Tatyana Sharpee

Associate Professor

Computational Neurobiology Laboratory

Salk Institute for Biological Studies - Publications

all Publications


Atencio, C.A., Sharpee, T.O. Multidimensional receptive field processing by cat primary auditory cortical neurons. (2017) Neuroscience. 359:130-141. DOI: 10.1016/j.neuroscience.2017.07.003

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Sharpee, T.O. On texture, form, and fixational eye movements. (2017) Curr. Opin. Neurobiol. 46:228-233. DOI: 10.1016/j.conb.2017.09.002

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Kaardal, J.T., Theunissen, F.E., Sharpee, T.O. A Low-Rank Method for Characterizing High-Level Neural Computations. (2017) Frontiers in computational neuroscience. 11:68. DOI: 10.3389/fncom.2017.00068

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Sharpee, T.O. Optimizing Neural Information Capacity through Discretization. (2017) Neuron. 94(5):954-960. DOI: 10.1016/j.neuron.2017.04.044

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Rowekamp, R.J., Sharpee, T.O. Cross-orientation suppression in visual area V2. (2017) Nat Communications. 8:15739. DOI: 10.1038/ncomms15739

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Sharpee, T.O. Plasticity to the Rescue. (2016) Neuron. 92(5):935-936. DOI: 10.1016/j.neuron.2016.11.042

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Kuczala, A., Sharpee, T.O. Eigenvalue spectra of large correlated random matrices. (2016) Phys Rev E. 94(5-1):050101. DOI: 10.1103/PhysRevE.94.050101

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Sharpee, T.O. How Invariant Feature Selectivity Is Achieved in Cortex. (2016) Front Synaptic Neurosci. 8:26. DOI: 10.3389/fnsyn.2016.00026

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Sharpee, T.O. Taking a close look at electrosensing. (2016) Elife. 5. DOI: 10.7554/eLife.16209

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Zhang, Y., Sharpee, T.O. A Robust Feedforward Model of the Olfactory System. (2016) PLoS Comput. Biol. 12(4):e1004850. DOI: 10.1371/journal.pcbi.1004850

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Aljadeff, J., Renfrew, D., Vegué, M., Sharpee, T.O. Low-dimensional dynamics of structured random networks. (2016) Phys Rev E. 93(2):022302. DOI: 10.1103/PhysRevE.93.022302

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Hinckley, C.A., Alaynick, W.A., Gallarda, B.W., Hayashi, M., Hilde, K.L., Driscoll, S.P., Dekker, J.D., Tucker, H.O., Sharpee, T.O., Pfaff, S.L. Spinal Locomotor Circuits Develop Using Hierarchical Rules Based on Motorneuron Position and Identity. (2015) Neuron. 87(5):1008-21. DOI: 10.1016/j.neuron.2015.08.005

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Calhoun, A.J., Tong, A., Pokala, N., Fitzpatrick, J.A., Sharpee, T.O., Chalasani, S.H. Neural Mechanisms for Evaluating Environmental Variability in Caenorhabditis elegans. (2015) Neuron. 86(2):428-41. DOI: 10.1016/j.neuron.2015.03.026

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Aljadeff, J., Stern, M., Sharpee, T. Transition to chaos in random networks with cell-type-specific connectivity. (2015) Phys. Rev. Lett. 114(8):088101. DOI: 10.1103/PhysRevLett.114.088101

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Kastner, D.B., Baccus, S.A., Sharpee, T.O. Critical and maximally informative encoding between neural populations in the retina. (2015) Proc. Natl. Acad. Sci. U.S.A. 112(8):2533-8. DOI: 10.1073/pnas.1418092112

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Calhoun, A.J., Chalasani, S.H., Sharpee, T.O. Maximally informative foraging by Caenorhabditis elegans. (2014) Elife. 3. DOI: 10.7554/eLife.04220

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Sharpee, T.O. Toward functional classification of neuronal types. (2014) Neuron. 83(6):1329-34. DOI: 10.1016/j.neuron.2014.08.040

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Sharpee, T.O. Function determines structure in complex neural networks. (2014) Proc. Natl. Acad. Sci. U.S.A. 111(23):8327-8. DOI: 10.1073/pnas.1407198111


Sharpee, T.O., Calhoun, A.J., Chalasani, S.H. Information theory of adaptation in neurons, behavior, and mood. (2014) Curr. Opin. Neurobiol. 25:47-53. DOI: 10.1016/j.conb.2013.11.007

