健康老龄化

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Salk Institute for Biological Studies - Healthy Aging - Videos

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限时进食改善消防员健康

拉霍亚—消防员是我们社会的英雄,全天候保护着我们。但这些 24 小时的轮班工作对身体非常不利,并且会增加患心脏代谢疾病(如心脏病和糖尿病)以及癌症的风险。圣地亚哥消防局与索尔克研究所和加州大学圣地亚哥分校健康中心的科学家合作进行的一项临床试验发现,限时进食可以改善消防员的健康和福祉指标。这种生活方式干预措施仅要求消防员在 10 小时的时间窗口内进食,并且不涉及跳餐。. 阅读更多 »


细胞重编程疗法可安全逆转小鼠的衰老迹象

LA JOLLA—Age may be just a number, but it’s a number that often carries unwanted side effects, from brittle bones and weaker muscles to increased risks of cardiovascular disease and cancer. Now, scientists at the Salk Institute, in collaboration with Genentech, a member of the Roche group, have shown that they can safely and effectively reverse the aging process in middle-aged and elderly mice by partially resetting their cells to more youthful states. 阅读更多 »


Chimeric tool advanced for wide range of regenerative medicine, biomedical research applications

LA JOLLA—The ability to grow the cells of one species within an organism of a different species offers scientists a powerful tool for research and medicine. It’s an approach that could advance our understanding of early human development, disease onset and progression and aging; provide innovative platforms for drug evaluation; and address the critical need for transplantable organs. Yet developing such capabilities has been a formidable challenge. 阅读更多 »


The science of aging


首个可逃避免疫的细胞疗法获批用于治疗1型糖尿病

拉霍亚—索尔克研究所的科学家们在追求安全有效的I型糖尿病治疗方法方面取得了重大进展。I型糖尿病影响着美国约160万人口,每年造成的经济损失高达$144亿美元。.

利用干细胞技术,索尔克研究所的研究人员生成了首批能够逃避免疫系统的人类胰岛素生成胰腺细胞簇,相关细节发表在该期刊上 自然 2020年8月19日。这些“免疫屏蔽”的细胞簇一经移植到体内,就能在不使用免疫抑制药物的情况下控制小鼠的血糖。. 阅读更多 »