LA JOLLA, CA—A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer’s disease in aged mice following short-term treatment. The findings, published May 14 in the journal Alzheimer’s Research and Therapy, may pave the way to a new treatment for Enfermedad de Alzheimer en humanos.
LA JOLLA, CA—Scientists have long known that control mechanisms known collectively as “epigenetics” play a critical role in human development, but they did not know precisely how alterations in this extra layer of biochemical instructions in DNA contribute to development.
LA JOLLA, CA—Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing’s disease, a development that may give clinicians a therapeutic target to treat this potentially life-threatening disorder.
LA JOLLA, CA—In the spring following a forest fire, trees that survived the blaze explode in new growth and plants sprout in abundance from the scorched earth. For centuries, it was a mystery how seeds, some long dormant in the soil, knew to push through the ashes to regenerate the burned forest.
LA JOLLA, CA—Liver fibrosis results from an excessive accumulation of tough, fibrous scar tissue and occurs in most types of chronic liver diseases. In industrialized countries, the main causes of liver injury leading to fibrosis include chronic hepatitis virus infection, excess alcohol consumption and, increasingly, nonalcoholic steatohepatitis (NASH).
LA JOLLA, CA—Investigador del Salk Terrence J. Sejnowski,
professor and head of the Computational Neurobiology Laboratory, has been elected a Fellow of the Academia Estadounidense de Artes y Ciencias, a distinction awarded annually to global leaders in business, government, public affairs, the arts and popular culture as well as biomedical research.
LA JOLLA, CA—On April 12, the Salk Institute unanimously approved the election of Sanjay Jha, former CEO of Motorola Mobility, to its Board of Trustees.
LA JOLLA, CA—The Salk Institute is pleased to announce the promotions of faculty members, John Reynolds to the rank of full professor and Clodagh O’Shea and Tatyana Sharpee to associate professors based on recommendations by the Salk faculty and nonresident fellows, and approved by President William R. Brody and the Institute’s Board of Trustees.
LA JOLLA, CA—On the eve of the anniversary of the first polio vaccine, the Salk Institute was honored with a generous gift from Michael Crick, the son of the late Nobel laureate and Salk faculty member, Francis Crick.
LA JOLLA, CA—The irony of getting away to a remote place is you usually have to fight traffic to get there. After hours of dodging dangerous drivers, you finally arrive at that quiet mountain retreat, stare at the gentle waters of a pristine lake, and congratulate your tired self on having “turned off your brain.”
LA JOLLA, CA—The Salk Institute is pleased to announce Step into Discovery, a day featuring the inaugural 5K Walk for Salk and Explore Salk, a free community open house offering behind-the-scenes tours of the world-renowned Institute.
LA JOLLA, CA—Salk neuroscientist Terrence J. Sejnowski joined President Barack Obama in Washington, D.C., on April 2, 2013, at the launch of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative—a major Administration neuroscience effort that advances and builds upon collaborative scientific work by leading brain researchers such as Salk’s own Sejnowski.
LA JOLLA, CA—On the eve of the 60th anniversary of the discovery of DNA, James Watson, a legendary scientist who helped changed the history of molecular biology, spoke at the Salk Institute about his recent work in cancer research.
LA JOLLA, CA—The American Association for Cancer Research (AACR), the world’s oldest and largest professional organization dedicated to accelerating scientific progress to prevent and cure cancer, has selected four Salk scientists and two of the Institute’s nonresident fellows to be inducted in its first class of the fellows of the AACR Academy.
LA JOLLA, CA—¿Alguna vez te encuentras comiéndote la cabeza un lunes por la mañana para recordar dónde dejaste las llaves del coche?
LA JOLLA, California—Un equipo de científicos, entre los que se encuentran investigadores del Instituto Salk de Estudios Biológicos, ha descubierto que un medicamento utilizado para tratar las aftas bucales parece revertir la obesidad en ratones. Los hallazgos, publicados el 10 de febrero en Nature Medicine, podría dar lugar a nuevos medicamentos para bajar de peso que podrían tener un impacto en las crecientes tasas de obesidad y diabetes en los Estados Unidos.
El medicamento, el amlexanox, lleva más de 15 años en el mercado. En Japón se utilizan diferentes formulaciones del medicamento para tratar el asma, mientras que en Estados Unidos se emplean para tratar las aftas bucales. Se prevé que los ensayos clínicos en humanos para la pérdida de peso comiencen a finales de este año.
LA JOLLA, CA—Scientists at the Salk Institute for Biological Studies have identified patterns of epigenomic diversity that not only allow plants to adapt to various environments, but could also benefit crop production and the study of human diseases.
Ian Trowbridge, an esteemed researcher who had been a member of the Salk faculty for almost three decades, passed away on Wednesday, February 6.
LA JOLLA, CA—You might think you have nothing in common with mustard except hotdogs. Yet based on research in a plant from the mustard family, Salk scientists have discovered a possible explanation for how organisms, including humans, directly regulate chemical reactions that quickly adjust the growth of organs. These findings overturn conventional views of how different body parts coordinate their growth, shedding light on the development of more productive plants and new therapies for metabolic diseases.
LA JOLLA, CA—In this week’s Naturaleza Métodos, Salk researchers share a how-to secret for biologists: code for Amazon Cloud that significantly reduces the time necessary to process data-intensive microscopic images.
