韦特先进生物光子学中心

Pașca, S.P., Arlotta, P., Bateup, H.S., Camp, J.G., Cappello, S., Gage, F.H., Knoblich, J.A., Kriegstein, A.R., Lancaster, M.A., Ming, G.L., Novarino, G., Okano, H., Parmar, M., Park, I.H., Reiner, O., Song, H., Studer, L., Takahashi, J., Temple, S., Testa, G., Treutlein, B., Vaccarino, F.M., Vanderhaeghen, P., Young-Pearse, T. A framework for neural organoids, assembloids and transplantation studies. (2024) 自然. DOI: 10.1038/s41586-024-08487-6

Praturu, A., Sharpee, T.O. Adaptive data embedding for curved spaces. (2024) iScience. 27(12):111266. DOI: 10.1016/j.isci.2024.111266

Hirakis, S.P., Bartol, T.M., Autin, L., Amaro, R.E., Sejnowski, T.J. 分子水平的电生理心脏重塑：基于随机显式粒子模型的有关兰尼碱受体激活和钙诱导钙释放的见解。. (2024) 生物物理学报. DOI: 10.1016/j.bpj.2024.09.029

Patel, D., Sejnowski, T., Siegelmann, H. 基于时间分层架构的注意力与认知控制成本优化. (2024) 神经计算.:1-30 DOI: 10.1162/neco_a_01718

Son, G., Na, Y., Kim, Y., Son, J.H., Clemenson, G.D., Schafer, S.T., Yoo, J.Y., Parylak, S.L., Paquola, A., Do, H., Kim, D., Ahn, I., Ju, M., Kang, C.S., Ju, Y., Jung, E., McDonald, A.H., Park, Y., Kim, G., Paik, S.B., Hur, J., Kim, J., Han, Y.M., Lee, S.H., Gage, F.H., Kim, J.S., Han, J. miR-124 coordinates metabolic regulators acting at early stages of human neurogenesis. (2024) 传达生物学. 7(1):1393. DOI: 10.1038/s42003-024-07089-2

Barykina, N.V., Carey, E.M., Oliinyk, O.S., Nimmerjahn, A., Verkhusha, V.V. Destabilized near-infrared fluorescent nanobodies enable background-free targeting of GFP-based biosensors for imaging and manipulation. (2024) 自然-通讯. 15(1):7788. DOI: 10.1038/s41467-024-51857-x

Muller, L., Churchland, P.S., Sejnowski, T.J. Transformer 网络和皮质波：跨时提取上下文的编码器。. (2024) 神经科学趋势. DOI: 10.1016/j.tins.2024.08.006

Comstock, L., Carvalho, V.R., Lainscsek, C., Fallah, A., Sejnowski, T.J. 经颅磁刺激促进神经言语解码。. (2024) 脑科学. 14(9)。DOI：10.3390/brainsci14090895

Patiño, M., Rossa, M.A., Lagos, W.N., Patne, N.S., Callaway, E.M. Transcriptomic cell-type specificity of local cortical circuits. (2024) 神经元. DOI: 10.1016/j.neuron.2024.09.003

Fernandes, S., Revanna, J., Pratt, J., Hayes, N., Marchetto, M.C., Gage, F.H. Modeling Alzheimer's disease using human cell derived brain organoids and 3D models. (2024) 神经科学前沿. 18:1434945. DOI: 10.3389/fnins.2024.1434945

Minhas, P.S., Jones, J.R., Latif-Hernandez, A., Sugiura, Y., Durairaj, A.S., Wang, Q., Mhatre, S.D., Uenaka, T., Crapser, J., Conley, T., Ennerfelt, H., Jung, Y.J., Liu, L., Prasad, P., Jenkins, B.C., Ay, Y.A., Matrongolo, M., Goodman, R., Newmeyer, T., Heard, K., Kang, A., Wilson, E.N., Yang, T., Ullian, E.M., Serrano, G.E., Beach, T.G., Wernig, M., Rabinowitz, J.D., Suematsu, M., Longo, F.M., McReynolds, M.R., Gage, F.H., Andreasson, K.I. Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies. (2024) 科学. 385(6711):eabm6131. DOI: 10.1126/science.abm6131

Alvarez-Kuglen, M., Ninomiya, K., Qin, H., Rodriguez, D., Fiengo, L., Farhy, C., Hsu, W.M., Kirk, B., Havas, A., Feng, G.S., Roberts, A.J., Anderson, R.M., Serrano, M., Adams, P.D., Sharpee, T.O., Terskikh, A.V. ImAge quantitates aging and rejuvenation. (2024) Nat Aging. DOI: 10.1038/s43587-024-00685-1

Su, Y., Xu, J., Zhu, Z., Chin, J., Xu, L., Yu, H., Nudell, V., Dash, B., Moya, E.A., Ye, L., Nimmerjahn, A., Sun, X. Brainstem Dbh neurons control allergen-induced airway hyperreactivity. (2024) 自然. DOI: 10.1038/s41586-024-07608-5

