{"id":54231,"date":"2025-08-05T18:59:07","date_gmt":"2025-08-06T01:59:07","guid":{"rendered":"https:\/\/www.salk.edu\/?page_id=54231"},"modified":"2025-08-13T17:08:57","modified_gmt":"2025-08-14T00:08:57","slug":"institute-faqs","status":"publish","type":"page","link":"https:\/\/www.salk.edu\/zh\/about\/institute-faqs\/","title":{"rendered":"\u5b66\u9662\u5e38\u89c1\u95ee\u9898\u89e3\u7b54"},"content":{"rendered":"<a class=\"openall btn -expand\">Expand All<\/a><a class=\"closeall btn -expand\">Collapse All<\/a>\r\n\r\n<div id=\"accordion1\" class=\"accordion\" style=\"margin-top: 20px;\">\r\n\r\n<!-- Question 1 -->\r\n<div class=\"accordion-group\">\r\n<div class=\"accordion-heading\"><a class=\"accordion-toggle collapsed\" href=\"#collapseOne\" data-toggle=\"collapse\" data-parent=\"#accordion1\" aria-expanded=\"false\">What is the Salk Institute?<\/a><\/div>\r\n\r\n<div id=\"collapseOne\" class=\"accordion-body collapse\" style=\"height: 0px;\" aria-expanded=\"false\">\r\n<div class=\"accordion-inner\">\r\n<p>The Salk Institute is an independent, nonprofit research organization founded in 1960 by Jonas Salk, developer of the first safe and effective polio vaccine. The Institute buildings are an architectural landmark, designed by renowned architect Louis Kahn, overlooking the Pacific Ocean in La Jolla, California.<\/p>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<!-- End Question 1 -->\r\n\r\n<!-- Question 2 -->\r\n<div class=\"accordion-group\">\r\n<div class=\"accordion-heading\"><a class=\"accordion-toggle collapsed\" href=\"#collapseTwo\" data-toggle=\"collapse\" data-parent=\"#accordion1\" aria-expanded=\"false\">What is Salk\u2019s mission?<\/a><\/div>\r\n\r\n<div id=\"collapseTwo\" class=\"accordion-body collapse\" style=\"height: 0px;\" aria-expanded=\"false\">\r\n<div class=\"accordion-inner\">\r\n<p>To explore the fundamental processes of life for the benefit of all and to empower the next generation of scientists.<\/p>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<!-- End Question 2 -->\r\n\r\n<!-- Question 3 -->\r\n<div class=\"accordion-group\">\r\n<div class=\"accordion-heading\"><a class=\"accordion-toggle collapsed\" href=\"#collapseThree\" data-toggle=\"collapse\" data-parent=\"#accordion1\" aria-expanded=\"false\">What do Salk scientists do?<\/a><\/div>\r\n\r\n<div id=\"collapseThree\" class=\"accordion-body collapse\" style=\"height: 0px;\" aria-expanded=\"false\">\r\n<div class=\"accordion-inner\">\r\n<p>Salk is home to one of seven US National Cancer Institute-Designated Cancer Centers dedicated to basic laboratory research. Other major areas of research at Salk are healthy aging, immunobiology, neuroscience, metabolism, plant biology, biochemistry, and computational biology.<\/p>\r\n\r\n<p>Salk scientists study the basic principles of biology across multiple research areas to address pressing global challenges, such as cancer, diabetes, Alzheimer\u2019s disease, and crop resilience.<\/p>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<!-- End Question 3 -->\r\n\r\n<!-- Question 4 -->\r\n<div class=\"accordion-group\">\r\n<div class=\"accordion-heading\"><a class=\"accordion-toggle collapsed\" href=\"#collapseFour\" data-toggle=\"collapse\" data-parent=\"#accordion1\" aria-expanded=\"false\">Why is basic, or foundational, research so important?<\/a><\/div>\r\n\r\n<div id=\"collapseFour\" class=\"accordion-body collapse\" style=\"height: 0px;\" aria-expanded=\"false\">\r\n<div class=\"accordion-inner\">\r\n<p>Basic research seeks to uncover fundamental truths about biology, health, and the environment, often without immediate commercial applications. This kind of research lays the groundwork for nearly every major scientific breakthrough, from vaccines and cancer therapies to advances in neuroscience and agricultural science. By understanding how life works at its most basic levels, scientists can develop transformative solutions for the future. Without foundational research, the translational scientists wouldn\u2019t have anything to \u201ctranslate\u201d to the clinic.<\/p>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<!-- End Question 4 -->\r\n\r\n<!-- Question 5 -->\r\n<div class=\"accordion-group\">\r\n<div class=\"accordion-heading\"><a class=\"accordion-toggle collapsed\" href=\"#collapseFive\" data-toggle=\"collapse\" data-parent=\"#accordion1\" aria-expanded=\"false\">How is foundational research funded?<\/a><\/div>\r\n\r\n<div id=\"collapseFive\" class=\"accordion-body collapse\" style=\"height: 0px;\" aria-expanded=\"false\">\r\n<div class=\"accordion-inner\">\r\n<p>Foundational research is primarily funded through a combination of competitive government grants, private foundations, and philanthropy. While public funding supports many projects, it often prioritizes short-term outcomes. Philanthropic support is essential to fuel bold, high-risk ideas and long-term discoveries that traditional funding sources may overlook.<\/p>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<!