Salk Institute honored with historic gift from family of the late Francis Crick

April 12, 2013

Salk Institute honored with historic gift from family of the late Francis Crick

Institute will receive half of the proceeds from record-setting auction of Crick's letter describing DNA structure

April 12, 2013

LA JOLLA, CA—On the eve of the anniversary of the first polio vaccine, the Salk Institute was honored with a generous gift from Michael Crick, the son of the late Nobel laureate and Salk faculty member, Francis Crick.

Michael Crick will donate to the institute half of the proceeds from the sale of a 1953 letter in which Francis Crick describes to his young son his recent discovery of the double-helical structure of DNA.

“Francis Crick was for many years a deeply beloved member of the Salk faculty, who pushed himself and his colleagues to ask profound scientific questions,” said Salk Institute President William R. Brody. “The Salk Institute is enormously grateful for having had the privilege to know and work with Francis, and that Michael has chosen to honor his father’s memory in this way.”

On April 25, 1953, Crick and James Watson published a historic letter in Naturaleza that described the DNA double helix, which concluded with the famous understatement that the structure “suggests a possible copying mechanism for genetic material.” Crick, Watson and Maurice Wilkins would later share the 1962 Nobel Prize in Physiology or Medicine for the discovery.

But before Crick told the world about DNA, he wrote a letter to his 12-year-old son Michael, then at boarding school. The letter was signed with paternal affection, “Lots of love Daddy,” but the contents are considered the first complete written description of the structure and mechanism of DNA, including a hand-drawn picture by Crick. Of the picture, he commented to his son, “the model looks much nicer than this.”

The model, in fact, became the basis for the entire field of modern molecular biology, enabling breakthrough insights into cancer and other diseases, a legacy carried on at the Salk Institute today.

The letter sold April 10 at Christie’s auction house to an anonymous bidder for a record price of close to $6 million. The previous record holder was an Abraham Lincoln letter that sold for $3.4 million in 2008.

After Crick reached mandatory retirement age at the Medical Research Council in Cambridge, England, he joined the Salk Institute in 1976. “The Salk allowed Francis to continue doing research for another 27 years,” Michael Crick told the New York Times.

At the Salk, Crick’s interests turned to neuroscience, where he focused on visual perception and championed research to discover the neural underpinnings of consciousness.

“His preferred way to attack a problem was to read the literature, which he knew better than most experts, and to discuss the details directly with the authors,” says his long-time colleague Terry Sejnowski, who holds the Francis Crick Chair at the Salk Institute. “On the 60th anniversary of the discovery that changed all of our lives, his curiosity and tenacity continue to inspire us all.”

Acerca del Instituto Salk de Estudios Biológicos:

El Instituto Salk de Estudios Biológicos es una de las instituciones de investigación básica más destacadas del mundo, donde un cuerpo docente de prestigio internacional investiga cuestiones fundamentales de las ciencias de la vida en un entorno único, colaborativo y creativo. Centrados tanto en el descubrimiento como en la formación de las futuras generaciones de investigadores, los científicos del Salk realizan contribuciones revolucionarias a nuestra comprensión del cáncer, el envejecimiento, el Alzheimer, la diabetes y las enfermedades infecciosas mediante el estudio de la neurociencia, la genética, la biología celular y vegetal, y otras disciplinas relacionadas.

Los logros del cuerpo docente han sido reconocidos con numerosos galardones, entre los que se incluyen premios Nobel y la pertenencia a la Academia Nacional de Ciencias. Fundado en 1960 por el Dr. Jonas Salk, pionero en la vacuna contra la poliomielitis, el Instituto es una organización independiente sin fines de lucro y un hito arquitectónico.