韦特先进生物光子学中心

研究

Salk Institute for Biological Studies - Waitt Advanced Biophotonics Center - Research

2021 PUBLICATIONS


所有出版物


Gage, F.H. Adult neurogenesis in neurological diseases. [Pubmed] (2021) 科学. 374(6571):1049-1050. DOI: 10.1126/science.abm7468

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Heard, K.J., Shokhirev, M.N., Becronis, C., Fredlender, C., Zahid, N., Le, A.T., Ji, Y., Skime, M., Nelson, T., Hall-Flavin, D., Weinshilboum, R., Gage, F.H., Vadodaria, K.C. Chronic cortisol differentially impacts stem cell-derived astrocytes from major depressive disorder patients. (2021) Transl Psychiatry. 11(1):608. DOI: 10.1038/s41398-021-01733-9

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Wagner, M., Bartol, T.M., Sejnowski, T.J., Cauwenberghs, G. 用于神经形态计算的突触传递电化学反应-扩散的马尔可夫链抽象。. (2021) 神经科学前沿. 15:698635。DOI:10.3389/fnins.2021.698635

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Mendelsohn, R., Garcia, G.C., Bartol, T.M., Lee, C.T., Khandelwal, P., Liu, E., Spencer, D.J., Husar, A., Bushong, E.A., Phan, S., Perkins, G., Ellisman, M.H., Skupin, A., Sejnowski, T.J., Rangamani, P. 神经元线粒体的形态学原理。. (2021) 神经科学杂志. 10.1002/cne.25254

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Liu, H., Zhou, J., Tian, W., Luo, C., Bartlett, A., Aldridge, A., Lucero, J., Osteen, J.K., Nery, J.R., Chen, H., Rivkin, A., Castanon, R.G., Clock, B., Li, Y.E., Hou, X., Poirion, O.B., Preissl, S., Pinto-Duarte, A., O'Connor, C., Boggeman, L., Fitzpatrick, C., Nunn, M., Mukamel, E.A., Zhang, Z., Callaway, E.M., Ren, B., Dixon, J.R., Behrens, M.M., Ecker, J.R. DNA methylation atlas of the mouse brain at single-cell resolution. (2021) 自然. 598(7879):120-128. DOI: 10.1038/s41586-020-03182-8

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Zhang, Z., Zhou, J., Tan, P., Pang, Y., Rivkin, A.C., Kirchgessner, M.A., Williams, E., Lee, C.T., Liu, H., Franklin, A.D., Miyazaki, P.A., Bartlett, A., Aldridge, A.I., Vu, M., Boggeman, L., Fitzpatrick, C., Nery, J.R., Castanon, R.G., Rashid, M., Jacobs, M.W., Ito-Cole, T., O'Connor, C., Pinto-Duartec, A., Dominguez, B., Smith, J.B., Niu, S.Y., Lee, K.F., Jin, X., Mukamel, E.A., Behrens, M.M., Ecker, J.R., Callaway, E.M. Epigenomic diversity of cortical projection neurons in the mouse brain. (2021) 自然. 598(7879):167-173. DOI: 10.1038/s41586-021-03223-w

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Davis, Z.W., Benigno, G.B., Fletterman, C., Desbordes, T., Steward, C., Sejnowski, T.J., Reynolds, J.H., Muller, L. 自发传播的行波由于水平纤维的时延而自然出现,并穿过局部异步不规则状态。. (2021) 自然-通讯. 12(1):6057。DOI: 10.1038/s41467-021-26175-1

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Li, Y., Kim, R., Sejnowski, T.J. 在脉冲神经网络模型中学习作用于工作记忆的突触和内在膜动力学。. (2021) 神经计算.:1-24 DOI: 10.1162/neco_a_01409

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Lainscsek, C., Cash, S.S., Sejnowski, T.J., Kurths, J. 动力学遍历性DDA揭示时间序列中的因果结构。. (2021) 混乱. 31(10):103108。DOI:10.1063/5.0063724

