Marc Montminy

Professor

Clayton Foundation Laboratories for Peptide Biology

J.W. Kieckhefer Foundation Chair

Marc Montminy
Salk Institute for Biological Studies - News

News


Genetic switch turned on during fasting helps stop inflammation

LA JOLLA—A molecular pathway that is activated in the brain during fasting helps halt the spread of intestinal bacteria into the bloodstream, according to a new study by a team …


Sugar production switch in liver may offer target for new diabetes therapies

LA JOLLA, CA—In their extraordinary quest to decode human metabolism, researchers at the Salk Institute for Biological Studies have discovered a pair of molecules that regulates the liver’s production of …


Discovery of insulin switches in pancreas could lead to new diabetes drugs

LA JOLLA, CA—Researchers at the Salk Institute have discovered how a hormone turns on a series of molecular switches inside the pancreas that increases production of insulin.

The finding, published today …


Evolutionary conservation of fat metabolism pathways: Scientists say “if they ain’t broke, don’t fix ’em”

LA JOLLA, CA—By virtue of having survived, all animals-from flies to man-share a common expertise. All can distinguish times of plenty from famine and adjust their metabolism or behavior accordingly. …


Feast, famine, and the genetics of obesity: you can’t have it both ways

LA JOLLA, CA—In addition to fast food, desk jobs, and inertia, there is one more thing to blame for unwanted pounds-our genome, which has apparently not caught up with the …


Biologists Discover Biochemical Link Between Biological Clock and Diabetes

LA JOLLA, CA—Biologists have found that a key protein that regulates the biological clocks of mammals also regulates glucose production in the liver and that altering the levels of this …


The battle for CRTC2: how obesity increases the risk for diabetes

La Jolla, CA—Obesity is probably the most important factor in the development of insulin resistance, but science’s understanding of the chain of events is still spotty. Now, researchers …


Salk scientist Marc Montminy elected to National Academy of Sciences

La Jolla, CA – Salk researcher Marc R. Montminy, M.D., Ph.D., a professor in the Clayton Foundation Laboratories for Peptide Biology, has been elected a member of the …


Salk Launches Center for Nutritional Genomics with $5.5 Million Grant from Helmsley Trust

La Jolla, CA — The Salk Institute has received a $5.5 million grant from the Leona M. and Harry B. Helmsley Charitable Trust to launch the Salk …


Salk scientists detect molecular obesity link to insulin resistance, type II diabetes

La Jolla, CA—A molecular switch found in the fat tissue of obese mice is a critical factor in the development of insulin resistance, report scientists at the …


Food for thought–regulating energy supply to the brain during fasting

La Jolla, CA – If the current financial climate has taught us anything, it’s that a system where over-borrowing goes unchecked eventually ends in disaster. It turns out this rule …


Salk researchers find master switch in the brain that regulates desire for food and ability to reproduce

La Jolla, CA – Body weight and fertility have long known to be related to each other – women who are too thin, for example, can have trouble becoming pregnant. …


Salk Institute partners with the Foundation for Prader-Willi Research to study extreme obesity-related genetic disorder

La Jolla, CA – The Salk Institute for Biological Studies and the Foundation for Prader-Willi Research (FPWR) today announced a partnership that will forge new research to …


Life without TORC is one big struggle

La Jolla, CA – Humans and fruitflies – those pesky little buggers that are irresistibly attracted to overripe fruit – share more than a sweet tooth. Both rely on the …


Chronically elevated blood sugar levels disable “fasting switch”

La Jolla, CA – Continually revved up insulin production, the kind that results from overeating and obesity, slowly dulls the body’s response to insulin. As a result, blood sugar levels …


How insulin TORCs blood sugar levels: Glowing mice light the way

La Jolla, CA – With the help of genetically engineered mice whose livers turned into glowing light bulbs, researchers at the Salk Institute for Biological Studies have illuminated the underpinnings …


Salk scientists hammer out a pathway that promotes muscle cell survival in mice

La Jolla, CA – Scientists at the Salk Institute for Biological Studies have identified an enzyme that pumps up a cell’s ability to maintain healthy muscle and restores …


Chewing up a key regulator of fat synthesis keeps mice lean despite a high-fat diet

La Jolla, CA – Scientists at the Salk Institute for Biological Studies have identified a novel pathway that regulates the body’s ability to store or burn fat, a …


Key regulator of blood glucose levels discovered

La Jolla, CA – In many patients with type 2 diabetes, the liver acts like a sugar factory on overtime, churning out glucose throughout the day, even when blood sugar …


Salk Scientists Unlock Secret of Insulin Release

La Jolla, CA – A Salk Institute research team has made a discovery that provides valuable insight into a complication that is common among organ transplant patients and could eventually …


Molecular first steps to adult diabetes found

La Jolla, CA – A Salk Institute study has identified the first molecular steps that can lead to adult diabetes.

The study, published in the Nov. 13 issue of Nature, for …


Salk scientists find new potential target for diabetes treatment

La Jolla, CA – Salk scientists have identified a new potential drug target for type II diabetes that may offer a specific treatment to complement existing therapies. The new target, …


Education

BS, Biochemistry, Harvard University
MD, PhD, Physiology, Tufts University School of Medicine
Research Fellow in Medicine, Tufts-New England Medical Center, Boston


Awards & Honors

  • 2009 National Academy of Sciences
  • 1991 McKnight Neuroscience Development Award
  • 1990 Richard E. Weitzman Award, Endocrine Society