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Cellular regeneration therapy restores damaged liver tissue faster than ever

Liver cells were partially reprogrammed into younger cells (red) using Yamanaka factors (white). The cell nuclei (blue) and cytoskeletal proteins (green) are also shown.Click here for a high-resolution image.Credit: Salk …

The protein that keeps the pancreas from digesting itself

LA JOLLA—Every day, your pancreas produces about one cup of digestive juices, a mixture of molecules that can break down the food you eat. But if these powerful molecules become …


Salk scientist Tony Hunter receives 2022 AACR Lifetime Achievement Award in Cancer Research

LA JOLLA—Salk Institute Professor Tony Hunter will receive the 2022 American Association for Cancer Research (AACR) Award for Lifetime Achievement in Cancer Research at the April annual meeting of AACR, …


Salk scientists receive 2022 Mark Foundation Endeavor Award to study lung cancer

LA JOLLA—Professors Reuben Shaw, Susan Kaech, Christian Metallo and Alan Saghatelian have received a 2022 Mark Foundation for Cancer Research Endeavor Award to support their research exploring the metabolic changes …


The Lustgarten Foundation and Salk Institute announce strategic pancreatic cancer research partnership

LA JOLLA/NEW YORK—The Lustgarten Foundation and Salk Institute today announced a new strategic partnership supported by a $5 million grant and focused on identifying and validating potential targets for new …


Salk scientists receive the 2021 ASPIRE award to study pancreatic cancer

LA JOLLA—Professor Ronald Evans and Assistant Professor Dannielle Engle have been granted a 2021 ASPIRE (Accelerating Scientific Platforms and Innovative Research) award to study the cellular and molecular drivers of …


Improving drug options for colorectal cancer patients

LA JOLLA—Patients with colorectal cancer were among the first to receive targeted therapies. These drugs aim to block the cancer-causing proteins that trigger out-of-control cell growth while sparing healthy tissues. …


Six Salk professors named among most highly cited researchers in the world

LA JOLLA—Salk Professors Joanne Chory, Joseph Ecker, Rusty Gage, Satchidananda Panda, Reuben Shaw and Kay Tye have been named to the Highly Cited Researchers list by Clarivate. The list identifies researchers who …


Uncovering how injury to the pancreas impacts cancer formation

Pancreatic acinar cells form a diverse population of new cell types in response to injury with the potential to limit or drive disease. Acinar-derived clones labeled in red and green.Click …

Salk scientists reveal most commonly mutated gene in all cancers

LA JOLLA—For the past fifteen years, cancer researchers have been using DNA sequencing technology to identify the gene mutations that cause different forms of cancer. Now, Salk Assistant Professor Edward …


Peter Adams and Gerald Shadel awarded $13 million from NIH to study aging and liver cancer

LA JOLLA—Sanford Burnham Prebys Professor Peter D. Adams, who directs the Aging, Cancer and Immuno-oncology Program, and Salk Institute Professor Gerald Shadel, who directs the San Diego Nathan Shock Center …


The Salk Institute and Sanford Burnham Prebys license ULK1/2 inhibitors to Endeavor BioMedicines for treatment of cancer

LA JOLLA—The Salk Institute, along with Sanford Burnham Prebys, have signed an exclusive licensing agreement with California-based Endeavor BioMedicines for an intellectual property portfolio relating to cancer therapeutics and diagnostics …


Salk promotes Diana Hargreaves to associate professor

LA JOLLA—The Salk Institute has promoted Diana Hargreaves to the rank of associate professor for her notable contributions in epigenetic regulation, which make specific regions of our DNA accessible to …


“Bad fat” suppresses killer T cells from attacking cancer

LA JOLLA—In order for cancer to grow and spread, it has to evade detection by our immune cells, particularly specialized “killer” T cells. Salk researchers led by Professor Susan Kaech …


Salk scientists reveal role of genetic switch in pigmentation and melanoma

LA JOLLA—Despite only accounting for about 1 percent of skin cancers, melanoma causes the majority of skin cancer-related deaths. While treatments for this serious disease do exist, these drugs can …


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