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Kirchgessner, M.A., Franklin, A.D., Callaway, E.M. Distinct "driving" versus "modulatory" influences of different visual corticothalamic pathways. (2021) 当前生物学。. DOI: 10.1016/j.cub.2021.09.025

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Gorbunova, V., Seluanov, A., Mita, P., McKerrow, W., Fenyö, D., Boeke, J.D., Linker, S.B., Gage, F.H., Kreiling, J.A., Petrashen, A.P., Woodham, T.A., Taylor, J.R., Helfand, S.L., Sedivy, J.M. The role of retrotransposable elements in ageing and age-associated diseases. https://rdcu.be/ct1i3 Full-text provided by the Springer Nature SharedIt content-sharing initiative [Pubmed] (2021) 自然. 596(7870):43-53. DOI: 10.1038/s41586-021-03542-y

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Shadel, G.S., Adams, P.D., Berggren, W.T., Diedrich, J.K., Diffenderfer, K.E., Gage, F.H., Hah, N., Hansen, M., Hetzer, M.W., Molina, A.J.A., Manor, U., Marek, K., O'Keefe, D.D., Pinto, A.F.M., Sacco, A., Sharpee, T.O., Shokriev, M.N., Zambetti, S. The San Diego Nathan Shock Center: tackling the heterogeneity of aging. (2021) Geroscience. DOI: 10.1007/s11357-021-00426-x

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Amin, N.D., Senturk, G., Costaguta, G., Driscoll, S., O'Leary, B., Bonanomi, D., Pfaff, S.L. A hidden threshold in motor neuron gene networks revealed by modulation of miR-218 dose. (2021) 神经元. DOI: 10.1016/j.neuron.2021.07.028

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Hayes, T.L., Krishnan, G.P., Bazhenov, M., Siegelmann, H.T., Sejnowski, T.J., Kanan, C. 深度学习中的重放:当前方法及缺失的生物学元素. (2021) 神经计算.:1-44 DOI: 10.1162/neco_a_01433

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Johnston, S., Parylak, S., Kim, S., Mac, N., Lim, C., Gallina, I., Bloyd, C., Newberry, A., Saavedra, C.D., Novak, O., Goncalves, J.T., Gage, F.H., Shtrahman, M. AAV ablates neurogenesis in the adult murine hippocampus. (2021) Elife. 10. DOI: 10.7554/eLife.59291

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Nakahira, Y., Liu, Q., Sejnowski, T.J., Doyle, J.C. 分层架构中支持多样性的最佳区域及感觉运动控制中的速度-准确性权衡。. (2021) 美国国家科学院院刊. 118(22). DOI: 10.1073/pnas.1916367118

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Tan, K., Kim, M.E., Song, H.W., Skarbrevik, D., Babajanian, E., Bedrosian, T.A., Gage, F.H., Wilkinson, M.F. The Rhox gene cluster suppresses germline LINE1 transposition. (2021) 美国国家科学院院刊. 118(23). DOI: 10.1073/pnas.2024785118

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Faulkner, R.L., Wall, N.R., Callaway, E.M., Cline, H.T. Application of Recombinant Rabies Virus to Xenopus Tadpole Brain. (2021) eNeuro. DOI: 10.1523/ENEURO.0477-20.2021

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Schafer, S.T., Gage, F.H. To eat, or not to eat, that is the question: Neural stem cells escape phagocytosis in autism with macrocephaly. (2021) 美国国家科学院院刊. 118(19). DOI: 10.1073/pnas.2104888118


Compans, B., Camus, C., Kallergi, E., Sposini, S., Martineau, M., Butler, C., Kechkar, A., Klaassen, R.V., Retailleau, N., Sejnowski, T.J., Smit, A.B., Sibarita, J.B., Bartol, T.M., Perrais, D., Nikoletopoulou, V., Choquet, D., Hosy, E. NMDAR依赖的长时程抑制与通过自噬介导的PSD-95丢失所致的短期可塑性增强有关。. (2021) 自然-通讯. 12(1):2849. DOI: 10.1038/s41467-021-23133-9

