Argueti-Ostrovsky, S., Lim, S.M., Arogundade, O.A., Diaz-Garcia, S., Yunisova, G., Meng, A., Hermann, A., Ong, K., Eremenko, E., Bravo-Hernandez, M., Driscoll, S.P., Lee, C.Z., Jiang, X., Stavsky, A., Barel, S., Shani, T., Kahn, J., Pfaff, S.L., Monsonego, A., Marsala, M., Ravits, J., Lagier-Tourenne, C., Israelson, A. Impaired nucleocytoplasmic transport in SOD1-mediated ALS. (2026) Mol Neurodegener. DOI: 10.1186/s13024-026-00930-8

Moore, J.D., Bachmann, L.C., McElvain, L.E., Pfaff, S.L., Dulac, C. A genetically-defined population of amygdalofugal neurons promotes suckling and early postnatal growth. (2025) bioRxiv. DOI: 10.1101/2025.10.18.683193

Molokanova, E., Zhou, T., Vasupal, P., Cherkas, V.P., Narute, P., Ferraz, M.S.A., Reiss, M., Almenar-Queralt, A., Chaldaiopoulou, G., de Souza, J.S., Hemati, H., Downey, F., Olajide, O.O., Thörn Perez, C., Puppo, F., Mesci, P., Pfaff, S.L., Kireev, D., Muotri, A.R., Savchenko, A. Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics. (2025) 自然-通讯. 16(1):7499. DOI: 10.1038/s41467-025-62637-6

Wu, Y., Temple, B.A., Sevilla, N., Zhang, J., Zhu, H., Zolotavin, P., Jin, Y., Duarte, D., Sanders, E., Azim, E., Nimmerjahn, A., Pfaff, S.L., Luan, L., Xie, C. Ultraflexible electrodes for recording neural activity in the mouse spinal cord during motor behavior. (2024) 细胞报告. 43(5):114199. DOI: 10.1016/j.celrep.2024.114199

Daboussi, L., Costaguta, G., Gullo, M., Jasinski, N., Pessino, V., O'Leary, B., Lettieri, K., Driscoll, S., Pfaff, S.L. Mitf is a Schwann cell sensor of axonal integrity that drives nerve repair. (2023) 细胞报告. 42(11):113282. DOI: 10.1016/j.celrep.2023.113282

Globig, A.M., Zhao, S., Roginsky, J., Maltez, V.I., Guiza, J., Avina-Ochoa, N., Heeg, M., Araujo Hoffmann, F., Chaudhary, O., Wang, J., Senturk, G., Chen, D., O'Connor, C., Pfaff, S., Germain, R.N., Schalper, K.A., Emu, B., Kaech, S.M. The β-adrenergic receptor links sympathetic nerves to T cell exhaustion. (2023) 自然. DOI: 10.1038/s41586-023-06568-6

Kobayashi, Y., Shigyo, M., Platoshyn, O., Marsala, S., Kato, T., Takamura, N., Yoshida, K., Kishino, A., Bravo-Hernandez, M., Juhas, S., Juhasova, J., Studenovska, H., Proks, V., Driscoll, S.P., Glenn, T.D., Pfaff, S.L., Ciacci, J.D., Marsala, M. Expandable Sendai-Virus-Reprogrammed Human iPSC-Neuronal Precursors: Post-Grafting Safety Characterization in Rats and Adult Pig. (2023) Cell Transplantation. 32:9636897221107009. DOI: 10.1177/09636897221107009

Hayashi, M., Gullo, M., Senturk, G., Di Costanzo, S., Nagasaki, S.C., Kageyama, R., Imayoshi, I., Goulding, M., Pfaff, S.L., Gatto, G. A spinal synergy of excitatory and inhibitory neurons coordinates ipsilateral body movements. (2023) bioRxiv. DOI: 10.1101/2023.03.21.533603

Ronzano, R., Skarlatou, S., Barriga, B.K., Bannatyne, B.A., Bhumbra, G.S., Foster, J.D., Moore, J.D., Lancelin, C., Pocratsky, A.M., Özyurt, M.G., Smith, C.C., Todd, A.J., Maxwell, D.J., Murray, A.J., Pfaff, S.L., Brownstone, R.M., Zampieri, N., Beato, M. Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled. (2022) Elife. 11. DOI: 10.7554/eLife.81976

Martins, L.F., Brambilla, I., Motta, A., de Pretis, S., Bhat, G.P., Badaloni, A., Malpighi, C., Amin, N.D., Imai, F., Almeida, R.D., Yoshida, Y., Pfaff, S.L., Bonanomi, D. Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity. (2022) 神经元. DOI: 10.1016/j.neuron.2022.09.021

