Waitt Advanced Biophotonics Center

Ruiz, S., Brennand, K., Panopoulos, A.D., Herrerías, A., Gage, F.H., Izpisua-Belmonte, J.C. High-efficient generation of induced pluripotent stem cells from human astrocytes. (2010) PLOS One. 5(12):e15526. DOI: 10.1371/journal.pone.0015526

Wall, N.R., Wickersham, I.R., Cetin, A., De La Parra, M., Callaway, E.M. Monosynaptic circuit tracing in vivo through Cre-dependent targeting and complementation of modified rabies virus. (2010) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 107(50):21848-21853. DOI: 10.1073/pnas.1011756107

Timofeev, I., Bazhenov, M., Seigneur, J., Sejnowski, T. Neocortical synchronization. (2010) Epilepsia. 51(Suppl 5):18. DOI: 10.1111/j.1528-1167.2010.02804.x

Weible, A.P., Schwarcz, L., Wickersham, I.R., Deblander, L., Wu, H., Callaway, E.M., Seung, H.S., Kentros, C.G. Transgenic targeting of recombinant rabies virus reveals monosynaptic connectivity of specific neurons. (2010) Journal of Neuroscience. 30(49):16509-16513. DOI: 10.1523/JNEUROSCI.2442-10.2010

Hill, E.S., Moore-Kochlacs, C., Vasireddi, S.K., Sejnowski, T.J., Frost, W.N. Validation of independent component analysis for rapid spike sorting of optical recording data. (2010) Journal für Neurophysiologie. 104(6):3721-3731. DOI: 10.1152/jn.00691.2010

Sejnowski, T.J. Learning optimal strategies in complex environments. (2010) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 107(47):20151-2. DOI: 10.1073/pnas.1014954107

Marchetto, M.C., Carromeu, C., Acab, A., Yu, D., Yeo, G.W., Mu, Y., Chen, G., Gage, F.H., Muotri, A.R. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. (2010) Zelle. 143(4):527-39. DOI: 10.1016/j.cell.2010.10.016

Coggan, J.S., Prescott, S.A., Bartol, T.M., Sejnowski, T.J. Imbalance of ionic conductances contributes to diverse symptoms of demyelination. (2010) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 107(48):20602-20609. DOI: 10.1073/pnas.1013798107

Mathews, E.A., Morgenstern, N.A., Piatti, V.C., Zhao, C., Jessberger, S., Schinder, A.F., Gage, F.H. A distinctive layering pattern of mouse dentate granule cells is generated by developmental and adult neurogenesis. (2010) Journal of Vergleichende Neurologie. 518(22):4479-90. DOI: 10.1002/cne.22489

Heider, B., Nathanson, J.L., Isacoff, E.Y., Callaway, E.M., Siegel, R.M. Two-photon imaging of calcium in virally transfected striate cortical neurons of behaving monkey. (2010) PLOS One. 5(11). DOI: 10.1371/journal.pone.0013829

Haubensak, W., Kunwar, P.S., Cai, H., Ciocchi, S., Wall, N.R., Ponnusamy, R., Biag, J., Dong, H.W., Deisseroth, K., Callaway, E.M., Fanselow, M.S., Lüthi, A., Anderson, D.J. Genetic dissection of an amygdala microcircuit that gates conditioned fear. (2010) Natur. 468(7321):270-276. DOI: 10.1038/nature09553

Tiesinga, P.H., Sejnowski, T.J. Mechanisms for Phase Shifting in Cortical Networks and their Role in Communication through Coherence. (2010) Frontiers in Human Neuroscience. 4:196. DOI: 10.3389/fnhum.2010.00196

Nadkarni, S., Bartol, T.M., Sejnowski, T.J., Levine, H. Modelling vesicular release at hippocampal synapses. (2010) PLOS Computational Biology. 6(11):e1000983. DOI: 10.1371/journal.pcbi.1000983

Volman, V., Levine, H., Sejnowski, T.J. Shunting inhibition controls the gain modulation mediated by asynchronous neurotransmitter release in early development. (2010) PLOS Computational Biology. 6(11):e1000973. DOI: 10.1371/journal.pcbi.1000973