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Dias, G.P., Murphy, T., Stangl, D., Ahmet, S., Morisse, B., Nix, A., Aimone, L.J., Aimone, J.B., Kuro-O, M., Gage, F.H., Thuret, S. Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis, and expression of longevity gene Klotho. (2021) Molecular Psychiatry. DOI: 10.1038/s41380-021-01102-4

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Hsu, W.M., Kastner, D.B., Baccus, S.A., Sharpee, T.O. How inhibitory neurons increase information transmission under threshold modulation. (2021) 细胞报告. 35(8):109158. DOI: 10.1016/j.celrep.2021.109158

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Reid, D.A., Reed, P.J., Schlachetzki, J.C.M., Nitulescu, I.I., Chou, G., Tsui, Chandran, S., Jones, J.R., Lu, A.T., McClain, C.A., Ooi, J.H., Wang, T.W., Lana, Linker, S.B., Ricciardulli, A.S., Lau, S., Schafer, S., Horvath, S., Dixon, J.R., Hah, N., Glass, C.K., Gage, F.H. Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons. (2021) 科学. 372(6537):91-94. DOI: 10.1126/science.abb9032

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Huang, Y., Happonen, K.E., Burrola, P.G., O'Connor, C., Hah, N., Huang, L., Nimmerjahn, A., Lemke, G. Microglia use TAM receptors to detect and engulf amyloid β plaques. (2021) Nature Immunology. DOI: 10.1038/s41590-021-00913-5

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Osseward, P.J., Amin, N.D., Moore, J.D., Temple, B.A., Barriga, B.K., Bachmann, L.C., Beltran, F., Gullo, M., Clark, R.C., Driscoll, S.P., Pfaff, S.L., Hayashi, M. Conserved genetic signatures parcellate cardinal spinal neuron classes into local and projection subsets. (2021) 科学. 372(6540):385-393. DOI: 10.1126/science.abe0690

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Mertens, J., Herdy, J.R., Traxler, L., Schafer, S.T., Schlachetzki, J.C.M., Böhnke, L., Reid, D.A., Lee, H., Zangwill, D., Fernandes, D.P., Agarwal, R.K., Lucciola, R., Zhou-Yang, L., Karbacher, L., Edenhofer, F., Stern, S., Horvath, S., Paquola, A.C.M., Glass, C.K., Yuan, S.H., Ku, M., Szücs, A., Goldstein, L.S.B., Galasko, D., Gage, F.H. Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients. (2021) 细胞干细胞. DOI: 10.1016/j.stem.2021.04.004

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Schafer, S.T., Gage, F.H. The When and Where: Molecular and Cellular Convergence in Autism. (2021) 生物精神病学. 89(5):419-420. DOI: 10.1016/j.biopsych.2020.12.016


Mishra, H.K., Ying, N.M., Luis, A., Wei, H., Nguyen, M., Nakhla, T., Vandenburgh, S., Alda, M., Berrettini, W.H., Brennand, K.J., Calabrese, J.R., Coryell, W.H., Frye, M.A., Gage, F.H., Gershon, E.S., McInnis, M.G., Nievergelt, C.M., Nurnberger, J.I., Shilling, P.D., Oedegaard, K.J., Zandi, P.P., , Kelsoe, J.R., Welsh, D.K., McCarthy, M.J. Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response: preliminary studies. (2021) Molecular Psychiatry. DOI: 10.1038/s41380-021-01048-7

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Zhou, Y., Sharpee, T.O. Hyperbolic geometry of gene expression. (2021) iScience. 24(3):102225. DOI: 10.1016/j.isci.2021.102225

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Nakatsuka, N., Heard, K.J., Faillétaz, A., Momotenko, D., Vörös, J., Gage, F.H., Vadodaria, K.C. Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes. (2021) Molecular Psychiatry. DOI: 10.1038/s41380-021-01066-5

