马丁-古尔丁,博士

教授

分子神经生物学实验室

Frederick W. and Joanna J. Mitchell Chair

索尔克生物研究所 出版物

所有出版物


Virlogeux, A., Bollu, T., Ren, X., Palma, A.M., Goulding, M.D. The dorsal column nuclei encode and transmit the network signatures of mechanical allodynia. (2025) 细胞报告. 44(9):116248. DOI: 10.1016/j.celrep.2025.116248

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Kang, S.J., Liu, S., Kim, J.H., Kim, D.I., Oh, T.G., Peng, J., Ye, M., Lee, K.F., Evans, R.M., Goulding, M., Han, S. Thalamic CGRP neurons define a spinothalamic pathway for affective pain. (2025) 美国国家科学院院刊. 122(28):e2505889122. DOI: 10.1073/pnas.2505889122

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Yao, M., Nagamori, A., Campos Maçãs, S., Azim, E., Sharpee, T., Goulding, M., Golomb, D., Gatto, G. The spinal premotor network driving scratching flexor and extensor alternation. (2025) 细胞报告. 44(6):115845. DOI: 10.1016/j.celrep.2025.115845

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Goulding, M., Bollu, T., Büschges, A. Sensory Feedback and the Dynamic Control of Movement. (2025) 神经科学年度评论》。. DOI: 10.1146/annurev-neuro-112723-042229

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Chung, B., Zia, M., Thomas, K.A., Michaels, J.A., Jacob, A., Pack, A., Williams, M.J., Nagapudi, K., Teng, L.H., Arrambide, E., Ouellette, L., Oey, N., Gibbs, R., Anschutz, P., Lu, J., Wu, Y., Kashefi, M., Oya, T., Kersten, R., Mosberger, A.C., O'Connell, S., Wang, R., Marques, H., Mendes, A.R., Lenschow, C., Kondakath, G., Kim, J.J., Olson, W., Quinn, K.N., Perkins, P., Gatto, G., Thanawalla, A., Coltman, S., Kim, T., Smith, T., Binder-Markey, B., Zaback, M., Thompson, C.K., Giszter, S., Person, A., Goulding, M., Azim, E., Thakor, N., O'Connor, D., Trimmer, B., Lima, S.Q., Carey, M.R., Pandarinath, C., Costa, R.M., Pruszynski, J.A., Bakir, M., Sober, S.J. Myomatrix arrays for high-definition muscle recording. (2023) Elife. 12. DOI: 10.7554/eLife.88551

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Ren, X., Liu, S., Virlogeux, A., Kang, S.J., Brusch, J., Liu, Y., Dymecki, S.M., Han, S., Goulding, M., Acton, D. Identification of an essential spinoparabrachial pathway for mechanical itch. (2023) 神经元. DOI: 10.1016/j.neuron.2023.03.013

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Hayashi, M., Gullo, M., Senturk, G., Di Costanzo, S., Nagasaki, S.C., Kageyama, R., Imayoshi, I., Goulding, M., Pfaff, S.L., Gatto, G. A spinal synergy of excitatory and inhibitory neurons coordinates ipsilateral body movements. (2023) bioRxiv. DOI: 10.1101/2023.03.21.533603

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Lecoin, L., Dempsey, B., Garancher, A., Bourane, S., Ruffault, P.L., Morin-Surun, M.P., Rocques, N., Goulding, M., Eychène, A., Pouponnot, C., Fortin, G., Champagnat, J. Mafa-dependent GABAergic activity promotes mouse neonatal apneas. (2022) 自然-通讯. 13(1):3284. DOI: 10.1038/s41467-022-30825-3

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Zholudeva, L.V., Abraira, V.E., Satkunendrarajah, K., McDevitt, T.C., Goulding, M.D., Magnuson, D.S.K., Lane, M.A. Spinal Interneurons as Gatekeepers to Neuroplasticity after Injury or Disease. (2021) 神经科学杂志. DOI: 10.1523/JNEUROSCI.1654-20.2020

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Peirs, C., Williams, S.G., Zhao, X., Arokiaraj, C.M., Ferreira, D.W., Noh, M.C., Smith, K.M., Halder, P., Corrigan, K.A., Gedeon, J.Y., Lee, S.J., Gatto, G., Chi, D., Ross, S.E., Goulding, M., Seal, R.P. Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury. (2020) 神经元. DOI: 10.1016/j.neuron.2020.10.027

