Waitt Advanced Biophotonics Center

Duan, B., Cheng, L., Bourane, S., Britz, O., Padilla, C., Garcia-Campmany, L., Krashes, M., Knowlton, W., Velasquez, T., Ren, X., Ross, S., Lowell, B.B., Wang, Y., Goulding, M., Ma, Q. Identification of spinal circuits transmitting and gating mechanical pain. (2014) Zelle. 159(6):1417-1432. DOI: 10.1016/j.cell.2014.11.003

Ritaccio, A., Brunner, P., Gunduz, A., Hermes, D., Hirsch, L.J., Jacobs, J., Kamada, K., Kastner, S., Knight, R.T., Lesser, R.P., Miller, K., Sejnowski, T., Worrell, G., Schalk, G. Proceedings of the Fifth International Workshop on Advances in Electrocorticography. (2014) Epilepsy Behav. 41:183-92. DOI: 10.1016/j.yebeh.2014.09.015

Calhoun, A.J., Chalasani, S.H., Sharpee, T.O. Maximally informative foraging by Caenorhabditis elegans. (2014) Elife. 3. DOI: 10.7554/eLife.04220

Pankevich, D.E., Altevogt, B.M., Dunlop, J., Gage, F.H., Hyman, S.E. Improving and accelerating drug development for nervous system disorders. (2014) Neuron. 84(3):546-53. DOI: 10.1016/j.neuron.2014.10.007

Regner, B.M., Tartakovsky, D.M., Sejnowski, T.J. Identifying transport behavior of single-molecule trajectories. (2014) Biophysical Journal. 107(10):2345-51. DOI: 10.1016/j.bpj.2014.10.005

Carcagno, A.L., Di Bella, D.J., Goulding, M., Guillemot, F., Lanuza, G.M. Neurogenin3 restricts serotonergic neuron differentiation to the hindbrain. (2014) Journal of Neuroscience. 34(46):15223-33. DOI: 10.1523/JNEUROSCI.3403-14.2014

Sejnowski, T.J., Churchland, P.S., Movshon, J.A. Putting big data to good use in neuroscience. (2014) Nature Neuroscience. 17(11):1440-1. DOI: 10.1038/nn.3839

Kim, S.H., Steele, J.W., Lee, S.W., Clemenson, G.D., Carter, T.A., Treuner, K., Gadient, R., Wedel, P., Glabe, C., Barlow, C., Ehrlich, M.E., Gage, F.H., Gandy, S. Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse. (2014) Molekulare Psychiatrie. 19(11):1235-42. DOI: 10.1038/mp.2014.87

Hook, V., Brennand, K.J., Kim, Y., Toneff, T., Funkelstein, L., Lee, K.C., Ziegler, M., Gage, F.H. Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons. (2014) Stem Cell Reports. 3(4):531-8. DOI: 10.1016/j.stemcr.2014.08.001

Aimone, J.B., Li, Y., Lee, S.W., Clemenson, G.D., Deng, W., Gage, F.H. Regulation and function of adult neurogenesis: from genes to cognition. (2014) Physiological Reviews. 94(4):991-1026. DOI: 10.1152/physrev.00004.2014

Jessberger, S., Gage, F.H. Adult neurogenesis: bridging the gap between mice and humans. (2014) Trends in der Zellbiologie. 24(10):558-63. DOI: 10.1016/j.tcb.2014.07.003

Fields, R.D., Araque, A., Johansen-Berg, H., Lim, S.S., Lynch, G., Nave, K.A., Nedergaard, M., Perez, R., Sejnowski, T., Wake, H. Glial biology in learning and cognition. (2014) The Neuroscientist. 20(5):426-431. DOI: 10.1177/1073858413504465

