{"id":2443,"date":"2013-07-25T00:00:00","date_gmt":"2013-07-25T07:00:00","guid":{"rendered":"https:\/\/vermont.salk.edu\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/"},"modified":"2013-07-25T00:00:00","modified_gmt":"2013-07-25T07:00:00","slug":"salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury","status":"publish","type":"disclosure","link":"https:\/\/www.salk.edu\/zh\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/","title":{"rendered":"\u7d22\u5c14\u514b\u79d1\u5b66\u5bb6\u53d1\u73b0\u810a\u9ad3\u635f\u4f24\u7684\u65b0\u673a\u5236"},"content":{"rendered":"<p>\u62c9\u970d\u4e9a\uff0c\u52a0\u5229\u798f\u5c3c\u4e9a\u5dde\u2014\u2014\u6bcf\u5e74\u6709\u8d85\u8fc7 11,000 \u540d\u7f8e\u56fd\u4eba\u906d\u53d7\u810a\u9ad3\u635f\u4f24\uff0c\u5176\u4e2d\u8d85\u8fc7\u56db\u5206\u4e4b\u4e00\u7684\u635f\u4f24\u662f\u7531\u4e8e\u8dcc\u5012\u9020\u6210\u7684\uff0c\u968f\u7740\u4eba\u53e3\u8001\u9f84\u5316\uff0c\u8fd9\u4e00\u6570\u5b57\u53ef\u80fd\u4f1a\u4e0a\u5347\u3002\u810a\u9ad3\u635f\u4f24\u4e4b\u6240\u4ee5\u5982\u6b64\u591a\u4e14\u6c38\u4e45\u81f4\u6b8b\uff0c\u662f\u56e0\u4e3a\u4eba\u4f53\u7f3a\u4e4f\u518d\u751f\u795e\u7ecf\u7ea4\u7ef4\u7684\u80fd\u529b\u3002\u6211\u4eec\u8eab\u4f53\u6240\u80fd\u505a\u7684\u6700\u597d\u7684\u5c31\u662f\u5c06\u5e78\u5b58\u7684\u7ec4\u7ec7\u7ed5\u8fc7\u635f\u4f24\u90e8\u4f4d\u3002.\n <\/p>\n<p>\n\u201c\u5c31\u50cf\u5730\u9707\u540e\u7684\u7ed5\u884c\uff0c\u201d\u8bf4 <a href=\"\/zh\/faculty\/lee.html\/\">\u674e\u90ed\u82ac<\/a>, \u7d22\u5c14\u514b\u7814\u7a76\u6240\u5206\u5b50\u795e\u7ecf\u751f\u7269\u5b66\u6d77\u4f26\u00b7\u9ea6\u514b\u6d1b\u6797\u4e3b\u5e2d\u3002\u201c\u5982\u679c\u9ad8\u901f\u516c\u8def\u5835\u585e\u4e86\uff0c\u4f46\u4f60\u4ecd\u7136\u53ef\u4ee5\u8d70\u5c0f\u8def\uff0c\u4ea4\u901a\u4ecd\u7136\u53ef\u4ee5\u7545\u901a\u3002\u6240\u4ee5\u4f60\u7684\u7b56\u7565\u5fc5\u987b\u662f\u5c3d\u53ef\u80fd\u591a\u5730\u4fdd\u5b58\u7ec4\u7ec7\uff0c\u7ed9\u81ea\u5df1\u4e00\u4e2a\u7ebf\u8def\u91cd\u7ed5\u7684\u673a\u4f1a\u3002\u201d\n <\/p>\n<div class=\"imageCaption\"><img decoding=\"async\" alt=\"Kuo-Fen Lee, and Tsung Chang Sung\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2013\/01\/632lee.jpg\"><\/p>\n<p>\n\u4ece\u5de6\u5230\u53f3\uff1a\u7d22\u5c14\u514b\u79d1\u5b66\u5bb6\u674e\u56fd\u82ac\uff08Kuo-Fen Lee\uff09\u548c\u5b8b\u5d07\u660c\uff08Tsung Chang Sung\uff09\u3002.