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Morris, R., Sancho-Martinez, I., Sharpee, T.O., Izpisua Belmonte, J.C. Mathematical approaches to modeling development and reprogramming. (2014) Proc. Natl. Acad. Sci. U.S.A. 111(14):5076-82. DOI: 10.1073/pnas.1317150111

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Aljadeff, J., Segev, R., Berry, M.J., Sharpee, T.O. Spike triggered covariance in strongly correlated gaussian stimuli. (2013) PLoS Comput. Biol. 9(9):e1003206. DOI: 10.1371/journal.pcbi.1003206

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Sharpee, T.O. Computational identification of receptive fields. (2013) Annu. Rev. Neurosci. 36:103-20. DOI: 10.1146/annurev-neuro-062012-170253

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Sharpee, T.O., Kouh, M., Reynolds, J.H. Trade-off between curvature tuning and position invariance in visual area V4. (2013) Proc. Natl. Acad. Sci. U.S.A. 110(28):11618-23. DOI: 10.1073/pnas.1217479110

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Kaardal, J., Fitzgerald, J.D., Berry, M.J., Sharpee, T.O. Identifying functional bases for multidimensional neural computations. (2013) Neural Comput. 25(7):1870-90. DOI: 10.1162/NECO_a_00465

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Nandy, A.S., Sharpee, T.O., Reynolds, J.H., Mitchell, J.F. The fine structure of shape tuning in area V4. (2013) Neuron. 78(6):1102-15. DOI: 10.1016/j.neuron.2013.04.016

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Saremi, S., Sejnowski, T.J., Sharpee, T.O. Double-gabor filters are independent components of small translation-invariant image patches. (2013) Neural Comput. 25(4):922-39. DOI: 10.1162/NECO_a_00418

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Jeanne, J.M., Sharpee, T.O., Gentner, T.Q. Associative learning enhances population coding by inverting interneuronal correlation patterns. (2013) Neuron. 78(2):352-63. DOI: 10.1016/j.neuron.2013.02.023

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Eickenberg, M., Rowekamp, R.J., Kouh, M., Sharpee, T.O. Characterizing responses of translation-invariant neurons to natural stimuli: maximally informative invariant dimensions. (2012) Neural Comput. 24(9):2384-421. DOI: 10.1162/NECO_a_00330

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Atencio, C.A., Sharpee, T.O., Schreiner, C.E. Receptive field dimensionality increases from the auditory midbrain to cortex. (2012) J. Neurophysiol. 107(10):2594-603. DOI: 10.1152/jn.01025.2011

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Sharpee, T.O. Adaptive switches in midbrain circuits. (2012) Neuron. 73(1):6-7. DOI: 10.1016/j.neuron.2011.12.017

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Fitzgerald, J.D., Rowekamp, R.J., Sincich, L.C., Sharpee, T.O. Second order dimensionality reduction using minimum and maximum mutual information models. (2011) PLoS Comput. Biol. 7(10):e1002249. DOI: 10.1371/journal.pcbi.1002249

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Sharpee, T.O., Nagel, K.I., Doupe, A.J. Two-dimensional adaptation in the auditory forebrain. (2011) J. Neurophysiol. 106(4):1841-61. DOI: 10.1152/jn.00905.2010

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Sharpee, T.O., Atencio, C.A., Schreiner, C.E. Hierarchical representations in the auditory cortex. (2011) Curr. Opin. Neurobiol. 21(5):761-7. DOI: 10.1016/j.conb.2011.05.027

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Rowekamp, R.J., Sharpee, T.O. Analyzing multicomponent receptive fields from neural responses to natural stimuli. (2011) Network. 22(1-4):45-73. DOI: 10.3109/0954898X.2011.566303

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Fitzgerald, J.D., Sincich, L.C., Sharpee, T.O. Minimal models of multidimensional computations. (2011) PLoS Comput. Biol. 7(3):e1001111. DOI: 10.1371/journal.pcbi.1001111

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Jeanne, J.M., Thompson, J.V., Sharpee, T.O., Gentner, T.Q. Emergence of learned categorical representations within an auditory forebrain circuit. (2011) J. Neurosci. 31(7):2595-606. DOI: 10.1523/JNEUROSCI.3930-10.2011

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Imaizumi, K., Priebe, N.J., Sharpee, T.O., Cheung, S.W., Schreiner, C.E. Encoding of temporal information by timing, rate, and place in cat auditory cortex. (2010) PLoS ONE. 5(7):e11531. DOI: 10.1371/journal.pone.0011531

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Gallarda, B.W., Sharpee, T.O., Pfaff, S.L., Alaynick, W.A. Defining rhythmic locomotor burst patterns using a continuous wavelet transform. (2010) Ann. N. Y. Acad. Sci. 1198:133-9. DOI: 10.1111/j.1749-6632.2010.05437.x

