STAR PERFORMERS ON STAGE OR SCREEN MAY RECEIVE THE
applause, but no complex production comes to fruition without an
extensive team of skilled individuals working behind the spotlight.
So it is with science.
While notable discoveries in Salk laboratories make headlines,
enabling these achievements is the provenance of our scientific
core facilities. We like to call them “idea factories” because they
provide the cutting-edge technology and expertise that allow our
scientists to perform the novel experiments they envision. In this
issue they’re getting a well-deserved turn in the spotlight.
Also receiving recognition are three Salk faculty members who have
been awarded chairs.
is the inaugural holder of the
Fiona and Sanjay Jha Chair in Neuroscience.
another new chair, the Salk Founders’ Chair. And
has been named holder of the Dr. Frederik Paulsen Chair.
Discoveries at the Institute continue to pour forth at an impressive
and his team have developed a technique that lets
researchers watch—for the first time—motor neuron activity in the
’s group has linked a particular
receptor in the mouse brain to aberrant behavior. Research with
cellular proteins in
’s lab is revealing how age affects
organs in strikingly different ways. And
and his team
are uncovering ways to harness the immune system.
Other notable findings at the Institute are advancing our understand-
ing of cancer.
’s lab identified a key molecular mechanism
underlying deadly behavior in some breast cancers. A group led by
showed how disabling a chromosome’s telomeres could
’s team, in collaboration with scientists
at Sanford Burnham Prebys Medical Discovery Institute, developed a
drug that blocks cancerous cells from obtaining nutrients. And novel
’s lab is paving the way for cancer-selective
Critical to all these accomplishments are Salk’s loyal donors and
we take pleasure in honoring them in this issue in our annual Donor
Honor Roll. Much like the go-to experts in our core facilities, donors
are part of the team behind the scenes who make revolutionary
This is my last message as President of the Salk Institute, as I will be
stepping down at the end of December. It has been my privilege to
work among such prodigious talent. Salk is in good shape and in good
hands, and the future looks bright indeed. I wish you all well.
William R. Brody, MD, PhD
President, Salk Institute
Irwin M. Jacobs Presidential Chairwww.salk.ed
Inside Salk 12 | 15
ON THE COVER
Salk’s 13 shared scientific facilities, or cores, enable discoveries and innovative breakthroughs to Salk labs.
The cores offer state-of-the-art technology and expertise on everything from stem cells to analyzing genomic data.
Where cures begin.
P H I L O S O P H Y
In this issue:2015DonorHonorRoll