LA JOLLA, CA—Ever find yourself racking your brain on a Monday morning to remember where you put your car keys?
LA JOLLA, CA—A team of scientists, including researchers from the Salk Institute for Biological Studies, has discovered that a drug used to treat canker sores appears to reverse obesity in mice. The findings, published February 10 in 自然医学, may lead to new weight-loss medications that could have an impact on growing obesity and diabetes rates in the United States.
The drug, amlexanox, has been on the market for more than 15 years. Different formulations of the drug are used in Japan to treat asthma and in the United States to treat canker sores. Human clinical trials for weight loss are expected to begin later this year.
LA JOLLA, CA—Scientists at the Salk Institute for Biological Studies have identified patterns of epigenomic diversity that not only allow plants to adapt to various environments, but could also benefit crop production and the study of human diseases.
Ian Trowbridge, an esteemed researcher who had been a member of the Salk faculty for almost three decades, passed away on Wednesday, February 6.
LA JOLLA, CA—You might think you have nothing in common with mustard except hotdogs. Yet based on research in a plant from the mustard family, Salk scientists have discovered a possible explanation for how organisms, including humans, directly regulate chemical reactions that quickly adjust the growth of organs. These findings overturn conventional views of how different body parts coordinate their growth, shedding light on the development of more productive plants and new therapies for metabolic diseases.
LA JOLLA, CA—In this week’s 自然方法, Salk researchers share a how-to secret for biologists: code for Amazon Cloud that significantly reduces the time necessary to process data-intensive microscopic images.
LA JOLLA, CA—Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, 鲁本-肖 has wondered if drugs originally designed to treat metabolic diseases could also work against cancer.
LA JOLLA, CA—The Salk Institute for Biological Studies has received a $42 million gift-the largest in the Institute’s history-to establish the Helmsley Center for Genomic Medicine (HCGM), a research center dedicated to decoding the common genetic factors underlying many complex chronic human diseases.
LA JOLLA, CA—For humans to grow and to replace and heal damaged tissues, the body’s cells must continually reproduce, a process known as “cell division,” by which one cell becomes two, two become four, and so on. A key question of biomedical research is how chromosomes, which are duplicated during cell division so that each daughter cell receives an exact copy of a person’s genome, are arranged during this process.
LA JOLLA, CA—When it’s dark, and we start to fall asleep, most of us think we’re tired because our bodies need rest. Yet circadian rhythms affect our bodies not just on a global scale, but at the level of individual organs, and even genes.
加州拉霍亚——一种从成熟细胞生成干细胞的新方法有望提高实验室中干细胞的产量，有助于清除再生医学疗法的一个障碍，该疗法将取代受损或不健康的身体组织。.
LA JOLLA,CA—Salk faculty members Joseph Ecker and Joseph Noel have been named as 2012 Fellows by the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and the publisher of the journal Science. Election as an AAAS Fellow is among the highest honors in American science and scholars are selected by their peers for “scientifically or socially distinguished efforts to advance science or its applications,” according to election administrators.
LA JOLLA,CA—The Salk Institute announced today that professors Edward M. Callaway 和 Joseph Noel have been appointed to endowed chairs in acknowledgment of their outstanding contributions and dedication to scientific research.
加州拉霍亚—第一个建筑评论家可能是金发姑娘。她抱怨有些东西太大，有些太小，而有些则“恰到好处”。那么，建筑师是如何确定什么是恰到好处的呢？为什么我们会瞬间感觉在某些空间里宾至如归，而在另一些空间里却从未感觉舒适合适呢？
LA JOLLA, CA—Growing evidence suggests that there may be a link between 糖尿病 和 Alzheimer’s disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. In a new study published in Aging Cell, researchers at the Salk Institute for Biological Studies show, for the first time, that diabetes enhances the development of aging features that may underlie early pathological events in Alzheimer’s.
LA JOLLA, CA—Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. In a paper published October 18 in 科学, however, researchers at the Salk Institute for Biological Studies have found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.
加利福尼亚州拉霍亚—通过对患有已知基因突变的帕金森病患者的皮肤细胞进行重新编程，索尔克生物研究所的研究人员发现，神经干细胞的损伤在该疾病中扮演着重要角色。这项研究结果于 2013 年 10 月 17 日在线发布于 自然, 可能带来诊断和治疗该疾病的新方法。.
LA JOLLA, CA—Cold viruses generally get a bad rap—which they’ve certainly earned—but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ally in the fight against cancer.
LA JOLLA, CA—Based on two new studies by researchers at the Salk Institute for Biological Studies, regeneration of a new limb or organ in a human will be much more difficult than the mad scientist and supervillain, Dr. Curt Connors, made it seem in the Amazing Spider-man comics and films.
LA JOLLA, CA—Salk scientists have identified a unique molecular signature in induced pluripotent stem cells (iPSCs), “reprogrammed” cells that show great promise in regenerative medicine thanks to their ability to generate a range of body tissues.
