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Nobel laureate Elizabeth Blackburn named Salk Institute president

LA JOLLA—Nobel Prize-winning scientist Elizabeth Blackburn, a pioneering molecular biologist and highly respected leader in the scientific community, has been named president of the Salk Institute for Biological Studies.


Salk professor Ron Evans to co-lead ‘Dream Team’ of pancreatic cancer researchers from US, UK

LA JOLLA, CA—The Salk Institute will co-lead a new transatlantic ‘Dream Team’ of researchers that will launch a fresh attack on pancreatic cancer, one of the deadliest forms of cancer on both sides of the Atlantic. Stand Up To Cancer (SU2C), Cancer Research UK, and The Lustgarten Foundation selected the team and will provide $12 million in funding over three years.


Experimental drug targeting Alzheimer’s disease shows anti-aging effects

LA JOLLA–Salk Institute researchers have found that an experimental drug candidate aimed at combating Alzheimer’s disease has a host of unexpected anti-aging effects in animals.


Molecular “brake” stifles human lung cancer

LA JOLLA–Scientists at the Salk Institute have uncovered a molecule whose mutation leads to the aggressive growth of a common and deadly type of lung Krebs in humans.


‘Superhelden’-Darmbakterien schützen vor tödlichen Symptomen während einer Infektion

LA JOLLA – Angesichts wachsender Bedenken hinsichtlich tödlicher antibiotikaresistenter ‘Superbug’-Bakterienstämme bieten Wissenschaftler am Salk Institute eine mögliche Lösung für das Problem: ‘Superhelden’-Bakterien, die im Darm leben und sich in andere Körperteile bewegen, um lebensbedrohliche Nebenwirkungen von Infektionen zu lindern.


To scratch an itch is a hairy problem

LA JOLLA–An insect lands on your arm, moving the tiny hairs on your skin just enough to make you want to scratch. Salk Institute researchers have uncovered evidence of a dedicated neural pathway that transmits the itchy feeling triggered by such a light touch.


Bipolar patients’ brain cells predict response to lithium

LA JOLLA–The brain cells of patients with bipolar disorder, characterized by severe swings between depression and elation, are more sensitive to stimuli than other people’s brain cells, researchers have discovered.


Salk scientists discover protein factories hidden in human jumping genes

LA JOLLA–Scientists have discovered a previously unknown wellspring of genetic diversity in humans, chimps and most other primates. This diversity arises from a new component of itinerant sections of genetic code known as jumping genes.


Zelluläre Kontrollsysteme beim Schadenmanagement helfen Pflanzen, zäh zu werden

LA JOLLA–As food demands rise to unprecedented levels, farmers are in a race against time to grow plants that can withstand environmental challenges–infestation, climate change and more. Now, new research at the Salk Institute, published in Wissenschaft on October 23, 2015, reveals details into a fundamental mechanism of how plants manage their energy intake, which could potentially be harnessed to improve yield.


Targeting mutant proteins might be silver bullet for neurodegenerative diseases

LA JOLLA–Scientists have unraveled how mutant molecules damage the nervous system of people with Charcot-Marie-Tooth (CMT) disease, a group of disorders that hinder people’s ability to move and feel sensation in their hands and feet, according to a paper published October 21, 2015 in Natur.


Salk Fellows Dmitry Lyumkis and Patrick Hsu receive NIH Director’s Early Independence Award

LA JOLLA–Salk Fellows Dmitri Lyumkis und Patrick Hsu are among 16 scientists nationwide to receive the Director’s Early Independence Award from the Nationale Gesundheitsinstitute (NIH). The award supports junior scientists in their efforts to pursue innovative approaches to major contemporary challenges in biomedical research. Established in 2011, the Early Independence Award is part of the NIH’s High-Risk, High-Reward Research program, which encourages paradigm-shifting research projects that are inherently risky and untested.