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Gatto, G., Bourane, S., Ren, X., Di Costanzo, S., Fenton, P.K., Halder, P., Seal, R.P., Goulding, M.D. A Functional Topographic Map for Spinal Sensorimotor Reflexes. (2020) 神经元. DOI: 10.1016/j.neuron.2020.10.003

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Roome, R.B., Bourojeni, F.B., Mona, B., Rastegar-Pouyani, S., Blain, R., Dumouchel, A., Salesse, C., Thompson, W.S., Brookbank, M., Gitton, Y., Tessarollo, L., Goulding, M., Johnson, J.E., Kmita, M., Chédotal, A., Kania, A. Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. (2020) 细胞报告. 33(8):108425. DOI: 10.1016/j.celrep.2020.108425

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Choi, S., Hachisuka, J., Brett, M.A., Magee, A.R., Omori, Y., Iqbal, N.U., Zhang, D., DeLisle, M.M., Wolfson, R.L., Bai, L., Santiago, C., Gong, S., Goulding, M., Heintz, N., Koerber, H.R., Ross, S.E., Ginty, D.D. Parallel ascending spinal pathways for affective touch and pain. [Pubmed] (2020) 自然.:https://rdcu.be/b9ulT DOI: 10.1038/s41586-020-2860-1

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Paixão, S., Loschek, L., Gaitanos, L., Alcalà Morales, P., Goulding, M., Klein, R. Identification of Spinal Neurons Contributing to the Dorsal Column Projection Mediating Fine Touch and Corrective Motor Movements. (2019) 神经元. 104(4):749-764. DOI: 10.1016/j.neuron.2019.08.029

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Acton, D., Ren, X., Di Costanzo, S., Dalet, A., Bourane, S., Bertocchi, I., Eva, C., Goulding, M. Spinal Neuropeptide Y1 Receptor-Expressing Neurons Form an Essential Excitatory Pathway for Mechanical Itch. (2019) 细胞报告. 28(3):625-639.e6. DOI: 10.1016/j.celrep.2019.06.033

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Gatto, G., Smith, K.M., Ross, S.E., Goulding, M. Neuronal diversity in the somatosensory system: bridging the gap between cell type and function. (2019) 当前神经生物学评论. 56:167-174. DOI: 10.1016/j.conb.2019.03.002

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Huang, T., Lin, S.H., Malewicz, N.M., Zhang, Y., Zhang, Y., Goulding, M., LaMotte, R.H., Ma, Q. Identifying the pathways required for coping behaviours associated with sustained pain. (2018) 自然. 565(7737):86-90. DOI: 10.1038/s41586-018-0793-8

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Zhang, Y., Liu, S., Zhang, Y.Q., Goulding, M., Wang, Y.Q., Ma, Q. Timing Mechanisms Underlying Gate Control by Feedforward Inhibition. (2018) 神经元. 99(5):941-955.e4. DOI: 10.1016/j.neuron.2018.07.026

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Ueno, M., Nakamura, Y., Li, J., Gu, Z., Niehaus, J., Maezawa, M., Crone, S.A., Goulding, M., Baccei, M.L., Yoshida, Y. Corticospinal Circuits from the Sensory and Motor Cortices Differentially Regulate Skilled Movements through Distinct Spinal Interneurons. (2018) 细胞报告. 23(5):1286-1300.e7. DOI: 10.1016/j.celrep.2018.03.137

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Gatto, G., Goulding, M. Locomotion Control: Brainstem Circuits Satisfy the Need for Speed. (2018) 当前生物学。. 28(6):R256-R259. DOI: 10.1016/j.cub.2018.01.068

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Koch, S.C., Del Barrio, M.G., Dalet, A., Gatto, G., Günther, T., Zhang, J., Seidler, B., Saur, D., Schüle, R., Goulding, M. RORβ Spinal Interneurons Gate Sensory Transmission during Locomotion to Secure a Fluid Walking Gait. (2017) 神经元. DOI: 10.1016/j.neuron.2017.11.011

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Wu, J., Capelli, P., Bouvier, J., Goulding, M., Arber, S., Fortin, G. A V0 core neuronal circuit for inspiration. (2017) 自然-通讯. 8(1):544. DOI: 10.1038/s41467-017-00589-2

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Koch, S.C., Acton, D., Goulding, M. Spinal Circuits for Touch, Pain, and Itch. (2017) Annual Review of Physiology. DOI: 10.1146/annurev-physiol-022516-034303