Perez Garcia, G., Bicak, M., Buros, J., Haure-Mirande, J.V., Perez, G.M., Otero-Pagan, A., Gama Sosa, M.A., De Gasperi, R., Sano, M., Gage, F.H., Barlow, C., Dudley, J.T., Glicksberg, B.S., Wang, Y., Readhead, B., Ehrlich, M.E., Elder, G.A., Gandy, S. Beneficial effects of physical exercise and an orally active mGluR2/3 antagonist pro-drug on neurogenesis and behavior in an Alzheimer's amyloidosis model. (2024) Front Dement. 2:1198006. DOI: 10.3389/frdem.2023.1198006

Carvalho, V.R., Mendes, E.M.A.M., Fallah, A., Sejnowski, T.J., Comstock, L., Lainscsek, C. 延迟微分分析解码意念语音. (2024) 人类神经科学前沿. 18:1398065。DOI: 10.3389/fnhum.2024.1398065

Schmidt, T.T., Tyer, C., Rughani, P., Haggblom, C., Jones, J.R., Dai, X., Frazer, K.A., Gage, F.H., Juul, S., Hickey, S., Karlseder, J. 高分辨率长读长端粒测序揭示衰老与癌症的动态机制。. (2024) 自然-通讯. 15(1):5149。DOI: 10.1038/s41467-024-48917-7

Chen, Y., Zhang, H., Cameron, M., Sejnowski, T. 海马形成的预测序列学习. (2024) 神经元. 10.1016/j.neuron.2024.05.024

Phang, H.J., Heimler, S.R., Scandalis, L.M., Wing, D., Moran, R., Nichols, J.F., Moreno, D., Shadel, G.S., Gage, F.H., Molina, A.J.A. Protocol for the San Diego Nathan Shock Center Clinical Cohort: a new resource for studies of human aging. (2024) BMJ Open. 14(6):e082659. DOI: 10.1136/bmjopen-2023-082659

Herdy, J.R., Mertens, J., Gage, F.H. Neuronal senescence may drive brain aging. LINK TO FREE FULL-TEXT https://www.science.org/stoken/author-tokens/ST-1962/full [Pubmed] (2024) 科学. 384(6703):1404-1406. DOI: 10.1126/science.adi3450

Minhas, P.S., Jones, J.R., Latif-Hernandez, A., Sugiura, Y., Durairaj, A.S., Uenaka, T., Wang, Q., Mhatre, S.D., Liu, L., Conley, T., Ennerfelt, H., Jung, Y.J., Prasad, P., Jenkins, B.C., Goodman, R., Newmeyer, T., Heard, K., Kang, A., Wilson, E.N., Ullian, E.M., Serrano, G.E., Beach, T.G., Rabinowitz, J.D., Wernig, M., Suematsu, M., Longo, F.M., McReynolds, M.R., Gage, F.H., Andreasson, K.I. Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies. (2024) bioRxiv. DOI: 10.1101/2024.06.23.598940

Stern, S., Zhang, L., Wang, M., Wright, R., Rosh, I., Hussein, Y., Stern, T., Choudhary, A., Tripathi, U., Reed, P., Sadis, H., Nayak, R., Shemen, A., Agarwal, K., Cordeiro, D., Peles, D., Hang, Y., Mendes, A.P.D., Baul, T.D., Roth, J.G., Coorapati, S., Boks, M.P., McCombie, W.R., Hulshoff Pol, H., Brennand, K.J., Réthelyi, J.M., Kahn, R.S., Marchetto, M.C., Gage, F.H. Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission. (2024) Molecular Psychiatry. DOI: 10.1038/s41380-024-02561-1

Wu, Y., Temple, B.A., Sevilla, N., Zhang, J., Zhu, H., Zolotavin, P., Jin, Y., Duarte, D., Sanders, E., Azim, E., Nimmerjahn, A., Pfaff, S.L., Luan, L., Xie, C. Ultraflexible electrodes for recording neural activity in the mouse spinal cord during motor behavior. (2024) 细胞报告. 43(5):114199. DOI: 10.1016/j.celrep.2024.114199

Tripathi, U., Rosh, I., Ben Ezer, R., Nayak, R., Hussein, Y., Choudhary, A., Djamus, J., Manole, A., Houlden, H., Gage, F.H., Stern, S. Upregulated ECM genes and increased synaptic activity in Parkinson's human DA neurons with PINK1/ PRKN mutations. (2024) NPJ Parkinsons Dis. 10(1):103. DOI: 10.1038/s41531-024-00715-0

Mi, X., Chen, A.B., Duarte, D., Carey, E., Taylor, C.R., Braaker, P.N., Bright, M., Almeida, R.G., Lim, J.X., Rutten, V.M., Zheng, W., Wang, M., Reitman, M.E., Wang, Y., Poskanzer, K.E., Lyons, D.A., Nimmerjahn, A., Ahrens, M.B., Yu, G. Fast, Accurate, and Versatile Data Analysis Platform for the Quantification of Molecular Spatiotemporal Signals. (2024) bioRxiv. DOI: 10.1101/2024.05.02.592259