\n<\/p>\n<p>\n\u56fe\u7247\uff1a\u7531\u8428\u514b\u751f\u7269\u7814\u7a76\u6240\u63d0\u4f9b\n<\/p>\n<\/div>\n<p>\n\u5728\u672c\u5468\u53d1\u8868\u7684\u4e00\u7bc7\u8bba\u6587\u4e2d <em><a href=\"http:\/\/www.plosone.org\/article\/info%3Adoi%2F10.1371%2Fjournal.pone.0069286\">PLOS ONE<\/a><\/em>, \u674e\u548c\u4ed6\u7684\u540c\u4e8b\u4eec\u63cf\u8ff0\u4e86\u4e00\u79cd\u540d\u4e3a P45 \u7684\u86cb\u767d\u8d28\u5982\u4f55\u4e3a\u810a\u9ad3\u4fee\u590d\u548c\u529f\u80fd\u6062\u590d\u63d0\u4f9b\u53ef\u80fd\u7684\u5206\u5b50\u673a\u5236\u3002\u7531\u4e8e\u53d7\u4f24\u7684\u5c0f\u9f20\u6bd4\u4eba\u7c7b\u6062\u590d\u5f97\u66f4\u5168\u9762\uff0c\u674e\u4e00\u76f4\u5728\u5bfb\u627e\u5dee\u5f02\u7684\u6839\u6e90\u3002\u4ed6\u53d1\u73b0 P45 \u5177\u6709\u5148\u524d\u672a\u77e5\u7684\u795e\u7ecf\u4fdd\u62a4\u4f5c\u7528\u3002.\n <\/p>\n<p>\n\u201c\u4f5c\u4e3a\u4e00\u540d\u751f\u7269\u5316\u5b66\u5bb6\u548c\u795e\u7ecf\u751f\u7269\u5b66\u5bb6\uff0c\u8fd9\u9879\u53d1\u73b0\u8ba9\u6211\u770b\u5230\u4e86\u5bfb\u627e\u836f\u7269\u7597\u6cd5\u9776\u5206\u5b50\u7684\u5e0c\u671b\uff0c\u201d\u674e\u8bf4\u3002\u201c\u5c3d\u7ba1\u5982\u6b64\uff0c\u6211\u5fc5\u987b\u8b66\u544a\u8bf4\uff0c\u8fd9\u4ec5\u4ec5\u662f\u4e86\u89e3\u5bfb\u627e\u4ec0\u4e48\u7684\u7b2c\u4e00\u6b65\u3002\u201d\n <\/p>\n<p>\n\u5728\u4eba\u7c7b\u6216\u5c0f\u9f20\u4e2d\uff0c\u810a\u9ad3\u635f\u4f24\u540e\u5c1d\u8bd5\u7684\u795e\u7ecf\u91cd\u5851\u80fd\u5426\u6210\u529f\uff0c\u53d6\u51b3\u4e8e\u5269\u4f59\u5065\u5eb7\u7ec4\u7ec7\u7684\u6570\u91cf\u3002\u4f46\u635f\u4f24\u4f1a\u5f15\u53d1\u7ec6\u80de\u5185\u4e00\u7cfb\u5217\u7684\u53cd\u5e94\uff0c\u5982\u679c\u4e0d\u80fd\u53ca\u65f6\u963b\u6b62\uff0c\u5c06\u4f1a\u5bfc\u81f4\u635f\u4f24\u90e8\u4f4d\u4ee5\u5916\u7684\u7ec4\u7ec7\u6b7b\u4ea1\u6216\u574f\u6b7b\u3002\u635f\u4f24\u90e8\u4f4d\u7684\u795e\u7ecf\u7275\u62c9\u4f1a\u5bfc\u81f4\u6b63\u5e38\u611f\u89c9\u548c\u8fd0\u52a8\u529f\u80fd\u6240\u9700\u7684\u7f51\u7edc\u8fde\u63a5\u65ad\u5f00\u3002\u674e\u535a\u58eb\u53d1\u73b0 P45 \u662f\u51b3\u5b9a\u8fd9\u79cd\u7ea7\u8054\u53cd\u5e94\u662f\u5426\u4f1a\u7ee7\u7eed\u5176\u7834\u574f\u6027\u7ed3\u5c40\u7684\u5173\u952e\u56e0\u7d20\u3002.