Vicki Lundblad

Professor

Molecular and Cell Biology Laboratory

Becky and Ralph S. O'Connor Chair

Salk Institute for Biological Studies - Publications

Publications


Johnathan W. Lubin, Timothy M. Tucey and Victoria Lundblad (2017). Using Separation-of-Function Mutagenesis To Define the Full Spectrum of Activities Performed by the Est1 Telomerase Subunit in Vivo. Genetics, 207.

Rao, T., Lubin, J., Armstrong, G.S., Tucey T.M., Lundblad, V. and Wuttke, D.S. (2014). Structure of Est3 reveals a bimodal surface with differential roles in telomere replication. PNAS, 111, 214-218.

Ballew, B.J. and Lundblad, V. (2013) Multiple genetic pathways regulate replicative senescence in telomerase-deficient yeast. Aging Cell, 12, 719-727.

Lubin, J., Rao, T., Mandell, E.K., Wuttke, D.S. and Lundblad, V. (2013) Dissecting protein function: an efficient protocol for identifying separation-of-function mutations that encode structurally stable proteins. Genetics, 193, 715-725.

Tucey T.M. and Lundblad, V. (2013). A yeast telomerase complex containing the Est1 recruitment protein is assembled early in the cell cycle. Biochemistry, 52, 1131-1133.

Lubin, J.W., Tucey, T.M. and Lundblad, V. (2012). The interaction between the yeast telomerase RNA and the Est1 protein requires three structural elements. RNA, 18, 1597-604.

Paschini, M., Toro, T.B, Lubin, J.W., Braunstein-Ballew, B., Morris, D.K. and Lundblad, V. (2012). A naturally thermolabile activity compromises genetic analysis of telomere function in Saccharomyces cerevisiae. Genetics, 191, 79-93.

Mandell, E.K., Gelinas, A.D., Wuttke, D.S. and Lundblad, V. (2011). Sequence-specific binding to telomeric DNA is not a conserved property of the Cdc13 DNA binding domain. Biochemistry, 50, 6289-6291.

Paschini, M., Mandell, E.K. and Lundblad, V. (2010). Structure prediction-driven genetics in Saccharomyces cerevisiae identifies an interface between the t-RPA proteins Stn1 and Ten1. Genetics, 185, 11-21.

Lee, J.S., Mandell, E.K., Rao, T., Wuttke, D.S. and Lundblad, V. (2010). Investigating the role of the Est3 protein in yeast telomere replication. Nucleic Acids Res., 38, 2279-2290.

Gao, H., Toro, T.B., Paschini, M., Braunstein-Ballew, B., Cervantes, R.B. and Lundblad, V. (2010). Telomerase recruitment in Saccharomyces cerevisiae is not dependent on Tel1-mediated phosphorylation of Cdc13. Genetics 186, 1147-1159.

Gelinas, A.D., Paschini, M., Reyes, F.E., Héroux, A., Batey, R.T., Lundblad, V., and Wuttke, D.S. (2009). The telomere capping proteins Stn1 and Ten1 are structurally related to RPA32 and RPA14. PNAS 106, 19298-19303.

Lee, J.S., Mandell, E.K., Tucey T.M. Morris, D.K. and Lundblad, V. (2008). The Est3 protein associates with yeast telomerase through an OB-fold domain. Nature Struct. & Mol. Biol. 15, 990-997.

Gao, H., Cervantes, R.B., Mandell, E.K., Otero, J., and Lundblad, V. (2007). RPA-like proteins mediate yeast telomere function. Nature Struct. & Mol. Biol. 14, 208-214.

Education

BS, University of California, Berkeley
PhD, Harvard University
Postdoctoral Fellow, Harvard Medical School and UC Berkeley


Awards & Honors

  • 2015 National Academy of Sciences
  • 2014 Fellow of the American Academy for Microbiology
  • 2008 Pearl Meister Greengard Prize
  • 2003 Fellow of the American Association for the Advancement of Science
  • 2002 NIH MERIT award, National Institute on Aging
  • 2002 AACR-NFCR Professorship in Basic Cancer Research
  • 2001 Ellison Medical Foundation Senior Scholar in Aging Award
  • 1997 Michael E. DeBakey, M.D. Excellence in Research Award
  • 1994 American Cancer Society Junior Faculty Award

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