Sejnowski, T.J. QnAs with Terrence J. Sejnowski. [Interviewed by Prashant Nair]. (2010) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 107(48):20601. DOI: 10.1073/pnas.1015459107

Muotri, A.R., Marchetto, M.C., Coufal, N.G., Oefner, R., Yeo, G., Nakashima, K., Gage, F.H. L1 retrotransposition in neurons is modulated by MeCP2. (2010) Natur. 468(7322):443-6. DOI: 10.1038/nature09544

Ma, D.K., Marchetto, M.C., Guo, J.U., Ming, G.L., Gage, F.H., Song, H. Epigenetic choreographers of neurogenesis in the adult mammalian brain. (2010) Nature Neuroscience. 13(11):1338-44. DOI: 10.1038/nn.2672

Aimone, J.B., Deng, W., Gage, F.H. Put them out to pasture? What are old granule cells good for, anyway...? (2010) Hippocampus. 20(10):1124-5. DOI: 10.1002/hipo.20867

Miller, K.J., Hermes, D., Honey, C.J., Sharma, M., Rao, R.P., den Nijs, M., Fetz, E.E., Sejnowski, T.J., Hebb, A.O., Ojemann, J.G., Makeig, S., Leuthardt, E.C. Dynamic modulation of local population activity by rhythm phase in human occipital cortex during a visual search task. (2010) Frontiers in Human Neuroscience. 4:197. DOI: 10.3389/fnhum.2010.00197

Liu, D., Ou, L., Clemenson, G.D., Chao, C., Lutske, M.E., Zambetti, G.P., Gage, F.H., Xu, Y. Puma is required for p53-induced depletion of adult stem cells. (2010) Nature Cell Biology. 12(10):993-8. DOI: 10.1038/ncb2100

Hasenstaub, A.R., Callaway, E.M. Paint it black (or red, or green): optical and genetic tools illuminate inhibitory contributions to cortical circuit function. (2010) Neuron. 67(5):681-684. DOI: 10.1016/j.neuron.2010.08.039

Choi, J., Young, J.A., Callaway, E.M. Selective viral vector transduction of ErbB4 expressing cortical interneurons in vivo with a viral receptor-ligand bridge protein. (2010) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 107(38):16703-16708. DOI: 10.1073/pnas.1006233107

Petruska, J.C., Kitay, B., Boyce, V.S., Kaspar, B.K., Pearse, D.D., Gage, F.H., Mendell, L.M. Intramuscular AAV delivery of NT-3 alters synaptic transmission to motoneurons in adult rats. (2010) Eur. J. Neurosci. 32(6):997-1005. DOI: 10.1111/j.1460-9568.2010.07392.x

Hao, J., Lee, T.W., Sejnowski, T.J. Speech Enhancement Using Gaussian Scale Mixture Models. (2010) IEEE Trans Audio Speech Lang Process. 18(6):1127-1136. DOI: 10.1109/TASL.2009.2030012

Marshel, J.H., Mori, T., Nielsen, K.J., Callaway, E.M. Targeting single neuronal networks for gene expression and cell labeling in vivo. (2010) Neuron. 67(4):562-574. DOI: 10.1016/j.neuron.2010.08.001

Fröhlich, F., Sejnowski, T.J., Bazhenov, M. Network bistability mediates spontaneous transitions between normal and pathological brain states. (2010) Journal of Neuroscience. 30(32):10734-10743. DOI: 10.1523/JNEUROSCI.1239-10.2010

Mu, Y., Lee, S.W., Gage, F.H. Signaling in adult neurogenesis. (2010) Aktuelle Meinungen in der Neurobiologie. 20(4):416-23. DOI: 10.1016/j.conb.2010.04.010

Singer, T., McConnell, M.J., Marchetto, M.C., Coufal, N.G., Gage, F.H. LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes? (2010) Trends in der Neurowissenschaft. 33(8):345-54. DOI: 10.1016/j.tins.2010.04.001

