Deepshika Ramanan, PhD

Juniorprofessor

NOMIS Zentrum für Immunbiologie und mikrobielle Pathogenese

William Scandling Developmental Chair

Deepshika Ramanan
Salk Institut für Biologische Studien - Veröffentlichungen

Alle Veröffentlichungen


Jaquish, A., Ramanan, D. Got milk? how T cells shape lactation and beyond. (2026) Trends in Immunology. DOI: 10.1016/j.it.2026.01.007

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Frascoli, M., Nicholas, D., Weinstock, A., Hsu, C.L., Dongre, A., Osterhout, J.A., Globig, A.M., Ramanan, D., Therrien, M., McCubbrey, A. Women in STEM becoming independent: Asking for help creates opportunities for connections and kindness. (2025) Journal of Experimental Medicine. 222(10). DOI: 10.1084/jem.20251668


Jaquish, A., Phung, E., Gong, X., Baldominos, P., Galván-Peña, S., Magill, I., Bursulaya, I., Marina, E., , Bertrand, K., Chambers, C., Muñoz-Rojas, A.R., Agudo, J., Mathis, D., Benoist, C., Ramanan, D. Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis. (2025) Nature Immunology. 26(8):1411-1422. DOI: 10.1038/s41590-025-02218-3

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Wong, S.Y., Estevinho, M.M., Heaney, T., Marshall, A.A., Giselbrecht, E., Daniel, S.G., Zhou, C., Rosas-Villegas, A., Jang, K.K., Yang, H., Mabel Ko, H., Paulson, J.D., Ding, Y., Bittinger, K., Cho, J.H., Lewis, J.D., Ramanan, D., Cadwell, K. Goblet cell loss linked to NOD2 and secondary resection in Crohn's disease is induced by dysbiosis and epithelial MyD88. (2025) Cell Mol Gastroenterol Hepatol.:101533 DOI: 10.1016/j.jcmgh.2025.101533

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Jaquish, A., Phung, E., Gong, X., Baldominos-Flores, P., Galvan-Pena, S., Bursulaya, I., Magill, I., , Bertrand, K., Chambers, C., Agudo, J., Mathis, D., Benoist, C., Ramanan, D. Expansion of mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis. (2024) bioRxiv. DOI: 10.1101/2024.07.09.602739

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Ramanan, D., Chowdhary, K., Candéias, S.M., Sassone-Corsi, M., Gelineau, A., Mathis, D., Benoist, C. Homeostatic, repertoire and transcriptional relationships between colon T regulatory cell subsets. (2023) Proceedings of the National Academy of Sciences of the United States of America. 120(50):e2311566120. DOI: 10.1073/pnas.2311566120

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Ramanan, D., Pratama, A., Zhu, Y., Venezia, O., Sassone-Corsi, M., Chowdhary, K., Galván-Peña, S., Sefik, E., Brown, C., Gélineau, A., Mathis, D., Benoist, C. Regulatory T cells in the face of the intestinal microbiota. (2023) Nature Reviews. Immunology. DOI: 10.1038/s41577-023-00890-w

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Ramanan, D., Chowdhary, K., Candéias, S.M., Sassone-Corsi, M., Mathis, D., Benoist, C. Homeostatic, repertoire and transcriptional relationships between colon T regulatory cell subsets. (2023) bioRxiv. DOI: 10.1101/2023.05.17.541199

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Wu, M., Zheng, W., Song, X., Bao, B., Wang, Y., Ramanan, D., Yang, D., Liu, R., Macbeth, J.C., Do, E.A., Andrade, W.A., Yang, T., Cho, H.S., Gazzaniga, F.S., Ilves, M., Coronado, D., Thompson, C., Hang, S., Chiu, I.M., Moffitt, J.R., Hsiao, A., Mekalanos, J.J., Benoist, C., Kasper, D.L. Microbiome induced complement synthesized in the gut protects against enteric infections. (2023) bioRxiv. DOI: 10.1101/2023.02.02.523770

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Sassone-Corsi, M., Azriel, S., Simon, A., Ramanan, D., Ortiz-Lopez, A., Chen, F., Yissachar, N., Mathis, D., Benoist, C. Sequestration of gut pathobionts in intraluminal casts, a mechanism to avoid dysregulated T cell activation by pathobionts. (2022) Proceedings of the National Academy of Sciences of the United States of America. 119(41):e2209624119. DOI: 10.1073/pnas.2209624119

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Yan, Y., Ramanan, D., Rozenberg, M., McGovern, K., Rastelli, D., Vijaykumar, B., Yaghi, O., Voisin, T., Mosaheb, M., Chiu, I., Itzkovitz, S., Rao, M., Mathis, D., Benoist, C. Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut. (2021) Immunity. 54(3):499-513.e5. DOI: 10.1016/j.immuni.2021.02.002

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Ramanan, D., Sefik, E., Galván-Peña, S., Wu, M., Yang, L., Yang, Z., Kostic, A., Golovkina, T.V., Kasper, D.L., Mathis, D., Benoist, C. An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint. (2020) Cell. 181(6):1276-1290.e13. DOI: 10.1016/j.cell.2020.04.030

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Wong, S.Y., Coffre, M., Ramanan, D., Hines, M.J., Gomez, L.E., Peters, L.A., Schadt, E.E., Koralov, S.B., Cadwell, K. B Cell Defects Observed in Knockout Mice Are a Consequence of a Mutation Frequently Found in Inbred Strains. (2018) Journal of immunology. 201(5):1442-1451. DOI: 10.4049/jimmunol.1800014

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Ramanan, D., Bowcutt, R., Lee, S.C., Tang, M.S., Kurtz, Z.D., Ding, Y., Honda, K., Gause, W.C., Blaser, M.J., Bonneau, R.A., Lim, Y.A., Loke, P., Cadwell, K. Helminth infection promotes colonization resistance via type 2 immunity. (2016) Wissenschaft. 352(6285):608-12. DOI: 10.1126/science.aaf3229

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Ramanan, D., Cadwell, K. Intrinsic Defense Mechanisms of the Intestinal Epithelium. (2016) Zelle Wirt & Mikrobe. 19(4):434-41. DOI: 10.1016/j.chom.2016.03.003

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Marchiando, A.M., Ramanan, D., Ding, Y., Gomez, L.E., Hubbard-Lucey, V.M., Maurer, K., Wang, C., Ziel, J.W., van Rooijen, N., Nuñez, G., Finlay, B.B., Mysorekar, I.U., Cadwell, K. A deficiency in the autophagy gene Atg16L1 enhances resistance to enteric bacterial infection. (2013) Zelle Wirt & Mikrobe. 14(2):216-24. DOI: 10.1016/j.chom.2013.07.013

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Zhang, Z., Wu, Y., Wang, Z., Dunning, F.M., Rehfuss, J., Ramanan, D., Chapman, E.R., Jackson, M.B. Release mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cells. (2011) Molecular Biology of the Cell. 22(13):2324-36. DOI: 10.1091/mbc.E11-02-0159

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Bildung

Postdoctoral Fellow, Harvard Medical School
PhD, Immunology and Inflammation, New York University
BS, Cell and Molecular Biology, Winona State University


Auszeichnungen & Ehrungen

  • National Institute of Allergy and Infectious Diseases (NIAID) Director's New Innovators Award, 2025
  • Rita Allen Foundation Scholar, 2025
  • V Foundation for Cancer Research, V Scholar, 2023
  • Damon Runyon Dale F. Frey Breakthrough Scientist Award
  • STAT Wunderkind Award
  • The Harold M. Weintraub Graduate Student Award