Tadokoro, T., Bravo-Hernandez, M., Agashkov, K., Kobayashi, Y., Platoshyn, O., Navarro, M., Marsala, S., Miyanohara, A., Yoshizumi, T., Shigyo, M., Krotov, V., Juhas, S., Juhasova, J., Nguyen, D., Skalnikova, H.K., Motlik, J., Studenovska, H., Proks, V., Reddy, R., Driscoll, S.P., Glenn, T.D., Kemthong, T., Malaivijitnond, S., Tomori, Z., Vanicky, I., Kakinohana, M., Pfaff, S.L., Ciacci, J., Belan, P., Marsala, M. Precision spinal gene delivery-induced functional switch in nociceptive neurons reverses neuropathic pain. (2022) Molecular Therapy. DOI: 10.1016/j.ymthe.2022.04.023

Amin, N.D., Senturk, G., Hayashi, M., Driscoll, S.P., Pfaff, S.L. Detecting microRNA-mediated gene regulatory effects in murine neuronal subpopulations. (2022) STAR Protoc. 3(1):101130. DOI: 10.1016/j.xpro.2022.101130

Amin, N.D., Senturk, G., Costaguta, G., Driscoll, S., O'Leary, B., Bonanomi, D., Pfaff, S.L. A hidden threshold in motor neuron gene networks revealed by modulation of miR-218 dose. (2021) 神经元. DOI: 10.1016/j.neuron.2021.07.028

Osseward, P.J., Amin, N.D., Moore, J.D., Temple, B.A., Barriga, B.K., Bachmann, L.C., Beltran, F., Gullo, M., Clark, R.C., Driscoll, S.P., Pfaff, S.L., Hayashi, M. Conserved genetic signatures parcellate cardinal spinal neuron classes into local and projection subsets. (2021) 科学. 372(6540):385-393. DOI: 10.1126/science.abe0690

Marsala, M., Kamizato, K., Tadokoro, T., Navarro, M., Juhas, S., Juhasova, J., Marsala, S., Studenovska, H., Proks, V., Hazel, T., Johe, K., Kakinohana, M., Driscoll, S., Thomas, G., Pfaff, S., Ciacci, J. Spinal parenchymal occupation by neural stem cells after subpial delivery in adult immunodeficient rats. (2019) Stem Cells Translational Medicine. DOI: 10.1002/sctm.19-0156

Reichenstein, I., Eitan, C., Diaz-Garcia, S., Haim, G., Magen, I., Siany, A., Hoye, M.L., Rivkin, N., Olender, T., Toth, B., Ravid, R., Mandelbaum, A.D., Yanowski, E., Liang, J., Rymer, J.K., Levy, R., Beck, G., Ainbinder, E., Farhan, S.M.K., Lennox, K.A., Bode, N.M., Behlke, M.A., Möller, T., Saxena, S., Moreno, C.A.M., Costaguta, G., van Eijk, K.R., Phatnani, H., Al-Chalabi, A., Başak, A.N., van den Berg, L.H., Hardiman, O., Landers, J.E., Mora, J.S., Morrison, K.E., Shaw, P.J., Veldink, J.H., Pfaff, S.L., Yizhar, O., Gross, C., Brown, R.H., Ravits, J.M., Harms, M.B., Miller, T.M., Hornstein, E. Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology. (2019) Science Translational Medicine. 11(523). DOI: 10.1126/scitranslmed.aav5264

Bravo-Hernandez, M., Tadokoro, T., Navarro, M.R., Platoshyn, O., Kobayashi, Y., Marsala, S., Miyanohara, A., Juhas, S., Juhasova, J., Skalnikova, H., Tomori, Z., Vanicky, I., Studenovska, H., Proks, V., Chen, P., Govea-Perez, N., Ditsworth, D., Ciacci, J.D., Gao, S., Zhu, W., Ahrens, E.T., Driscoll, S.P., Glenn, T.D., McAlonis-Downes, M., Da Cruz, S., Pfaff, S.L., Kaspar, B.K., Cleveland, D.W., Marsala, M. Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS. (2019) Nature Medicine. DOI: 10.1038/s41591-019-0674-1

Osseward, P.J., Pfaff, S.L. Cell type and circuit modules in the spinal cord. (2019) 当前神经生物学评论. 56:175-184. DOI: 10.1016/j.conb.2019.03.003

Bohaciakova, D., Hruska-Plochan, M., Tsunemoto, R., Gifford, W.D., Driscoll, S.P., Glenn, T.D., Wu, S., Marsala, S., Navarro, M., Tadokoro, T., Juhas, S., Juhasova, J., Platoshyn, O., Piper, D., Sheckler, V., Ditsworth, D., Pfaff, S.L., Marsala, M. A scalable solution for isolating human multipotent clinical-grade neural stem cells from ES precursors. (2019) Stem Cell Research & Therapy. 10(1):83. DOI: 10.1186/s13287-019-1163-7