Valdez, G., Tapia, J.C., Kang, H., Clemenson, G.D., Gage, F.H., Lichtman, J.W., Sanes, J.R. Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise. (2010) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 107(33):14863-8. DOI: 10.1073/pnas.1002220107

Mira, H., Andreu, Z., Suh, H., Lie, D.C., Jessberger, S., Consiglio, A., San Emeterio, J., Hortigüela, R., Marqués-Torrejón, M.A., Nakashima, K., Colak, D., Götz, M., Fariñas, I., Gage, F.H. Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. (2010) Cell Stem Cell. 7(1):78-89. DOI: 10.1016/j.stem.2010.04.016

Hasenstaub, A., Otte, S., Callaway, E., Sejnowski, T.J. Metabolic cost as a unifying principle governing neuronal biophysics. (2010) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 107(27):12329-34. DOI: 10.1073/pnas.0914886107

Aimone, J.B., Deng, W., Gage, F.H. Adult neurogenesis: integrating theories and separating functions. (2010) Trends in Cognitive Sciences. 14(7):325-37. DOI: 10.1016/j.tics.2010.04.003

Imaizumi, K., Priebe, N.J., Sharpee, T.O., Cheung, S.W., Schreiner, C.E. Encoding of temporal information by timing, rate, and place in cat auditory cortex. (2010) PLOS One. 5(7):e11531. DOI: 10.1371/journal.pone.0011531

Qu, Y., Glasco, D.M., Zhou, L., Sawant, A., Ravni, A., Fritzsch, B., Damrau, C., Murdoch, J.N., Evans, S., Pfaff, S.L., Formstone, C., Goffinet, A.M., Chandrasekhar, A., Tissir, F. Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. (2010) Journal of Neuroscience. 30(28):9392-401. DOI: 10.1523/JNEUROSCI.0124-10.2010

Nelson, J.D., McKenzie, C.R., Cottrell, G.W., Sejnowski, T.J. Experience matters: information acquisition optimizes probability gain. (2010) Psychol Sci. 21(7):960-969. DOI: 10.1177/0956797610372637

Grossmann, K.S., Giraudin, A., Britz, O., Zhang, J., Goulding, M. Genetic dissection of rhythmic motor networks in mice. (2010) Fortschritte in der Hirnforschung. 187:19-37. DOI: 10.1016/B978-0-444-53613-6.00002-2

Gallarda, B.W., Sharpee, T.O., Pfaff, S.L., Alaynick, W.A. Defining rhythmic locomotor burst patterns using a continuous wavelet transform. (2010) Ann. N. Y. Acad. Sci. 1198:133-9. DOI: 10.1111/j.1749-6632.2010.05437.x

Hao, J., Lee, I., Lee, T.W., Sejnowski, T.J. Independent vector analysis for source separation using a mixture of gaussians prior. (2010) Neural Computation. 22(6):1646-1673. DOI: 10.1162/neco.2010.11-08-906

Deng, W., Aimone, J.B., Gage, F.H. New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? (2010) Nature Reviews Neuroscience. 11(5):339-50. DOI: 10.1038/nrn2822

Moldakarimov, S., Bazhenov, M., Sejnowski, T.J. Representation sharpening can explain perceptual priming. (2010) Neural Computation. 22(5):1312-32. DOI: 10.1162/neco.2009.04-09-999

Zhang, M., Liu, J., Kim, Y., Dixon, J.E., Pfaff, S.L., Gill, G.N., Noel, J.P., Zhang, Y. Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1. (2010) Protein Science. 19(5):974-86. DOI: 10.1002/pro.375

Modchang, C., Nadkarni, S., Bartol, T.M., Triampo, W., Sejnowski, T.J., Levine, H., Rappel, W.J. A comparison of deterministic and stochastic simulations of neuronal vesicle release models. (2010) Phys Biol. 7(2):026008. DOI: 10.1088/1478-3975/7/2/026008

Marchetto, M.C., Winner, B., Gage, F.H. Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases. (2010) Human Molecular Genetics. 19(R1):R71-6. DOI: 10.1093/hmg/ddq159

