{"id":24736,"date":"2019-10-31T08:45:22","date_gmt":"2019-10-31T15:45:22","guid":{"rendered":"https:\/\/vermont.salk.edu\/?post_type=disclosure&#038;p=24736"},"modified":"2024-01-30T14:46:22","modified_gmt":"2024-01-30T22:46:22","slug":"unlocking-the-black-box-of-embryonic-development","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/zh\/news-release\/unlocking-the-black-box-of-embryonic-development\/","title":{"rendered":"\u89e3\u9501\u80da\u80ce\u53d1\u80b2\u7684\u9ed1\u7bb1"},"content":{"rendered":"<p>\u62c9\u970d\u4e9a\u2014\u5173\u4e8e\u7075\u957f\u7c7b\u52a8\u7269\u65e9\u671f\u80da\u80ce\u53d1\u80b2\u8fc7\u7a0b\u4e2d\u53d1\u751f\u7684\u5206\u5b50\u548c\u7ec6\u80de\u4e8b\u4ef6\uff0c\u76ee\u524d\u77e5\u4e4b\u751a\u5c11\u3002\u73b0\u5728\uff0c\u4e00\u4e2a\u7531\u4e2d\u7f8e\u4e24\u56fd\u79d1\u5b66\u5bb6\u7ec4\u6210\u7684\u56fd\u9645\u77e5\u540d\u56e2\u961f\u521b\u9020\u4e86\u4e00\u79cd\u65b9\u6cd5\uff0c\u80fd\u591f\u6bd4\u4ee5\u5f80\u4efb\u4f55\u65f6\u5019\u90fd\u8ba9\u7075\u957f\u7c7b\u52a8\u7269\u80da\u80ce\u5728\u5b9e\u9a8c\u5ba4\u4e2d\u53d1\u80b2\u66f4\u957f\u65f6\u95f4\uff0c\u4ece\u800c\u4f7f\u7814\u7a76\u4eba\u5458\u80fd\u591f\u9996\u6b21\u83b7\u5f97\u5173\u952e\u53d1\u80b2\u8fc7\u7a0b\u7684\u5206\u5b50\u7ec6\u8282\u3002\u8fd9\u9879\u7814\u7a76\u867d\u7136\u662f\u5728\u975e\u4eba\u7c7b\u7075\u957f\u7c7b\u7ec6\u80de\u4e2d\u8fdb\u884c\u7684\uff0c\u4f46\u5bf9\u4eba\u7c7b\u65e9\u671f\u53d1\u80b2\u5177\u6709\u76f4\u63a5\u610f\u4e49\u3002.<\/p>\n<figure id=\"attachment_24746\"  class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" width=\"458\" height=\"458\" class=\"img-responsive wp-image-24746 size-col-md-5\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-458x458.jpg\" alt=\"Pictured is Day 17 of a cultured primate embryo; the various colors indicate markers of cellular differentiation (specialization).\" srcset=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-458x458.jpg 458w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-150x150.jpg 150w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-300x300.jpg 300w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-768x768.jpg 768w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-767x767.jpg 767w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-147x147.jpg 147w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-585x585.jpg 585w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-553x553.jpg 553w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-750x750.jpg 750w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-945x945.jpg 