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Bedrosian, T.A., Houtman, J., Eguiguren, J.S., Ghassemzadeh, S., Rund, N., Novaresi, N.M., Hu, L., Parylak, S.L., Denli, A.M., Randolph-Moore, L., Namba, T., Gage, F.H., Toda, T. Lamin B1 decline underlies age-related loss of adult hippocampal neurogenesis. (2021) EMBO 期刊. 40(3):e105819. DOI: 10.15252/embj.2020105819

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Fukuda, S., Varshney, A., Fowler, B.J., Wang, S.B., Narendran, S., Ambati, K., Yasuma, T., Magagnoli, J., Leung, H., Hirahara, S., Nagasaka, Y., Yasuma, R., Apicella, I., Pereira, F., Makin, R.D., Magner, E., Liu, X., Sun, J., Wang, M., Baker, K., Marion, K.M., Huang, X., Baghdasaryan, E., Ambati, M., Ambati, V.L., Pandey, A., Pandya, L., Cummings, T., Banerjee, D., Huang, P., Yerramothu, P., Tolstonog, G.V., Held, U., Erwin, J.A., Paquola, A.C.M., Herdy, J.R., Ogura, Y., Terasaki, H., Oshika, T., Darwish, S., Singh, R.K., Mozaffari, S., Bhattarai, D., Kim, K.B., Hardin, J.W., Bennett, C.L., Hinton, D.R., Hanson, T.E., Röver, C., Parang, K., Kerur, N., Liu, J., Werner, B.C., Sutton, S.S., Sadda, S.R., Schumann, G.G., Gelfand, B.D., Gage, F.H., Ambati, J. Cytoplasmic synthesis of endogenous complementary DNA via reverse transcription and implications in age-related macular degeneration. (2021) 美国国家科学院院刊. 118(6). DOI: 10.1073/pnas.2022751118

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Singh, N., Bartol, T., Levine, H., Sejnowski, T., Nadkarni, S. 突触前内质网调控海马突触的短期可塑性。. (2021) 传达生物学. 4(1):241. DOI: 10.1038/s42003-021-01761-7

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Vadodaria, K.C., Mendes, A.P.D., Mei, A., Racha, V., Erikson, G., Shokhirev, M.N., Oefner, R., Heard, K.J., McCarthy, M.J., Eyler, L., Kelsoe, J.R., Santos, R., Marchetto, M.C., Gage, F.H. Altered Neuronal Support and Inflammatory Response in Bipolar Disorder Patient-Derived Astrocytes. (2021) Stem Cell Reports. DOI: 10.1016/j.stemcr.2021.02.004

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Santos, R., Linker, S.B., Stern, S., Mendes, A.P.D., Shokhirev, M.N., Erikson, G., Randolph-Moore, L., Racha, V., Kim, Y., Kelsoe, J.R., Bang, A.G., Alda, M., Marchetto, M.C., Gage, F.H. Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients. (2021) Molecular Psychiatry. DOI: 10.1038/s41380-020-00981-3

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Zholudeva, L.V., Abraira, V.E., Satkunendrarajah, K., McDevitt, T.C., Goulding, M.D., Magnuson, D.S.K., Lane, M.A. Spinal Interneurons as Gatekeepers to Neuroplasticity after Injury or Disease. (2021) 神经科学杂志. DOI: 10.1523/JNEUROSCI.1654-20.2020

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Trujillo, C.A., Adams, J.W., Negraes, P.D., Carromeu, C., Tejwani, L., Acab, A., Tsuda, B., Thomas, C.A., Sodhi, N., Fichter, K.M., Romero, S., Zanella, F., Sejnowski, T.J., Ulrich, H., Muotri, A.R. 药理学逆转人MECP2-KO神经元和皮层类器官中的突触和网络病理。. (2021) EMBO 分子医学. 13(1):e12523。DOI: 10.15252/emmm.202012523

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