La Jolla, CA – Ronald M. Evans, Ph.D. known for his discoveries of genetic switches that link hormones to gene control, is this year’s recipient of the highly prestigious 2004 Lasker Award for Basic Medical Research, the Albert and Mary Lasker Foundation announced today.
La Jolla, CA – Researchers at the Salk Institute have successfully bioengineered resveratrol synthase from chalcone synthase, a biosynthetic protein enzyme found in all higher plants. Their findings appear in the September issue of Chemistry & Biology.
La Jolla, CA – A molecular switch known to regulate fat metabolism appears to prevent obesity and turns laboratory mice into marathon runners, a Salk Institute study has found.
La Jolla, CA – A molecule found in nearly all cells plays a vital role in kick-starting the production of key biological molecules involved in inflammation, a group of Salk Institute scientists has discovered. The finding, published in the June 25 issue of Science, may lead to new strategies for blocking the devastating inflammation that lies at the heart of autoimmune disorders such as multiple sclerosis, arthritis, lupus as well as some cancers.
La Jolla, CA – Adult stem cells in the brain can change their destiny and become blood vessel cells instead of nerve cells, a Salk Institute study has found.
La Jolla, CA – The ability of the AIDS virus to infect one species and bypass another may hinge on a single amino acid, a Salk Institute study has found. The work builds on the knowledge that HIV, the AIDS virus that infects humans, is relatively harmless to mice and even monkeys. The study furthers understanding of how HIV infects specific species while sparing others, and may help in the eventual development of novel drugs that halt the disease.
La Jolla, CA – A hormone that helps the body adapt to stress may provide a key to designing treatments for congestive heart failure, according to a study by researchers at the Salk Institute for Biological Studies and the University of California, San Diego (UCSD) School of Medicine.
La Jolla, CA – Researchers at the Salk Institute and the University of Geneva have discovered a novel mechanism to explain how the drug of abuse GHB affects the human nervous system. GHB is also known as the “date rape” drug.
La Jolla, CA – A brain-specific genetic switch protein known as a receptor has been found to control the fate of adult stem cells in the brain, according to a Salk Institute study.
La Jolla, CA – A Salk Institute team of biologists, mathematicians, and physicists has uncovered a novel paradigm for cell communication that provides new insights into the complex question of how the body determines where organs are placed.
La Jolla, CA – Nerve cells firing in spontaneous waves create the brain’s first sharp visual images during a short but critical phase of development, Salk Institute researchers have found. The study may lead to ways to better treat nerve cell injury and even treatments of diseases that occur in later life, like Parkinson’s.
La Jolla, CA – The Salk Institute has received a $7 million gift to establish a new center that will use computer-based computational biology methods to help unravel the complexities of the brain.
La Jolla, CA – Ronald Evans, the March of Dimes Chair in Developmental and Cell Biology at the Salk Institute, was named to the Institute of Medicine (IOM). Part of the U.S. National Academies, the IOM each year selects members who have made major contributions to furthering human health and advancing science.
La Jolla, CA – Salk Institute scientists have for the first time linked the function of a group of proteins required for DNA duplication and accurate chromosome movement during cell division. The findings may help explain the genetic influences behind some forms of cancer.