945w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-400x400.jpg 400w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr-200x200.jpg 200w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr.jpg 1024w\" sizes=\"auto, (max-width: 458px) 100vw, 458px\" \/><figcaption class=\"wp-caption-text\">\u56fe\u4e2d\u662f\u57f9\u517b\u7684\u7075\u957f\u7c7b\u52a8\u7269\u80da\u80ce\u7684\u7b2c17\u5929\uff1b\u4e0d\u540c\u7684\u989c\u8272\u8868\u793a\u7ec6\u80de\u5206\u5316\uff08\u7279\u5316\uff09\u7684\u6807\u8bb0\u3002.<\/p>\n<p><a href=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Kunming-University-pr.jpg\">\u70b9\u51fb\u6b64\u5904<\/a> \u7528\u4e8e\u9ad8\u5206\u8fa8\u7387\u56fe\u50cf\u3002.<\/p>\n<p>\u9e23\u8c22\uff1aWeizhi Ji\/\u6606\u660e\u7406\u5de5\u5927\u5b66<\/figcaption><\/figure>\n<p>\u7814\u7a76\u53d1\u73b0\uff0c\u53d1\u8868\u4e8e <a href=\"https:\/\/science.sciencemag.org\/content\/early\/2019\/10\/30\/science.aaw5754\" target=\"_blank\" rel=\"noopener\"><em>\u79d1\u5b66<\/em><\/a> 2019\u5e7410\u670831\u65e5\uff0c\u4e3a\u65e9\u671f\u80da\u80ce\u53d1\u80b2\u63d0\u4f9b\u6709\u4ef7\u503c\u7684\u89c1\u89e3\uff0c\u5e76\u6709\u53ef\u80fd\u5e2e\u52a9\u6307\u5bfc\u4fc3\u8fdb\u4eba\u7c7b\u518d\u751f\u533b\u5b66\u7684\u65b9\u6cd5\u3002.<\/p>\n<p>\u201c\u6211\u4eec\u7684\u7814\u7a76\u9996\u6b21\u63ed\u793a\u4e86\u65e9\u671f\u53d1\u5c55\u7684\u8fd9\u4e2a\u9ed1\u5323\u5b50\uff0c\u201d\u8bf4 <a href=\"https:\/\/www.salk.edu\/zh\/scientist\/juan-carlos-izpisua-belmonte\/\">\u80e1\u5b89\u00b7\u5361\u6d1b\u65af\u00b7\u4f0a\u5179\u76ae\u82cf\u4e9a\u00b7\u8d1d\u5c14\u8499\u7279<\/a>, \uff0c\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff0c\u4e5f\u662fSalk\u57fa\u56e0\u8868\u8fbe\u5b9e\u9a8c\u5ba4\u7684\u6559\u6388\u3002\u201c\u6211\u4eec\u73b0\u5728\u53ef\u4ee5\u89c2\u5bdf\u7ec6\u80de\u5728\u80da\u80ce\u53d1\u80b2\u7684\u6bcf\u4e2a\u9636\u6bb5\u7684\u8fdb\u5c55\u60c5\u51b5\uff0c\u4ee5\u53ca\u5b83\u4eec\u53d1\u5c55\u6240\u9700\u7684\u56e0\u7d20\uff0c\u8fd9\u5c06\u6709\u52a9\u4e8e\u4e3a\u751f\u6210\u5404\u79cd\u7ec6\u80de\u548c\u7ec4\u7ec7\u63d0\u4f9b\u66f4\u597d\u7684\u9009\u62e9\u3002\u201d<\/p>\n<p>\u201c\u4e3a\u4e86\u7406\u89e3\u7075\u957f\u7c7b\u52a8\u7269\u539f\u80a0\u80da\u5f62\u6210\u80cc\u540e\u7684\u7ec6\u80de\u548c\u5206\u5b50\u673a\u5236\uff0c\u4e09\u5e74\u524d\u6211\u4eec\u5f00\u59cb\u5728\u4e2d\u56fd\u8fdb\u884c\u7334\u80da\u4f53\u5916\u57f9\u517b\u5b9e\u9a8c\u3002\u7531\u4e8e\u56e2\u961f\u5728\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u7cfb\u7edf\u6027\u7814\u