洛杉矶-应对感染并不像杀死病原体那么简单。人体还需要仔细引导和监控其免疫反应，以防止附带损害。这种被称为疾病耐受性的调节对于在免疫系统正面应对感染时保护我们的组织至关重要。.
拉霍亚——年幼的心灵很容易塑造。每一次新的经历都会重塑孩子的大脑回路，在神经元之间添加和移除突触连接。这些连接模式会随着年龄增长而变得更加稳定，但生物学留出了一些灵活性，以确保成年人的大脑仍然能够根据需要进行调整和完善其回路。这种灵活性被称为 神经可塑性, ，我们学习、形成新记忆以及从伤病中恢复的能力都依赖于它。.
拉霍亚—医师、发明家和风险投资家安德鲁·“德鲁”·森耶伊（医学博士）已被新任命为索尔克研究所的 理事会. 他将与来自世界各地的商业和非营利组织领导人合作，共同推进索尔克研究所的基础和创新生物学研究。.
拉霍亚—一个生物体内的所有细胞都拥有完全相同的遗传序列。细胞类型之所以不同，是因为它们的 表观遗传学—精心放置的化学标记，影响着每个细胞中哪些基因被表达。表观遗传调控中的错误或失败可能导致动植物发育出现严重缺陷。这就产生了一个令人困惑的问题：如果表观遗传变化调节着我们的遗传，那么又是什么在调节它们呢？
拉霍亚—索尔克学会教员 约瑟夫·埃克尔,博士, 罗纳德·埃文斯, 博士，, 鲁斯蒂·盖奇,博士, 克里斯蒂安·梅塔洛, 博士，, 萨奇达南达·潘达, 博士，, 鲁本-肖, 博士，以及 凯泰, ，博士，以及研究助理约瑟夫·内里，都被提名为今年的 科睿唯安高被引研究员名单. 2025年榜单共有来自60个国家的6,868名研究人员，他们在各自的研究领域表现出“显著而广泛的影响力”。”
拉霍亚—海草保护我们的海洋，为海洋生物提供安全的港湾，能平息汹涌的海水，并储存过量的二氧化碳。全球有数十种海草保护海岸线，其中包括北美常见的鳗草，, Zostera marina. 但这些有益的水下草地正受到船只、挖泥、疾病和极端天气的威胁. 仅仅重新种植海草的恢复工作，失败率高达近一半——那么，接下来该怎么办？
洛杉矶--全球艾滋病毒感染率继续攀升。大约有 4000 万人感染了 HIV-1，这是最常见的 HIV 病毒株。虽然现在可以通过终身治疗更好地控制症状，但目前还没有完全清除体内病毒的治愈方法，因此患者仍然经常要与相关的健康问题、副作用、社会耻辱感和耐药性作斗争。.
拉霍亚—美国国立卫生研究院（NIH）已选择索尔克研究所神经科学家 特伦斯·塞津诺维奇, 博士，将于2025年获得 美国国立卫生研究院院长先驱奖. 这项享有盛誉的奖项授予提出极具创造性的、高风险高回报研究的科学家。.
拉霍亚约瑟夫·埃克尔, PhD, has been awarded the 2026 Barbara McClintock Prize for Plant Genetics and Genome Studies from the Maize Genetics Cooperation, a global organization of maize geneticists and breeders. The prize honors “the most outstanding plant scientists working on both genetics and genomics in the present era.” It is named after distinguished plant biologist Barbara McClintock, whose work in maize genetics earned her the 1983 Nobel Prize in Physiology or Medicine.
拉霍亚迪普希卡·拉马南, PhD, a scientist and assistant professor at the Salk Institute, has been awarded a New Innovators Award from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The five-year, $1.5 million grant will support Ramanan’s pioneering research on maternal immunity during pregnancy and lactation.
LA JOLLA—After nine months in the womb, humans enter a world filled with texture and shape. We must then quickly learn to recognize and respond to textures and objects in the outside world, beginning with sensations like the soft feel of a t-shirt or the doughy squish of a sandwich. By learning what touch sensations are innocuous, the brain can better recognize painful insults that might cause damage—think skinning a knee or stubbing a toe. But 7 to 10 percent of the global population develops mechanical allodynia, a form of chronic pain where innocuous light touch is perceived as painful.
LA JOLLA—Pancreatic cancer has the highest mortality rate of all major cancers, and its incidence is climbing. Because it is typically asymptomatic at early stages, pancreatic cancer is especially difficult to catch and treat in time. This allows the cancer to spread or metastasize throughout the body—the ultimate cause of death for nearly all patients.
LA JOLLA — Malnutrition is responsible for more than half of all deaths in children under the age of five worldwide. Those who survive can still experience lifelong consequences like cognitive and developmental delays, impaired academic performance, economic instability, and negative maternal health outcomes. This enormous public health issue demands solutions. The latest studies point to gut microbiome—the diverse bacteria, viruses, and other microbes living in our intestines—as a great place to start.
LA JOLLA—The Salk Institute mourns the loss of molecular biologist and Nobel laureate David Baltimore, a former research associate and longtime nonresident fellow at the Institute. Baltimore died on September 6, 2025, in Woods Hole, Massachusetts, at the age of 87.
LA JOLLA—A plant’s number one priority is to grow—a feat that demands sunlight, nutrients, and water. If just one of these three inputs is missing, like water in a drought, growth halts. You might then think that at the end of that drought, the plant would jump right back into growing. Instead, its priorities shift.
拉霍亚——正如蜜蜂通过授粉和使花朵绽放来给予花园生命一样，一种名为线粒体的小型细胞机器也赋予我们的身体生命，它们嗡嗡作响地产生能量，为我们细胞的每一项功能提供动力。维持线粒体代谢需要许多分子和蛋白质的参与——其中一些仍有待发现。.
LA JOLLA—The Salk Institute will welcome plant biologist Lucia Strader as a new professor and holder of the Howard H. and Maryam R. Newman Chair in Plant Biology in October 2025. Strader is an internationally recognized leader in plant hormone biology who was previously based at Duke University.
LA JOLLA—Nearly everything you know about plants was first discovered in a plant you’ve likely never heard of. 拟南芥, also known as thale cress, is a small, flowering weed that has shaped much of plant biology as we know it. Serving as the representative plant species in most plant research across the last half century, Arabidopsis has taught us how plants respond to light, which hormones control plant behavior, and why some plants grow long, deep roots while others grow them shallow and wide. But despite its beloved reputation among plant biologists worldwide, many elements of the Arabidopsis life cycle have remained a mystery.
LA JOLLA—The Salk Institute will welcome immunologist Jamie Blum as a NOMIS Assistant Professor in September 2025. Blum investigates how the immune system interprets what we eat—specifically, why some foods trigger harmful allergic responses while others are accepted as safe.
LA JOLLA—The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide. This prevalent condition is also linked to other metabolic disorders, including type 2 diabetes, cardiovascular diseases, chronic kidney disease, and cancers. Current treatment options include lifestyle interventions, bariatric surgery, and GLP-1 drugs like Ozempic or Wegovy, but many patients struggle to access or complete these treatments or to maintain their weight loss afterwards.
