San Diego Nathan Shock Center

Heterogeneity of Aging

The overarching goal of the SD-NSC Heterogeneity of Aging Core is to enable investigations into the heterogeneity of aging over a broad range of scales (from molecules to organelles to single cells and tissues) by providing access to a diverse suite of analytical technologies. Major resources offered include the ability to:

• Obtain single-cell sequencing for transcriptomic and epigenetic analysis, high-end mass spectrometry services, and multimodal, high-resolution imaging for the analysis of the heterogeneity of cell and tissue aging studies.
• Receive advice on experimental design and high-resolution analysis related to single-cell transcriptomic and epigenetic approaches, and proteomic and metabolomic techniques with enhanced spatial and temporal resolution.
• Develop and disseminate novel methods and protocols, including artificial intelligence-based image processing algorithms.

Services and prices*

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Personnel and Contact Information

Nasun Hah, PhD

Director,
Next Generation Sequencing Core

Uri Manor, PhD

Assistant Research Professor

Director,
Waitt Advanced Biophotonics Core

Jolene Diedrich, PhD

Director,
Mass Spectrometry Core for Proteomics and Metabolomics

Antonio Michel Pinto, PhD

Senior Mass Spectrometry Specialist,
Mass Spectrometry Core for Proteomics and Metabolomics

Carolyn O’Connor

Managing Director,
Flow Cytometry Core