Mak-McCully, R.A., Deiss, S.R., Rosen, B.Q., Jung, K.Y., Sejnowski, T.J., Bastuji, H., Rey, M., Cash, S.S., Bazhenov, M., Halgren, E. Synchronization of isolated downstates (K-complexes) may be caused by cortically-induced disruption of thalamic spindling. (2014) PLOS Computational Biology. 10(9):e1003855. DOI: 10.1371/journal.pcbi.1003855

Stefan, M.I., Bartol, T.M., Sejnowski, T.J., Kennedy, M.B. Multi-state modeling of biomolecules. (2014) PLOS Computational Biology. 10(9):e1003844. DOI: 10.1371/journal.pcbi.1003844

Sharpee, T.O. Toward functional classification of neuronal types. (2014) Neuron. 83(6):1329-34. DOI: 10.1016/j.neuron.2014.08.040

Garrett, M.E., Nauhaus, I., Marshel, J.H., Callaway, E.M. Topography and areal organization of mouse visual cortex. (2014) Journal of Neuroscience. 34(37):12587-12600. DOI: 10.1523/JNEUROSCI.1124-14.2014

Winner, B., Marchetto, M.C., Winkler, J., Gage, F.H. Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease. (2014) Human Molecular Genetics. 23(R1):R27-34. DOI: 10.1093/hmg/ddu205

Gage, F., Nair, P. QnAs with Fred Gage. (2014) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 111(36):12958-9. DOI: 10.1073/pnas.1412625111

Moldakarimov, S., Bazhenov, M., Sejnowski, T.J. Top-down inputs enhance orientation selectivity in neurons of the primary visual cortex during perceptual learning. (2014) PLOS Computational Biology. 10(8):e1003770. DOI: 10.1371/journal.pcbi.1003770

Lee, H.S., Ghetti, A., Pinto-Duarte, A., Wang, X., Dziewczapolski, G., Galimi, F., Huitron-Resendiz, S., Piña-Crespo, J.C., Roberts, A.J., Verma, I.M., Sejnowski, T.J., Heinemann, S.F. Astrocytes contribute to gamma oscillations and recognition memory. (2014) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 111(32):E3343-52. DOI: 10.1073/pnas.1410893111

Erwin, J.A., Marchetto, M.C., Gage, F.H. Mobile DNA elements in the generation of diversity and complexity in the brain. (2014) Nature Reviews Neuroscience. 15(8):497-506. DOI: 10.1038/nrn3730

Gage, F., Pariente, N. On jumping genes and other things: Interview with Fred Gage, Adler Professor at the Salk Institute. (2014) EMBO Reports. 15(8):822-6. DOI: 10.15252/embr.201439088

Zhao, C., Jou, J., Wolff, L.J., Sun, H., Gage, F.H. Spine morphogenesis in newborn granule cells is differentially regulated in the outer and middle molecular layers. (2014) Journal of Vergleichende Neurologie. 522(12):2756-66. DOI: 10.1002/cne.23581

Weyhenmeyer, J., Hernandez, M.E., Lainscsek, C., Sejnowski, T.J., Poizner, H. Muscle artifacts in single trial EEG data distinguish patients with Parkinson's disease from healthy individuals. (2014) Conf Proc IEEE Eng Med Biol Soc. 2014:3292-3295. DOI: 10.1109/EMBC.2014.6944326

Broccard, F.D., Mullen, T., Chi, Y.M., Peterson, D., Iversen, J.R., Arnold, M., Kreutz-Delgado, K., Jung, T.P., Makeig, S., Poizner, H., Sejnowski, T., Cauwenberghs, G. Closed-loop brain-machine-body interfaces for noninvasive rehabilitation of movement disorders. (2014) Ann Biomed Eng. 42(8):1573-1593. DOI: 10.1007/s10439-014-1032-6

Bekinschtein, P., Kent, B.A., Oomen, C.A., Clemenson, G.D., Gage, F.H., Saksida, L.M., Bussey, T.J. Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories. (2014) Hippocampus. 24(8):905-11. DOI: 10.1002/hipo.22304