Bonanomi, D., Valenza, F., Chivatakarn, O., Sternfeld, M.J., Driscoll, S.P., Aslanian, A., Lettieri, K., Gullo, M., Badaloni, A., Lewcock, J.W., Hunter, T., Pfaff, S.L. p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts. (2019) 神经元. DOI: 10.1016/j.neuron.2019.02.034

Strnadel, J., Carromeu, C., Bardy, C., Navarro, M., Platoshyn, O., Glud, A.N., Marsala, S., Kafka, J., Miyanohara, A., Kato, T., Tadokoro, T., Hefferan, M.P., Kamizato, K., Yoshizumi, T., Juhas, S., Juhasova, J., Ho, C.S., Kheradmand, T., Chen, P., Bohaciakova, D., Hruska-Plochan, M., Todd, A.J., Driscoll, S.P., Glenn, T.D., Pfaff, S.L., Klima, J., Ciacci, J., Curtis, E., Gage, F.H., Bui, J., Yamada, K., Muotri, A.R., Marsala, M. Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs. (2018) Science Translational Medicine. 10(440). DOI: 10.1126/scitranslmed.aam6651

Mo, Z., Zhao, X., Liu, H., Hu, Q., Chen, X.Q., Pham, J., Wei, N., Liu, Z., Zhou, J., Burgess, R.W., Pfaff, S.L., Caskey, C.T., Wu, C., Bai, G., Yang, X.L. Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy. (2018) 自然-通讯. 9(1):1007. DOI: 10.1038/s41467-018-03461-z

Hayashi, M., Hinckley, C.A., Driscoll, S.P., Moore, N.J., Levine, A.J., Hilde, K.L., Sharma, K., Pfaff, S.L. Graded Arrays of Spinal and Supraspinal V2a Interneuron Subtypes Underlie Forelimb and Hindlimb Motor Control. (2018) 神经元. DOI: 10.1016/j.neuron.2018.01.023

Sternfeld, M.J., Hinckley, C.A., Moore, N.J., Pankratz, M.T., Hilde, K.L., Driscoll, S.P., Hayashi, M., Amin, N.D., Bonanomi, D., Gifford, W.D., Sharma, K., Goulding, M., Pfaff, S.L. Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells. (2017) Elife. 6. DOI: 10.7554/eLife.21540

Hilde, K.L., Levine, A.J., Hinckley, C.A., Hayashi, M., Montgomery, J.M., Gullo, M., Driscoll, S.P., Grosschedl, R., Kohwi, Y., Kohwi-Shigematsu, T., Pfaff, S.L. Satb2 Is Required for the Development of a Spinal Exteroceptive Microcircuit that Modulates Limb Position. (2016) 神经元. 91(4):763-776. DOI: 10.1016/j.neuron.2016.07.014

Wasson, J.A., Simon, A.K., Myrick, D.A., Wolf, G., Driscoll, S., Pfaff, S.L., Macfarlan, T.S., Katz, D.J. Maternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally. (2016) Elife. 5. DOI: 10.7554/eLife.08848

Geeven, G., Zhu, Y., Kim, B.J., Bartholdy, B.A., Yang, S.M., Macfarlan, T.S., Gifford, W.D., Pfaff, S.L., Verstegen, M.J., Pinto, H., Vermunt, M.W., Creyghton, M.P., Wijchers, P.J., Stamatoyannopoulos, J.A., Skoultchi, A.I., de Laat, W. Local compartment changes and regulatory landscape alterations in histone H1-depleted cells. (2015) 基因组生物学. 16:289. DOI: 10.1186/s13059-015-0857-0

Amin, N.D., Bai, G., Klug, J.R., Bonanomi, D., Pankratz, M.T., Gifford, W.D., Hinckley, C.A., Sternfeld, M.J., Driscoll, S.P., Dominguez, B., Lee, K.F., Jin, X., Pfaff, S.L. Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure. (2015) 科学. 350(6267):1525-9. DOI: 10.1126/science.aad2509

Pan, F.C., Brissova, M., Powers, A.C., Pfaff, S., Wright, C.V. Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells. (2015) Development. 142(21):3637-48. DOI: 10.1242/dev.126011

He, W., Bai, G., Zhou, H., Wei, N., White, N.M., Lauer, J., Liu, H., Shi, Y., Dumitru, C.D., Lettieri, K., Shubayev, V., Jordanova, A., Guergueltcheva, V., Griffin, P.R., Burgess, R.W., Pfaff, S.L., Yang, X.L. CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. (2015) 自然. 526(7575):710-4. DOI: 10.1038/nature15510

