{"id":35950,"date":"2022-09-22T00:00:02","date_gmt":"2022-09-22T07:00:02","guid":{"rendered":"https:\/\/vermont.salk.edu\/?post_type=disclosure&#038;p=35950"},"modified":"2022-09-22T08:00:37","modified_gmt":"2022-09-22T15:00:37","slug":"salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/zh\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/","title":{"rendered":"\u7d22\u5c14\u514b\u7814\u7a76\u6240\u5c06\u7275\u5934$\u8017\u8d441.26\u4ebf\u7f8e\u5143\u7684\u8ba1\u5212\uff0c\u7ed8\u5236\u8870\u8001\u7684\u4eba\u7c7b\u5927\u8111\u56fe\u8c31"},"content":{"rendered":"<p>\u62c9\u8377\u4e9a\u2014\u2014\u5728\u56fd\u5bb6\u536b\u751f\u7814\u7a76\u9662 (NIH) \u63d0\u4f9b\u7684\u4e3a\u671f\u4e94\u5e74\u3001$1.26 \u4ebf\u7f8e\u5143\u7684\u8d44\u52a9\u4e0b\uff0c\u7531\u8428\u514b\u7814\u7a76\u6240\u79d1\u5b66\u5bb6\u9886\u5bfc\u7684\u4e00\u4e2a\u56e2\u961f\u542f\u52a8\u4e86\u4e00\u4e2a\u65b0\u7684\u591a\u7ec4\u5b66\u4eba\u7c7b\u5927\u8111\u7ec6\u80de\u56fe\u8c31\u4e2d\u5fc3\u3002\u4f5c\u4e3a NIH \u7684\u4e00\u90e8\u5206 <a href=\"https:\/\/braininitiative.nih.gov\/\" target=\"_blank\" rel=\"noopener\"><em>\u8111\u79d1\u5b66\u901a\u8fc7\u5148\u8fdb\u7684\u521b\u65b0\u795e\u7ecf\u6280\u672f\u7814\u7a76<\/em>\u00ae (\u8111\u79d1\u5b66) \u8ba1\u5212<\/a>, \u8be5\u9879\u76ee\u65e8\u5728\u4ee5\u524d\u6240\u672a\u6709\u7684\u5206\u5b50\u7ec6\u8282\u6765\u63cf\u8ff0\u7ec4\u6210\u4eba\u8111\u7684\u7ec6\u80de\uff0c\u5c06\u8111\u7ec6\u80de\u5212\u5206\u4e3a\u66f4\u7cbe\u786e\u7684\u4e9a\u578b\uff0c\u5e76\u786e\u5b9a\u6bcf\u79cd\u7ec6\u80de\u5728\u4eba\u8111\u4e2d\u7684\u4f4d\u7f6e\u3002\u6b64\u5916\uff0c\u8be5\u56e2\u961f\u8fd8\u5c06\u8ffd\u8e2a\u8fd9\u4e9b\u7279\u5f81\u4ece\u751f\u547d\u65e9\u671f\u5230\u665a\u671f\u7684\u53d8\u5316\u3002.<\/p>\n<p>\u8be5\u9879\u76ee\u7684\u76ee\u6807\u662f\u66f4\u597d\u5730\u4e86\u89e3\u795e\u7ecf\u5178\u578b\u4eba\u8111\u7684\u5de5\u4f5c\u65b9\u5f0f\u548c\u8870\u8001\u8fc7\u7a0b\u3002\u8be5\u9879\u76ee\u8fd8\u5c06\u5efa\u7acb\u4e00\u4e2a\u57fa\u51c6\uff0c\u79d1\u5b66\u5bb6\u4eec\u53ef\u4ee5\u5bf9\u7167\u8be5\u57fa\u51c6\u6765\u6bd4\u8f83\u60a3\u6709\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3001\u81ea\u95ed\u75c7\u3001\u6291\u90c1\u75c7\u548c\u521b\u4f24\u6027\u8111\u635f\u4f24\u7b49\u795e\u7ecf\u7cfb\u7edf\u6216\u7cbe\u795e\u75be\u75c5\u7684\u5927\u8111\u3002.<\/p>\n<figure id=\"attachment_35954\"  class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"200\" class=\"img-responsive wp-image-35954 size-medium\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-300x200.jpg\" alt=\"From left: Margarita Behrens and Joseph Ecker\" srcset=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-300x200.jpg 300w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-1024x683.jpg 1024w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-768x512.jpg 768w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-147x98.jpg 147w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-458x305.jpg 458w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-585x390.jpg 585w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-553x369.jpg 553w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-750x500.jpg 750w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-767x511.jpg 767w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-945x630.jpg 