Hatori, M., Gill, S., Mure, L.S., Goulding, M., O'Leary, D.D., Panda, S. Lhx1 maintains synchrony among circadian oscillator neurons of the SCN. (2014) Elife. 3:e03357. DOI: 10.7554/eLife.03357

Ni, Y., Nawabi, H., Liu, X., Yang, L., Miyamichi, K., Tedeschi, A., Xu, B., Wall, N.R., Callaway, E.M., He, Z. Characterization of long descending premotor propriospinal neurons in the spinal cord. (2014) Journal of Neuroscience. 34(28):9404-9417. DOI: 10.1523/JNEUROSCI.1771-14.2014

Stein, J.L., de la Torre-Ubieta, L., Tian, Y., Parikshak, N.N., Hernández, I.A., Marchetto, M.C., Baker, D.K., Lu, D., Hinman, C.R., Lowe, J.K., Wexler, E.M., Muotri, A.R., Gage, F.H., Kosik, K.S., Geschwind, D.H. A quantitative framework to evaluate modeling of cortical development by neural stem cells. (2014) Neuron. 83(1):69-86. DOI: 10.1016/j.neuron.2014.05.035

Saremi, S., Sejnowski, T.J. On criticality in high-dimensional data. (2014) Neural Computation. 26(7):1329-1339. DOI: 10.1162/NECO_a_00607

Yu, D.X., Marchetto, M.C., Gage, F.H. How to make a hippocampal dentate gyrus granule neuron. (2014) Entwicklung. 141(12):2366-75. DOI: 10.1242/dev.096776

Solstad, T., Yousif, H.N., Sejnowski, T.J. Place cell rate remapping by CA3 recurrent collaterals. (2014) PLOS Computational Biology. 10(6):e1003648. DOI: 10.1371/journal.pcbi.1003648

Sharpee, T.O. Function determines structure in complex neural networks. (2014) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 111(23):8327-8. DOI: 10.1073/pnas.1407198111

Goulding, M., Bourane, S., Garcia-Campmany, L., Dalet, A., Koch, S. Inhibition downunder: an update from the spinal cord. (2014) Aktuelle Meinungen in der Neurobiologie. 26:161-6. DOI: 10.1016/j.conb.2014.03.006

Lacar, B., Parylak, S.L., Vadodaria, K.C., Sarkar, A., Gage, F.H. Increasing the resolution of the adult neurogenesis picture. (2014) F1000 Prime Reports. 6:8. DOI: 10.12703/P6-8

Hrvoj-Mihic, B., Marchetto, M.C., Gage, F.H., Semendeferi, K., Muotri, A.R. Novel tools, classic techniques: evolutionary studies using primate pluripotent stem cells. (2014) Biological Psychiatry. 75(12):929-35. DOI: 10.1016/j.biopsych.2013.08.007

Sejnowski, T.J. Summary: Cognition in 2014. (2014) Cold Spring Harbor Symposia für Quantitative Biologie. 79:237-41. DOI: 10.1101/sqb.2014.79.024885

Sejnowski, T.J., Poizner, H., Lynch, G., Gepshtein, S., Greenspan, R.J. Prospective Optimization. (2014) Proceedings of the IEEE. Institute of Electrical and Electronics Engineers. 102(5). DOI: 10.1109/JPROC.2014.2314297

Knowland, D., Arac, A., Sekiguchi, K.J., Hsu, M., Lutz, S.E., Perrino, J., Steinberg, G.K., Barres, B.A., Nimmerjahn, A., Agalliu, D. Stepwise recruitment of transcellular and paracellular pathways underlies blood-brain barrier breakdown in stroke. (2014) Neuron. 82(3):603-17. DOI: 10.1016/j.neuron.2014.03.003

Jadi, M.P., Sejnowski, T.J. Cortical oscillations arise from contextual interactions that regulate sparse coding. (2014) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 111(18):6780-5. DOI: 10.1073/pnas.1405300111