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Cheng, L., Duan, B., Huang, T., Zhang, Y., Chen, Y., Britz, O., Garcia-Campmany, L., Ren, X., Vong, L., Lowell, B.B., Goulding, M., Wang, Y., Ma, Q. Identification of spinal circuits involved in touch-evoked dynamic mechanical pain. (2017) 自然神经科学. 20(6):804-814. DOI: 10.1038/nn.4549

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Flynn, J.R., Conn, V.L., Boyle, K.A., Hughes, D.I., Watanabe, M., Velasquez, T., Goulding, M.D., Callister, R.J., Graham, B.A. Anatomical and Molecular Properties of Long Descending Propriospinal Neurons in Mice. (2017) Frontiers in Neuroanatomy. 11:5. DOI: 10.3389/fnana.2017.00005

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Sternfeld, M.J., Hinckley, C.A., Moore, N.J., Pankratz, M.T., Hilde, K.L., Driscoll, S.P., Hayashi, M., Amin, N.D., Bonanomi, D., Gifford, W.D., Sharma, K., Goulding, M., Pfaff, S.L. Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells. (2017) Elife. 6. DOI: 10.7554/eLife.21540

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Tuncdemir, S.N., Wamsley, B., Stam, F.J., Osakada, F., Goulding, M., Callaway, E.M., Rudy, B., Fishell, G. Early Somatostatin Interneuron Connectivity Mediates the Maturation of Deep Layer Cortical Circuits. (2016) 神经元. 89(3):521-35. DOI: 10.1016/j.neuron.2015.11.020

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Bourane, S., Duan, B., Koch, S.C., Dalet, A., Britz, O., Garcia-Campmany, L., Kim, E., Cheng, L., Ghosh, A., Ma, Q., Goulding, M. Gate control of mechanical itch by a subpopulation of spinal cord interneurons. (2015) 科学. 350(6260):550-4. DOI: 10.1126/science.aac8653

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Britz, O., Zhang, J., Grossmann, K.S., Dyck, J., Kim, J.C., Dymecki, S., Gosgnach, S., Goulding, M. A genetically defined asymmetry underlies the inhibitory control of flexor-extensor locomotor movements. (2015) Elife. 4. DOI: 10.7554/eLife.04718

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Mukherjee, S., Hsieh, W.L., Smith, N., Goulding, M., Heikenfeld, J. Electrokinetic pixels with biprimary inks for color displays and color-temperature-tunable smart windows. (2015) Appl Opt. 54(17):5603-5609.

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Bourane, S., Grossmann, K.S., Britz, O., Dalet, A., Del Barrio, M.G., Stam, F.J., Garcia-Campmany, L., Koch, S., Goulding, M. Identification of a spinal circuit for light touch and fine motor control. (2015) 牢房. 160(3):503-15. DOI: 10.1016/j.cell.2015.01.011

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Duan, B., Cheng, L., Bourane, S., Britz, O., Padilla, C., Garcia-Campmany, L., Krashes, M., Knowlton, W., Velasquez, T., Ren, X., Ross, S., Lowell, B.B., Wang, Y., Goulding, M., Ma, Q. Identification of spinal circuits transmitting and gating mechanical pain. (2014) 牢房. 159(6):1417-1432. DOI: 10.1016/j.cell.2014.11.003

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Carcagno, A.L., Di Bella, D.J., Goulding, M., Guillemot, F., Lanuza, G.M. Neurogenin3 restricts serotonergic neuron differentiation to the hindbrain. (2014) 神经科学杂志. 34(46):15223-33. DOI: 10.1523/JNEUROSCI.3403-14.2014

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Hatori, M., Gill, S., Mure, L.S., Goulding, M., O'Leary, D.D., Panda, S. Lhx1 maintains synchrony among circadian oscillator neurons of the SCN. (2014) Elife. 3:e03357. DOI: 10.7554/eLife.03357

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Goulding, M., Bourane, S., Garcia-Campmany, L., Dalet, A., Koch, S. Inhibition downunder: an update from the spinal cord. (2014) 当前神经生物学评论. 26:161-6. DOI: 10.1016/j.conb.2014.03.006

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Zhang, J., Lanuza, G.M., Britz, O., Wang, Z., Siembab, V.C., Zhang, Y., Velasquez, T., Alvarez, F.J., Frank, E., Goulding, M. V1 and v2b interneurons secure the alternating flexor-extensor motor activity mice require for limbed locomotion. (2014) 神经元. 82(1):138-50. DOI: 10.1016/j.neuron.2014.02.013

