Janelle Ayres, doctora

Profesor

Salk Institute Legacy Chair

Areas of interest: inflammation and pathobionts in the gut microbiota

Disease models: pathobionts, colorectal cancer

Adam Bowman, PhD

Becario Salk

Areas of interest: Biophotonics, Computational Biology, Neurobiology, Systems Biology

Disease models: cancer, neurology

Jesse Dixon, MD, PhD

Profesor Asociado

Areas of interest: 3d genomic control

Disease models: pediatric leukemia, colon cancer

Joseph Ecker, doctor

Profesor

Salk International Council Chair in Genetics

Areas of interest: epigenomics of stem cells and cancer cells

Disease models: breast cancer

Dannielle Engle, PhD

Profesor adjunto

Laboratorio de Biología Reguladora

Helen McLoraine Developmental Chair in Neurobiology

Areas of interest: organoid technology, glycosylation in cancer, early detection/treatment, mouse models

Disease models: pancreatic cancer, pancreatitis

Ronald Evans, doctor

Profesor y director

March of Dimes Chair in Molecular and Developmental Biology

Areas of interest: nuclear receptor function in metabolism and cancer

Disease models: pancreatic cancer, colon cancer, diabetes

Rusty Gage, doctor

Profesor

Laboratorio de Genética

Vi and John Adler Chair for Research on Age-Related Neurodegenerative Disease

Areas of interest: neurogenesis, adult stem cells, iPSCs

Disease models: human aging and age-associated diseases

Diana Hargreaves, PhD

Profesor

Areas of interest: BAF chromatin remodeling complex and the role of chromatin regulators in cancer

Disease models: BAF subunit mutant solid tumors such as medulloblastomas

Daniel Hollern, Doctor en Filosofía

Profesor adjunto

Areas of interest: triple-negative breast cancer, immune cell dynamics, functional genomics

Disease models: breast cancer

Tony Hunter, PhD

Profesor de la American Cancer Society

Renato Dulbecco Chair

Areas of interest: phosphorylation, ubiquitylation and sumoylation in cancer

Disease models: cancer kinome, pancreatic cancer, glioblastoma, prostate cancer

Dr. Gerald Joyce, médico y doctor en Medicina

Presidente

Profesor

Centro Jack H. Skirball de Biología Química y Proteómica

Areas of interest: RNA evolution, RNA biology

Disease models: high throughput screening and development of small molecules and biologic therapeutics

Susan Kaech, Doctora en Filosofía

Profesor

Areas of interest: T cell function, tumor immunology

Disease models: immune checkpoint inhibitors in model systems

Jan Karlseder, PhD

Vicepresidente, Director Científico

Profesor

Donald and Darlene Shiley Chair

Areas of interest: telomere function and dysregulation in cancer cells

Disease models: combined treatment of cancer with mitotic inhibitors (Taxol, Velcade and Vinblastine) and PARP inhibitors

Agnieszka Kendrick, PhD

Profesor adjunto

Laboratorio de Biología Molecular y Celular

Areas of interest: Alzheimer's disease, molecular motors

Disease models: colon/pancreatic cancer

Pallav Kosuri, doctor

Profesor adjunto

Laboratorio de Biología Integrativa

Areas of interest: DNA topography, RNA transcriptomics, chromatin

Disease models: mechanical and cellular architecture

Julie Law, doctora

Profesor Asociado

Laboratorio de Biología Molecular y Celular Vegetal

Areas of interest: DNA methylation; epigenome in both agriculture and human health

Disease models: Arabidopsis thaliana

Dmitry Lyumkis, PhD

Profesor Asociado

Presidencia de Desarrollo de las Fundaciones Hearst

Areas of interest: decoding structures of macromolecular assembly using CryoEMDisease models: cancer, inflammation

Disease models: cancer, inflammation

Graham McVicker, Doctor en Filosofía

Profesor Asociado

Areas of interest: human genetic variation impacting immune system and cancer

Disease models: leukemias, pediatric blood cancers

Christian Metallo, doctor

Profesor

Daniel and Martina Lewis Chair

Areas of interest: systems-based modeling to study metabolic regulation/flux in cells, tissues, and animals; stable isotope tracers

Disease models: cancer metabolism, metabolic syndrome and obesity, stem cell biology

Joseph Noel, doctor en filosofía

Profesor y director

Arthur and Julie Woodrow Chair

Areas of interest: biosynthetic enzyme engineering

Disease models: anti-cancer agents

Clodagh O'Shea, PhD

Profesor

Wicklow Chair

Areas of interest: oncolytic adenoviruses, adenovirus genome engineering and E4-ORF3 function

Disease models: tumor-selective oncolytic viral therapy

Satchidananda Panda, doctor

Profesor

Rita and Richard Atkinson Chair

Areas of interest: circadian rhythms and metabolism

Disease models: colon, endometrial, breast and liver cancer

Talmo Pereira, doctor

Becario Salk

Areas of interest: machine learning, animal behavior

Disease models: motor control, single cell states throughout development and disease

Samuel Pfaff, doctor

Profesor

Benjamin H. Lewis Chair

Areas of interest: signaling principles that control specification/connectivity of spinal neurons in locomotion

Disease models: post-polio syndrome

Deepshika Ramanan, PhD

Profesor adjunto

Centro NOMIS de Inmunobiología y Patogénesis Microbiana

Areas of interest: mammary-entero axis; host-microbe interactions; multigenerational immune transfer

Disease models: human tissue samples, breast milk, mouse models

Alan Saghatelian, Doctor en Filosofía

Profesor

Dr. Frederik Paulsen Chair

Areas of interest: mass spectrometry strategies for detection of metabolites and peptides

Disease models: global lipid and peptide profiling of cancer (colon, lung cancer) and metabolic diseases

Gerald Shadel, doctor

Profesor

Cátedra Audrey Geisel en Ciencias Biomédicas

Areas of interest: role of mitochondria in disease, aging, and immune function

Disease models: mitochondrial function in different cancers and neurodegenerative disorders

Reuben Shaw, doctor

Profesor

William R. Brody Chair

Areas of interest: metabolic changes and vulnerabilities in cancer, autophagy, starvation signaling

Disease models: lung cancer, pancreatic cancer, hamartoma syndromes

Christina Towers, PhD

Profesor adjunto

Richard Heyman and Anne Daigle Endowed Developmental Chair

Areas of interest: cellular homeostasis in cancer via canonical and non-canonical autophagy pathways pathways; mitophagy

Disease models: cancer, neurodegeneration, infection

Ye Zheng, doctor

Profesor

Centro NOMIS de Inmunobiología y Patogénesis Microbiana

Becky and Ralph S. O'Connor Chair

Areas of interest: molecular mechanisms of regulatory and effector T cells function

Disease models: autoimmune and metabolic diseases, tumors