{"id":892,"date":"2015-09-30T13:56:20","date_gmt":"2015-09-30T20:56:20","guid":{"rendered":"https:\/\/vermont.salk.edu\/?page_id=892"},"modified":"2024-01-30T14:18:18","modified_gmt":"2024-01-30T22:18:18","slug":"glenn-center-for-research-on-aging","status":"publish","type":"page","link":"https:\/\/www.salk.edu\/zh\/science\/research-centers\/glenn-center-for-research-on-aging\/","title":{"rendered":"Glenn Center Overview"},"content":{"rendered":"<div style=\"width:280px; float: right; font-size:16px; background-color: #DEECFF; padding:10px 30px; border: 1px solid;\"><a href=\"https:\/\/www.salk.edu\/zh\/news-release\/in-memoriam-paul-f-glenn\/\">In Memoriam: Paul F. Glenn Salk Institute remembers visionary aging-research benefactor<\/a><\/div>\n<p>The Glenn Center for Research on Aging was established in January 2009 with a $5 million award from the <a href=\"http:\/\/glennfoundation.org\" target=\"_blank\" rel=\"noopener noreferrer\">Glenn Foundation for Medical Research<\/a>. The Glenn Foundation continued their generous support with  $3 million awards in 2014 and 2017. Led by Salk professors <a href=\"https:\/\/www.salk.edu\/zh\/scientist\/jan-karlseder\/\">Jan Karlseder<\/a> \u548c <a href=\"https:\/\/www.salk.edu\/zh\/scientist\/gerald-shadel\/\">Gerald Shadel<\/a>, the Center draws from 13 of Salk&#8217;s leading laboratories specializing in genetic analysis, stem cell biology and metabolism research to address the overarching goal of defining a healthy lifespan, or healthspan, and to answer one of the most elusive questions in biology: Is there a defined biological process of aging that is universal to all organisms?<\/p>\n<p>\nThe Glenn Center supports postdoctoral associates and graduate students (Glenn Fellows) working in the laboratories of the Glenn Investigators, focusing on innovative questions that address the biology of aging. Furthermore, the Glenn Center funds state-of-the-art equipment, core support and scientific exchange for the participating laboratories. <\/p>\n<blockquote><p>\n&#8220;The biology of aging underlies all the major human diseases. To understand the fundamental aging process and to intervene is to delay the onset of disease, to extend the healthful years of life and reduce costs to society.&#8221;<br \/>\n&#8212; Mark R. Collins, Glenn Foundation President\n<\/p><\/blockquote>\n<h2>A better world for older people is a better world for everyone<\/h2>\n<p><iframe src=\"https:\/\/www.youtube.com\/embed\/X-qlo9eVd3c?rel=0\" frameborder=\"0\" allowfullscreen><\/iframe><br \/>\n<strong>Jan Karlseder<\/strong><br \/>\nDirector<br \/>\nThe Paul F. Glenn Center for Biology of Aging Research<br \/>\n(858) 453-4100 x1867<br \/>\n<a href=\"mailto:karlseder@salk.edu\">karlseder@salk.edu<\/a>\n<\/p>\n<p>\n<strong>Gerald Shadel<\/strong><br \/>\nAssociate Director<br \/>\nThe Paul F. Glenn Center for Biology of Aging Research<br \/>\n(858) 453-4100 x2244<br \/>\n<a href=\"mailto:gshadel@salk.edu\">gshadel@salk.edu<\/a><\/p>","protected":false},"excerpt":{"rendered":"<div style=\"width:280px; float: right; font-size:16px; background-color: #DEECFF; padding:10px 30px; border: 1px solid;\"><a href=\"https:\/\/www.salk.edu\/zh\/news-release\/in-memoriam-paul-f-glenn\/\">In Memoriam: Paul F. Glenn Salk Institute remembers visionary aging-research benefactor<\/a><\/div>\n<p>The Glenn Center for Research on Aging was established in January 2009 with a $5 million award from the <a href=\"http:\/\/glennfoundation.org\" target=\"_blank\" rel=\"noopener noreferrer\">Glenn Foundation for Medical Research<\/a>. The Glenn Foundation continued their generous support with  $3 million awards in 2014 and 2017. Led by Salk professors <a href=\"https:\/\/www.salk.edu\/zh\/scientist\/jan-karlseder\/\">Jan Karlseder<\/a> \u548c <a href=\"https:\/\/www.salk.edu\/zh\/scientist\/gerald-shadel\/\">Gerald Shadel<\/a>, the Center draws from 13 of Salk&#8217;s leading laboratories specializing in genetic analysis, stem cell biology and metabolism research to address the overarching goal of defining a healthy lifespan, or healthspan, and to answer one of the most elusive questions in biology: Is there a defined biological process of aging that is universal to all organisms?<\/p>","protected":false},"author":3,"featured_media":907,"parent":76,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-research-centers-overview.php","meta":{"_acf_changed":false,"footnotes":""},"folder":[535],"class_list":["post-892","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Glenn Center Overview - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/zh\/science\/research-centers\/glenn-center-for-research-on-aging\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Glenn Center Overview - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"In Memoriam: Paul F. Glenn Salk Institute remembers visionary aging-research benefactor The Glenn Center for Research on Aging was established in January 2009 with a $5 million award from the Glenn Foundation for Medical Research. The Glenn Foundation continued their generous support with $3 million awards in 2014 and 2017. 