Wang, H.P., Spencer, D., Fellous, J.M., Sejnowski, T.J. Synchrony of thalamocortical inputs maximizes cortical reliability. (2010) Wissenschaft. 328(5974):106-109. DOI: 10.1126/science.1183108

Tronel, S., Fabre, A., Charrier, V., Oliet, S.H., Gage, F.H., Abrous, D.N. Spatial learning sculpts the dendritic arbor of adult-born hippocampal neurons. (2010) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 107(17):7963-8. DOI: 10.1073/pnas.0914613107

Gage, F.H. Molecular and cellular mechanisms contributing to the regulation, proliferation and differentiation of neural stem cells in the adult dentate gyrus. (2010) Keio J Med. 59(3):79-83.

Stiefel, K.M., Fellous, J.M., Thomas, P.J., Sejnowski, T.J. Intrinsic subthreshold oscillations extend the influence of inhibitory synaptic inputs on cortical pyramidal neurons. (2010) European Journal of Neuroscience. 31(6):1019-26. DOI: 10.1111/j.1460-9568.2010.07146.x

Bonanomi, D., Pfaff, S.L. Motor axon pathfinding. (2010) Cold Spring Harbor Perspectives in Biology. 2(3):a001735. DOI: 10.1101/cshperspect.a001735

Moldakarimov, S., Bazhenov, M., Sejnowski, T.J. Perceptual priming leads to reduction of gamma frequency oscillations. (2010) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 107(12):5640-5645. DOI: 10.1073/pnas.0907525107

Drion, G., Bonjean, M., Waroux, O., Scuvée-Moreau, J., Liégeois, J.F., Sejnowski, T.J., Sepulchre, R., Seutin, V. M-type channels selectively control bursting in rat dopaminergic neurons. (2010) European Journal of Neuroscience. 31(5):827-835. DOI: 10.1111/j.1460-9568.2010.07107.x

Peterson, D.A., Sejnowski, T.J., Poizner, H. Convergent evidence for abnormal striatal synaptic plasticity in dystonia. (2010) Neurobiol. Dis. 37(3):558-73. DOI: 10.1016/j.nbd.2009.12.003

Glass, C.K., Saijo, K., Winner, B., Marchetto, M.C., Gage, F.H. Mechanisms underlying inflammation in neurodegeneration. (2010) Zelle. 140(6):918-34. DOI: 10.1016/j.cell.2010.02.016

Gage, F. The promise and the challenge of modelling human disease in a dish. (2010) EMBO Molecular Medicine. 2(3):77-8. DOI: 10.1002/emmm.201000060

Otte, S., Hasenstaub, A., Callaway, E.M. Cell type-specific control of neuronal responsiveness by gamma-band oscillatory inhibition. (2010) Journal of Neuroscience. 30(6):2150-2159. DOI: 10.1523/JNEUROSCI.4818-09.2010

Garcia-Campmany, L., Stam, F.J., Goulding, M. From circuits to behaviour: motor networks in vertebrates. (2010) Aktuelle Meinungen in der Neurobiologie. 20(1):116-25. DOI: 10.1016/j.conb.2010.01.002

Xu, X., Roby, K.D., Callaway, E.M. Immunochemical characterization of inhibitory mouse cortical neurons: three chemically distinct classes of inhibitory cells. (2010) Journal of Vergleichende Neurologie. 518(3):389-404. DOI: 10.1002/cne.22229

Lyon, D.C., Nassi, J.J., Callaway, E.M. A disynaptic relay from superior colliculus to dorsal stream visual cortex in macaque monkey. (2010) Neuron. 65(2):270-279. DOI: 10.1016/j.neuron.2010.01.003

Meyer, A., Gallarda, B.W., Pfaff, S., Alaynick, W. Spinal cord electrophysiology. (2010) J Vis Exp.(35) DOI: 10.3791/1660

Qu, Q., Sun, G., Li, W., Yang, S., Ye, P., Zhao, C., Yu, R.T., Gage, F.H., Evans, R.M., Shi, Y. Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. (2010) Nature Cell Biology. 12(1):31-40; sup pp 1-9. DOI: 10.1038/ncb2001