7a76\u65b9\u9762\u62e5\u6709\u957f\u671f\u79ef\u7d2f\u7684\u4e13\u4e1a\u77e5\u8bc6\uff0c\u4ee5\u53ca\u5df2\u7ecf\u5efa\u7acb\u5b8c\u5584\u7684\u751f\u6b96\u7814\u7a76\u4f53\u7cfb\uff0c\u4f8b\u5982\u4f53\u5916\u53d7\u7cbe\u5e73\u53f0\uff0c\u6211\u4eec\u6210\u529f\u5730\u5b9e\u73b0\u4e86\u76ee\u6807\u3002\u8fd9\u6709\u52a9\u4e8e\u63ed\u793a\u4eba\u7c7b\u7740\u5e8a\u540e\u53d1\u80b2\u4e2d\u5148\u524d\u672a\u77e5\u7684\u65b9\u9762\u3002\u201d\u6606\u660e\u7406\u5de5\u5927\u5b66\u7075\u957f\u7c7b\u8f6c\u5316\u533b\u5b66\u7814\u7a76\u9662\u7684\u6559\u6388\u3001\u9662\u957f\u3001\u5171\u540c\u901a\u8baf\u4f5c\u8005\u5b63\u7ef4\u667a\u8bf4\u3002.<\/p>\n<p>\u79d1\u5b66\u5bb6\u4eec\u5e0c\u671b\u7814\u7a76\u4e00\u4e2a\u79f0\u4e3a\u539f\u80a0\u80da\u5f62\u6210\u7684\u65e9\u671f\u53d1\u80b2\u91cc\u7a0b\u7891\uff0c\u8fd9\u662f\u80da\u80ce\u53d1\u80b2\u8fc7\u7a0b\u4e2d\u8f6c\u53d8\u4e3a\u591a\u5c42\u7ed3\u6784\uff08\u79f0\u4e3a\u539f\u80a0\u80da\uff09\u7684\u9636\u6bb5\uff0c\u800c\u6240\u6709\u672a\u6765\u7684\u7ec4\u7ec7\u548c\u5668\u5b98\u90fd\u5c06\u7531\u6b64\u5206\u5316\u800c\u6765\u3002\u5176\u4e2d\u4e00\u5c42\u5c06\u53d1\u80b2\u6210\u80ba\u3001\u80c3\u80a0\u9053\u548c\u809d\u810f\uff1b\u53e6\u4e00\u5c42\u5c06\u53d1\u80b2\u6210\u5fc3\u810f\u3001\u808c\u8089\u548c\u751f\u6b96\u5668\u5b98\uff1b\u800c\u7b2c\u4e09\u5c42\u5c06\u53d1\u80b2\u6210\u76ae\u80a4\u548c\u795e\u7ecf\u7cfb\u7edf\u3002\u7136\u800c\uff0c\u7531\u4e8e\u5bf9\u65e9\u671f\u80da\u80ce\u7684\u83b7\u53d6\u9014\u5f84\u6709\u9650\uff0c\u79d1\u5b66\u5bb6\u4eec\u5e76\u4e0d\u4e86\u89e3\u539f\u80a0\u80da\u5f62\u6210\u5728\u7075\u957f\u7c7b\u52a8\u7269\u4e2d\u7684\u5206\u5b50\u548c\u7ec6\u80de\u9a71\u52a8\u56e0\u7d20\u3002.<\/p>\n<figure id=\"attachment_24740\"  class=\"wp-caption alignleft\"><a href=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500.jpg\"><img loading=\"lazy\" decoding=\"async\" width=\"458\" height=\"687\" class=\"img-responsive wp-image-24740 size-col-md-5\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-458x687.jpg\" alt=\"Juan Carlos Izpisua Belmonte\" srcset=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-458x687.jpg 458w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-200x300.jpg 200w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-768x1152.jpg 768w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-683x1024.jpg 683w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-147x221.jpg 147w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-300x450.jpg 300w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-585x878.jpg 