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Salk T32 Cancer Symposium 2022
The Tumor Ecosystem

Program

Salk Institute for Biological Studies - Salk T32 Cancer Symposium 2022
The Tumor Ecosystem - Program

Program

Salk T32 Cancer Symposium 2022 Program

*All times listed are Pacific Standard Time

8:30 a.m. – 9:30 a.m. Registration Check-in and Refreshments
9:30 a.m.– 9:40 a.m. Welcome/Introduction
9:40 a.m. – 10:15 a.m. Ellen Puré: “Fibroinflammatory Cells and Matrix Remodeling in Disease Progression and as Potential Therapeutic Targets in Tissue Fibrosis and Solid Tumors”
10:15 a.m. – 10:25 a.m. Nasiha Ahmed: “Bromodomain Protein 9 (BRD9) Regulates Interferon-stimulated Genes During Macrophage Activation via Cooperation with BET Protein BRD4”
10:25 a.m. – 10:35 a.m. Short Talk
Robert Saddawi-Konefka: “Tumor-Targeted Neoadjuvant Immunoradiotherapy Enhances Immunosurveillance from the Sentinel Lymph Node”
10:35 a.m. – 10:45 a.m. Break
10:50 a.m. – 11:25 a.m. (VIRTUAL) Robert Weinberg: “Effects of Epithelial-mesenchymal Polarization on Malignant Progression”
11:25 a.m.  – 11:35 a.m. Speed Talks

  • Gaurav Mendiratta: “Computational Modeling Identifies Mechanistic Differences Between Different Types of RAF Kinase Inhibitors”
  • Thomas Mann: “Chronic Agonism of Protein Kinase C Isozymes Drives Terminal Exhaustion in CD8 T cells”
  • Ryan Loughran: “Connecting Lysosomal Cholesterol Transport to p53 Null Cancer Growth Through PI5P4K Signaling”
  • Payel Mondal: “Metabolic Biomarkers for Circumventing Autophagy Inhibition in Cancer Cells”
11:40 a.m. – 12:15 p.m. (VIRTUAL) Troy McEachron: “Profiling the Immunooncology Landscape in Pediatric Osteosarcoma”
12:15 p.m.– 1:30 p.m. Lunch Break
1:35 p.m. – 2:10 p.m. Thomas Gajewski: “Microbiome and Germline Variants Regulate Anti-tumor Immunity Through Myeloid Cells”
2:10 p.m. – 2:20 p.m. Michael Trogdon: “Systems Modeling of Oncogeic RAS Signaling and Response to Targeted Therapy”
2:20 p.m. – 2:30 p.m. Short Talk
Matt Maxwell: “Loss of the ARID1A Tumor Suppressor Activates a ssDNA-STING Driven Type I Interferon Signaling Axis that Promotes Anti-Tumor Immunity”
2:30 p.m. – 2:40 p.m. Speed Talks

  • Tanja Eisemann: “CD4+ T cells Restrict Medulloblastoma Growth and Dissemination”
  • Jianfeng Huang: “Targeting Autophagy to Overcome Acquired Resistance to
    AMG-510 in KRAS G12C Mutant Cancer Cells”
  • Kailash Mangalhara: “Mitochondrial Succinate Regulates Antigen Presentation and Tumor Immune Responses”
  • Melissa Johnson: “Metabolic Determinants of Interferon Signaling in Melanoma”
2:45 p.m. – 3:20 p.m. Adrienne Boire: “Inflammatory Signaling Supports Cancer Cell Growth Within the Leptomeninges”
3:20 p.m. – 3:30 p.m. Thank you and Closing Comments
3:30 p.m. – 5:00 p.m. Poster Session and Reception in the Foyer, Salk Institute