Inside Salk - July 2012 - page 5

Inside Salk 07|12
Lead Story
Dulbecco, a Founding Fellowof Salk,
was awarded theNobel Prize in 1975, along
withHoward Temin andDavidBaltimore, who
workedwithDulbecco at different times, for
their discoveries illuminating how tumor viruses
interact with the geneticmaterial within a cell.
Dulbecco demonstrated how a virus could insert
its own genes into the DNA of the cell it infects,
sparking cancer growth. In essence, his work
helped uncover some of themolecular pathways
that define cancer growth however it occurs,
providing the conceptual breakthrough that has
guided the field ever since.
Dulbecco’s story is one of a remarkable
scientist, and it is also a story of an enduring
scientific legacy that carries on to this day.
Over the course of his career, Dulbecco trained
and collaborated with some of the leading biol-
ogists in the world, and his life andwork charted
a course for many young cancer researchers.
“He had a broader vision of science than
most and a keen instinct for important
problems to solve,” says
Tony Hunter
, holder
of the Renato Dulbecco Chair and a professor
in theMolecular and Cell Biology Laboratory
and director of the Salk Institute Cancer
Center. “His work drew outstanding young
investigators to Salk and influenced a whole
generation of biologists.”
Jonas Salk andRenatoDulbecco in the courtyard, 1967
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