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Borowska, J., Jones, C.T., Zhang, H., Blacklaws, J., Goulding, M., Zhang, Y. Functional subpopulations of V3 interneurons in the mature mouse spinal cord. (2013) 神经科学杂志. 33(47):18553-65. DOI: 10.1523/JNEUROSCI.2005-13.2013

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Del Barrio, M.G., Bourane, S., Grossmann, K., Schüle, R., Britsch, S., O'Leary, D.D., Goulding, M. A transcription factor code defines nine sensory interneuron subtypes in the mechanosensory area of the spinal cord. (2013) PLOS One. 8(11):e77928. DOI: 10.1371/journal.pone.0077928

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Francius, C., Harris, A., Rucchin, V., Hendricks, T.J., Stam, F.J., Barber, M., Kurek, D., Grosveld, F.G., Pierani, A., Goulding, M., Clotman, F. Identification of multiple subsets of ventral interneurons and differential distribution along the rostrocaudal axis of the developing spinal cord. (2013) PLOS One. 8(8):e70325. DOI: 10.1371/journal.pone.0070325

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Li, Y., Stam, F.J., Aimone, J.B., Goulding, M., Callaway, E.M., Gage, F.H. Molecular layer perforant path-associated cells contribute to feed-forward inhibition in the adult dentate gyrus. (2013) 美国国家科学院院刊. 110(22):9106-11. DOI: 10.1073/pnas.1306912110

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Goulding, M. Motor neurons that multitask. (2012) 神经元. 76(4):669-70. DOI: 10.1016/j.neuron.2012.11.011

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Stam, F.J., Hendricks, T.J., Zhang, J., Geiman, E.J., Francius, C., Labosky, P.A., Clotman, F., Goulding, M. Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program. (2012) Development. 139(1):179-90. DOI: 10.1242/dev.071134

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Ikrar, T., Shi, Y., Velasquez, T., Goulding, M., Xu, X. Cell-type specific regulation of cortical excitability through the allatostatin receptor system. (2012) Front Neural Circuits. 6:2. DOI: 10.3389/fncir.2012.00002

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Grossmann, K.S., Giraudin, A., Britz, O., Zhang, J., Goulding, M. Genetic dissection of rhythmic motor networks in mice. (2010) Progress in Brain Research. 187:19-37. DOI: 10.1016/B978-0-444-53613-6.00002-2

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Garcia-Campmany, L., Stam, F.J., Goulding, M. From circuits to behaviour: motor networks in vertebrates. (2010) 当前神经生物学评论. 20(1):116-25. DOI: 10.1016/j.conb.2010.01.002

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Lin, W., Metzakopian, E., Mavromatakis, Y.E., Gao, N., Balaskas, N., Sasaki, H., Briscoe, J., Whitsett, J.A., Goulding, M., Kaestner, K.H., Ang, S.L. Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development. (2009) Developmental Biology. 333(2):386-96. DOI: 10.1016/j.ydbio.2009.07.006

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Goulding, M. Circuits controlling vertebrate locomotion: moving in a new direction. (2009) Nature Reviews Neuroscience. 10(7):507-18. DOI: 10.1038/nrn2608

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Zhang, Y., Narayan, S., Geiman, E., Lanuza, G.M., Velasquez, T., Shanks, B., Akay, T., Dyck, J., Pearson, K., Gosgnach, S., Fan, C.M., Goulding, M. V3 spinal neurons establish a robust and balanced locomotor rhythm during walking. (2008) 神经元. 60(1):84-96. DOI: 10.1016/j.neuron.2008.09.027

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Pagliardini, S., Ren, J., Gray, P.A., Vandunk, C., Gross, M., Goulding, M., Greer, J.J. Central respiratory rhythmogenesis is abnormal in lbx1- deficient mice. (2008) 神经科学杂志. 28(43):11030-41. DOI: 10.1523/JNEUROSCI.1648-08.2008

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Wang, Z., Li, L., Goulding, M., Frank, E. Early postnatal development of reciprocal Ia inhibition in the murine spinal cord. (2008) Journal of Neurophysiology. 100(1):185-96. DOI: 10.1152/jn.90354.2008