585w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-553x830.jpg 553w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-750x1125.jpg 750w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-767x1151.jpg 767w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-945x1418.jpg 945w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-1250x1875.jpg 1250w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500-400x600.jpg 400w, https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500.jpg 1500w\" sizes=\"auto, (max-width: 458px) 100vw, 458px\" \/><\/a><figcaption class=\"wp-caption-text\">\u80e1\u5b89\u00b7\u5361\u6d1b\u65af\u00b7\u4f0a\u5179\u76ae\u82cf\u4e9a\u00b7\u8d1d\u5c14\u8499\u7279<\/p>\n<p><a href=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2019\/10\/Juan_Carlos_Belmonte_1500.jpg\">\u70b9\u51fb\u6b64\u5904<\/a> \u7528\u4e8e\u9ad8\u5206\u8fa8\u7387\u56fe\u50cf\u3002.<\/p>\n<p>\u7248\u6743\uff1a\u8428\u514b\u7814\u7a76\u6240<\/figcaption><\/figure>\n<p>\u201c\u6211\u4eec\u7684\u76ee\u6807\u662f\u5728\u65e9\u671f\u65f6\u95f4\u70b9\u57f9\u517b\u7075\u957f\u7c7b\u52a8\u7269\u80da\u80ce\uff0c\u4ee5\u7814\u7a76\u5176\u53d1\u80b2\u8fc7\u7a0b\uff0c\u201d\u8be5\u8bba\u6587\u7684\u5408\u8457\u8005\u3001\u5fb7\u514b\u8428\u65af\u5927\u5b66\u897f\u5357\u533b\u5b66\u4e2d\u5fc3\u52a9\u7406\u6559\u6388\u5434\u519b\uff08Jun Wu\uff09\u8bf4\u9053\u3002\u201c\u6211\u4eec\u5e0c\u671b\u6bcf\u5929\u76d1\u6d4b\u80da\u80ce\uff0c\u89c2\u5bdf\u5b83\u4eec\u7684\u5f62\u72b6\u3001\u5927\u5c0f\u548c\u8fc1\u79fb\u6a21\u5f0f\uff0c\u4ee5\u53ca\u5b83\u4eec\u5728\u7075\u957f\u7c7b\u65e9\u671f\u53d1\u80b2\u8fc7\u7a0b\u4e2d\u5982\u4f55\u751f\u6210\u4e0d\u540c\u7c7b\u578b\u7684\u7ec6\u80de\u3002\u201d<\/p>\n<p>\u4e3a\u4e86\u66f4\u597d\u5730\u7814\u7a76\u8fd9\u4e00\u5173\u952e\u8f6c\u5316\uff0c\u79d1\u5b66\u5bb6\u4eec\u4fee\u6539\u4e86\u5148\u524d\u5efa\u7acb\u7684\u80da\u80ce\u57f9\u517b\u65b9\u6848\uff0c\u4f7f\u65e9\u671f\u7075\u957f\u7c7b\u80da\u80ce\u80fd\u591f\u5728\u5b9e\u9a8c\u5ba4\u6761\u4ef6\u4e0b\u53d1\u80b2\u957f\u8fbe\u4e8c\u5341\u5929\uff1b\u6b64\u524d\u7814\u7a76\u4eba\u5458\u53ea\u80fd\u5728\u598a\u5a20\u7b2c\u4e8c\u5468\u4e4b\u524d\u7ef4\u6301\u57f9\u517b\u7684\u7075\u957f\u7c7b\u80da\u80ce\u3002\u5229\u7528\u65b0\u65b9\u6848\uff0c\u7814\u7a76\u56e2\u961f\u53d1\u73b0\u57f9\u517b\u80da\u80ce\u5185\u7684\u7ec6\u80de\u8868\u73b0\u51fa\u6e05\u6670\u7684\u5411\u539f\u80a0\u80da\u5404\u5c42\u53d1\u80b2\u7684\u8f68\u8ff9\uff0c\u7ed3\u679c\u63ed\u793a\u4e86\u4e00\u4e9b\u751f\u957f\u6240\u9700\u7684\u5206\u5b50\u7ec6\u8282\u3002\u8fd9\u4e9b\u6570\u636e\u8fd8\u53ef\u4ee5\u4f5c\u4e3a\u4e00\u9879\u8d44\u6e90\uff0c\u5e2e\u52a9\u5c06\u57f9\u517b\u80da\u80ce\u7684\u6301\u7eed\u65f6\u95f4\u5ef6\u957f\u81f3\u4e8c\u5341\u5929\u4ee5\u4e0a\uff0c\u4ee5\u4fbf\u66f4\u597d\u5730\u7814\u7a76\u5e72\u7ec6\u80de\u5206\u5316\uff08\u7279\u5316\uff09\u3002.