945w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-1250x833.jpg 1250w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-400x267.jpg 400w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500.jpg 1500w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption class=\"wp-caption-text\">\u4ece\u5de6\u8d77\uff1aMargarita Behrens \u548c Joseph Ecker<br \/><a href=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500.jpg\">\u70b9\u51fb\u6b64\u5904<\/a> \u7528\u4e8e\u9ad8\u5206\u8fa8\u7387\u56fe\u50cf\u3002.<br \/>\u7248\u6743\uff1a\u8428\u514b\u7814\u7a76\u6240<\/figcaption><\/figure>\n<p>\u201c\u6211\u4eec\u5f00\u53d1\u7684\u8111\u56fe\u8c31\u53ef\u4ee5\u5e2e\u52a9\u75be\u75c5\u7814\u7a76\u4eba\u5458\u627e\u5230\u6b63\u786e\u7684\u65b9\u5411\u2014\u2014\u4f8b\u5982\uff0c\u6211\u4eec\u53ef\u4ee5\u8bf4\u2018\u57fa\u56e0\u7ec4\u4e2d\u7684\u90a3\u4e2a\u533a\u57df\uff0c\u5728\u90a3\u4e00\u5c0f\u90e8\u5206\u7279\u5b9a\u795e\u7ecf\u5143\u4e2d\uff0c\u5728\u5927\u8111\u7684\u90a3\u4e2a\u90e8\u5206\uff0c\u67d0\u4e2a\u5206\u5b50\u4e8b\u4ef6\u5931\u63a7\u5bfc\u81f4\u4e86\u90a3\u79cd\u75be\u75c5\u2019\uff0c\u201d\u8be5\u4e2d\u5fc3\u9886\u5bfc\u8005\u6559\u6388\u8bf4\u9053\u3002 <a href=\"https:\/\/www.salk.edu\/zh\/scientist\/joseph-ecker\/\">\u7ea6\u745f\u592b\u00b7\u57c3\u514b\u5c14<\/a>, \u7d22\u5c14\u514b\u7814\u7a76\u6240\u57fa\u56e0\u7ec4\u5206\u6790\u5b9e\u9a8c\u5ba4\u4e3b\u4efb\u3001\u970d\u534e\u5fb7\u00b7\u4f11\u65af\u533b\u5b66\u7814\u7a76\u6240\u7814\u7a76\u5458\u3002\u201c\u6700\u7ec8\uff0c\u8fd9\u4e9b\u4fe1\u606f\u53ef\u80fd\u6709\u52a9\u4e8e\u6211\u4eec\u8bbe\u8ba1\u57fa\u56e0\u7597\u6cd5\uff0c\u4f7f\u5176\u4ec5\u9776\u5411\u9700\u8981\u6cbb\u7597\u7684\u7ec6\u80de\u7fa4\u2014\u2014\u5728\u6b63\u786e\u7684\u65f6\u95f4\u5c06\u6b63\u786e\u7684\u57fa\u56e0\u8f93\u9001\u5230\u6b63\u786e\u7684\u4f4d\u7f6e\u3002\u201d<\/p>\n<p>\u9664\u57c3\u514b\u5c14\u5916\uff0c\u591a\u7ec4\u5b66\u4eba\u7c7b\u8111\u7ec6\u80de\u56fe\u8c31\u4e2d\u5fc3\u8fd8\u5305\u62ec <a href=\"https:\/\/www.salk.edu\/zh\/scientist\/margaritabehrens\/\">\u739b\u683c\u4e3d\u5854\u00b7\u8d1d\u4f26\u65af<\/a>, \u7684\u7814\u7a76\u6559\u6388\uff0c\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u7684 Bing Ren\uff0c\u52a0\u5dde\u5927\u5b66\u6b27\u6587\u5206\u6821\u7684 Xiangmin Xu\uff0c\u4ee5\u53ca\u5723\u8def\u6613\u65af\u534e\u76db\u987f\u5927\u5b66\u7684 Ting Wang\u3002.<\/p>\n<p>\u7d22\u5c14\u514b\u7814\u7a76\u6240\u5c06\u83b7\u5f97\u8be5\u4e2d\u5fc3\u7ea6 $7700 \u4e07\u7f8e\u5143\u7684\u8d44\u52a9\uff0c\u8fd9\u5c06\u662f\u8be5\u7814\u7a76\u6240\u5728 62 \u5e74\u5386\u53f2\u4e2d\u83b7\u5f97\u7684\u6700\u9ad8\u5355\u7b14\u62e8\u6b3e\u3002.<\/p>\n<p><strong>\u8d77\u59cb<\/strong><\/p>\n<p>\u56fd\u5bb6\u536b\u751f\u7814\u7a76\u9662\u65b0\u8111\u8ba1\u5212\u7ec6\u80de\u56fe\u8c31\u7f51\u7edc\uff08NIH\u2019s new BRAIN Initiative Cell Atlas Network\uff09\u7684\u7ec4\u6210\u90e8\u5206\uff0c\u591a\u7ec4\u5b66\u4eba\u7c7b\u8111\u7ec6\u80de\u56fe\u8c31\u4e2d\u5fc3\uff0c\u662f\u5728\u5bf9\u5c0f\u9f20\u5927\u8111\u8fdb\u884c\u4e94\u5e74\u6d4b\u7ed8\u5de5\u4f5c\u7684\u57fa\u7840\u4e0a\u5efa\u7acb\u7684\uff0c\u8be5\u9879\u76ee\u66fe\u88ab\u79f0\u4e3a\u8111\u8ba1\u5212\u7ec6\u80de\u666e\u67e5\u7f51\u7edc\uff08BRAIN Initiative Cell Census Network\uff09\u3002\u4e00\u672c\u7279\u520a <em>\u81ea\u7136 <\/em>2021\u5e7410\u6708\u51fa\u7248 <a href=\"https:\/\/www.salk.edu\/zh\/news-release\/salk-teams-advance-efforts-to-treat-prevent-and-cure-brain-disorders-via-nih-brain-atlas\/\">\u63cf\u8ff0\u4e86\u8be5\u52aa\u529b\u7684\u7ed3\u679c<\/a>, \u5305\u62ec\u4e0d\u540c\u7ec6\u80de\u7c7b\u578b\u5728\u6574\u4e2a\u5c0f\u9f20\u5927\u8111\u4e2d\u7684\u7ec4\u7ec7\u548c\u8fde\u63a5\u65b9\u5f0f\u3002.