Agnieszka Kendrick, PhD

Profesor adjunto

Laboratorio de Biología Molecular y Celular

Aga Kendrick
Instituto Salk de Estudios Biológicos - Publicaciones

Todas las publicaciones


de la Gándara, , Kendrick, A.A. Capturing enzymes in motion. (2025) Elife. 14. DOI: 10.7554/eLife.108727

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Nguyen, K.H.V., Karasmanis, E.P., Kendrick, A.A., Reck-Peterson, S.L., Leschziner, A.E. Cryo-EM captures early intermediate steps in dynein activation by LIS1. (2025) Nature Communications. 16(1):7054. DOI: 10.1038/s41467-025-62185-z

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Kendrick, A.A., Nguyen, K.H.V., Ma, W., Karasmanis, E.P., Amaro, R.E., Reck-Peterson, S.L., Leschziner, A.E. Multiple steps of dynein activation by Lis1 visualized by cryo-EM. (2025) Nature Structural & Molecular Biology. DOI: 10.1038/s41594-025-01558-w

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Kendrick, A.A., Nguyen, K.H.V., Ma, W., Karasmanis, E.P., Amaro, R.E., Reck-Peterson, S.L., Leschziner, A.E. Cryo-EM visualizes multiple steps of dynein's activation pathway. (2024) bioRxiv. DOI: 10.1101/2024.09.28.615567

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Karasmanis, E.P., Reimer, J.M., Kendrick, A.A., Nguyen , K.H.V., Rodriguez, J.A., Truong, J.B., Lahiri, I., Reck-Peterson , S.L., Leschziner, A.E. Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge (2023) Nature Structural & Molecular Biology. 30:1357-1364. DOI: 10.1038/s41594-023-01069-6

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Kendrick, A.A., Christensen, J.R. Bidirectional lysosome transport: a balancing act between ARL8 effectors. (2022) Nature Communications. 13(1):5261. DOI: 10.1038/s41467-022-32965-y

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Christensen, J.R., Kendrick, A.A., Truong, J.B., Aguilar-Maldonado, A., Adani, V., Dzieciatkowska, M., Reck-Peterson, S.L. Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes. (2021) Elife. 10. DOI: 10.7554/eLife.74538

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Humphries, B.A., Hwang, P.Y., Kendrick, A.A., Kulkarni, R.P., Pozzar, R.A., San Martin, R. Overstretched and overlooked: solving challenges faced by early-career investigators after the pandemic. (2021) Trends in Cancer. 7(10):879-882. DOI: 10.1016/j.trecan.2021.07.005

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Kendrick, A.A., Dickey, A.M., Redwine, W.B., Tran, P.T., Vaites, L.P., Dzieciatkowska, M., Harper, J.W., Reck-Peterson, S.L. Hook3 is a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and KIF1C. (2019) Revista de Biología Celular. 218(9):2982-3001. DOI: 10.1083/jcb.201812170

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Chi, Y.C., Rahkola, J.T., Kendrick, A.A., Holliday, M.J., Paukovich, N., Roberts, T.S., Janoff, E.N., Eisenmesser, E.Z. Streptococcus pneumoniae IgA1 protease: A metalloprotease that can catalyze in a split manner in vitro. (2017) Protein Science. 26(3):600-610. DOI: 10.1002/pro.3110

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Kendrick, A.A., Schafer, J., Dzieciatkowska, M., Nemkov, T., D'Alessandro, A., Neelakantan, D., Ford, H.L., Pearson, C.G., Weekes, C.D., Hansen, K.C., Eisenmesser, E.Z. CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming. (2017) Oncotarget. 8(4):6742-6762. DOI: 10.18632/oncotarget.14272

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Saeedi, B.J., Kao, D.J., Kitzenberg, D.A., Dobrinskikh, E., Schwisow, K.D., Masterson, J.C., Kendrick, A.A., Kelly, C.J., Bayless, A.J., Kominsky, D.J., Campbell, E.L., Kuhn, K.A., Furuta, G.T., Colgan, S.P., Glover, L.E. HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity. (2015) Biología molecular de la célula. 26(12):2252-62. DOI: 10.1091/mbc.E14-07-1194

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Kendrick, A.A., Holliday, M.J., Isern, N.G., Zhang, F., Camilloni, C., Huynh, C., Vendruscolo, M., Armstrong, G., Eisenmesser, E.Z. The dynamics of interleukin-8 and its interaction with human CXC receptor I peptide. (2014) Protein Science. 23(4):464-80. DOI: 10.1002/pro.2430

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Glover, L.E., Bowers, B.E., Saeedi, B., Ehrentraut, S.F., Campbell, E.L., Bayless, A.J., Dobrinskikh, E., Kendrick, A.A., Kelly, C.J., Burgess, A., Miller, L., Kominsky, D.J., Jedlicka, P., Colgan, S.P. Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis. (2013) Actas de la Academia Nacional de Ciencias de los Estados Unidos de América. 110(49):19820-5. DOI: 10.1073/pnas.1302840110

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Redzic, J.S., Kendrick, A.A., Bahmed, K., Dahl, K.D., Pearson, C.G., Robinson, W.A., Robinson, S.E., Graner, M.W., Eisenmesser, E.Z. Extracellular vesicles secreted from cancer cell lines stimulate secretion of MMP-9, IL-6, TGF-β1 and EMMPRIN. (2013) PLOS One. 8(8):e71225. DOI: 10.1371/journal.pone.0071225

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Kendrick, A.A., Choudhury, M., Rahman, S.M., McCurdy, C.E., Friederich, M., Van Hove, J.L., Watson, P.A., Birdsey, N., Bao, J., Gius, D., Sack, M.N., Jing, E., Kahn, C.R., Friedman, J.E., Jonscher, K.R. Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation. (2011) Biochemical Journal. 433(3):505-14. DOI: 10.1042/BJ20100791

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Educación

BS, Chemistry, University of Wroclaw
MS, Chemistry, University of Colorado, Denver
PhD, Structural Biology and Biochemistry, University of Colorado, Denver
Postdoctoral Fellow, Cellular and Molecular Medicine, University of California, San Diego


Premios y distinciones

  • Leading Edge Symposium Fellow, 2020
  • American Cancer Society Postdoctoral Fellowship, 2018
  • National Institutes of Health F32 Ruth L. Kirschstein Postdoctoral Fellowship, 2018
  • University of Colorado Graduate School Student Research Excellence Award, 2015
  • National Institutes of Health F31 Ruth L. Kirschstein Predoctoral Fellowship, 2013