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Glenn Center for Biology of Aging Research","line_2":"Overview","secondary_navigation":"<div class=\"menu-glenn-center-for-research-on-aging-container\"><ul id=\"menu-glenn-center-for-research-on-aging\" class=\"menu\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-900\"><a href=\"https:\/\/www.salk.edu\/zh\/science\/research-centers\/glenn-center-for-research-on-aging\/\">Overview<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-5296\"><a href=\"https:\/\/www.salk.edu\/zh\/science\/research-centers\/glenn-center-for-research-on-aging\/research\/\">Research<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-898\"><a href=\"https:\/\/www.salk.edu\/zh\/science\/research-centers\/glenn-center-for-research-on-aging\/glenn-center-faculty\/\">People<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-902\"><a href=\"https:\/\/www.salk.edu\/zh\/science\/research-centers\/glenn-center-for-research-on-aging\/fellows\/\">Fellows<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-896\"><a href=\"https:\/\/www.salk.edu\/zh\/science\/research-centers\/glenn-center-for-research-on-aging\/contact\/\">Contact<\/a><\/li>\n<\/ul><\/div>","disease_research":[{"title":"Aging Research at the Salk Institute, a Multipronged Approach","description":"<p>The Salk Institute has a unique culture of interdisciplinary collaboration, fostered by interaction between research groups with multiple objectives. Unobstructed by departmental walls, investigators move beyond the focus of their laboratories to communicate across disciplines, tackle questions from multiple angles and accelerate the rate of discovery. <\/p>\n<p>The Glenn Center for Research on Aging at the Salk Institute focuses on a three- level approach: whole systems biology, organ biology and cellular aging biology. Expertise on each level is required to understand aging, age related disease and the difference between healthy and pathological aging. Researchers at the Salk Institute are uniquely suited to such an interdependent model as they have a long history and record of a small and highly collaborative approach toward projects and questions that are too complex for individuals. <\/p>\n<p>As a group, researchers have deep expertise in metabolism, organ and tissue regeneration, stem cell biology, neurobiology and neurodegenerative diseases, inflammation, telomere biology, senescence, genome stability, cancer biology, nuclear structure, genome organization and cell signaling. Free information exchange across these disciplines allows scientists to rapidly move between cells, organs and systems, enormously accelerating the rate of discovery and understanding. The Glenn Center, with its emphasis on multidisciplinary projects, is particularly situated to benefit from this culture of collaboration. <\/p>","image":false},{"title":"Healthy Aging and Age Related Disease","description":"<p>Understanding the biology of healthy aging is a major focus of the Salk Institute, and the Glenn Center for Research on Aging nucleates faculty interested in life span, health span and age-related disease. <\/p>\n<p>The onset of age-related disease is often synergistic and limits the health span. How do reseachers generate an all-encompassing hypothesis for aging? Scientists are focusing on individual aspects of aging, from inflammation to telomere function to cancer onset. It is highly likely that multiple, seemingly unrelated issues feed into common readouts and effector pathways. How do these get defined? Are aging-driven changes in chromatin structure, nuclear territories and chromosomal interactions determinant factors that influence health span, life span and the synergy of diseases? As a group, Glenn researchers are focusing on understanding nuclear structure, epigenetics and the importance of nuclear territories on aging, life span, health span and stem cell biology. <\/p>","image":false}],"gallery":false,"poster_quote":"","featured_image_link":"","salk_custom_body_class":""},"_links":{"self":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/pages\/892","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/comments?post=892"}],"version-history":[{"count":14,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/pages\/892\/revisions"}],"predecessor-version":[{"id":45662,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/pages\/892\/revisions\/45662"}],"up":[{"embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/pages\/76"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/media\/907"}],"wp:attachment":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/media?parent=892"}],"wp:term":[{"taxonomy":"folder","embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/folder?post=892"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}