December 19, 2016

Salk Institute hires star scientists in plant biology and cancer research

索尔克新闻


Salk Institute hires star scientists in plant biology and cancer research

LA JOLLA—The Salk Institute is pleased to welcome 沃尔夫冈·布施 as an associate professor and Edward Stites as an assistant professor, leaders of plant sciencecancer research, respectively.

“Salk’s mission to conduct groundbreaking research on some of humanity’s most critical environmental and disease-related issues will take a great leap forward with the addition of these two exceptional scientists,” says Salk President 伊丽莎白·布莱克本. “Their expertise will advance Salk’s crucial work in plant biology—needed now more than ever in the face of climate change—as well as in the devastating disease of cancer.”

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沃尔夫冈·布施

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Busch, whose appointment begins on March 31, 2017, joins the Institute as an associate professor in the Plant Molecular and Cellular Biology Laboratory. Busch uses a systems genetics approach—which combines techniques from genetics, genomics and other science fields—to understand how root growth in given environments is determined by a plant’s genes. Discoveries in this area could reveal critical insight into growing plants (and food) that can thrive in more extreme environments prompted by climate change, such as drought. He focuses mainly on 拟南芥, a commonly studied weed that grows all over the world, to understand, model and predict the molecular and cellular mechanisms responsible for root growth.

Busch comes to Salk from the Gregor Mendel Institute of Molecular Plant Biology, where he was a group leader. He is a recipient of the Society for Experimental Biology President’s Medal, which is awarded to young scientists of outstanding merit. He earned his PhD summa cum laude from the University of Tubingen, in Germany.

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Edward Stites

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“What is really extraordinary about Salk is how much real communication goes on between scientists in different fields,” says Busch. “At many institutions that’s not the case, but this environment lets you step out of your own field and think about really big, fundamental questions. For example, as a plant biologist, being able to talk to neuroscientists about information processing, which both fields deal with, is very exciting.”

Also joining Salk’s faculty is Edward Stites, who will be an assistant professor in the Integrative Biology Laboratory in January 2017. He is a physician-scientist who studies key cellular proteins that usher signals into the cell nucleus from outside the cell, affecting gene expression. When such proteins are dysfunctional, they can trigger uncontrolled growth, which is one of the hallmarks of cancer. By using both traditional experimental techniques and computational ones, Stites aims to develop a new generation of precision therapies that can better target cancers.

“Salk has a history of fostering and nurturing creative, innovative approaches that enable people to make big advances,” says Stites. “This environment will let me maintain all the strengths of being a physician-scientist by connecting with the Salk and UC San Diego cancer centers to know where the biggest questions are, while at the same time being free to pursue my research.”

Prior to joining the Salk Institute, Stites was a clinical pathology resident in the Physician Scientist Training Program at Washington University in St. Louis, Mo. He received both his MD and PhD degrees from the University of Virginia in Charlottesville, obtaining his doctorate in biophysics as part of the Medical Scientist Training Program. His research was recognized with the University of Virginia’s Michael J. Peach award.

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萨尔克生物学研究所

萨尔克研究所是一个独立的非营利性研究机构,由首个安全有效的脊髓灰质炎疫苗的研发者乔纳斯·索尔克于1960年创立。该研究所的使命是推动以合作、敢于冒险为特点的基础性研究,以应对癌症、阿尔茨海默病和农业脆弱性等社会最紧迫的挑战。这项基础科学支撑着所有的转化研究,产生有助于全球新药和创新的见解。.