<\/p>\n<p>\u201c\u5c31\u50cf\u6211\u4eec\u901a\u8fc7\u77ed\u6682\u7684\u767b\u6708\u65c5\u884c\u4e86\u89e3\u4e86\u592a\u7a7a\u65c5\u884c\u4e00\u6837\uff0c\u5c0f\u9f20\u5927\u8111\u7ed8\u56fe\u9879\u76ee\u8ba9\u6211\u4eec\u6df1\u523b\u7406\u89e3\u4e86\u5982\u4f55\u7740\u624b\u7814\u7a76\u66f4\u5927\u7684\u4eba\u7c7b\u5927\u8111\uff0c\u4ee5\u53ca\u8981\u771f\u6b63\u7ed8\u5236\u51fa\u4eba\u7c7b\u5927\u8111\u56fe\u8c31\u6211\u4eec\u9700\u8981\u54ea\u4e9b\u7c7b\u578b\u7684\u57fa\u56e0\u7ec4\u4fe1\u606f\uff0c\u201dBehrens \u8bf4\u9053\u3002\u201c\u8fd9\u4e2a\u9879\u76ee\u662f\u79d1\u5b66\u4e2d\u56e2\u961f\u5408\u4f5c\u5bcc\u6709\u6210\u6548\u7684\u4e00\u4e2a\u4f8b\u5b50\u2014\u2014\u8fd9\u7c7b\u9879\u76ee\u65e0\u6cd5\u5728\u5355\u4e00\u5b9e\u9a8c\u5ba4\u5b8c\u6210\u3002\u201d<\/p>\n<figure id=\"attachment_35953\"  class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"271\" class=\"img-responsive wp-image-35953 size-medium\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/BIAN_MERFISH-hr-300x271.jpg\" alt=\"A cross-section of the middle temporal gyrus region of a male human brain that uses spatial transcriptomics, a technique that distinguishes cells by their genetic data and uses that information to map the cells back to their original locations. Credit: Salk Institute and UC San Diego\" srcset=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/BIAN_MERFISH-hr-300x271.jpg 300w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/BIAN_MERFISH-hr-147x133.jpg 147w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/BIAN_MERFISH-hr-458x413.jpg 458w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/BIAN_MERFISH-hr-400x361.jpg 400w, https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/BIAN_MERFISH-hr.jpg 539w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption class=\"wp-caption-text\">\u4e00\u4e2a\u7537\u6027\u4eba\u8111\u4e2d\u989e\u4e2d\u56de\u533a\u57df\u7684\u6a2a\u622a\u9762\uff0c\u4f7f\u7528\u4e86\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u5b66\u6280\u672f\uff0c\u8be5\u6280\u672f\u901a\u8fc7\u57fa\u56e0\u6570\u636e\u533a\u5206\u7ec6\u80de\uff0c\u5e76\u5229\u7528\u8fd9\u4e9b\u4fe1\u606f\u5c06\u7ec6\u80de\u91cd\u65b0\u5b9a\u4f4d\u5230\u5176\u539f\u59cb\u4f4d\u7f6e\u3002.<br \/><a href=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/BIAN_MERFISH-hr.jpg\">\u70b9\u51fb\u6b64\u5904<\/a> \u7528\u4e8e\u9ad8\u5206\u8fa8\u7387\u56fe\u50cf\u3002.