031534
McCloskey, A., Ibarra, A., Hetzer, M.W. Tpr regulates the total number of nuclear pore complexes per cell nucleus. (2018) Genes & Development. 32:1321-1331. DOI: 10.1101/gad.315523.118
Sejnowski, T. The prophet who foretold our future. (2018) Brain : A Journal of Neurology. 141(9):2820-2822. DOI: 10.1093/brain/awy212
Jaeger, B.N., Linker, S.B., Parylak, S.L., Barron, J.J., Gallina, I.S., Saavedra, C.D., Fitzpatrick, C., Lim, C.K., Schafer, S.T., Lacar, B., Jessberger, S., Gage, F.H. A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons. (2018) Nature Communications. 9(1):3084. DOI: 10.1038/s41467-018-05418-8
Zhang, Y., Liu, S., Zhang, Y.Q., Goulding, M., Wang, Y.Q., Ma, Q. Timing Mechanisms Underlying Gate Control by Feedforward Inhibition. (2018) Neuron. 99(5):941-955.e4. DOI: 10.1016/j.neuron.2018.07.026
van den Hurk, M., Erwin, J.A., Yeo, G.W., Gage, F.H., Bardy, C. Patch-Seq Protocol to Analyze the Electrophysiology, Morphology and Transcriptome of Whole Single Neurons Derived From Human Pluripotent Stem Cells. (2018) Frontiers in Molecular Neuroscience. 11:261. DOI: 10.3389/fnmol.2018.00261
Zhou, Y., Smith, B.H., Sharpee, T.O. Hyperbolic geometry of the olfactory space. (2018) Science Advances. 4(8):eaaq1458. DOI: 10.1126/sciadv.aaq1458
Sommer, A., Maxreiter, F., Krach, F., Fadler, T., Grosch, J., Maroni, M., Graef, D., Eberhardt, E., Riemenschneider, M.J., Yeo, G.W., Kohl, Z., Xiang, W., Gage, F.H., Winkler, J., Prots, I., Winner, B. Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease. (2018) Cell Stem Cell. 23(1):123-131.e6. DOI: 10.1016/j.stem.2018.06.015
Linker, S.B., Hsu, J.Y., Pfaff, A., Amatya, D., Ko, S.M., Voter, S., Wong, Q., Gage, F.H. BrainImageR: Spatiotemporal gene set analysis referencing the human brain. (2018) Bioinformatics. DOI: 10.1093/bioinformatics/bty618
Ernst, O.K., Bartol, T., Sejnowski, T., Mjolsness, E. Learning dynamic Boltzmann distributions as reduced models of spatial chemical kinetics. (2018) J Chem Phys. 149(3):034107. DOI: 10.1063/1.5026403
Haas, K.T., Compans, B., Letellier, M., Bartol, T.M., Grillo-Bosch, D., Sejnowski, T.J., Sainlos, M., Choquet, D., Thoumine, O., Hosy, E. Pre-post synaptic alignment through neuroligin-1 tunes synaptic transmission efficiency. (2018) Elife. 7. DOI: 10.7554/eLife.31755
Siddharth, Jung, T.P., Sejnowski, T.J. Multi-modal Approach for Affective Computing. (2018) Conf Proc IEEE Eng Med Biol Soc. 2018:291-294. DOI: 10.1109/EMBC.2018.8512320
Kronenberg, Z.N., Fiddes, I.T., Gordon, D., Murali, S., Cantsilieris, S., Meyerson, O.S., Underwood, J.G., Nelson, B.J., Chaisson, M.J.P., Dougherty, M.L., Munson, K.M., Hastie, A.R., Diekhans, M., Hormozdiari, F., Lorusso, N., Hoekzema, K., Qiu, R., Clark, K., Raja, A., Welch, A.E., Sorensen, M., Baker, C., Fulton, R.S., Armstrong, J., Graves-Lindsay, T.A., Denli, A.M., Hoppe, E.R., Hsieh, P., Hill, C.M., Pang, A.W.C., Lee, J., Lam, E.T., Dutcher, S.K., Gage, F.H., Warren, W.C., Shendure, J., Haussler, D., Schneider, V.A., Cao, H., Ventura, M., Wilson, R.K., Paten, B., Pollen, A., Eichler, E.E. High-resolution comparative analysis of great ape genomes. (2018) Science. 360(6393). DOI: 10.1126/science.aar6343
Krishnan, G.P., Rosen, B.Q., Chen, J.Y., Muller, L., Sejnowski, T.J., Cash, S.S., Halgren, E., Bazhenov, M. Thalamocortical and intracortical laminar connectivity determines sleep spindle properties. (2018) PLOS Computational Biology. 14(6):e1006171. DOI: 10.1371/journal.pcbi.1006171
