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Gage Lab Symposium

Program

Salk Institute for Biological Studies - Gage Lab Symposium - Program

Gage Lab Symposium – Program

Day 1: Thursday, November 13

     
Time Title Speaker Location
8:30 a.m. Registration – Continental breakfast available Patio, Roth Auditorium
9:05 a.m. Welcoming remarks, Session 1 Rusty Gage, Chair All talks in the Roth Auditorium
9:15 a.m. Engineering brain organoids for modeling neurodevelopment and diseases Guo-li Ming
9:35 a.m. Scaling up functional drug screens with iPSC models for pediatric neurodegenerative diseases Cedric Bardy
9:55 a.m. Using stem cells to explore the genetics underlying brain disease Kristen Brennand
10:55 a.m. 30 min. Break
10:45 a.m. Brain mosaicism in pediatric epilepsies Tracy Bedrosian
11:05 a.m. Connectome of human glioblastoma Hongjun Song
11:25 a.m. Brain-wide contribution of adult-born neurons Juan Song
11:45 a.m. Lunch
1:15 p.m. Session 2 Guo-li Ming, Chair
1:15 p.m. Mapping the landscape of DNA:RNA hybrids in the aging mammalian nervous system Dylan Reid
1:35 p.m. Long-lived RNAs in mammalian brain cells Tomohisa Toda
1:55 p.m. Recombinant adeno-associated virus (AAV) depletes PARP1 and other DNA damage Matthew Shtrahman
2:15 p.m. An SVA retrotransposon’s contribution to neurodegeneration Jennifer Erwin
2:35 p.m. 30 min. Break
3:05 p.m. Session 3 Dylan Reid, Chair
3:05 p.m. Lifelong natural variations in hippocampus neurogenesis Nico Toni
3:25 p.m. Functions of adult neurogenesis in the human brain Michael Bonagudi
3:45 p.m. Overexpression of OTX2 in human neural cells links depression risk genes Cathy Barr
4:05 p.m. Poster session, photo op, happy hour SCRM Lobby
6:00 p.m. Dinner SCRM Patio

Day 2: Friday, November 14

Time Title Speaker Time
8:30 a.m. Continental breakfast available Patio, Roth Auditorium
9:05 a.m. Session 4 Nico Toni, Chair All talks in the Roth Auditorium
9:05 a.m. Unlocking AUTS2 multifaceted role in neurodevelopment Carol Marchetto
9:25 a.m. Bridging disorders: Insights into epilepsy and Alzheimer’s through brain organoid models Jenny Hsieh
9:45 a.m. Sex-based network connectivity shapes cognitive function in XX and XY neuronal models Shani Stern
10:05 a.m. Studying the collective dynamics of human iPSC-derived neuronal population activity Krishan Padmanabhan
10:25 a.m. 30 min. Break
10:55 a.m. Session 5 Carol Marchetto, Chair
10:55 a.m. New approaches to decode human microglia phenotypes in health and disease Simon Schafer
11:15 a.m. Reprogramming the resident glial cells Chun-Li Zhang
11:35 a.m. From new neurons to new chips: How neuromorphic computing can help us understand the brain Brad Aimone
11:55 a.m. Multimodal approaches to interrogate critical genes for brain development and autism Xinyu Zhao
12:15 p.m. Lunch Bella Vista
1:25 p.m. Session 6 Simon Schafer, Chair All talks in the Roth Auditorium
1:25 p.m. TNF-α hijacks metabolism in Parkinson’s gut neurons Beate Winner
1:45 p.m. Hypoxia gradients organize glioblastoma along a neurodevelopmental axis Yusha Sun
2:05 p.m. Creating a targetable and switchable vector system for cell lineage specification Daniel Peterson
2:25 p.m. Regulation of neural development: Hippo pathway and beyond Xinwei Cao
2:45 p.m. 30 min. Break
3:15 p.m. Session 7 Beate Winner, Chair
3:15 p.m. Hippocampal progenitor cells as biomarkers of cognitive ageing and dementia Sandrine Thuret
3:35 p.m. Deubiquitinases (DUBs) and neurodegeneration: A new frontier in therapeutic development Mohamedi Kagalwala
3:55 p.m. Directed evolution of novel AAV variants for clinical gene therapy David Schaffer
4:15 p.m. Translational neuroscience Mark Tuszynski
4:35 p.m. Closing remarks Rusty Gage
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