Pawar, K., Cummings, B.J., Thomas, A., Shea, L.D., Levine, A., Pfaff, S., Anderson, A.J. Biomaterial bridges enable regeneration and re-entry of corticospinal tract axons into the caudal spinal cord after SCI: Association with recovery of forelimb function. (2015) Biomaterials. 65:1-12. DOI: 10.1016/j.biomaterials.2015.05.032

Hinckley, C.A., Alaynick, W.A., Gallarda, B.W., Hayashi, M., Hilde, K.L., Driscoll, S.P., Dekker, J.D., Tucker, H.O., Sharpee, T.O., Pfaff, S.L. Spinal Locomotor Circuits Develop Using Hierarchical Rules Based on Motorneuron Position and Identity. (2015) 神经元. 87(5):1008-21. DOI: 10.1016/j.neuron.2015.08.005

Wang, J., Telese, F., Tan, Y., Li, W., Jin, C., He, X., Basnet, H., Ma, Q., Merkurjev, D., Zhu, X., Liu, Z., Zhang, J., Ohgi, K., Taylor, H., White, R.R., Tazearslan, C., Suh, Y., Macfarlan, T.S., Pfaff, S.L., Rosenfeld, M.G. LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control. (2015) 自然神经科学. 18(9):1256-64. DOI: 10.1038/nn.4069

Lee, H., Kim, M., Kim, N., Macfarlan, T., Pfaff, S.L., Mastick, G.S., Song, M.R. Slit and Semaphorin signaling governed by Islet transcription factors positions motor neuron somata within the neural tube. (2015) Experimental Neurology. 269:17-27. DOI: 10.1016/j.expneurol.2015.03.024

Pei, L., Mu, Y., Leblanc, M., Alaynick, W., Barish, G.D., Pankratz, M., Tseng, T.W., Kaufman, S., Liddle, C., Yu, R.T., Downes, M., Pfaff, S.L., Auwerx, J., Gage, F.H., Evans, R.M. Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism. (2015) Cell Metabolism. 21(4):628-36. DOI: 10.1016/j.cmet.2015.03.004

Wang, L., Mongera, A., Bonanomi, D., Cyganek, L., Pfaff, S.L., Nüsslein-Volhard, C., Marquardt, T. A conserved axon type hierarchy governing peripheral nerve assembly. (2014) Development. 141(9):1875-83. DOI: 10.1242/dev.106211

Levine, A.J., Hinckley, C.A., Hilde, K.L., Driscoll, S.P., Poon, T.H., Montgomery, J.M., Pfaff, S.L. Identification of a cellular node for motor control pathways. (2014) 自然神经科学. 17(4):586-93. DOI: 10.1038/nn.3675

Pfaff, S., Shaham, S. Development of neurons and glia. (2013) 当前神经生物学评论. 23(6):901-2.

Hsu, C.C., White, N.M., Hayashi, M., Lin, E.C., Poon, T., Banerjee, I., Chen, J., Pfaff, S.L., Macagno, E.R., Dorrestein, P.C. Microscopy ambient ionization top-down mass spectrometry reveals developmental patterning. (2013) 美国国家科学院院刊. 110(37):14855-60. DOI: 10.1073/pnas.1310618110

Gifford, W.D., Pfaff, S.L., Macfarlan, T.S. Transposable elements as genetic regulatory substrates in early development. (2013) Trends in Cell Biology. 23(5):218-26. DOI: 10.1016/j.tcb.2013.01.001

Hinckley, C.A., Pfaff, S.L. Imaging spinal neuron ensembles active during locomotion with genetically encoded calcium indicators. (2013) Ann. N. Y. Acad. Sci. 1279:71-9. DOI: 10.1111/nyas.12092

Rowe, H.M., Kapopoulou, A., Corsinotti, A., Fasching, L., Macfarlan, T.S., Tarabay, Y., Viville, S., Jakobsson, J., Pfaff, S.L., Trono, D. TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells. (2013) Genome Research. 23(3):452-61. DOI: 10.1101/gr.147678.112

Levine, A.J., Lewallen, K.A., Pfaff, S.L. Spatial organization of cortical and spinal neurons controlling motor behavior. (2012) 当前神经生物学评论. 22(5):812-21. DOI: 10.1016/j.conb.2012.07.002

Macfarlan, T.S., Gifford, W.D., Driscoll, S., Lettieri, K., Rowe, H.M., Bonanomi, D., Firth, A., Singer, O., Trono, D., Pfaff, S.L. Embryonic stem cell potency fluctuates with endogenous retrovirus activity. (2012) 自然. 487(7405):57-63. DOI: 10.1038/nature11244

Bonanomi, D., Chivatakarn, O., Bai, G., Abdesselem, H., Lettieri, K., Marquardt, T., Pierchala, B.A., Pfaff, S.L. Ret is a multifunctional coreceptor that integrates diffusible- and contact-axon guidance signals. (2012) 牢房. 148(3):568-82. DOI: 10.1016/j.cell.2012.01.024