<br \/>\u5b66\u5206\uff1a\u7d22\u5c14\u514b\u7814\u7a76\u6240\u548c\u52a0\u5dde\u5927\u5b66\u5723\u8fed\u6208\u5206\u6821<\/figcaption><\/figure>\n<p><strong>\u7ed8\u5236\u4eba\u8111\u56fe<\/strong><\/p>\n<p>\u5728\u4eba\u7c7b\u591a\u7ec4\u5b66\u8111\u7ec6\u80de\u56fe\u8c31\u4e2d\u5fc3\uff0c\u7814\u7a76\u4eba\u5458\u5c06\u68c0\u67e5 1500 \u4e2a\u8111\u6837\u672c\uff0830 \u4e2a\u4eba\u8111\uff0c\u5e74\u9f84\u8303\u56f4\u4e0d\u540c\uff0c\u6bcf\u4e2a\u8111\u5305\u542b 50 \u4e2a\u533a\u57df\uff09\u3002\u8be5\u4e2d\u5fc3\u4e3b\u8981\u5173\u6ce8\u8868\u89c2\u9057\u4f20\u5b66\u2014\u2014\u5373\u5206\u5b50\u4e8b\u4ef6\uff0c\u5b83\u4eec\u4f1a\u5f71\u54cd\u5728\u7279\u5b9a\u7ec6\u80de\u7c7b\u578b\u6216\u7279\u5b9a\u65f6\u95f4\u57fa\u56e0\u662f\u201c\u5f00\u542f\u201d\u8fd8\u662f\u201c\u5173\u95ed\u201d\u2014\u2014\u800c\u4e0d\u662f\u6bcf\u4e2a\u7ec6\u80de\u7684\u57fa\u56e0\u5e8f\u5217\u3002\u8be5\u4e2d\u5fc3\u8fd8\u5c06\u8003\u8651\u54ea\u4e9b\u7ec6\u80de\u4f4d\u4e8e\u4f55\u5904\u3002Ecker \u8bf4\uff0c\u4f4d\u7f6e\u5f88\u91cd\u8981\uff0c\u56e0\u4e3a\u7ec6\u80de\u4e4b\u95f4\u4f1a\u76f8\u4e92\u4ea4\u6d41\u3002.<\/p>\n<p>\u52a0\u5dde\u5927\u5b66\u6b27\u6587\u5206\u6821\u7684\u56e2\u961f\u6210\u5458\u5c06\u4e3b\u8981\u8d1f\u8d23\u8111\u6837\u672c\u7684\u91c7\u96c6\u3002\u7d22\u5c14\u514b\u7814\u7a76\u6240\u7684\u79d1\u5b66\u5bb6\u5c06\u5206\u79bb\u6bcf\u4e2a\u533a\u57df\u4e2d\u6bcf\u4e2a\u5355\u72ec\u7ec6\u80de\u7684\u7ec6\u80de\u6838\uff0c\u5e76\u8bb0\u5f55\u5206\u5b50\u7ec6\u8282\uff0c\u4f8b\u5982\u67d3\u8272\u8d28\u7ed3\u6784\u548c DNA \u7532\u57fa\u5316\uff08\u5373\u67d3\u8272\u4f53\u7684\u4e09\u7ef4\u7ed3\u6784\u4ee5\u53ca\u5b83\u4eec\u5982\u4f55\u88ab\u5316\u5b66\u6807\u7b7e\u4fee\u9970\uff09\u3002\u5728\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\uff0cRen \u5b9e\u9a8c\u5ba4\u5c06\u7814\u7a76\u67d3\u8272\u8d28\u4fee\u9970\u548c\u57fa\u56e0\u8868\u8fbe\u3002.<\/p>\n<p>\u201c\u672c\u8d28\u4e0a\uff0c\u6211\u4eec\u60f3\u63d0\u53d6\u6570\u767e\u4e07\u3001\u751a\u81f3\u6570\u4ebf\u4e2a\u8111\u7ec6\u80de\uff0c\u6df1\u5165\u4e86\u89e3\u5b83\u4eec\u7684\u8868\u89c2\u9057\u4f20\u5b66\u4ee5\u53ca\u67d3\u8272\u8d28\u7684\u6392\u5217\u65b9\u5f0f\uff0c\u5e76\u5c06\u5176\u7f6e\u4e8e\u7a7a\u95f4\u80cc\u666f\u4e0b\uff0c\u4ee5\u4fbf\u6211\u4eec\u80fd\u591f\u770b\u5230\u8fd9\u4e9b\u7ec6\u80de\u7684\u201d\u4f4f\u6240\u2019\uff0c\u5e76\u7406\u89e3\u4efb\u4f55\u5927\u8111\u533a\u57df\u4e2d\u7684\u6240\u6709\u7ec6\u80de\u662f\u5982\u4f55\u7ec4\u7ec7\u8d77\u6765\u7684\uff0c\u4ee5\u53ca\u5728\u4efb\u4f55\u5e74\u9f84\u6bb5\u7684\u60c5\u51b5\u3002\u201d\u5c24\u514b\u5c14\u8bf4\uff0c\u4ed6\u540c\u65f6\u8fd8\u662f\u7d22\u5c14\u514b\u56fd\u9645\u9057\u4f20\u5b66\u59d4\u5458\u4f1a\u4e3b\u5e2d\u3002.<\/p>\n<p>\u201c\u76ee\u524d\uff0c\u6211\u4eec\u51e0\u4e4e\u6ca1\u6709\u5173\u4e8e\u4eba\u8111\u7684\u6b64\u7c7b\u6570\u636e\u3002\u201d<\/p>\n<p><strong>\u6280\u672f\u4e0e\u6570\u636e<\/strong><\/p>\n<p>\u901a\u5e38\uff0c\u5f53\u7814\u7a76\u4eba\u5458\u7814\u7a76\u5355\u4e2a\u7ec6\u80de\u65f6\uff0c\u8be5\u7ec6\u80de\u4f1a\u4ece\u5927\u8111\u7684\u5176\u4ed6\u90e8\u5206\u5206\u79bb\u51fa\u6765\uff0c\u8fd9\u9650\u5236\u4e86\u53ef\u4ee5\u5f97\u51fa\u7684\u7ed3\u8bba\u3002\u4e3a\u4e86\u514b\u670d\u8fd9\u4e00\u70b9\uff0cEcker \u7684\u56e2\u961f\u5c06\u4f7f\u7528\u4e00\u79cd\u79f0\u4e3a\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u5b66\u7684\u65b0\u6280\u672f\uff0c\u901a\u8fc7\u57fa\u56e0\u6570\u636e\u6765\u533a\u5206\u7ec6\u80de\uff0c\u5e76\u5229\u7528\u8fd9\u4e9b\u4fe1\u606f\u5c06\u7ec6\u80de\u6620\u5c04\u56de\u5176\u539f\u59cb\u4f4d\u7f6e\u3002.