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Salk News


Salk scientist Thomas Albright elected to National Academy of Sciences

La Jolla, CA – Salk Institute professor Thomas Albright, who studies the neuronal basis of visual perception, has been elected a member of the National Academy of Sciences. The Academy made the announcement today during its 145th annual meeting in Washington, DC. Election to the Academy recognizes distinguished and continuing achievements in original research, and is considered one of the highest honors accorded U.S. scientists.


AMPK signaling: Got food?

La Jolla, CA – A team of scientists at the Salk Institute for Biological Studies think they know how many-if not most-living organisms answer this question. They recently showed that when food supplies dwindle, mammals, fruitflies, or frogs probably activate the same ancient cell signaling pathway in order to conserve energy.


Charting the Epigenome

La Jolla, CA – Until recently, the chemical marks littering the DNA inside our cells like trees dotting a landscape could only be studied one gene at a time. But new high-throughput DNA sequencing technology has enabled researchers at the Salk Institute for Biological Studies to map the precise position of these individual DNA modifications throughout the genome of the plant Arabidopsis thaliana, and chart its effect on the activity of any of Arabidopsis‘ roughly 26,000 genes.


Sharing the road

La Jolla, CA – Come summer, we will once again marvel at the amazing athletic skills of Olympic athletes while in fact, the simple act of walking is no less remarkable. Just to prevent us from toppling over, the neuromuscular circuitry that controls all bodily movements relies on constant sensory feedback from the periphery to fine-tune its commands to hundreds of muscles.


The Salk Institute announces $10 million challenge gift from Irwin and Joan Jacobs

La Jolla, CA – The Salk Institute announced today that Irwin and Joan Jacobs have established a $10 million matching fund to support the creation of 10 Senior Scientist Endowed Chairs. By providing a match, this fund enables 10 donors to each make a gift of $2 million to create and name a highly prestigious and permanent chair. The Irwin and Joan Jacobs Leadership Challenge will add a $1 million match to each gift, thus providing each Chair with a $3 million endowment. Each named chair will provide key support to a Salk Institute Senior scientist.


A place in the sun

La Jolla, CA – Those spindly plants that desperately try to reach for a break in the canopy formed by larger plants all suffer from the same affliction: Shade avoidance syndrome or SAS. Now, the molecular details of SAS have been brought to light by researchers at the Salk Institute for Biological Studies.


Salk scientist wins 2007 Young Investigator’s Award in Gene Therapy for Cancer

La Jolla, CA – Dr. Clodagh O’Shea, an assistant professor in the Molecular and Cellular Biology Laboratory at the Salk Institute for Biological Studies, has been selected for the 2007 Young Investigator’s Award in Gene Therapy for Cancer. She will receive $500,000 over a three-year period to develop the “next generation oncolytic adenoviruses for p53-selective tumor therapy.”


Vicki Lundblad to receive 2008 Pearl Meister Greengard Prize

La Jolla, CA – The fifth annual Pearl Meister Greengard Prize, an international award to recognize outstanding women scientists, has been awarded to Salk professor Vicki Lundblad, Ph.D., for her groundbreaking work in telomere biology.


How worms protect their chromosomes: Thereby hangs a surprising tail

La Jolla, CA – A team of scientists at the Salk Institute for Biological Studies has discovered that the roundworm C. elegans constructs the protective tips of its chromosomes – known as telomeres – with a little more panache than do mammals, a finding that could deepen our understanding of the interrelationship of aging and cancer.


Chronically elevated blood sugar levels disable “fasting switch”

La Jolla, CA – Continually revved up insulin production, the kind that results from overeating and obesity, slowly dulls the body’s response to insulin. As a result, blood sugar levels start to creep up, setting the stage for diabetes-associated complications such as blindness, stroke and renal failure. To make matters even worse, chronically elevated blood sugar concentrations exacerbate insulin resistance.


UC San Diego and Salk Institute Establish Center to Study the Origin of Humans

La Jolla, CA – Perhaps the oldest question in the world is “where do I come from?”


New potential drug target for the treatment of atherosclerosis

La Jolla, CA – A nuclear receptor protein, known for controlling the ability of cells to burn fat, also exerts powerful anti-inflammatory effects in arteries, suppressing atherosclerosis in mice prone to developing the harmful plaques, according to new research by scientists at the Salk Institute for Biological Studies and the Harvard School of Public Health.


Salk researchers uncover molecular connection between excessive nutrient levels and insulin resistance

La Jolla, CA – For quite some time now, scientists suspected the so-called hexosamine pathway – a small side business of the main sugar processing enterprise inside a cell – to be involved in the development of insulin resistance. But they could never quite put their finger on the underlying mechanism.


PNAS article by Salk scientists wins 2007 Cozzarelli Prize

La Jolla, CA – The editors of the Proceedings of the National Academy of Sciences (PNAS) selected the article “Targeted delivery of proteins across the blood-brain barrier” by Brian J. Spencer, Ph.D. and Inder M. Verma, Ph.D., for the 2007 Cozzarelli Prize, which recognizes papers that reflect the highest standards of scientific excellence and originality.


Salk Researcher Receives Prestigious Sloan Research Fellowship

La Jolla, CA – Tatyana Sharpee, an assistant professor in the Laboratory for Computational Biology, has been named an Alfred P. Sloan Research Fellow. She will receive a grant of $50,000 for a two-year period.


Root or shoot? EAR calls the shots

La Jolla, CA – Controlled by a tightly regulated choreography that determines what should go up and what should go down, plants develop along a polar axis with a root on one end and a shoot on the other.


Dr. Inder Verma Named Recipient of the 2008 Vilcek Foundation Prize

La Jolla, CA – The Vilcek Foundation has named Salk professor Dr. Inder Verma as the recipient of its 2008 prize in biomedical science. The honor is awarded annually to foreign-born individuals for their extraordinary contributions to society in the United States.


Newborn brain cells modulate learning and memory

La Jolla, CA – Boosted by physical and mental exercise, neural stem cells continue to sprout new neurons throughout life, but the exact function of these newcomers has been the topic of much debate. Removing a genetic master switch that maintains neural stem cells in their proliferative state finally gave researchers at the Salk Institute for Biological Studies some definitive answers.


Trustee Donates $11.5 Million to the Salk Institute

La Jolla, CA – A gift of $11.5 million has been received on behalf of the Nomis Foundation, a European foundation being established by G.H. “Heini” Thyssen, a long-time friend and Trustee of the Salk Institute, to fund appointments for new investigators specialized in microbial pathogenesis and viral and cellular immunology. The gift, which will launch the Immunobiology and Microbial Pathogenesis program, fulfills a critical component of the Institute’s strategic scientific plan.


Ipsen and the Salk Institute Enter into Strategic Research Agreement

La Jolla, CA – Ipsen (Euronext:FR0010259150; IPN) and the Salk Institute for Biological Studies announced today that they will be signing a memorandum of understanding setting the framework for the creation of the Ipsen Life Sciences Program at the Salk Institute. The mission of the partnership is to advance knowledge in the field of proliferative and degenerative diseases through fundamental and applied biology research.