Hashimoto-Torii, K., Torii, M., Fujimoto, M., Nakai, A., El Fatimy, R., Mezger, V., Ju, M.J., Ishii, S., Chao, S.H., Brennand, K.J., Gage, F.H., Rakic, P. Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders. (2014) Neuron. 82(3):560-72. DOI: 10.1016/j.neuron.2014.03.002

Cetin, A., Callaway, E.M. Optical control of retrogradely infected neurons using drug-regulated "TLoop" lentiviral vectors. (2014) Journal für Neurophysiologie. 111(10):2150-2159. DOI: 10.1152/jn.00495.2013

Wang, L., Mongera, A., Bonanomi, D., Cyganek, L., Pfaff, S.L., Nüsslein-Volhard, C., Marquardt, T. A conserved axon type hierarchy governing peripheral nerve assembly. (2014) Entwicklung. 141(9):1875-83. DOI: 10.1242/dev.106211

McDonnell, M.D., Boahen, K., Ijspeert, A., Sejnowski, T.J. Engineering Intelligent Electronic Systems Based on Computational Neuroscience. (2014) Proceedings of the IEEE. Institute of Electrical and Electronics Engineers. 102(5):646-651. DOI: 10.1109/JPROC.2014.2314776

Rockenstein, E., Nuber, S., Overk, C.R., Ubhi, K., Mante, M., Patrick, C., Adame, A., Trejo-Morales, M., Gerez, J., Picotti, P., Jensen, P.H., Campioni, S., Riek, R., Winkler, J., Gage, F.H., Winner, B., Masliah, E. Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo. (2014) Brain. 137(Pt 5):1496-513. DOI: 10.1093/brain/awu057

Havlicek, S., Kohl, Z., Mishra, H.K., Prots, I., Eberhardt, E., Denguir, N., Wend, H., Plötz, S., Boyer, L., Marchetto, M.C., Aigner, S., Sticht, H., Groemer, T.W., Hehr, U., Lampert, A., Schlötzer-Schrehardt, U., Winkler, J., Gage, F.H., Winner, B. Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons. (2014) Human Molecular Genetics. 23(10):2527-41. DOI: 10.1093/hmg/ddt644

Jadi, M.P., Sejnowski, T.J. Regulating Cortical Oscillations in an Inhibition-Stabilized Network. (2014) Proceedings of the IEEE. Institute of Electrical and Electronics Engineers. 102(5). DOI: 10.1109/JPROC.2014.2313113

O'Donnell, C., Sejnowski, T.J. Selective memory generalization by spatial patterning of protein synthesis. (2014) Neuron. 82(2):398-412. DOI: 10.1016/j.neuron.2014.02.028

Sharpee, T.O., Calhoun, A.J., Chalasani, S.H. Information theory of adaptation in neurons, behavior, and mood. (2014) Aktuelle Meinungen in der Neurobiologie. 25:47-53. DOI: 10.1016/j.conb.2013.11.007

Morris, R., Sancho-Martinez, I., Sharpee, T.O., Izpisua Belmonte, J.C. Mathematical approaches to modeling development and reprogramming. (2014) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 111(14):5076-82. DOI: 10.1073/pnas.1317150111

Firth, A.L., Dargitz, C.T., Qualls, S.J., Menon, T., Wright, R., Singer, O., Gage, F.H., Khanna, A., Verma, I.M. Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells. (2014) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 111(17):E1723-30. DOI: 10.1073/pnas.1403470111

Zhang, J., Lanuza, G.M., Britz, O., Wang, Z., Siembab, V.C., Zhang, Y., Velasquez, T., Alvarez, F.J., Frank, E., Goulding, M. V1 and v2b interneurons secure the alternating flexor-extensor motor activity mice require for limbed locomotion. (2014) Neuron. 82(1):138-50. DOI: 10.1016/j.neuron.2014.02.013