<\/p>\n<p>\u8be5\u56e2\u961f\u5c06\u5e94\u7528\u7684\u8bb8\u591a\u5176\u4ed6\u6280\u672f\u90fd\u662f\u7531\u7814\u7a76\u4eba\u5458\u81ea\u5df1\u5f00\u53d1\u7684\u3002\u4f8b\u5982\uff0c\u57c3\u514b\u5c14\u7684\u56e2\u961f\u82b1\u4e86\u4e94\u5e74\u65f6\u95f4\u5f00\u53d1 <a href=\"https:\/\/www.salk.edu\/zh\/news-release\/new-technology-enables-unprecedented-glimpse-inside-single-brain-cells\/\">snmCATseq<\/a>, \u4e00\u79cd\u80fd\u591f\u540c\u65f6\u5206\u6790\u6765\u81ea\u5355\u4e2a\u7ec6\u80de\u7684 DNA\u3001RNA \u548c\u5f00\u653e\u67d3\u8272\u8d28\u7684\u6280\u672f\u3002.<\/p>\n<p>Ecker \u4f30\u8ba1\uff0c\u4ec5\u4ed6\u6240\u5728\u7684\u5b9e\u9a8c\u5ba4\u5728\u8fd9\u4e2a\u9879\u76ee\u671f\u95f4\u5c31\u5c06\u4ea7\u751f 11 PB \u7684\u539f\u59cb\u6570\u636e\uff0c\u76f8\u5f53\u4e8e 171,875 \u4e2a\uff08\u6bcf\u4e2a 64GB \u7684\uff09U \u76d8\uff0c\u8fd9\u51f8\u663e\u4e86\u8be5\u4e2d\u5fc3\u5728\u8ba1\u7b97\u751f\u7269\u5b66\u3001\u6570\u636e\u5b58\u50a8\u548c\u5206\u6790\u65b9\u9762\u7684\u4e13\u4e1a\u77e5\u8bc6\u548c\u8d44\u6e90\u3002\u534e\u76db\u987f\u5927\u5b66\u7684\u56e2\u961f\u6210\u5458\u5c06\u8d1f\u8d23\u6570\u636e\u7ba1\u7406\u548c\u96c6\u6210\u3002.<\/p>\n<p>\u201c\u968f\u7740BICAN\u5956\u9879\u7684\u5ba3\u5e03\uff0c\u6211\u4eec\u6b63\u5728 BRAIN Initiative \u7ec6\u80de\u666e\u67e5\u9879\u76ee\uff08\u59cb\u4e8e 2014 \u5e74\uff09\u7684\u6574\u4f53\u4e0a\u8fce\u6765\u4e00\u4e2a\u6fc0\u52a8\u4eba\u5fc3\u7684\u8f6c\u578b\uff0c\u201dNIH BRAIN Initiative \u4e3b\u4efb John Ngai \u8bf4\u3002\u201c\u8fd9\u4e9b\u5956\u9879\u5c06\u4f7f\u7814\u7a76\u4eba\u5458\u80fd\u591f\u4ee5\u524d\u6240\u672a\u6709\u7684\u7ec6\u8282\u548c\u89c4\u6a21\u63a2\u7d22\u4eba\u8111\u4e2d\u8d85\u8fc7 2000 \u4ebf\u4e2a\u795e\u7ecf\u5143\u548c\u975e\u795e\u7ecf\u5143\u7684\u590d\u6742\u7279\u5f81\u2014\u2014\u8fd9\u662f\u4e00\u9879\u5148\u8fdb\u6280\u672f\u548c\u8de8\u56e2\u961f\u7814\u7a76\u5408\u4f5c\u7684\u58ee\u4e3e\uff0c\u5b83\u5c06\u63ed\u793a\u7406\u89e3\u7279\u5b9a\u8111\u7ec6\u80de\u7fa4\u4f53\u7684\u75c5\u7406\u6027\u53d8\u5316\u5982\u4f55\u5bfc\u81f4\u795e\u7ecf\u548c\u795e\u7ecf\u7cbe\u795e\u75be\u75c5\u7684\u65b0\u8303\u5f0f\u3002\u201d.<\/p>\n<p><strong>\u5173\u4e8e NIH \u8111\u8ba1\u5212\uff1a<\/strong><\/p>\n<p>\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662 <em>\u8111\u7814\u7a76\u901a\u8fc7\u63a8\u8fdb\u521b\u65b0\u795e\u7ecf\u6280\u672f<\/em> (BRAIN) Initiative \u662f\u4e00\u9879\u65e8\u5728\u6df1\u5316\u5bf9\u4eba\u7c7b\u601d\u7ef4\u5185\u5728\u8fd0\u4f5c\u7684\u7406\u89e3\uff0c\u5e76\u6539\u5584\u6211\u4eec\u6cbb\u7597\u3001\u9884\u9632\u548c\u6cbb\u6108\u5927\u8111\u75be\u75c5\u65b9\u5f0f\u7684\u5b8f\u5927\u8ba1\u5212\u3002\u81ea 2014 \u5e74\u9996\u6b21\u83b7\u5f97\u8d44\u52a9\u4ee5\u6765\uff0cBRAIN Initiative \u5df2\u62e8\u6b3e\u8d85\u8fc7 $24 \u4ebf\u7f8e\u5143\u7528\u4e8e\u7814\u7a76\u3002BRAIN \u7ec6\u80de\u666e\u67e5\u7f51\u7edc\uff08\u5c0f\u9f20\u5927\u8111\u56fe\u8c31\uff09\u548c BRAIN \u7ec6\u80de\u56fe\u8c31\u7f51\u7edc\uff08\u4eba\u7c7b\u5927\u8111\u56fe\u8c31\uff09\u662f BRAIN Initiative \u7684\u7ec4\u6210\u90e8\u5206\u3002.