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Xu, Y., Lopes, C., Qian, Y., Liu, Y., Cheng, L., Goulding, M., Turner, E.E., Lima, D., Ma, Q. Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons. (2008) 神经科学杂志. 28(15):4037-46. DOI: 10.1523/JNEUROSCI.4126-07.2008

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Pillai, A., Mansouri, A., Behringer, R., Westphal, H., Goulding, M. Lhx1 and Lhx5 maintain the inhibitory-neurotransmitter status of interneurons in the dorsal spinal cord. (2007) Development. 134(2):357-66. DOI: 10.1242/dev.02717

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Tan, E.M., Yamaguchi, Y., Horwitz, G.D., Gosgnach, S., Lein, E.S., Goulding, M., Albright, T.D., Callaway, E.M. Selective and quickly reversible inactivation of mammalian neurons in vivo using the Drosophila allatostatin receptor. (2006) 神经元. 51(2):157-70. DOI: 10.1016/j.neuron.2006.06.018

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Mizuguchi, R., Kriks, S., Cordes, R., Gossler, A., Ma, Q., Goulding, M. Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons. (2006) 自然神经科学. 9(6):770-8. DOI: 10.1038/nn1706

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Gosgnach, S., Lanuza, G.M., Butt, S.J., Saueressig, H., Zhang, Y., Velasquez, T., Riethmacher, D., Callaway, E.M., Kiehn, O., Goulding, M. V1 spinal neurons regulate the speed of vertebrate locomotor outputs. (2006) 自然. 440(7081):215-9. DOI: 10.1038/nature04545

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Nakahira, E., Kagawa, T., Shimizu, T., Goulding, M.D., Ikenaka, K. Direct evidence that ventral forebrain cells migrate to the cortex and contribute to the generation of cortical myelinating oligodendrocytes. (2006) Developmental Biology. 291(1):123-31. DOI: 10.1016/j.ydbio.2005.12.010

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Quina, L.A., Pak, W., Lanier, J., Banwait, P., Gratwick, K., Liu, Y., Velasquez, T., O'Leary, D.D., Goulding, M., Turner, E.E. Brn3a-expressing retinal ganglion cells project specifically to thalamocortical and collicular visual pathways. (2005) 神经科学杂志. 25(50):11595-604. DOI: 10.1523/JNEUROSCI.2837-05.2005

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Alvarez, F.J., Jonas, P.C., Sapir, T., Hartley, R., Berrocal, M.C., Geiman, E.J., Todd, A.J., Goulding, M. Postnatal phenotype and localization of spinal cord V1 derived interneurons. (2005) 神经科学杂志. 493(2):177-92. DOI: 10.1002/cne.20711

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Cheng, L., Samad, O.A., Xu, Y., Mizuguchi, R., Luo, P., Shirasawa, S., Goulding, M., Ma, Q. Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes. (2005) 自然神经科学. 8(11):1510-5. DOI: 10.1038/nn1569

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Kriks, S., Lanuza, G.M., Mizuguchi, R., Nakafuku, M., Goulding, M. Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord. (2005) Development. 132(13):2991-3002. DOI: 10.1242/dev.01878

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Goulding, M., Pfaff, S.L. Development of circuits that generate simple rhythmic behaviors in vertebrates. (2005) 当前神经生物学评论. 15(1):14-20. DOI: 10.1016/j.conb.2005.01.017

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Goulding, M. How early is firing required for wiring? (2004) 神经元. 43(5):601-3. DOI: 10.1016/j.neuron.2004.08.027

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Goulding, M. Neurobiology: a matter of balance. (2004) 自然. 429(6991):515-7. DOI: 10.1038/429515a


Lanuza, G.M., Gosgnach, S., Pierani, A., Jessell, T.M., Goulding, M. Genetic identification of spinal interneurons that coordinate left-right locomotor activity necessary for walking movements. (2004) 神经元. 42(3):375-86.

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Cheng, L., Arata, A., Mizuguchi, R., Qian, Y., Karunaratne, A., Gray, P.A., Arata, S., Shirasawa, S., Bouchard, M., Luo, P., Chen, C.L., Busslinger, M., Goulding, M., Onimaru, H., Ma, Q. Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. (2004) 自然神经科学. 7(5):510-7. DOI: 10.1038/nn1221

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Sapir, T., Geiman, E.J., Wang, Z., Velasquez, T., Mitsui, S., Yoshihara, Y., Frank, E., Alvarez, F.J., Goulding, M. Pax6 and engrailed 1 regulate two distinct aspects of renshaw cell development. (2004) 神经科学杂志. 24(5):1255-64. DOI: 10.1523/JNEUROSCI.3187-03.2004

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Goulding, M., Lanuza, G., Sapir, T., Narayan, S. The formation of sensorimotor circuits. (2002) 当前神经生物学评论. 12(5):508-15.

