Print FriendlyNCI Cancer Center
The Cancer Center was established at the Salk Institute in 1970. It is a basic research Cancer Center Designated by the National Cancer Institute. The Director is Tony Hunter. The Cancer Center comprises about half of the research at the Salk Institute. The center includes 30 faculty members, 161 postdoctoral researchers, 70 graduate students and 150 research assistants. A Cancer Center Support (Core) Grant from the National Cancer Institute helps support many shared resources at the Salk Institute, including shared equipment, bioinformatics, functional genomics/quantitative PCR, proteomics, cytometry and imaging, peptide synthesis and transgenic facilities.
The original research programs in the Cancer Center emphasized tumor virology. As the center grew, the programs broadened to include various areas of molecular, cell, and developmental biology.
Over the past 30 years researchers in the Cancer Center have made important contributions to our understanding of cancer. Some of the most the influential discoveries include:
- Discovery of tyrosine phosphorylation and elaboration of its role in cell growth control.
- Identification of nuclear hormone receptors and elucidation of their role in physiology and development.
- Characterization of transcription factors that control gene expression and cell growth, differentiation, and patterning.
- Development of viral vectors for gene therapy.
In addition to excellence in research, the Cancer Center provides a supportive environment in which trainees and faculty members are encouraged to develop as independent investigators. Some of these scientists remain at the Salk Institute, while others move on to productive careers at other institutions.
Research in the Cancer Center is divided into three programs: Metabolism and Cancer, Mouse Models and Stem Cells, and Growth Control and Genomics Stability. Faculty members in each area are listed below.
Metabolism and Cancer |
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| Andrew Dillin | Ron Evans | Tony Hunter |
| Marc Montminy | Joseph Noel | Satchidananda Panda |
| David Schubert | Reuben Shaw | Wylie Vale |
Mouse Models and Stem Cells |
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| Senyon Choe | Fred Gage | Juan-Carlos Izpisúa Belmonte |
| Leanne Jones | Chris Kintner | Kuo-Fen Lee |
| Greg Lemke | Samuel Pfaff | John Thomas |
| Inder Verma | John Young | Ye Zheng |
Growth Control and Genomic Stability |
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| Beverly Emerson | Martin Hetzer | Katherine Jones |
| Jan Karlseder | Björn Lillemeier | Vicki Lundblad |
| Clodagh O'Shea | Geoffrey Wahl | |
| Lei Wang | ||