\n <\/p>\n<p>\n\u86cb\u767d\u8d28\u590d\u5408\u7269\u901a\u8fc7\u76f8\u4e92\u4f9d\u6b21\u4f5c\u7528\uff0c\u8bf1\u5bfc\u4e86\u8fd9\u79cd\u7ec6\u80de\u6b7b\u4ea1\u7ea7\u8054\u53cd\u5e94\u3002\u674e\u53d1\u73b0 P45 \u662f\u8be5\u8fc7\u7a0b\u7684\u5929\u7136\u62ee\u6297\u5242\u3002\u62ee\u6297\u5242\u662f\u5206\u5b50\uff0c\u6709\u4e9b\u662f\u5929\u7136\u5b58\u5728\u7684\uff0c\u6709\u4e9b\u662f\u5728\u5236\u836f\u5b9e\u9a8c\u5ba4\u5236\u9020\u7684\uff0c\u5b83\u4eec\u7684\u4f5c\u7528\u539f\u7406\u57fa\u672c\u4e0a\u5c31\u50cf\u5728\u9501\u5b54\u91cc\u585e\u5165\u53e3\u9999\u7cd6\u3002\u56e0\u4e3a\u62ee\u6297\u5242\u5728\u4f4d\uff0c\u5176\u4ed6\u5206\u5b50\u5c31\u65e0\u6cd5\u8fdb\u5165\u3002\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0cP45 \u963b\u6b62\u4e86\u6b7b\u4ea1\u7ea7\u8054\u53cd\u5e94\u4e2d\u7684\u53e6\u5916\u4e24\u79cd\u86cb\u767d\u8d28\u7684\u8fde\u63a5\uff0c\u4f7f\u5176\u4f5c\u7528\u5931\u6548\u5e76\u963b\u6b62\u7ec6\u80de\u6b7b\u4ea1\u3002.\n <\/p>\n<div class=\"imageCaption530\"><img decoding=\"async\" alt=\"massive cell death\" src=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2013\/01\/632.jpg\"><\/p>\n<p>\n\u810a\u9ad3\u635f\u4f24\u4f1a\u5bfc\u81f4\u5927\u91cf\u7684\u7ec6\u80de\u6b7b\u4ea1\uff0c\u7c89\u7ea2\u8272\u7ec6\u80de\u7684\u6570\u91cf\uff08\u5de6\u4fa7\uff09\u5373\u4e3a\u6b64\u4f8b\u8bc1\u3002\u7136\u800c\uff0c\u5f53\u8fd9\u4e9b\u7ec6\u80de\u4e2d p45 \u7684\u6c34\u5e73\u5347\u9ad8\u65f6\uff0c\u8fd9\u4e00\u8fc7\u7a0b\u4f1a\u663e\u8457\u51cf\u5c11\uff08\u53f3\u4fa7\uff09\u3002.\n  <\/p>\n<p>\n\u56fe\u7247\uff1a\u7531\u8428\u514b\u751f\u7269\u7814\u7a76\u6240\u63d0\u4f9b\n<\/p>\n<\/div>\n<p>\n\u4f46 P45 \u7684\u8fd0\u4f5c\u65b9\u5f0f\u8fd8\u6709\u66f4\u591a\u4e4b\u5904\uff0c\u8fd9\u8ba9\u674e\u770b\u5230\u4e86\u4ed6\u53ef\u80fd\u6b63\u671d\u7740\u4e00\u79cd\u72ec\u7279\u7684\u65b9\u6cd5\u6765\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u65b0\u9014\u5f84\u3002\u5728\u4ed6\u7684\u56e2\u961f\u8fd1\u671f\u5373\u5c06\u53d1\u8868\u7684\u7814\u7a76\u4e2d\uff0c\u4ed6\u4eec\u8fd8\u53d1\u73b0 