-- End Question 5 -->\r\n\r\n<!-- Question 6 -->\r\n<div class=\"accordion-group\">\r\n<div class=\"accordion-heading\"><a class=\"accordion-toggle collapsed\" href=\"#collapseSix\" data-toggle=\"collapse\" data-parent=\"#accordion1\" aria-expanded=\"false\">What discoveries is Salk best known for?<\/a><\/div>\r\n\r\n<div id=\"collapseSix\" class=\"accordion-body collapse\" style=\"height: 0px;\" aria-expanded=\"false\">\r\n<div class=\"accordion-inner\">\r\n<p>Salk discoveries have led to new therapeutic approaches that overturned previous thinking, including, for example:<\/p>\r\n\r\n<ul>\r\n<li>Discovery of a cellular switch called <strong>tyrosine phosphorylation<\/strong>, which has led to more than 60 cancer drugs that work by inhibiting that switch. The first of these drugs is Gleevec (imatinib), which is used to treat leukemias and other blood cancers.<\/li>\r\n<li>Discovery of <strong>peptide hormone production in the brain<\/strong> that controls the release of hormones from the pituitary and other organs. One such peptide, somatostatin, is used to treat neuroendocrine tumors and other endocrine diseases.<\/li>\r\n<li>Discovery of <strong>neurotransmitter receptors for acetylcholine and glutamate<\/strong>, which are important drug targets for the treatment of myasthenia gravis, Alzheimer\u2019s disease, and neuropsychiatric disorders.<\/li>\r\n<li>Discovery of <strong>nuclear hormone receptors<\/strong>, which are now primary targets in the treatment of breast cancer, prostate cancer, pancreatic cancer, leukemia, osteoporosis, and asthma.<\/li>\r\n<li>Pioneering work on <strong>neural networks<\/strong> that formed the foundation for remarkable advances in artificial intelligence and machine learning.<\/li>\r\n<li>Discovery that the <strong>adult brain continues to produce new neurons<\/strong> throughout life in a process called neurogenesis, contrary to previously accepted dogma, opening new avenues for research on Alzheimer\u2019s and other neurodegenerative diseases.<\/li>\r\n<li>Discovery of the <strong>health benefits of time-restricted eating<\/strong>, including weight loss, blood sugar regulation, and improved metabolic function.<\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<!-- End Question 6 -->\r\n\r\n<!-- Question 7 -->\r\n<div class=\"accordion-group\">\r\n<div class=\"accordion-heading\"><a class=\"accordion-toggle collapsed\" href=\"#collapseSeven\" data-toggle=\"collapse\" data-parent=\"#accordion1\" aria-expanded=\"false\">Where is Salk headed?<\/a><\/div>\r\n\r\n<div id=\"collapseSeven\" class=\"accordion-body collapse\" style=\"height: 0px;\" aria-expanded=\"false\">\r\n<div class=\"accordion-inner\">\r\n<p>The Salk Institute will continue to be a global leader in biological research at the cutting edge of scientific innovation. It will continue to attract the world\u2019s most talented scientists to an environment that is entirely focused on making impactful scientific discoveries. New research directions for Salk science include:<\/p>\r\n\r\n<ul>\r\n<li>Substantial investment in <strong>biocomputation technologies<\/strong>, including artificial intelligence, to support all areas of Salk science.<\/li>\r\n<li>A new <strong>Neuroimmunology Initiative<\/strong> that combines Salk\u2019s world-leading neuroscientists and immunobiologists to address neuroinflammatory diseases, especially Alzheimer\u2019s.<\/li>\r\n<li>Multi-investigator efforts by Salk Cancer Center researchers to address the <strong>most deadly cancers<\/strong>, studying cancer cells in the context of their local environment, as populated by immune cells and other cell types.<\/li>\r\n<li>Advancing plant science, with a focus on understanding the mechanisms of root-enhancing traits and combining those traits to provide <strong>Salk Ideal Plants<\/strong> that can achieve large-scale carbon dioxide sequestration, improve crop resilience, and enrich soils.<\/li>\r\n<li>Combining molecular, cellular, and physiologic approaches to the study of <strong>metabolism and aging<\/strong>, with an emphasis on how each individual\u2019s aging process is driven by their unique biology, background, environment, and lifestyle. <\/li>\r\n<li>Concerted efforts in <strong>behavioral neuroscience<\/strong>, linking the neural circuits that underlie behavior to the physical and social environment of the individual. The development of novel imaging techniques.<\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<!-- End Question 7 -->\r\n\r\n<!-- Question 8 -->\r\n<div class=\"accordion-group\">\r\n<div class=\"accordion-heading\"><a class=\"accordion-toggle collapsed\" href=\"#collapseEight\" data-toggle=\"collapse\" data-parent=\"#accordion1\" aria-expanded=\"false\">How can I help? <\/a><\/div>\r\n\r\n<div id=\"collapseEight\" class=\"accordion-body collapse\" style=\"height: 0px;\" aria-expanded=\"false\">\r\n<div class=\"accordion-inner\">\r\n<p>With philanthropic investment, Salk will recruit top faculty members, research staff, and scientific trainees to conduct research in pursuit of breakthrough discoveries. Salk also helps build a diverse STEM career pipeline through research and training programs for high school, college, and graduate students and postdoctoral trainees. All gifts to Salk are used to support its research enterprise.