La Jolla, CA – In a developing organism, knowledge of right from left can often mean the difference between life and death. Certainly, the direction and ultimate destination in which an embryonic heart, lung, stomach or liver travels can be critical for the proper alignment of blood vessels and nerves so that normal life may proceed. Now, a team led by scientists at The Salk Institute for Biological Studies has discovered a molecular guide, in the form of a single gene, that helps youthful cells, tissues and organs decide in which direction to take their first fateful steps–whether to go left or right.
La Jolla, CA – Científicos del Instituto Salk anunciaron hoy dos hallazgos de investigación relacionados con el desarrollo de la aterosclerosis. Los hallazgos implican el descubrimiento de un ciclo de retroalimentación genética que contribuye a la formación de placas ateroescleróticas en las arterias del corazón y el papel de un gen de almacenamiento de grasa descrito previamente (PPARgamma) en este proceso.
La Jolla, CA – Neuroscientists at The Salk Institute showed that mice lacking a specific brain molecule exhibit reduced susceptibility to epileptic-type seizures. The findings suggest that this molecule, GluR6, may be a suitable target for development of new epilepsy drugs.
La Jolla, CA – Salk investigators have discovered that aging mice living in a stimulating environment display three times the number of new brain cells as mice who live in a non-stimulating environment. The age of the mice in the study was 18 months – the human equivalent of 65 years.