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Atencio, C.A., Sharpee, T.O., Schreiner, C.E. Hierarchical computation in the canonical auditory cortical circuit. (2009) Proc. Natl. Acad. Sci. U.S.A. 106(51):21894-9. DOI: 10.1073/pnas.0908383106

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Fitzgerald, J.D., Sharpee, T.O. Maximally informative pairwise interactions in networks. (2009) Phys Rev E Stat Nonlin Soft Matter Phys. 80(3 Pt 1):031914. DOI: 10.1103/PhysRevE.80.031914

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Liu, Y.S., Stevens, C.F., Sharpee, T.O. Predictable irregularities in retinal receptive fields. (2009) Proc. Natl. Acad. Sci. U.S.A. 106(38):16499-504. DOI: 10.1073/pnas.0908926106

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Sincich, L.C., Horton, J.C., Sharpee, T.O. Preserving information in neural transmission. (2009) J. Neurosci. 29(19):6207-16. DOI: 10.1523/JNEUROSCI.3701-08.2009

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Sharpee, T.O., Victor, J.D. Contextual modulation of V1 receptive fields depends on their spatial symmetry. (2009) Journal of computational neuroscience. 26(2):203-18. DOI: 10.1007/s10827-008-0107-5

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Kouh, M., Sharpee, T.O. Estimating linear-nonlinear models using Renyi divergences. (2009) Network. 20(2):49-68. DOI: 10.1080/09548980902950891

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Atencio, C.A., Sharpee, T.O., Schreiner, C.E. Cooperative nonlinearities in auditory cortical neurons. (2008) Neuron. 58(6):956-66. DOI: 10.1016/j.neuron.2008.04.026

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Sharpee, T.O., Miller, K.D., Stryker, M.P. On the importance of static nonlinearity in estimating spatiotemporal neural filters with natural stimuli. (2008) J. Neurophysiol. 99(5):2496-509. DOI: 10.1152/jn.01397.2007

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Clifford, C.W., Webster, M.A., Stanley, G.B., Stocker, A.A., Kohn, A., Sharpee, T.O., Schwartz, O. Visual adaptation: neural, psychological and computational aspects. (2007) Vision Res. 47(25):3125-31. DOI: 10.1016/j.visres.2007.08.023

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Sharpee, T.O. Comparison of information and variance maximization strategies for characterizing neural feature selectivity. (2007) Stat Med. 26(21):4009-31. DOI: 10.1002/sim.2931

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Sharpee, T., Bialek, W. Neural decision boundaries for maximal information transmission. (2007) PLoS ONE. 2(7):e646. DOI: 10.1371/journal.pone.0000646

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Sharpee, T.O., Sugihara, H., Kurgansky, A.V., Rebrik, S.P., Stryker, M.P., Miller, K.D. Adaptive filtering enhances information transmission in visual cortex. (2006) Nature. 439(7079):936-42. DOI: 10.1038/nature04519

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Victor, J.D., Mechler, F., Repucci, M.A., Purpura, K.P., Sharpee, T. Responses of V1 neurons to two-dimensional hermite functions. (2006) J. Neurophysiol. 95(1):379-400. DOI: 10.1152/jn.00498.2005

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Sharpee, T., Rust, N.C., Bialek, W. Analyzing neural responses to natural signals: maximally informative dimensions. (2004) Neural Comput. 16(2):223-50. DOI: 10.1162/089976604322742010

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Dykman, M.I., Sharpee, T., Platzman, P.M. Enhancement of tunneling from a correlated 2D electron system by a many-electron Mössbauer-type recoil in a magnetic field. (2001) Phys. Rev. Lett. 86(11):2408-11. DOI: 10.1103/PhysRevLett.86.2408

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Barabash-Sharpee, T., Dykman, M.I., Platzman, P.M. Tunneling transverse to a magnetic field and its occurrence in correlated 2D electron systems. (2000) Phys. Rev. Lett. 84(10):2227-30. DOI: 10.1103/PhysRevLett.84.2227

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Education

MS, Physics, Ukraine National University, Kiev, Ukraine
PhD, Physics, Michigan State University
Sloan-Swartz Postdoctoral Fellow, University of California, San Francisco


Awards & Honors

  • 2013 National Science Foundation (NSF) CAREER award
  • 2010 Helen McLoraine Developmental Chair in Neurobiology
  • 2009 W.M. Keck Foundation Research Excellence Award
  • 2009 McKnight Scholar
  • 2008 Searle Scholar