Bai, G., Pfaff, S.L. Protease regulation: the Yin and Yang of neural development and disease. (2011) 神经元. 72(1):9-21. DOI: 10.1016/j.neuron.2011.09.012

Kawakami, Y., Marti, M., Kawakami, H., Itou, J., Quach, T., Johnson, A., Sahara, S., O'Leary, D.D., Nakagawa, Y., Lewandoski, M., Pfaff, S., Evans, S.M., Izpisua Belmonte, J.C. Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice. (2011) Development. 138(20):4465-73. DOI: 10.1242/dev.065359

Hester, M.E., Murtha, M.J., Song, S., Rao, M., Miranda, C.J., Meyer, K., Tian, J., Boulting, G., Schaffer, D.V., Zhu, M.X., Pfaff, S.L., Gage, F.H., Kaspar, B.K. Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes. (2011) Mol. Ther. 19(10):1905-12. DOI: 10.1038/mt.2011.135

Alaynick, W.A., Jessell, T.M., Pfaff, S.L. SnapShot: spinal cord development. (2011) 牢房. 146(1):178-178.e1. DOI: 10.1016/j.cell.2011.06.038

Liang, X., Song, M.R., Xu, Z., Lanuza, G.M., Liu, Y., Zhuang, T., Chen, Y., Pfaff, S.L., Evans, S.M., Sun, Y. Isl1 is required for multiple aspects of motor neuron development. (2011) Molecular and Cellular Neurosciences. 47(3):215-22. DOI: 10.1016/j.mcn.2011.04.007

Bruno, I.G., Karam, R., Huang, L., Bhardwaj, A., Lou, C.H., Shum, E.Y., Song, H.W., Corbett, M.A., Gifford, W.D., Gecz, J., Pfaff, S.L., Wilkinson, M.F. Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay. (2011) 分子细胞. 42(4):500-10. DOI: 10.1016/j.molcel.2011.04.018

Macfarlan, T.S., Gifford, W.D., Agarwal, S., Driscoll, S., Lettieri, K., Wang, J., Andrews, S.E., Franco, L., Rosenfeld, M.G., Ren, B., Pfaff, S.L. Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A. (2011) 基因与发展. 25(6):594-607. DOI: 10.1101/gad.2008511

Garudadri, S., Gallarda, B., Pfaff, S., Alaynick, W. Spinal cord electrophysiology II: extracellular suction electrode fabrication. (2011) J Vis Exp.(48) DOI: 10.3791/2580

Bai, G., Chivatakarn, O., Bonanomi, D., Lettieri, K., Franco, L., Xia, C., Stein, E., Ma, L., Lewcock, J.W., Pfaff, S.L. Presenilin-dependent receptor processing is required for axon guidance. (2011) 牢房. 144(1):106-18. DOI: 10.1016/j.cell.2010.11.053

Qu, Y., Glasco, D.M., Zhou, L., Sawant, A., Ravni, A., Fritzsch, B., Damrau, C., Murdoch, J.N., Evans, S., Pfaff, S.L., Formstone, C., Goffinet, A.M., Chandrasekhar, A., Tissir, F. Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. (2010) 神经科学杂志. 30(28):9392-401. DOI: 10.1523/JNEUROSCI.0124-10.2010

Gallarda, B.W., Sharpee, T.O., Pfaff, S.L., Alaynick, W.A. Defining rhythmic locomotor burst patterns using a continuous wavelet transform. (2010) Ann. N. Y. Acad. Sci. 1198:133-9. DOI: 10.1111/j.1749-6632.2010.05437.x

Zhang, M., Liu, J., Kim, Y., Dixon, J.E., Pfaff, S.L., Gill, G.N., Noel, J.P., Zhang, Y. Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1. (2010) Protein Science. 19(5):974-86. DOI: 10.1002/pro.375

Bonanomi, D., Pfaff, S.L. Motor axon pathfinding. (2010) 冷泉港生物学述评. 2(3):a001735. DOI: 10.1101/cshperspect.a001735

Meyer, A., Gallarda, B.W., Pfaff, S., Alaynick, W. Spinal cord electrophysiology. (2010) J Vis Exp.(35) DOI: 10.3791/1660

Song, M.R., Sun, Y., Bryson, A., Gill, G.N., Evans, S.M., Pfaff, S.L. Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity. (2009) Development. 136(17):2923-32. DOI: 10.1242/dev.037986

Cao, X., Pfaff, S.L., Gage, F.H. YAP regulates neural progenitor cell number via the TEA domain transcription factor. (2008) 基因与发展. 22(23):3320-34. DOI: 10.1101/gad.1726608

Pfaff, S.L. Developmental neuroscience: Hox and Fox. (2008) 自然. 455(7211):295-7. DOI: 10.1038/455295a