Sun, Y., Nguyen, A.Q., Nguyen, J.P., Le, L., Saur, D., Choi, J., Callaway, E.M., Xu, X. Cell-type-specific circuit connectivity of hippocampal CA1 revealed through Cre-dependent rabies tracing. (2014) Cell Reports. 7(1):269-280. DOI: 10.1016/j.celrep.2014.02.030

Pao, G.M., Zhu, Q., Perez-Garcia, C.G., Chou, S.J., Suh, H., Gage, F.H., O'Leary, D.D., Verma, I.M. Role of BRCA1 in brain development. (2014) Verhandlungen der Nationalen Akademie der Wissenschaften der Vereinigten Staaten von Amerika. 111(13):E1240-8. DOI: 10.1073/pnas.1400783111

Levine, A.J., Hinckley, C.A., Hilde, K.L., Driscoll, S.P., Poon, T.H., Montgomery, J.M., Pfaff, S.L. Identification of a cellular node for motor control pathways. (2014) Nature Neuroscience. 17(4):586-93. DOI: 10.1038/nn.3675

Crotti, A., Benner, C., Kerman, B.E., Gosselin, D., Lagier-Tourenne, C., Zuccato, C., Cattaneo, E., Gage, F.H., Cleveland, D.W., Glass, C.K. Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors. (2014) Nature Neuroscience. 17(4):513-21. DOI: 10.1038/nn.3668

Edwards, J., Daniel, E., Kinney, J., Bartol, T., Sejnowski, T., Johnston, D., Harris, K., Bajaj, C. VolRoverN: enhancing surface and volumetric reconstruction for realistic dynamical simulation of cellular and subcellular function. (2014) Neuroinformatics. 12(2):277-289. DOI: 10.1007/s12021-013-9205-2

Yu, D.X., Di Giorgio, F.P., Yao, J., Marchetto, M.C., Brennand, K., Wright, R., Mei, A., McHenry, L., Lisuk, D., Grasmick, J.M., Silberman, P., Silberman, G., Jappelli, R., Gage, F.H. Modeling hippocampal neurogenesis using human pluripotent stem cells. (2014) Stem Cell Reports. 2(3):295-310. DOI: 10.1016/j.stemcr.2014.01.009

Cruz-Martín, A., El-Danaf, R.N., Osakada, F., Sriram, B., Dhande, O.S., Nguyen, P.L., Callaway, E.M., Ghosh, A., Huberman, A.D. A dedicated circuit links direction-selective retinal ganglion cells to the primary visual cortex. (2014) Natur. 507(7492):358-361. DOI: 10.1038/nature12989

Wright, R., Réthelyi, J.M., Gage, F.H. Enhancing induced pluripotent stem cell models of schizophrenia. (2014) JAMA Psychiatry. 71(3):334-5. DOI: 10.1001/jamapsychiatry.2013.4239

Yang, L., Leung, H., Peterson, D.A., Sejnowski, T.J., Poizner, H. Toward a semi-self-paced EEG brain computer interface: decoding initiation state from non-initiation state in dedicated time slots. (2014) PLOS One. 9(2):e88915. DOI: 10.1371/journal.pone.0088915

Vadodaria, K.C., Gage, F.H. SnapShot: adult hippocampal neurogenesis. (2014) Zelle. 156(5):1114-1114.e1. DOI: 10.1016/j.cell.2014.02.029

Rangel, L.M., Alexander, A.S., Aimone, J.B., Wiles, J., Gage, F.H., Chiba, A.A., Quinn, L.K. Temporally selective contextual encoding in the dentate gyrus of the hippocampus. (2014) Nature Communications. 5:3181. DOI: 10.1038/ncomms4181

Parylak, S.L., Deng, W., Gage, F.H. Mother's milk programs offspring's cognition. (2014) Nature Neuroscience. 17(1):8-9. DOI: 10.1038/nn.3611

Marchetto, M.C., Gage, F.H. Your brain under the microscope: the promise of stem cells. (2014) Cerebrum. 2014:1.