<\/p>\n<p><strong>\u5173\u4e8e\u7d22\u5c14\u514b\u751f\u7269\u7814\u7a76\u6240\uff1a<\/strong><\/p>\n<p>\u6bcf\u4e00\u4e2a\u6cbb\u6108\u90fd\u6709\u4e00\u4e2a\u8d77\u70b9\u3002\u201c\u8428\u5c14\u514b\u7814\u7a76\u6240\u201d\u4f53\u73b0\u4e86\u4e54\u7eb3\u65af\u00b7\u7d22\u5c14\u514b\u7684\u4f7f\u547d\u2014\u2014\u6562\u4e8e\u5c06\u68a6\u60f3\u53d8\u4e3a\u73b0\u5b9e\u3002\u5176\u4eab\u8a89\u56fd\u9645\u5e76\u5c61\u83b7\u6b8a\u8363\u7684\u79d1\u5b66\u5bb6\u4eec\u63a2\u7d22\u751f\u547d\u7684\u6839\u57fa\uff0c\u5728\u795e\u7ecf\u79d1\u5b66\u3001\u9057\u4f20\u5b66\u3001\u514d\u75ab\u5b66\u3001\u690d\u7269\u751f\u7269\u5b66\u7b49\u9886\u57df\u5bfb\u6c42\u65b0\u7684\u8ba4\u8bc6\u3002\u8be5\u7814\u7a76\u6240\u662f\u4e00\u4e2a\u72ec\u7acb\u7684\u975e\u8425\u5229\u7ec4\u7ec7\uff0c\u4e5f\u662f\u4e00\u5ea7\u6807\u5fd7\u6027\u7684\u5efa\u7b51\uff1a\u6709\u610f\u8bc6\u5730\u9009\u62e9\u5c0f\u578b\u5316\uff0c\u5176\u672c\u8d28\u662f\u4eb2\u5bc6\u7684\uff0c\u5e76\u4e14\u65e0\u6240\u754f\u60e7\u5730\u9762\u5bf9\u4efb\u4f55\u6311\u6218\u3002\u65e0\u8bba\u662f\u764c\u75c7\u8fd8\u662f\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff0c\u8870\u8001\u8fd8\u662f\u7cd6\u5c3f\u75c5\uff0c\u201c\u7d22\u5c14\u514b\u201d\u90fd\u662f\u6cbb\u6108\u7684\u8d77\u70b9\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1asalk.edu\u3002.<\/p>","protected":false},"featured_media":0,"template":"","faculty":[42,354],"disease-research":[279,333,124],"class_list":["post-35950","disclosure","type-disclosure","status-publish","hentry","faculty-joseph-ecker","faculty-margaritabehrens","disease-research-awards","disease-research-genetics","disease-research-neuroscience-and-neurological-disorders"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Salk Institute to lead $126 million effort to map the aging human brain - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/zh\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Salk Institute to lead $126 million effort to map the aging human brain - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"LA JOLLA\u2014With a five-year, $126 million grant from the National Institutes of Health (NIH), a team led by Salk Institute scientists has launched a new Center for Multiomic Human Brain Cell Atlas. Part of the NIH\u2019s Brain Research Through Advancing Innovative Neurotechnologies\u00ae (BRAIN) Initiative, the project aims to describe the cells that make up the human brain in unprecedented molecular detail, classify brain cells into more precise subtypes, and pinpoint the location of each cell in the brain. What\u2019s more, the team will track how these features change from early to late life.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.salk.edu\/zh\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/\" \/>\n<meta property=\"og:site_name\" content=\"Salk Institute for Biological Studies\" \/>\n<meta property=\"article:modified_time\" content=\"2022-09-22T15:00:37+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-300x200.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\\\/\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\\\/\",\"name\":\"Salk Institute to lead $126 million effort to map the aging human brain - Salk Institute for Biological Studies\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\\\/#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2022\\\/09\\\/Marga_Behrens_Joe_Ecker1500-300x200.jpg\",\"datePublished\":\"2022-09-22T07:00:02+00:00\",\"dateModified\":\"2022-09-22T15:00:37+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\\\/#breadcrumb\"},\"inLanguage\":\"zh-CN\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-CN\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\\\/#primaryimage\",\"url\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2022\\\/09\\\/Marga_Behrens_Joe_Ecker1500-300x200.jpg\",\"contentUrl\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2022\\\/09\\\/Marga_Behrens_Joe_Ecker1500-300x200.