Lee, S., Lee, B., Joshi, K., Pfaff, S.L., Lee, J.W., Lee, S.K. A regulatory network to segregate the identity of neuronal subtypes. (2008) 发育细胞. 14(6):877-89. DOI: 10.1016/j.devcel.2008.03.021

Gallarda, B.W., Bonanomi, D., Müller, D., Brown, A., Alaynick, W.A., Andrews, S.E., Lemke, G., Pfaff, S.L., Marquardt, T. Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling. (2008) 科学. 320(5873):233-6. DOI: 10.1126/science.1153758

Ma, Y.C., Song, M.R., Park, J.P., Henry Ho, H.Y., Hu, L., Kurtev, M.V., Zieg, J., Ma, Q., Pfaff, S.L., Greenberg, M.E. Regulation of motor neuron specification by phosphorylation of neurogenin 2. (2008) 神经元. 58(1):65-77. DOI: 10.1016/j.neuron.2008.01.037

Ghosh, S., Marquardt, T., Thaler, J.P., Carter, N., Andrews, S.E., Pfaff, S.L., Hunter, T. Instructive role of aPKCzeta subcellular localization in the assembly of adherens junctions in neural progenitors. (2008) 美国国家科学院院刊. 105(1):335-40. DOI: 10.1073/pnas.0705713105

Lewcock, J.W., Genoud, N., Lettieri, K., Pfaff, S.L. The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics. (2007) 神经元. 56(4):604-20. DOI: 10.1016/j.neuron.2007.09.009

Fox, M.A., Sanes, J.R., Borza, D.B., Eswarakumar, V.P., Fässler, R., Hudson, B.G., John, S.W., Ninomiya, Y., Pedchenko, V., Pfaff, S.L., Rheault, M.N., Sado, Y., Segal, Y., Werle, M.J., Umemori, H. Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals. (2007) 牢房. 129(1):179-93. DOI: 10.1016/j.cell.2007.02.035

Cao, X., Pfaff, S.L., Gage, F.H. A functional study of miR-124 in the developing neural tube. (2007) 基因与发展. 21(5):531-6. DOI: 10.1101/gad.1519207

Peng, C.Y., Yajima, H., Burns, C.E., Zon, L.I., Sisodia, S.S., Pfaff, S.L., Sharma, K. Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord. (2007) 神经元. 53(6):813-27. DOI: 10.1016/j.neuron.2007.02.019

Odani, N., Pfaff, S.L., Nakamura, H., Funahashi, J. Cloning and developmental expression of a chick G-protein-coupled receptor SCGPR1. (2007) Gene Expression Patterns. 7(4):375-80. DOI: 10.1016/j.modgep.2006.12.003

Zhang, Y., Kim, Y., Genoud, N., Gao, J., Kelly, J.W., Pfaff, S.L., Gill, G.N., Dixon, J.E., Noel, J.P. Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1. (2006) 分子细胞. 24(5):759-70. DOI: 10.1016/j.molcel.2006.10.027

Song, M.R., Shirasaki, R., Cai, C.L., Ruiz, E.C., Evans, S.M., Lee, S.K., Pfaff, S.L. T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration. (2006) Development. 133(24):4945-55. DOI: 10.1242/dev.02694

Kashani, A.H., Qiu, Z., Jurata, L., Lee, S.K., Pfaff, S., Goebbels, S., Nave, K.A., Ghosh, A. Calcium activation of the LMO4 transcription complex and its role in the patterning of thalamocortical connections. (2006) 神经科学杂志. 26(32):8398-408. DOI: 10.1523/JNEUROSCI.0618-06.2006

Zhao, Y., Morales, D.C., Hermesz, E., Lee, W.K., Pfaff, S.L., Westphal, H. Reduced expression of the LIM-homeobox gene Lhx3 impairs growth and differentiation of Rathke's pouch and increases cell apoptosis during mouse pituitary development. (2006) Mechanisms of Development. 123(8):605-13. DOI: 10.1016/j.mod.2006.06.005

Shirasaki, R., Lewcock, J.W., Lettieri, K., Pfaff, S.L. FGF as a target-derived chemoattractant for developing motor axons genetically programmed by the LIM code. (2006) 神经元. 50(6):841-53. DOI: 10.1016/j.neuron.2006.04.030

Song, M.R., Pfaff, S.L. Hox genes: the instructors working at motor pools. (2005) 牢房. 123(3):363-5. DOI: 10.1016/j.cell.2005.10.014

Myers, C.P., Lewcock, J.W., Hanson, M.G., Gosgnach, S., Aimone, J.B., Gage, F.H., Lee, K.F., Landmesser, L.T., Pfaff, S.L. Cholinergic input is required during embryonic development to mediate proper assembly of spinal locomotor circuits. (2005) 神经元. 46(1):37-49. DOI: 10.1016/j.neuron.2005.02.022

