Page Tools

Faculty

Greg E. Lemke

Greg E. Lemke

Professor
Molecular Neurobiology Laboratory

Our laboratory is interested in the signal transduction molecules that mediate cellular interactions during development of the mammalian nervous and immune system. We employ several experimental models, most of them in the mouse, which exploit both cell culture and molecular genetics.

Over the last several years, we have focused in particular on three receptor protein-tyrosine kinase signaling systems: the ErbB receptors and their ligands of the neuregulin family, the Eph receptors and their ephrin ligands, and the Tyro 3 family receptors and their ligands Gas6 and protein S. We have investigated the roles that these proteins play in neural and immune development by engineering and then analyzing knock-out and knock-in mutations in their corresponding genes in the chick and mouse.

Education

Awards and Honors

Selected Publications

Salk News Releases