Ueno, M., Nakamura, Y., Li, J., Gu, Z., Niehaus, J., Maezawa, M., Crone, S.A., Goulding, M., Baccei, M.L., Yoshida, Y. Corticospinal Circuits from the Sensory and Motor Cortices Differentially Regulate Skilled Movements through Distinct Spinal Interneurons. (2018) Cell Reports. 23(5):1286-1300.e7. DOI: 10.1016/j.celrep.2018.03.137
Sarkar, A., Mei, A., Paquola, A.C.M., Stern, S., Bardy, C., Klug, J.R., Kim, S., Neshat, N., Kim, H.J., Ku, M., Shokhirev, M.N., Adamowicz, D.H., Marchetto, M.C., Jappelli, R., Erwin, J.A., Padmanabhan, K., Shtrahman, M., Jin, X., Gage, F.H. Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro. (2018) Cell Stem Cell. 22(5):684-697.e9. DOI: 10.1016/j.stem.2018.04.009
Strnadel, J., Carromeu, C., Bardy, C., Navarro, M., Platoshyn, O., Glud, A.N., Marsala, S., Kafka, J., Miyanohara, A., Kato, T., Tadokoro, T., Hefferan, M.P., Kamizato, K., Yoshizumi, T., Juhas, S., Juhasova, J., Ho, C.S., Kheradmand, T., Chen, P., Bohaciakova, D., Hruska-Plochan, M., Todd, A.J., Driscoll, S.P., Glenn, T.D., Pfaff, S.L., Klima, J., Ciacci, J., Curtis, E., Gage, F.H., Bui, J., Yamada, K., Muotri, A.R., Marsala, M. Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs. (2018) Science Translational Medicine. 10(440). DOI: 10.1126/scitranslmed.aam6651
Stern, S., Linker, S., Vadodaria, K.C., Marchetto, M.C., Gage, F.H. Prediction of response to drug therapy in psychiatric disorders. (2018) Open Biology. 8(5). DOI: 10.1098/rsob.180031
Kim, Y., Zheng, X., Ansari, Z., Bunnell, M.C., Herdy, J.R., Traxler, L., Lee, H., Paquola, A.C.M., Blithikioti, C., Ku, M., Schlachetzki, J.C.M., Winkler, J., Edenhofer, F., Glass, C.K., Paucar, A.A., Jaeger, B.N., Pham, S., Boyer, L., Campbell, B.C., Hunter, T., Mertens, J., Gage, F.H. Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile. (2018) Cell Reports. 23(9):2550-2558. DOI: 10.1016/j.celrep.2018.04.105
Patriarchi, T., Cho, J.R., Merten, K., Howe, M.W., Marley, A., Xiong, W.H., Folk, R.W., Broussard, G.J., Liang, R., Jang, M.J., Zhong, H., Dombeck, D., von Zastrow, M., Nimmerjahn, A., Gradinaru, V., Williams, J.T., Tian, L. Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors. (2018) Science. DOI: 10.1126/science.aat4422
Mansour, A.A., Gonçalves, J.T., Bloyd, C.W., Li, H., Fernandes, S., Quang, D., Johnston, S., Parylak, S.L., Jin, X., Gage, F.H. An in vivo model of functional and vascularized human brain organoids. (2018) Nature Biotechnology. DOI: 10.1038/nbt.4127
Luo, L., Callaway, E.M., Svoboda, K. Genetic Dissection of Neural Circuits: A Decade of Progress. (2018) Neuron. 98(2):256-281. DOI: 10.1016/j.neuron.2018.03.040
Toda, T., Parylak, S.L., Linker, S.B., Gage, F.H. The role of adult hippocampal neurogenesis in brain health and disease. (2018) Molecular Psychiatry. DOI: 10.1038/s41380-018-0036-2
Kempermann, G., Gage, F.H., Aigner, L., Song, H., Curtis, M.A., Thuret, S., Kuhn, H.G., Jessberger, S., Frankland, P.W., Cameron, H.A., Gould, E., Hen, R., Abrous, D.N., Toni, N., Schinder, A.F., Zhao, X., Lucassen, P.J., Frisén, J. Human Adult Neurogenesis: Evidence and Remaining Questions. (2018) Cell Stem Cell. DOI: 10.1016/j.stem.2018.04.004