<\/p>\r\n\r\n<a href=\"https:\/\/salkinstitute.donorsupport.co\/-\/XHQRPRJT\" class=\"btn -expand\">Donate Today<\/a>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<!-- End Question 8 -->\r\n\r\n<\/div>","protected":false},"excerpt":{"rendered":"<a class=\"openall btn -expand\">Expand All<\/a><a class=\"closeall btn -expand\">Collapse All<\/a>\r\n\r\n<div id=\"accordion1\" class=\"accordion\" style=\"margin-top: 20px;\">\r\n\r\n<!-- Question 1 -->\r\n<div class=\"accordion-group\">\r\n<div class=\"accordion-heading\"><a class=\"accordion-toggle collapsed\" href=\"#collapseOne\" data-toggle=\"collapse\" data-parent=\"#accordion1\" aria-expanded=\"false\">What is the Salk Institute?<\/a><\/div>\r\n\r\n<div id=\"collapseOne\" class=\"accordion-body collapse\" style=\"height: 0px;\" aria-expanded=\"false\">\r\n<div class=\"accordion-inner\">\r\n<p>The Salk Institute is an independent, nonprofit research organization founded in 1960 by Jonas Salk, developer of the first safe and effective polio vaccine. The Institute buildings are an architectural landmark, designed by renowned architect Louis Kahn, overlooking the Pacific Ocean in La Jolla, California.<\/p>","protected":false},"author":91,"featured_media":0,"parent":5,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"folder":[509],"class_list":["post-54231","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Institute FAQs - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/zh\/about\/institute-faqs\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Institute FAQs - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"Expand AllCollapse All      What is the Salk Institute?    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Science","publisher":{"@id":"https:\/\/www.salk.edu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.salk.edu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"zh-CN"},{"@type":"Organization","@id":"https:\/\/www.salk.edu\/#organization","name":"\u7d22\u5c14\u514b\u751f\u7269\u7814\u7a76\u6240","url":"https:\/\/www.salk.edu\/","logo":{"@type":"ImageObject","inLanguage":"zh-CN","@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/","url":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","contentUrl":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","width":696,"height":696,"caption":"Salk Institute for Biological Studies"},"image":{"@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/"}}]}},"ACF":{"hero":false,"line_1":"About","line_2":"Institute FAQs","poster_quote":"","gallery":false,"salk_custom_body_class":"","secondary_navigation":"<div class=\"menu-about-container\"><ul id=\"menu-about\" class=\"menu\"><li class=\"menu-item menu-item-type-custom menu-item-object-custom menu-item-40302\"><a href=\"\/about\/\">Overview<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-16181\"><a href=\"https:\/\/www.salk.edu\/zh\/people\/management-team\/\">Leadership<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6803\"><a href=\"https:\/\/www.salk.edu\/zh\/about\/awards-and-accolades\/\">Awards<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-31274\"><a href=\"https:\/\/www.salk.edu\/zh\/about\/our-community\/\">Our Community<\/a><\/li>\n<li class=\"menu-item menu-item-type-custom menu-item-object-custom menu-item-37215\"><a href=\"https:\/\/www.salk.edu\/about\/visiting-salk\/\">Visiting<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6169\"><a href=\"https:\/\/www.salk.edu\/zh\/about\/history-of-salk\/\">History<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6172\"><a href=\"https:\/\/www.salk.edu\/zh\/about\/education-outreach\/\">Education Outreach<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-54295\"><a href=\"https:\/\/www.salk.edu\/zh\/about\/institute-faqs\/\">Institute FAQs<\/a><\/li>\n<li class=\"menu-item menu-item-type-custom menu-item-object-custom menu-item-6193\"><a href=\"\/contact\">Contact<\/a><\/li>\n<\/ul><\/div>"},"_links":{"self":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/pages\/54231","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/users\/91"}],"replies":[{"embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/comments?post=54231"}],"version-history":[{"count":9,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/pages\/54231\/revisions"}],"predecessor-version":[{"id":54292,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/pages\/54231\/revisions\/54292"}],"up":[{"embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/pages\/5"}],"wp:attachment":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/media?parent=54231"}],"wp:term":[{"taxonomy":"folder","embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/folder?post=54231"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}