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Salk Institute for Biological Studies - Cancer - Videos

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Zeitlich begrenztes Essen verbessert die Gesundheit von Feuerwehrleuten

LA JOLLA—Firefighters are the heroes of our society, protecting us around the clock. But those 24-hour shifts are hard on the body and increase the risk of cardiometabolic diseases, such as heart disease and diabetes, as well as cancer. In collaboration with the San Diego Fire-Rescue Department, scientists from the Salk Institute and UC San Diego Health conducted a clinical trial and found that time-restricted eating improved measures of health and wellbeing in firefighters. The lifestyle intervention only required the firefighters to eat during a 10-hour window and did not involve skipping meals. Mehr lesen »


Mysteriöse Mikroproteine haben große Auswirkungen auf menschliche Krankheiten

LA JOLLA – Während sich die Werkzeuge zur Untersuchung der Biologie verbessern, beginnen Forscher, Details über Mikropeptide aufzudecken, kleine Komponenten, die für einige zelluläre Prozesse, einschließlich solcher, die mit Krebs zu tun haben, von entscheidender Bedeutung zu sein scheinen. Proteine bestehen aus Ketten von verbundenen Aminosäuren, und ein durchschnittliches menschliches Protein enthält etwa 300 Aminosäuren. Mikropeptide hingegen haben weniger als 100 Aminosäuren. Mehr lesen »


Two therapeutic targets identified for deadly lung cancer

The vast majority of deadly lung cancer cases (85 percent) are termed non-small-cell lung carcinomas (NSCLCs), which often contain a mutated gene called LKB1. Salk Institute researchers have now discovered precisely why inactive LKB1 results in cancer development. The surprising results, published in the online version of Cancer Discovery on July 26, 2019, highlight how LBK1 communicates with two enzymes that suppress inflammation in addition to cell growth, to block tumor growth. The findings could lead to new therapies for NSCLC. Mehr lesen »


Tackling Pancreatic Cancer

From the beginning of the Salk Institute, with the open architecture, the emphasis on people working with and collaborating with one another has been a secret to many of the big discoveries that have been made here. With the Concurring Cancer Initiative at Salk, we have five groups each of whom represents a different discipline all of whom have a common goal and each of us are highly motivated to work with one another to cure this very devastating disease.


Zucker, die Proteine umhüllen, sind ein mögliches Angriffsziel für Medikamente bei Bauchspeicheldrüsenentzündungen

LA JOLLA – Pankreatitis ist eine Entzündung der Bauchspeicheldrüse, die in den Vereinigten Staaten jährlich zu 275.000 Krankenhausaufenthalten führt. Patienten, die darunter leiden hereditäre Pankreatitis haben ein 40- bis 50-prozentiges lebenslanges Risiko, an Bauchspeicheldrüsenkrebs zu erkranken. Mehr lesen »