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Gross, M.K., Dottori, M., Goulding, M. Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord. (2002) 神经元. 34(4):535-49.

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Dottori, M., Gross, M.K., Labosky, P., Goulding, M. The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate. (2001) Development. 128(21):4127-38.

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Nicholson, L.F., Ma, L., Goulding, M. Cloning and expression of Munc 30: a member of the paired -like homeodomain gene family. (2001) Cell Biology International. 25(4):351-65. DOI: 10.1006/cbir.2000.0638

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Simon, H.H., Saueressig, H., Wurst, W., Goulding, M.D., O'Leary, D.D. Fate of midbrain dopaminergic neurons controlled by the engrailed genes. (2001) 神经科学杂志. 21(9):3126-34.

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Lamar, E., Kintner, C., Goulding, M. Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation. (2001) Development. 128(8):1335-46.

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Moran-Rivard, L., Kagawa, T., Saueressig, H., Gross, M.K., Burrill, J., Goulding, M. Evx1 is a postmitotic determinant of v0 interneuron identity in the spinal cord. (2001) 神经元. 29(2):385-99.

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Pierani, A., Moran-Rivard, L., Sunshine, M.J., Littman, D.R., Goulding, M., Jessell, T.M. Control of interneuron fate in the developing spinal cord by the progenitor homeodomain protein Dbx1. (2001) 神经元. 29(2):367-384.

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Goulding, M., Lamar, E. Neuronal patterning: Making stripes in the spinal cord. (2000) 当前生物学。. 10(15):565-568.


Mah, S.P., Saueressig, H., Goulding, M., Kintner, C., Dressler, G.R. Kidney development in cadherin-6 mutants: delayed mesenchyme-to-epithelial conversion and loss of nephrons. (2000) Developmental Biology. 223(1):38-53. DOI: 10.1006/dbio.2000.9738

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Gross, M.K., Moran-Rivard, L., Velasquez, T., Nakatsu, M.N., Jagla, K., Goulding, M. Lbx1 is required for muscle precursor migration along a lateral pathway into the limb. (2000) Development. 127(2):413-424.

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Saueressig, H., Burrill, J., Goulding, M. Engrailed-1 and netrin-1 regulate axon pathfinding by association interneurons that project to motor neurons. (1999) Development. 126(19):4201-4212.

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Bang, A.G., Papalopulu, N., Goulding, M.D., Kintner, C. Expression of Pax-3 in the lateral neural plate is dependent on a Wnt-mediated signal from posterior nonaxial mesoderm. (1999) Developmental Biology. 212(2):366-80. DOI: 10.1006/dbio.1999.9319

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Goulding, M. Specifying motor neurons and their connections. (1998) 神经元. 21(5):943-946.


Burrill, J.D., Moran, L., Goulding, M.D., Saueressig, H. PAX2 is expressed in multiple spinal cord interneurons, including a population of EN1+ interneurons that require PAX6 for their development. (1997) Development. 124(22):4493-4503.

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McWhirter, J.R., Goulding, M., Weiner, J.A., Chun, J., Murre, C. A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1. (1997) Development. 124(17):3221-3232.

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Bang, A.G., Papalopulu, N., Kintner, C., Goulding, M.D. Expression of Pax-3 is initiated in the early neural plate by posteriorizing signals produced by the organizer and by posterior non-axial mesoderm. (1997) Development. 124(10):2075-85.

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Maroto, M., Reshef, R., Münsterberg, A.E., Koester, S., Goulding, M., Lassar, A.B. Ectopic Pax-3 activates MyoD and Myf-5 expression in embryonic mesoderm and neural tissue. (1997) 牢房. 89(1):139-148.

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Daston, G., Lamar, E., Olivier, M., Goulding, M. Pax-3 is necessary for migration but not differentiation of limb muscle precursors in the mouse. (1996) Development. 122(3):1017-1027.

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Bang, A.G., Goulding, M.D. Regulation of vertebrate neural cell fate by transcription factors. (1996) 当前神经生物学评论. 6(1):25-32.