Zocher, S., McCloskey, A., Karasinsky, A., Schulte, R., Friedrich, U., Lesche, M., Rund, N., Gage, F.H., Hetzer, M.W., Toda, T. Lifelong persistence of nuclear RNAs in the mouse brain. (2024) 科学. 384(6691):53-59. DOI: 10.1126/science.adf3481

Samavat, M., Bartol, T.M., Harris, K.M., Sejnowski, T.J. 用信息论衡量突触信息存储容量. (2024) 神经计算. 36(5):781-802. DOI: 10.1162/neco_a_01659

Husar, A., Ordyan, M., Garcia, G.C., Yancey, J.G., Saglam, A.S., Faeder, J.R., Bartol, T.M., Kennedy, M.B., Sejnowski, T.J. MCell4 结合 BioNetGen：一个具备 Python 接口的基于规则的反应扩散系统蒙特卡洛模拟器。. (2024) PLOS计算生物学. 20(4):e1011800。DOI：10.1371/journal.pcbi.1011800

Adusei, M., Callaway, E.M., Usrey, W.M., Briggs, F. Parallel streams of direct corticogeniculate feedback from mid-level extrastriate cortex in the macaque monkey. (2024) eNeuro. DOI: 10.1523/ENEURO.0364-23.2024

Podvin, S., Jones, J., Kang, A., Goodman, R., Reed, P., Lietz, C.B., Then, J., Lee, K.C., Eyler, L.T., Jeste, D.V., Gage, F.H., Hook, V. Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. (2024) Molecular Psychiatry. DOI: 10.1038/s41380-024-02422-x

Toda, T., Bedrosian, T.A., Schafer, S.T., Cuoco, M.S., Linker, S.B., Ghassemzadeh, S., Mitchell, L., Whiteley, J.T., Novaresi, N., McDonald, A.H., Gallina, I.S., Yoon, H., Hester, M.E., Pena, M., Lim, C., Suljic, E., AlFatah Mansour, A., Boulard, M., Parylak, S.L., Gage, F.H. Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation. (2024) 细胞报告. 43(2):113774. DOI: 10.1016/j.celrep.2024.113774

Bartol, T.M., Ordyan, M., Sejnowski, T.J., Rangamani, P., Kennedy, M.B. 钙调蛋白依赖性激酶II (CaMKII) 在谷氨酸能棘突中磷酸化的空间模型提出了一种网络驱动的动力学机制，可实现突触强度的双稳态变化。. (2024) bioRxiv. DOI：10.1101/2024.02.02.578696

Rosh, I., Tripathi, U., Hussein, Y., Rike, W.A., Djamus, J., Shklyar, B., Manole, A., Houlden, H., Winkler, J., Gage, F.H., Stern, S. Synaptic dysfunction and extracellular matrix dysregulation in dopaminergic neurons from sporadic and E326K-GBA1 Parkinson's disease patients. (2024) NPJ Parkinsons Dis. 10(1):38. DOI: 10.1038/s41531-024-00653-x

Wang, H., Dey, O., Lagos, W.N., Behnam, N., Callaway, E.M., Stafford, B.K. Parallel pathways carrying direction-and orientation-selective retinal signals to layer 4 of the mouse visual cortex. (2024) 细胞报告. 43(3):113830. DOI: 10.1016/j.celrep.2024.113830

Miao, S., Fourgeaud, L., Burrola, P.G., Stern, S., Zhang, Y., Happonen, K.E., Novak, S.W., Gage, F.H., Lemke, G. Tyro3 promotes the maturation of glutamatergic synapses. (2024) 神经科学前沿. 18:1327423. DOI: 10.3389/fnins.2024.1327423

Wang, M., Zhang, L., Novak, S.W., Yu, J., Gallina, I.S., Xu, L.L., Lim, C.K., Fernandes, S., Shokhirev, M.N., Williams, A.E., Saxena, M.D., Coorapati, S., Parylak, S.L., Quintero, C., Molina, E., Andrade, L.R., Manor, U., Gage, F.H. Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain. (2024) Nature Biotechnology. DOI: 10.1038/s41587-024-02157-8

Sameni, S., Bartol, T.M., Corey-Bloom, J., Sejnowski, T.J. 计算机模拟预测了神经元萎缩对亨廷顿病钙动力学的影响。. (2024) PNAS Nexus. 3(1):pgad443。DOI：10.1093/pnasnexus/pgad443

Samavat, M., Bartol, T.M., Bromer, C., Hubbard, D.D., Hanka, D.C., Kuwajima, M., Mendenhall, J.M., Parker, P.H., Bowden, J.B., Abraham, W.C., Sejnowski, T.J., Harris, K.M. 长期增强可产生海马体成年大鼠突触信息存储容量的持续扩展。. (2024) bioRxiv. DOI: 10.1101/2024.01.12.574766

Zhang, L.A., Li, P., Callaway, E.M. High-Resolution Laminar Identification in Macaque Primary Visual Cortex Using Neuropixels Probes. (2024) bioRxiv. DOI: 10.1101/2024.01.23.576944