助理教授
NOMIS 免疫生物学和微生物致病机理中心
William Scandling Developmental Chair
Jaquish, A., Ramanan, D. Got milk? how T cells shape lactation and beyond. (2026) Trends in Immunology. DOI: 10.1016/j.it.2026.01.007
Frascoli, M., Nicholas, D., Weinstock, A., Hsu, C.L., Dongre, A., Osterhout, J.A., Globig, A.M., Ramanan, D., Therrien, M., McCubbrey, A. Women in STEM becoming independent: Asking for help creates opportunities for connections and kindness. (2025) 实验医学杂志. 222(10). DOI: 10.1084/jem.20251668
Jaquish, A., Phung, E., Gong, X., Baldominos, P., Galván-Peña, S., Magill, I., Bursulaya, I., Marina, E., , Bertrand, K., Chambers, C., Muñoz-Rojas, A.R., Agudo, J., Mathis, D., Benoist, C., Ramanan, D. Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis. (2025) Nature Immunology. 26(8):1411-1422. DOI: 10.1038/s41590-025-02218-3
Wong, S.Y., Estevinho, M.M., Heaney, T., Marshall, A.A., Giselbrecht, E., Daniel, S.G., Zhou, C., Rosas-Villegas, A., Jang, K.K., Yang, H., Mabel Ko, H., Paulson, J.D., Ding, Y., Bittinger, K., Cho, J.H., Lewis, J.D., Ramanan, D., Cadwell, K. Goblet cell loss linked to NOD2 and secondary resection in Crohn's disease is induced by dysbiosis and epithelial MyD88. (2025) Cell Mol Gastroenterol Hepatol.:101533 DOI: 10.1016/j.jcmgh.2025.101533
Jaquish, A., Phung, E., Gong, X., Baldominos-Flores, P., Galvan-Pena, S., Bursulaya, I., Magill, I., , Bertrand, K., Chambers, C., Agudo, J., Mathis, D., Benoist, C., Ramanan, D. Expansion of mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis. (2024) bioRxiv. DOI: 10.1101/2024.07.09.602739
Ramanan, D., Chowdhary, K., Candéias, S.M., Sassone-Corsi, M., Gelineau, A., Mathis, D., Benoist, C. Homeostatic, repertoire and transcriptional relationships between colon T regulatory cell subsets. (2023) 美国国家科学院院刊. 120(50):e2311566120. DOI: 10.1073/pnas.2311566120
Ramanan, D., Pratama, A., Zhu, Y., Venezia, O., Sassone-Corsi, M., Chowdhary, K., Galván-Peña, S., Sefik, E., Brown, C., Gélineau, A., Mathis, D., Benoist, C. Regulatory T cells in the face of the intestinal microbiota. (2023) Nature Reviews. Immunology. DOI: 10.1038/s41577-023-00890-w
Ramanan, D., Chowdhary, K., Candéias, S.M., Sassone-Corsi, M., Mathis, D., Benoist, C. Homeostatic, repertoire and transcriptional relationships between colon T regulatory cell subsets. (2023) bioRxiv. DOI: 10.1101/2023.05.17.541199
Wu, M., Zheng, W., Song, X., Bao, B., Wang, Y., Ramanan, D., Yang, D., Liu, R., Macbeth, J.C., Do, E.A., Andrade, W.A., Yang, T., Cho, H.S., Gazzaniga, F.S., Ilves, M., Coronado, D., Thompson, C., Hang, S., Chiu, I.M., Moffitt, J.R., Hsiao, A., Mekalanos, J.J., Benoist, C., Kasper, D.L. Microbiome induced complement synthesized in the gut protects against enteric infections. (2023) bioRxiv. DOI: 10.1101/2023.02.02.523770
Sassone-Corsi, M., Azriel, S., Simon, A., Ramanan, D., Ortiz-Lopez, A., Chen, F., Yissachar, N., Mathis, D., Benoist, C. Sequestration of gut pathobionts in intraluminal casts, a mechanism to avoid dysregulated T cell activation by pathobionts. (2022) 美国国家科学院院刊. 119(41):e2209624119. DOI: 10.1073/pnas.2209624119
Yan, Y., Ramanan, D., Rozenberg, M., McGovern, K., Rastelli, D., Vijaykumar, B., Yaghi, O., Voisin, T., Mosaheb, M., Chiu, I., Itzkovitz, S., Rao, M., Mathis, D., Benoist, C. Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut. (2021) Immunity. 54(3):499-513.e5. DOI: 10.1016/j.immuni.2021.02.002
Ramanan, D., Sefik, E., Galván-Peña, S., Wu, M., Yang, L., Yang, Z., Kostic, A., Golovkina, T.V., Kasper, D.L., Mathis, D., Benoist, C. An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint. (2020) 牢房. 181(6):1276-1290.e13. DOI: 10.1016/j.cell.2020.04.030
Wong, S.Y., Coffre, M., Ramanan, D., Hines, M.J., Gomez, L.E., Peters, L.A., Schadt, E.E., Koralov, S.B., Cadwell, K. B Cell Defects Observed in Knockout Mice Are a Consequence of a Mutation Frequently Found in Inbred Strains. (2018) Journal of immunology. 201(5):1442-1451. DOI: 10.4049/jimmunol.1800014
Ramanan, D., Bowcutt, R., Lee, S.C., Tang, M.S., Kurtz, Z.D., Ding, Y., Honda, K., Gause, W.C., Blaser, M.J., Bonneau, R.A., Lim, Y.A., Loke, P., Cadwell, K. Helminth infection promotes colonization resistance via type 2 immunity. (2016) 科学. 352(6285):608-12. DOI: 10.1126/science.aaf3229
Ramanan, D., Cadwell, K. Intrinsic Defense Mechanisms of the Intestinal Epithelium. (2016) 细胞宿主与微生物. 19(4):434-41. DOI: 10.1016/j.chom.2016.03.003
Marchiando, A.M., Ramanan, D., Ding, Y., Gomez, L.E., Hubbard-Lucey, V.M., Maurer, K., Wang, C., Ziel, J.W., van Rooijen, N., Nuñez, G., Finlay, B.B., Mysorekar, I.U., Cadwell, K. A deficiency in the autophagy gene Atg16L1 enhances resistance to enteric bacterial infection. (2013) 细胞宿主与微生物. 14(2):216-24. DOI: 10.1016/j.chom.2013.07.013
Zhang, Z., Wu, Y., Wang, Z., Dunning, F.M., Rehfuss, J., Ramanan, D., Chapman, E.R., Jackson, M.B. Release mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cells. (2011) Molecular Biology of the Cell. 22(13):2324-36. DOI: 10.1091/mbc.E11-02-0159
哈佛医学院博士后研究员
PhD, Immunology and Inflammation, New York University
BS, Cell and Molecular Biology, Winona State University