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Salk News


Gene Therapy Postpones Lou Gehrig’s Disease Symptoms

La Jolla, CA – A unique gene therapy method postpones the symptoms and nearly doubles the life span in a mouse animal model of Lou Gehrig’s disease, a research team led by the Salk Institute has found.


Missing Enzyme Found to Lead to Alzheimer?s Disease Symptoms

La Jolla, CA – An enzyme studied by scientists for years can prevent tangles of proteins from forming in the brain’s nerve cells – as occurs in patients with age-dependent Alzheimer’s disease, according to a study by investigators at the Salk Institute, Beth Israel Deaconess Medical Center and Harvard Medical School.


Salk Study Advances Understanding of Plant Genes and Their Function

La Jolla, CA – A Salk Institute study provides significant new information in the process of allowing scientists to understand the function of plant genes. The study is published in the August 1 issue of Science.


Leila Josefowicz to Perform at Symphony at Salk

La Jolla, CA – The eighth annual Symphony at Salk, a benefit for the Salk Institute for Biological Studies, will be held Saturday, Aug. 23, under the stars on the institute’s Gildred Court.


HIV Inactivates the Body’s Cellular Smart Bomb

La Jolla, CA – HIV eludes one of the body’s key smart bomb defenses against infection, and this finding may lay the groundwork for new drugs to treat AIDS, according to a new Salk Institute study.


Salk researcher wins major National Institutes of Health grant for work on brain-immune interactions, potential autoimmune disease treatments

La Jolla, CA – A Salk Institute scientist has been awarded a $3.3 million grant and the Jacob Javits Award from the National Institutes of Health (NIH) for his work in identifying how the immune and nervous systems interact to ward off disease, which may result in treatments for such autoimmune diseases as multiple sclerosis.


Salk Scientists Identify Pathway That Determines When Plants Flower

La Jolla, CA – Salk scientists have defined a new pathway that controls how plants flower in response to shaded, crowded conditions, and their findings may have implications for increasing yield in crops ranging from rice to wheat.


Cell Receptor Controls Body Fat Despite Food Consumption

La Jolla, CA – A cellular receptor that helps tailor responses to stress also keeps the body lean despite high-fat diets, a Salk Institute research team has found. But this leanness only appears under certain conditions, including a high-fat diet.


Salk Professor Ronald Evans Awarded Two Major Prizes

La Jolla, CA – Professor Ronald Evans, the March of Dimes Chair in Molecular and Developmental Biology, has received the 2003 March of Dimes Prize in Developmental Biology for his pioneering the molecular pathways that lead to the most common chronic diseases affecting humans. He has also been awarded the Alfred P. Sloan Prize, one of three awards given annually by the General Motors Cancer Research Foundation.


Male Sex Hormones Cooperate With Breast Cancer Gene To Suppress Tumors, Salk Scientists Find

La Jolla, CA – BRCA-2, a gene linked with breast and ovarian cancer, cooperates with male sex hormones to enhance its ability to activate transcription of genes, which may suppress tumor formation in normal cells, Salk Institute researchers have found.


Motor Nerve Cell “Factory” Findings May Elicit Treatments for Spinal Cord Injury, Disease

La Jolla, CA – Manufacturing motor nerve cells may someday be possible to help restore function in victims of spinal cord injury or such diseases of motion as Parkinson’s and Lou Gehrig’s disease or post-polio syndrome, a Salk Institute research study has found.


Salk Professor Thomas Albright Elected to American Academy of Arts and Sciences

La Jolla, CA – Thomas Albright, a Salk Institute professor of neuroscience and director of the vision center laboratory, was elected to the American Academy of Arts and Sciences. On May 5, the academy named 187 fellows and 29 foreign honorary members to the nation’s oldest learned society.


Salk Professor Fred H. Gage Elected to National Academy of Sciences

La Jolla, CA – Salk Institute Professor Fred H. Gage has been elected to the National Academy of Sciences. The election was held April 29 during the business session of the 140th annual meeting of the Academy. Election to membership in the academy is considered one of the highest honors that can be accorded a U.S. scientist or engineer.


Salk Researchers Find Receptor That Controls Obesity

La Jolla, CA – A cellular receptor that balances the accumulation of fat and fat burning in the body may be a new target for anti-obesity and cholesterol-fighting drugs, according to a Salk Institute study.


Gene Transfer Reduces Levels of Key Alzheimer’s Disease Protein

La Jolla, CA – A molecule that naturally degrades a protein linked to Alzheimer’s disease appears to reduce the levels of that protein by nearly 50 percent when delivered by gene therapy, researchers at the Salk Institute and UC San Diego have found in collaboration with researchers at the University of Kentucky. The findings appear in the March 15 issue of the Journal of Neuroscience.


Genetic Link May Tie Together Pesticides, ADHD, Gulf War syndrome and Other Disorders

La Jolla, CA – Research at the Salk Institute has identified a gene that may link certain pesticides and chemical weaponry to a number of neurological disorders, including the elusive Gulf War syndrome and attention deficit/hyperactivity disorder (ADHD).


Science Watch Ranks Salk Institute Scientists Among Nation’s Most Influential in Molecular Biology and Genetics Research

La Jolla, CA – The Salk Institute for Biological Studies has been ranked as one of the nation’s leaders in molecular biology and genetics research by a publication that monitors trends and performances in basic research.


Salk Institute and SUGEN Scientists Map ‘Human Kinome’

La Jolla, CA – A California research team has mapped an entire group of human enzymes, providing important information for the development of a new generation of drugs to treat cancer and other diseases. The findings will be published in the Dec. 6 issue of Science.


New Book Reveals Complexities Of The Human Mind

La Jolla, CA – Who are we? Are we good or fundamentally evil? What makes us happy? Who can we become? These are the questions prefacing a new book, Liars, Lovers, and Heroes: What the New Brain Science Reveals About How We Become Who We Are.


Salk Institute Professor Sydney Brenner Receives 2002 Nobel Prize for Medicine

La Jolla, CA – Sydney Brenner, a distinguished professor at the Salk Institute for Biological Studies, is one of three recipients of this year’s Nobel Prize in medicine for his contributions toward discoveries about how genes regulate organ growth and the process of programmed cell death.