Videos

Laura Attardi - p53 Governs an AT1 Differentiation Program During Lung Adenocarcinoma Suppression

Adrian Vega-Perez - Rapid Generation of Precision Preclinical Cancer Models using Regulated In Vivo Base Editing

Katie Grausam - A Series of EGFR-mutant Models of Glioblastoma that Recapitulates Patient Tumor Heterogeneity and Response to Treatment

Lillian Eichner - HDAC3 is Critical in Tumor Development and Therapeutic Resistance in Kras-mutant Non-small Cell Lung Cancer

Alissandra Hillis - AKT Inhibition Synergizes with Mevalonate Pathway Disruption in TNBC

Howard Chang - Cancer Genes Beyond Chromosomes

Zhichao Xu - Recurrent 3D Genome Structural Alterations Facilitate Activity Dependent Oncogene Expression

Corina Antal - A Super-enhancer Regulated RNA-binding Protein Cascade Drives Pancreatic Cancer

Chris Vakoc - Tumor Lineage Plasticity Mechanisms Revealed by Genetic Screens

Matthew Maxwell - Loss of the ARID1A Tumor Suppressor Activates an R-loop Driven STING-Type I Interferon Signaling Axis that Promotes Anti-Tumor Immunity

Xueqian Zhuang - Aging-induced Epigenetic Reprogramming of the Cell of Origin Defines Lung Cancer Evolution

Amanda Lund - Lymphatic Transport and the Intratumoral T Cell Repertoire

Melissa Reeves - Spatial Heterogeneity of Tumor Cells Drives Intratumoral Organization of Immune Cells and Impedes Immunotherapy

Goran Micevic - Epigenetically Poised CD8+ T cells Marked by IL-7R are Critical for Antitumor Memory

Lydia Lynch - Innate T cells

Anna-Maria Globig - Adrenergic Receptors Regulate T Cell Differentiation in Viral Infection and Cancer

Martina Damo - PD-1 Safeguards Against Cutaneous Immunopathology by Local Neoantigen-specific CD8 T cells

Melissa Meyer - LIGHT Loss Enhances Response to Immunotherapy in Solid Tumors

Heather Christofk - Tumor Suppressor-Driven Metabolic Dependencies

Sam Kerk - Metabolic Reprogramming of Myeloid Cells in Pancreatic Cancer

Karl Wessendorf-Rodriguez - Modeling Sphingolipid Metabolism Using Stable Isotope Tracing

Matthew VanderHeiden (Massachusetts Institute of Technology) Influence of Metabolism on Cancer Progression

Mingqi Han - LKB1 Regulates Mitochondrial Networks and Bioenergetics Spatially and Temporally in Lung Cancer

Benjamin Stein - LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma

Jan Remsik for Adrienne Biore - Interferon-γ Mediates Reprogramming of Innate Anti-tumor Immunity in the Leptomeninges

Ruth Palmer - ALK Signaling Primes the DNA Damage Response Allowing Exploitation of ATR Inhibition in ALK-driven Neuroblastoma

Florian Karreth - Control of PHGDH Expression by a MAPK/ATF4 Axis Establishes a Metabolic Vulnerability in Melanoma

Hannah Carter - Common Germline Variation Modulates Anti-tumor Immunity

Erik Bergstrom - Mapping Clustered Mutations in Cancer Reveals APOBEC3 Mutagenesis of ecDNA

Benjamin Spike - Cellular Crosstalk and Stress-Adaptive Plasticity: Deciphering CRIPTO’s Role in Triple Negative Breast Cancer