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Salk scientist Diana Hargreaves named Pew-Stewart Scholar for innovative cancer research

LA JOLLA – (June 14, 2019) Diana Hargreaves, an assistant professor in Salk’s Molecular and Cell Biology Laboratory, has been named a 2019 Pew-Stewart Scholar for Cancer Research as part …


New study targets Achilles’ heel of pancreatic cancer, with promising results

LA JOLLA—Advanced pancreatic cancer is often symptomless, leading to late diagnosis only after metastases have spread throughout the body. Additionally, tumor cells are encased in a “protective shield,” a microenvironment …


New role for a driver of metastatic cancers

LA JOLLA—Metastatic ovarian, prostate and breast cancers are notoriously difficult to treat and often deadly. Now, Salk Institute researchers have revealed a new role for the CDK12 protein. The findings …


Salk scientists uncover how high-fat diets drive colorectal cancer growth

LA JOLLA—As cancer death rates drop overall, doctors have noted a frightening anomaly: deaths from colorectal cancer in people under 55 appear to be creeping up. According to the American …


In surprising reversal, scientists find a cellular process that stops cancer before it starts

LA JOLLA—Just as plastic tips protect the ends of shoelaces and keep them from fraying when we tie them, molecular tips called telomeres protect the ends of chromosomes and keep …


Salk scientists uncover the health effects of metabolic “magic bullet” protein

LA JOLLA—The metabolic protein AMPK has been described as a kind of magic bullet for health. Studies in animal models have shown that compounds that activate the protein have health-promoting …


Maintaining the unlimited potential of stem cells

LA JOLLA—Embryonic stem cells (ESCs) are the very definition of being full of potential, given that they can become any type of cell in the body. Once they start down …


Genetic “whodunnit” for cancer gene solved

LA JOLLA—Long thought to suppress cancer by slowing cellular metabolism, the protein complex AMPK also seemed to help some tumors grow, confounding researchers. Now, Salk Institute researchers have solved the …


Dannielle Engle, rising star in pancreatic cancer research, to join Salk Institute

LA JOLLA—The Salk Institute is honored to welcome Dannielle Engle back to Salk as an assistant professor in the Salk Cancer Center. She is currently a senior fellow at Cold …


Tweaking cells’ gatekeepers could lead to new way to fight cancer

LA JOLLA—If the cell nucleus is like a bank for DNA, nuclear pores are the security doors around its perimeter. Yet more security doors aren’t necessarily better: some cancer cells …


New method of pinpointing cancer mutations could lead to more targeted treatments

LA JOLLA—Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective. Finding these mutations can …


A master switch controls aggressive breast cancer

LA JOLLA—A team at the Salk Institute has identified a master switch that appears to control the dynamic behavior of tumor cells that makes some aggressive cancers so difficult to …


Salk’s donors give $48.5 million to support scientific innovation in FY18

LA JOLLA—The Salk Institute announced today that it received more than $48 million from 1,100 individual donors and private grant makers in fiscal year 2018 to support the Institute’s groundbreaking …


Salk Institute receives $2 million for cancer research initiative

LA JOLLA—The Salk Institute announced a $2 million gift in support of its new Conquering Cancer Initiative from its current Board of Trustees Chair, Dan Lewis, and his wife, Martina …


What the satellites in your body do

LA JOLLA—Only some of us have satellite TV in our homes, but all of us have satellite DNA in cells in our bodies. Working copies of satellite DNA (called satellite …


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