Marquardt, T., Shirasaki, R., Ghosh, S., Andrews, S.E., Carter, N., Hunter, T., Pfaff, S.L. Coexpressed EphA receptors and ephrin-A ligands mediate opposing actions on growth cone navigation from distinct membrane domains. (2005) 牢房. 121(1):127-39. DOI: 10.1016/j.cell.2005.01.020

Goulding, M., Pfaff, S.L. Development of circuits that generate simple rhythmic behaviors in vertebrates. (2005) 当前神经生物学评论. 15(1):14-20. DOI: 10.1016/j.conb.2005.01.017

Lee, S.K., Jurata, L.W., Nowak, R., Lettieri, K., Kenny, D.A., Pfaff, S.L., Gill, G.N. The LIM domain-only protein LMO4 is required for neural tube closure. (2005) Molecular and Cellular Neurosciences. 28(2):205-14. DOI: 10.1016/j.mcn.2004.04.010

Lee, S.K., Lee, B., Ruiz, E.C., Pfaff, S.L. Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells. (2005) 基因与发展. 19(2):282-94. DOI: 10.1101/gad.1257105

Yeo, M., Lee, S.K., Lee, B., Ruiz, E.C., Pfaff, S.L., Gill, G.N. Small CTD phosphatases function in silencing neuronal gene expression. (2005) 科学. 307(5709):596-600. DOI: 10.1126/science.1100801

Cepeda-Nieto, A.C., Pfaff, S.L., Varela-Echavarría, A. Homeodomain transcription factors in the development of subsets of hindbrain reticulospinal neurons. (2005) Molecular and Cellular Neurosciences. 28(1):30-41. DOI: 10.1016/j.mcn.2004.06.016

Pak, W., Hindges, R., Lim, Y.S., Pfaff, S.L., O'Leary, D.D. Magnitude of binocular vision controlled by islet-2 repression of a genetic program that specifies laterality of retinal axon pathfinding. (2004) 牢房. 119(4):567-78. DOI: 10.1016/j.cell.2004.10.026

Schwander, M., Shirasaki, R., Pfaff, S.L., Müller, U. Beta1 integrins in muscle, but not in motor neurons, are required for skeletal muscle innervation. (2004) 神经科学杂志. 24(37):8181-91. DOI: 10.1523/JNEUROSCI.1345-04.2004

Weiner, J.A., Koo, S.J., Nicolas, S., Fraboulet, S., Pfaff, S.L., Pourquié, O., Sanes, J.R. Axon fasciculation defects and retinal dysplasias in mice lacking the immunoglobulin superfamily adhesion molecule BEN/ALCAM/SC1. (2004) Molecular and Cellular Neurosciences. 27(1):59-69. DOI: 10.1016/j.mcn.2004.06.005

Lee, S.K., Jurata, L.W., Funahashi, J., Ruiz, E.C., Pfaff, S.L. Analysis of embryonic motoneuron gene regulation: derepression of general activators function in concert with enhancer factors. (2004) Development. 131(14):3295-306. DOI: 10.1242/dev.01179

Thaler, J.P., Koo, S.J., Kania, A., Lettieri, K., Andrews, S., Cox, C., Jessell, T.M., Pfaff, S.L. A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity. (2004) 神经元. 41(3):337-50.

Cai, C.L., Liang, X., Shi, Y., Chu, P.H., Pfaff, S.L., Chen, J., Evans, S. Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. (2003) 发育细胞. 5(6):877-89.

Lee, S.K., Pfaff, S.L. Synchronization of neurogenesis and motor neuron specification by direct coupling of bHLH and homeodomain transcription factors. (2003) 神经元. 38(5):731-45.

Koo, S.J., Pfaff, S.L. Fine-tuning motor neuron properties: signaling from the periphery. (2002) 神经元. 35(5):823-6.

Hu, W.Y., Myers, C.P., Kilzer, J.M., Pfaff, S.L., Bushman, F.D. Inhibition of retroviral pathogenesis by RNA interference. (2002) 当前生物学。. 12(15):1301-11.

Thaler, J.P., Lee, S.K., Jurata, L.W., Gill, G.N., Pfaff, S.L. LIM factor Lhx3 contributes to the specification of motor neuron and interneuron identity through cell-type-specific protein-protein interactions. (2002) 牢房. 110(2):237-49.

Shirasaki, R., Pfaff, S.L. Transcriptional codes and the control of neuronal identity. (2002) 神经科学年度评论》。. 25:251-81. DOI: 10.1146/annurev.neuro.25.112701.142916

Lee, S.K., Pfaff, S.L. Transcriptional networks regulating neuronal identity in the developing spinal cord. (2001) 自然神经科学. 4 Suppl:1183-91. DOI: 10.1038/nn750

Marquardt, T., Pfaff, S.L. Cracking the transcriptional code for cell specification in the neural tube. (2001) 牢房. 106(6):651-4.