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Kilpatrick, T.J., Brown, A., Lai, C., Gassmann, M., Goulding, M., Lemke, G. Expression of the Tyro4/Mek4/Cek4 gene specifically marks a subset of embryonic motor neurons and their muscle targets. (1996) Molecular and Cellular Neurosciences. 7(1):62-74. DOI: 10.1006/mcne.1996.0005

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Goulding, M., Lumsden, A., Paquette, A.J. Regulation of Pax-3 expression in the dermomyotome and its role in muscle development. (1994) Development. 120(4):957-971.

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Chalepakis, G., Goulding, M., Read, A., Strachan, T., Gruss, P. Molecular basis of splotch and Waardenburg Pax-3 mutations. (1994) 美国国家科学院院刊. 91(9):3685-3689.

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Goulding, M., Paquette, A. Pax genes and neural tube defects in the mouse. (1994) Ciba Found. Symp. 181:103-113; discussion 113-117.

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Goulding, M., Sterrer, S., Fleming, J., Balling, R., Nadeau, J., Moore, K.J., Brown, S.D., Steel, K.P., Gruss, P. Analysis of the Pax-3 gene in the mouse mutant splotch. (1993) Genomics. 17(2):355-363. DOI: 10.1006/geno.1993.1332

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Goulding, M.D., Lumsden, A., Gruss, P. Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord. (1993) Development. 117(3):1001-1016.

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Chowdhury, K., Goulding, M., Walther, C., Imai, K., Fickenscher, H. The ubiquitous transactivator Zfp-38 is upregulated during spermatogenesis with differential transcription. (1992) Mech. Dev. 39(3):129-42.

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Walther, C., Guenet, J.L., Simon, D., Deutsch, U., Jostes, B., Goulding, M.D., Plachov, D., Balling, R., Gruss, P. Pax: a murine multigene family of paired box-containing genes. (1991) Genomics. 11(2):424-434.

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Chalepakis, G., Fritsch, R., Fickenscher, H., Deutsch, U., Goulding, M., Gruss, P. The molecular basis of the undulated/Pax-1 mutation. (1991) 牢房. 66(5):873-884.

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Goulding, M.D., Chalepakis, G., Deutsch, U., Erselius, J.R., Gruss, P. Pax-3, a novel murine DNA binding protein expressed during early neurogenesis. (1991) EMBO 期刊. 10(5):1135-1147.

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Erselius, J.R., Goulding, M.D., Gruss, P. Structure and expression pattern of the murine Hox-3.2 gene. (1990) Development. 110(2):629-642.

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Hatzopoulos, A.K., Stoykova, A.S., Erselius, J.R., Goulding, M., Neuman, T., Gruss, P. Structure and expression of the mouse Oct2a and Oct2b, two differentially spliced products of the same gene. (1990) Development. 109(2):349-362.

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Dragunow, M., Goulding, M., Faull, R.L., Ralph, R., Mee, E., Frith, R. Induction of c-fos mRNA and protein in neurons and glia after traumatic brain injury: pharmacological characterization. (1990) Exp. Neurol. 107(3):236-248.

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Goulding, M.D., Gruss, P. The homeobox in vertebrate development. (1989) 细胞生物学进展. 1(6):1088-93.


Dragunow, M., Abraham, W.C., Goulding, M., Mason, S.E., Robertson, H.A., Faull, R.L. Long-term potentiation and the induction of c-fos mRNA and proteins in the dentate gyrus of unanesthetized rats. (1989) Neurosci. Lett. 101(3):274-80.

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Goulding, M.D., Ralph, R.K. Cyclic-AMP-induced c-fos expression and its relevance to differentiation of a transformed mast cell line. (1989) Biochimica et Biophysica Acta. 1007(1):99-108.

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Goulding, M., Ralph, R.K. Cyclic AMP, nuclear protein kinase and the PY815 cell cycle. (1985) Molecular and Cellular Biochemistry. 67(1):31-8.

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教育

MS (Honors) Cell Biology, University of Auckland, Nz
PhD, Cellular and Molecular Biology, University of Auckland, Nz
Postdoctoral Fellow, Max Planck Institute for Biophysical Chemistry, Germany


奖项与荣誉

  • American Academy of Arts & Sciences, 2024
  • Brain Prize, 2022
  • NINDS R35 Outstanding Investigator Award, 2019
  • Javits Neuroscience Investigator Award, 2006
  • Pew Scholar, 1994-1998
  • Basil O'Connor Research Award, 1993-1995