<\/p>\n<p>\u201c\u8fd9\u4e9b\u7ed3\u679c\u9610\u91ca\u4e86\u8c03\u63a7\u7075\u957f\u7c7b\u52a8\u7269\u53d1\u80b2\u7684\u67d0\u4e9b\u8c03\u63a7\u7f51\u7edc\u548c\u4fe1\u53f7\u901a\u8def\uff0c\u201d Izpisua Belmonte \u8bf4\u9053\u3002\u201c\u8be5\u7cfb\u7edf\u4e3a\u5728\u5b9e\u9a8c\u5ba4\u4e2d\u5236\u5b9a\u66f4\u4f18\u7684\u7b56\u7565\u6765\u7814\u7a76\u7075\u957f\u7c7b\u65e9\u671f\u53d1\u80b2\uff08\u65e0\u8bba\u662f\u5728\u5065\u5eb7\u8fd8\u662f\u75be\u75c5\u72b6\u6001\u4e0b\uff09\u63d0\u4f9b\u4e86\u57fa\u7840\u548c\u8d44\u6e90\u3002\u201d<\/p>\n<p>\u5176\u4ed6\u4f5c\u8005\u5305\u62ec\u6606\u660e\u7406\u5de5\u5927\u5b66\u7684\u725b\u7389\u5b87\u3001\u5b59\u5ff5\u52e4\u3001\u674e\u660c\u3001\u53f8\u8fb0\u9633\u3001\u9b4f\u91d1\u5bbd\u3001\u5eb7\u745c\u3001\u53f8\u4f1f\u3001\u738b\u5b8f\u3001\u5f20E\u3001\u8d75\u7490\u3001\u674e\u5b50\u8587\u548c\u8c2d\u6d9b\uff1b\u4ee5\u53ca\u534e\u5927\u6df1\u5733\u7684\u96f7\u83b9\u3001\u6234\u6eaa\u3001\u5218\u4f20\u5b87\u3001\u9ec4\u5fd7\u6d69\u548c\u5218\u9f99\u5947\u3002.<\/p>\n<p>\u672c\u7814\u7a76\u5f97\u5230\u4e86\u56fd\u5bb6\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\uff082016YFA0101401\uff09\u3001\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\uff0881760271\uff09\u3001\u4e91\u5357\u7701\u91cd\u5927\u79d1\u6280\u4e13\u9879\uff082017ZF028\uff09\u4ee5\u53ca\u4e91\u5357\u7701\u57fa\u7840\u7814\u7a76\u91cd\u70b9\u9879\u76ee\uff082017FA010\uff09\u7684\u8d44\u52a9\u3002Juan Carlos Izpisua Belmonte\u5b9e\u9a8c\u5ba4\u7684\u5de5\u4f5c\u5f97\u5230\u4e86The Moxie Foundation\u7684\u652f\u6301\u3002.<\/p>","protected":false},"featured_media":24746,"template":"","faculty":[85],"disease-research":[146],"class_list":["post-24736","disclosure","type-disclosure","status-publish","has-post-thumbnail","hentry","faculty-juan-carlos-izpisua-belmonte","disease-research-aging-and-regenerative-medicine"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Unlocking the black box of embryonic development - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/zh\/news-release\/unlocking-the-black-box-of-embryonic-development\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" 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