Lin, W., Burgess, R.W., Dominguez, B., Pfaff, S.L., Sanes, J.R., Lee, K.F. Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse. (2001) 自然. 410(6832):1057-64. DOI: 10.1038/35074025

Sharma, K., Leonard, A.E., Lettieri, K., Pfaff, S.L. Genetic and epigenetic mechanisms contribute to motor neuron pathfinding. (2000) 自然. 406(6795):515-9. DOI: 10.1038/35020078

Brown, A., Yates, P.A., Burrola, P., Ortuño, D., Vaidya, A., Jessell, T.M., Pfaff, S.L., O'Leary, D.D., Lemke, G. Topographic mapping from the retina to the midbrain is controlled by relative but not absolute levels of EphA receptor signaling. (2000) 牢房. 102(1):77-88.

Jurata, L.W., Thomas, J.B., Pfaff, S.L. Transcriptional mechanisms in the development of motor control. (2000) 当前神经生物学评论. 10(1):72-9.

Harrison, K.A., Thaler, J., Pfaff, S.L., Gu, H., Kehrl, J.H. Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice. (1999) 自然遗传学. 23(1):71-5. DOI: 10.1038/12674

Thaler, J., Harrison, K., Sharma, K., Lettieri, K., Kehrl, J., Pfaff, S.L. Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9. (1999) 神经元. 23(4):675-87.

Sharma, K., Sheng, H.Z., Lettieri, K., Li, H., Karavanov, A., Potter, S., Westphal, H., Pfaff, S.L. LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. (1998) 牢房. 95(6):817-28.

Takuma, N., Sheng, H.Z., Furuta, Y., Ward, J.M., Sharma, K., Hogan, B.L., Pfaff, S.L., Westphal, H., Kimura, S., Mahon, K.A. Formation of Rathke's pouch requires dual induction from the diencephalon. (1998) Development. 125(23):4835-40.

Pfaff, S.L., Taylor, W.L. Xenopus TFIIIA gene transcription is dependent on cis-element positioning and chromatin structure. (1998) 分子与细胞生物学. 18(7):3811-8.

Pfaff, S., Kintner, C. Neuronal diversification: development of motor neuron subtypes. (1998) 当前神经生物学评论. 8(1):27-36.

Jurata, L.W., Pfaff, S.L., Gill, G.N. The nuclear LIM domain interactor NLI mediates homo- and heterodimerization of LIM domain transcription factors. (1998) 生物化学杂志. 273(6):3152-7.

Ahlgren, U., Pfaff, S.L., Jessell, T.M., Edlund, T., Edlund, H. Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells. (1997) 自然. 385(6613):257-60. DOI: 10.1038/385257a0

Varela-Echavarría, A., Pfaff, S.L., Guthrie, S. Differential expression of LIM homeobox genes among motor neuron subpopulations in the developing chick brain stem. (1996) Molecular and Cellular Neurosciences. 8(4):242-57. DOI: 10.1006/mcne.1996.0061

Pfaff, S.L., Mendelsohn, M., Stewart, C.L., Edlund, T., Jessell, T.M. Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. (1996) 牢房. 84(2):309-20.

Tsuchida, T., Ensini, M., Morton, S.B., Baldassare, M., Edlund, T., Jessell, T.M., Pfaff, S.L. Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. (1994) 牢房. 79(6):957-70.

Yamada, T., Pfaff, S.L., Edlund, T., Jessell, T.M. Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate. (1993) 牢房. 73(4):673-86.

Pfaff, S.L., Taylor, W.L. Characterization of a Xenopus oocyte factor that binds to a developmentally regulated cis-element in the TFIIIA gene. (1992) Developmental Biology. 151(1):306-16.

Pfaff, S.L., Hall, R.K., Hart, G.C., Taylor, W.L. Regulation of the Xenopus laevis transcription factor IIIA gene during oogenesis and early embryogenesis: negative elements repress the O-TFIIIA promoter in embryonic cells. (1991) Developmental Biology. 145(2):241-54.

Pfaff, S.L., Tamkun, M.M., Taylor, W.L. pOEV: a Xenopus oocyte protein expression vector. (1990) Analytical Biochemistry. 188(1):192-9.

Pfaff, S.L., Duesberg, P.H. Two autonomous myc oncogenes in avian carcinoma virus OK10. (1988) 病毒学杂志. 62(10):3703-9.

Pfaff, S.L., Zhou, R.P., Young, J.C., Hayflick, J., Duesberg, P.H. Defining the borders of the chicken proto-fps gene, a precursor of Fujinami sarcoma virus. (1985) Virology. 146(2):307-14.