San Diego Nathan Shock Center
Annual Workshop

Tackling the Heterogeneity of Aging

Salk Institute for Biological Studies - San Diego Nathan Shock Center
Annual Workshop - Tackling the Heterogeneity of Aging


Event date/time: March 25, 2022 from 9:00 a.m. PT to 3:30 p.m. PT (virtual); 5:00 p.m. PT (in-person)
Hosts: Alessandra Sacco (SBP) and Gerald Shadel (Salk Institute)
Program: Click here to download

8:30 a.m. Registration Check-in and Refreshments
9:00 a.m. Welcome/Introduction
9:10 a.m. Keynote: Meng Wang (Baylor College of Medicine)
Building multidisciplinary research in understanding aging biology
10:10 a.m. BREAK
10:15 a.m. 2021 SD-NSC Pilot Grant Projects

  • Vanessa Delcroix (The Scripps Research Institute)
    A single-cell atlas of the aging lacrimal gland to understand the mechanisms underlying age-associated dry eye disease
  • Lara Labarta Bajo (Salk)
    Astrocyte plasticity in the aging brain
  • Adam Konopka (University of Wisconsin-Madison)
    The metabolic-epigenomic network of metformin and exercise
  • Maria Clara Guida (SBP)
    Investigating the epigenetic drift of aging hearts using drosophila
  • Maria Mihaylova (The Ohio State University)
    Characterizing age-dependent changes in the mammalian colon
  • Ana Chucair-Elliot (Oklahoma Medical Research Foundation)
    A novel inducible cell-specific mouse model for chromatin accessibility and transcriptomic studies of retina Müller glia in age-related macular degeneration
11:30 a.m. Human Cell Models Core

  • Anthony Molina (UCSD)
    Clinical cohort
  • Jeffrey Jones (Salk)
    Human cell models of aging
12:00 p.m. LUNCH BREAK
12:40 p.m. Heterogeneity Core

  • Peter Adams (SBP)
    Spatial -omics at Salk and SBP
  • Uri Manor (Salk)
    Age-related changes to cochlear hair cell organelle morphology
  • Jolene Diedrich (Salk)
    Mass spectrometry
  • Nasun Hah (Salk)
    Sequencing and single cell analysis
1:30 p.m. Integrative Models Core

  • Tanya Sharpee, April Williams (Salk) – Introduction
  • Alexey Terskikh (SBP)
    Heterogeneity of epigenetic landscape at single cell level
2:00 p.m.
  • SD-NSC Services Q&A Breakout Sessions (virtual only)
    • Sequencing and single cell analysis – Nasun Hah
    • Mass spectrometry – Jolene Diedrich
    • Electron microscopy and imaging – Uri Manor
    • Integrative models – Tanya Sharpee, April Williams
  • SD-NSC Mentorship Meetings (in-person only, 2022 awardees)
2:30 p.m. BREAK
2:40 p.m. Career Development Panel

  • Academia: Timothy Huang, Assistant Professor at Sanford Burnham Prebys Medical Discovery Institute
  • Industry: Daniel Oliver, CEO and Co-Founder of RejuvenateBio
  • Core Facilities: Yoav Altman, Flow Cytometry Core Director at Sanford Burnham Prebys Medical Discovery Institute
  • Scientific Writing: Monica May, Communications Officer in the Department of Neurological Surgery at UCSD and Vice President of the San Diego Science Writers Association
3:25 p.m. Thank You and Closing Comments
3:30 p.m. Core Technologies Q&A (in-person only)
4:00 p.m. Networking Happy Hour (in-person only)