{"id":2540,"date":"2015-05-28T00:00:00","date_gmt":"2015-05-28T07:00:00","guid":{"rendered":"https:\/\/vermont.salk.edu\/news-release\/salk-recruits-human-geneticist-graham-mcvicker\/"},"modified":"2015-10-04T12:06:34","modified_gmt":"2015-10-04T19:06:34","slug":"salk-recruits-human-geneticist-graham-mcvicker","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/zh\/news-release\/salk-recruits-human-geneticist-graham-mcvicker\/","title":{"rendered":"Salk recruits human geneticist Graham McVicker"},"content":{"rendered":"<p>\nLA JOLLA\u2013Expanding on its leadership in genetics, the Salk Institute is pleased to announce the appointment of Graham McVicker as an assistant professor in the Center for Integrative Biology and in the Laboratory of Genetics.\n<\/p>\n<div class=\"imageCaption\"><img decoding=\"async\" style=\"border-bottom: 1px #006699 solid;\" alt=\"Graham McVicker\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/01\/2086-mcvicker.jpg\"><\/p>\n<p>Graham McVicker<\/p>\n<p><a target=\"_blank\" href=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2015\/02\/2086-mcvicker.jpg\">Click here<\/a> for a high-resolution image.<\/p>\n<p>\nImage: Courtesy of the Salk Institute for Biological Studies\n<\/p>\n<\/div>\n<p>\n\u201cGraham is a forward-thinking researcher with an impressive background in developing and harnessing innovative techniques to help unravel the human genome,\u201d says <a href=\"https:\/\/www.salk.edu\/zh\/faculty\/gage.html\/\">\u9c81\u65af\u8482\u00b7\u76d6\u5947<\/a>, acting president of the Institute. \u201cUnderstanding and analyzing human genetic diversity is crucial to both science and medicine, and Graham\u2019s breadth of expertise in computing and genetics will spur important innovations in these areas.\u201d\n<\/p>\n<p>\nMcVicker will join the Salk Institute in January 2016. He seeks to understand how human genetic variation affects molecular processes in the cell and contributes to disease.\n<\/p>\n<p>\nGeneticists have cataloged millions of genetic differences between individuals, but it is difficult to determine which of them affect human traits such as height, blood pressure and disease risk. McVicker has begun to tackle this problem by developing powerful statistical and computational approaches to analyze the human genome and determine the molecular function of individual genetic variants.\n<\/p>\n<p>\nMcVicker is particularly interested in genetic variants that affect chromatin. Chromatin is the molecular packaging that organizes DNA and regulates access to the genome, which helps control which genes are turned on in specific cells. Genetic variants that affect chromatin are likely to be important for many human diseases and the McVicker laboratory will focus specifically on those that affect chromatin in immune cells. By understanding these variants and linking them to disease risk, his laboratory will illuminate why some individuals are more susceptible to autoimmune and infectious diseases.\n<\/p>\n<p>\n\u201cI plan to push the boundaries of quantitative genetics and use genetic variation as a tool to understand the molecular processes that underlie human disease,\u201d says McVicker. \u201cI am excited to join the world-renowned faculty at the Salk Institute, where I will have the intellectual freedom, resources and collaborations to make important contributions in these areas.\u201d\n<\/p>\n<p>\nMcVicker earned his BS from the <a href=\"https:\/\/www.ubc.ca\/\" target=\"_blank\">University of British Columbia<\/a> in computer science and PhD from the <a href=\"http:\/\/www.washington.edu\/\" target=\"_blank\">University of Washington<\/a> in genome sciences, where he studied how selection and mutation shape genetic variation in primate evolution. More recently, he conducted postdoctoral research at the <a href=\"http:\/\/www.uchicago.edu\/\" target=\"_blank\">University of Chicago<\/a>, <a href=\"https:\/\/www.stanford.edu\/\" target=\"_blank\">Stanford University<\/a> and the <a href=\"http:\/\/www.dana-farber.org\/\" target=\"_blank\">Dana-Farber Cancer Institute<\/a>, where he developed new methods for genetic mapping of molecular quantitative traits.\n<\/p>\n<p><strong>About the Salk Institute for Biological Studies:<\/strong><br \/>\nThe Salk Institute for Biological Studies is one of the world&#8217;s preeminent basic research institutions, where internationally renowned faculty probes fundamental life science questions in a unique, collaborative and creative environment. Focused both on discovery and on mentoring future generations of researchers, Salk scientists make groundbreaking contributions to our understanding of cancer, aging, Alzheimer&#8217;s, diabetes and infectious diseases by studying neuroscience, genetics, cell and plant biology, and related disciplines.\n<\/p>\n<p>\nFaculty achievements have been recognized with numerous honors, including Nobel Prizes and memberships in the National Academy of Sciences. Founded in 1960 by polio vaccine pioneer Jonas Salk, MD, the Institute is an independent nonprofit organization and architectural landmark.<\/p>","protected":false},"featured_media":0,"template":"","faculty":[99],"disease-research":[],"class_list":["post-2540","disclosure","type-disclosure","status-publish","hentry","faculty-graham-mcvicker"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Salk recruits human geneticist Graham McVicker - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/zh\/news-release\/salk-recruits-human-geneticist-graham-mcvicker\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Salk recruits human geneticist Graham McVicker - 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