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.salk.edu\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Salk Institute to lead $126 million effort to map the aging human brain\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"name\":\"Salk Institute for Biological Studies\",\"description\":\"The Power of Science\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.salk.edu\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"zh-CN\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\",\"name\":\"Salk Institute for Biological Studies\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-CN\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"contentUrl\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"width\":696,\"height\":696,\"caption\":\"Salk Institute for Biological Studies\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Salk Institute to lead $126 million effort to map the aging human brain - Salk Institute for Biological Studies","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.salk.edu\/zh\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/","og_locale":"zh_CN","og_type":"article","og_title":"Salk Institute to lead $126 million effort to map the aging human brain - Salk Institute for Biological Studies","og_description":"LA JOLLA\u2014With a five-year, $126 million grant from the National Institutes of Health (NIH), a team led by Salk Institute scientists has launched a new Center for Multiomic Human Brain Cell Atlas. Part of the NIH\u2019s Brain Research Through Advancing Innovative Neurotechnologies\u00ae (BRAIN) Initiative, the project aims to describe the cells that make up the human brain in unprecedented molecular detail, classify brain cells into more precise subtypes, and pinpoint the location of each cell in the brain. What\u2019s more, the team will track how these features change from early to late life.","og_url":"https:\/\/www.salk.edu\/zh\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/","og_site_name":"Salk Institute for Biological Studies","article_modified_time":"2022-09-22T15:00:37+00:00","og_image":[{"url":"http:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-300x200.jpg","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.salk.edu\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/","url":"https:\/\/www.salk.edu\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/","name":"Salk Institute to lead $126 million effort to map the aging human brain - Salk Institute for Biological