Ruiz-Martínez, , Bartol, T.M., Sejnowski, T.J., Tartakovsky, D.M. Efficient models of polymerization applied to FtsZ ring assembly in . (2018) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.1719391115
Moldakarimov, S., Bazhenov, M., Feldman, D.E., Sejnowski, T.J. Structured networks support sparse traveling waves in rodent somatosensory cortex. (2018) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.1710202115
Wang, X., Pinto-Duarte, A., Behrens, M.M., Zhou, X., Sejnowski, T.J. Ketamine independently modulated power and phase-coupling of theta oscillations in Sp4 hypomorphic mice. (2018) PLOS One. 13(3):e0193446. DOI: 10.1371/journal.pone.0193446
Mo, Z., Zhao, X., Liu, H., Hu, Q., Chen, X.Q., Pham, J., Wei, N., Liu, Z., Zhou, J., Burgess, R.W., Pfaff, S.L., Caskey, C.T., Wu, C., Bai, G., Yang, X.L. Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy. (2018) Nature Communications. 9(1):1007. DOI: 10.1038/s41467-018-03461-z
Gatto, G., Goulding, M. Locomotion Control: Brainstem Circuits Satisfy the Need for Speed. (2018) Current Biology. 28(6):R256-R259. DOI: 10.1016/j.cub.2018.01.068
Muller, L., Chavane, F., Reynolds, J., Sejnowski, T.J. Cortical travelling waves: mechanisms and computational principles. (2018) Nature Reviews Neuroscience. DOI: 10.1038/nrn.2018.20
Bedrosian, T.A., Quayle, C., Novaresi, N., Gage, F.H. Early life experience drives structural variation of neural genomes in mice. (2018) Science. 359(6382):1395-1399. DOI: 10.1126/science.aah3378
Zhang, Y., Kastner, D.B., Baccus, S.A., Sharpee, T.O. Optimal Information Transmission by Overlapping Retinal Cell Mosaics. (2018) Proc Conf Inf Sci Syst. 2018. DOI: 10.1109/ciss.2018.8362310
Zheng, Y., Shen, W., Zhang, J., Yang, B., Liu, Y.N., Qi, H., Yu, X., Lu, S.Y., Chen, Y., Xu, Y.Z., Li, Y., Gage, F.H., Mi, S., Yao, J. CRISPR interference-based specific and efficient gene inactivation in the brain. (2018) Nature Neuroscience. DOI: 10.1038/s41593-018-0077-5
Kaya, C., Cheng, M.H., Block, E.R., Bartol, T.M., Sejnowski, T.J., Sorkin, A., Faeder, J.R., Bahar, I. Heterogeneities in Axonal Structure and Transporter Distribution Lower Dopamine Reuptake Efficiency. (2018) eNeuro. 5(1). DOI: 10.1523/ENEURO.0298-17.2017
Bromer, C., Bartol, T.M., Bowden, J.B., Hubbard, D.D., Hanka, D.C., Gonzalez, P.V., Kuwajima, M., Mendenhall, J.M., Parker, P.H., Abraham, W.C., Sejnowski, T.J., Harris, K.M. Long-term potentiation expands information content of hippocampal dentate gyrus synapses. (2018) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.1716189115
Vadodaria, K.C., Amatya, D.N., Marchetto, M.C., Gage, F.H. Modeling psychiatric disorders using patient stem cell-derived neurons: a way forward. (2018) Genome Medicine. 10(1):1. DOI: 10.1186/s13073-017-0512-3
Wang, M., He, Y., Sejnowski, T.J., Yu, X. Brain-state dependent astrocytic Ca2+ signals are coupled to both positive and negative BOLD-fMRI signals. (2018) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.1711692115
Hayashi, M., Hinckley, C.A., Driscoll, S.P., Moore, N.J., Levine, A.J., Hilde, K.L., Sharma, K., Pfaff, S.L. Graded Arrays of Spinal and Supraspinal V2a Interneuron Subtypes Underlie Forelimb and Hindlimb Motor Control. (2018) Neuron. DOI: 10.1016/j.neuron.2018.01.023
Sharpee, T.O. (2018) Oxford Research Encyclopedias, Neuroscience.:1-23 DOI: doi.org/10.1093/acrefore/9780190264086.013.110