Terrence Sejnowski receives Swartz Prize for Theoretical and Computational Neuroscience

LA JOLLA–The Society for Neuroscience (SfN), an organization of nearly 40,000 scientists and clinicians, will award the Swartz Prize for Theoretical and Computational Neuroscience to Terrence Sejnowski, Salk professor and head of the Labor für computergestützte Neurobiologie.


Janelle Ayres receives Young Faculty Award from DARPA

LA JOLLA–Salk Institute scientist Janelle Ayres has received an award of $500,000 over two years from the Defense Advanced Research Projects Agency (DARPA) to further her research on bolstering a person’s microbiome to help their body overcome an infection. The award comes with the possibility of an additional $500,000 for a third year.


Researchers learn how to grow old brain cells

LA JOLLA–For the first time, scientists can use skin samples from older patients to create brain cells without rolling back the youthfulness clock in the cells first. The new technique, which yields cells resembling those found in older people’s brains, will be a boon to scientists studying age-related diseases like Alzheimer’s and Parkinson’s.


Clodagh O’Shea awarded $3 million to unlock the “black box” of the nucleus

LA JOLLA–As part of a $120 million, 5-year initiative to understand the cell’s nucleus, the Nationale Gesundheitsinstitute (NIH) has awarded more than $30 million to San Diego researchers, including the Salk Institute and the Universität von Kalifornien, San Diego (UC San Diego). Salk Associate Professor Clodagh O’Shea has been awarded a grant of $3 million over 5 years, along with the possibility of tapping into an additional opportunity pool of $3 million each year for the period.


New Helmsley-Salk Fellow brings cutting-edge gene editing technologies to the Salk Institute

LA JOLLA—The Salk Institute is pleased to announce the appointment of bioengineer Patrick Hsu in the innovative Salk Fellows Programm. Hsu, who hails from Harvard University and MIT’s Broad Institute, aims to develop the next generation of medical therapeutics by harnessing the gene editing technology known as CRISPR. A gene editing technique originally derived from bacterial immune systems, CRISPR has recently made headlines for its use in modifying DNA with unprecedented ease and accuracy.


Mobile App zeichnet unsere unregelmäßigen Essgewohnheiten auf

LA JOLLA–Frühstück, Mittagessen und Abendessen? Für zu viele von uns laufen die drei Mahlzeiten des Tages eher so ab: Gebäck beim morgendlichen Meeting, Energydrink am Nachmittag und Pizza mitten in der Nacht. In Zellstoffwechsel Am 24. September präsentieren Wissenschaftler des Salk Institute tägliche Nahrungs- und Getränkeaufnahme-Daten, die von über 150 Teilnehmern einer mobilen Forschungs-App über drei Wochen gesammelt wurden. Sie zeigen, dass die Mehrheit der Menschen 15 Stunden oder länger isst, wobei weniger als ein Viertel der täglichen Kalorien vor Mittag konsumiert wird und mehr als ein Drittel nach 18 Uhr.


Tatyana Sharpee named to NSF team trying to crack olfactory code

LA JOLLA–Since the early 19th century, scientists have worked to unravel the mystery of olfaction, our sense of smell.


New grant will fund collaborative effort to build reproducible assays to model autism

LA JOLLAThe National Institutes of Health has awarded a $13 million grant over five years to develop and disseminate new stem cell-based technologies and assays for studying autism spectrum disorder (ASD) and other mental health diseases to a consortium of researchers at the Universität von Kalifornien, San Diego and the Salk Institute for Biological Studies, working in tandem with leaders in the biotechnology sector.


Can your sense of smell predict when you’ll die?

LA JOLLA–By measuring how worms move toward an appealing, food-like scent, researchers at the Salk Institute were able to predict whether the worms would be long-lived. The finding, published September 22, 2015 in the journal eLife, shows how nematodes (Caenorhabditis elegans) process information about the environment and how circuits in the brain change as an animal ages.