Studies","isPartOf":{"@id":"https:\/\/www.salk.edu\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.salk.edu\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/#primaryimage"},"image":{"@id":"https:\/\/www.salk.edu\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/#primaryimage"},"thumbnailUrl":"http:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-300x200.jpg","datePublished":"2022-09-22T07:00:02+00:00","dateModified":"2022-09-22T15:00:37+00:00","breadcrumb":{"@id":"https:\/\/www.salk.edu\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/#breadcrumb"},"inLanguage":"zh-CN","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.salk.edu\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/"]}]},{"@type":"ImageObject","inLanguage":"zh-CN","@id":"https:\/\/www.salk.edu\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/#primaryimage","url":"http:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-300x200.jpg","contentUrl":"http:\/\/www.salk.edu\/wp-content\/uploads\/2022\/09\/Marga_Behrens_Joe_Ecker1500-300x200.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/www.salk.edu\/news-release\/salk-institute-to-lead-126-million-effort-to-map-the-aging-human-brain\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.salk.edu\/"},{"@type":"ListItem","position":2,"name":"Salk Institute to lead $126 million effort to map the aging human brain"}]},{"@type":"WebSite","@id":"https:\/\/www.salk.edu\/#website","url":"https:\/\/www.salk.edu\/","name":"\u7d22\u5c14\u514b\u751f\u7269\u7814\u7a76\u6240","description":"\u79d1\u5b66\u7684\u529b\u91cf","publisher":{"@id":"https:\/\/www.salk.edu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.salk.edu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"zh-CN"},{"@type":"Organization","@id":"https:\/\/www.salk.edu\/#organization","name":"\u7d22\u5c14\u514b\u751f\u7269\u7814\u7a76\u6240","url":"https:\/\/www.salk.edu\/","logo":{"@type":"ImageObject","inLanguage":"zh-CN","@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/","url":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","contentUrl":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","width":696,"height":696,"caption":"Salk Institute for Biological Studies"},"image":{"@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/"}}]}},"ACF":{"paper_url":"","journal_title":"","paper_author_list":"","doi":"","paper_title":"","subhead":"Largest grant in Salk history establishes new Center for Multiomic Human Brain Cell Atlas to detail the many individual cells that make up the human brain\u2014their molecular features, where they are found and how they change with age","home_photo":"","listing_photo":"","legacy_boilerplate":[],"hide_boilerplate":["Hide"],"disable_date":false,"listing_excerpt":"","descriptive_blurb":"","has_journal_cover":false,"og_image_override":false,"gallery":false},"_links":{"self":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/disclosure\/35950","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/disclosure"}],"about":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/types\/disclosure"}],"version-history":[{"count":13,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/disclosure\/35950\/revisions"}],"predecessor-version":[{"id":36147,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/disclosure\/35950\/revisions\/36147"}],"wp:attachment":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/media?parent=35950"}],"wp:term":[{"taxonomy":"faculty","embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/faculty?post=35950"},{"taxonomy":"disease-research","embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/disease-research?post=35950"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}