P45 \u4e5f\u80fd\u4ea7\u751f\u79ef\u6781\u6548\u5e94\uff0c\u7279\u522b\u662f\u4fc3\u8fdb\u5065\u5eb7\u7ec4\u7ec7\u7684\u751f\u957f\u3002\u56e0\u6b64\uff0c\u674e\u65ad\u5b9a P45 \u7684\u771f\u6b63\u4f5c\u7528\u53ef\u80fd\u662f\u4e00\u79cd\u201c\u8df7\u8df7\u677f\u201d\u5206\u5b50\uff0c\u80fd\u591f\u5c06\u7ea7\u8054\u53cd\u5e94\u4ece\u8d1f\u9762\u5bfc\u5411\u6b63\u9762\u3002.\n <\/p>\n<p>\n\u201cP45 \u7684\u4f1f\u5927\u4e4b\u5904\u5728\u4e8e\uff0c\u5b83\u65e2\u80fd\u901a\u8fc7\u963b\u65ad\u53ef\u80fd\u5bfc\u81f4\u66f4\u591a\u7ec6\u80de\u6b7b\u4ea1\u7684\u6784\u8c61\u53d8\u5316\u6765\u6291\u5236\u8d1f\u9762\u5f71\u54cd\uff0c\u53c8\u80fd\u4fc3\u8fdb\u6b63\u9762\u6548\u5e94\u2014\u2014\u7ec4\u7ec7\u7684\u5b58\u6d3b\u548c\u751f\u957f\uff0c\u4ece\u800c\u66f4\u5bb9\u6613\u4fc3\u8fdb\u810a\u9ad3\u635f\u4f24\u540e\u7684\u6062\u590d\uff0c\u201d\u674e\u89e3\u91ca\u9053\u3002.\n <\/p>\n<p>\n\u201c\u5982\u679c\u4f60\u80fd\u7406\u89e3\u5982\u4f55\u626d\u8f6c\u5e73\u8861\uff0c\u4f7f\u5176\u503e\u5411\u4e8e\u6b63\u9762\u6216\u8d1f\u9762\u4fe1\u53f7\uff0c\u5c31\u80fd\u51cf\u5c11\u635f\u4f24\uff0c\u540c\u65f6\u4fc3\u8fdb\u6108\u5408\uff0c\u201d\u674e\u8bf4\u3002\u201c\u8fd9\u53ef\u80fd\u662f\u7ec4\u5408\u5f0f\u7684\u2014\u2014\u4e5f\u8bb8\u4e00\u4e2a\u5206\u5b50\u5c31\u80fd\u505a\u5230\u8fd9\u4e24\u70b9\uff0c\u6216\u8005\u53ef\u80fd\u662f\u4e24\u4e2a\u5206\u5b50\u7684\u7ec4\u5408\uff0c\u4e00\u4e2a\u7528\u6765\u62b5\u6d88\uff0c\u4e00\u4e2a\u7528\u6765\u4fc3\u8fdb\u3002\u5e0c\u671b\u662f\uff0c\u5982\u679c\u80fd\u627e\u5230\u8fd9\u6837\u7684\u63a7\u5236\u5f00\u5173\uff0c\u5c31\u53ef\u4ee5\u5728\u635f\u4f24\u90e8\u4f4d\u4fdd\u7559\u66f4\u591a\u7684\u7ec4\u7ec7\uff0c\u4ece\u800c\u589e\u52a0\u6709\u4e00\u5929\u6062\u590d\u8fd0\u52a8\u7684\u673a\u4f1a\u3002\u201d\n <\/p>\n<p>\n\u674e\u5b9e\u9a8c\u5ba4\u7684\u4e0b\u4e00\u6b65\u5c06\u662f\u5bfb\u627e\u4e00\u79cd\u57fa\u56e0\uff0c\u6216\u8005\u4e00\u79cd\u5728\u4eba\u4f53\u4e2d\u4ee5\u7c7b\u4f3c\u8df7\u8df7\u677f\u65b9\u5f0f\u5de5\u4f5c\u7684\u8fc7\u7a0b\uff0c\u6216\u8005\u53ef\u4ee5\u901a\u8fc7\u6cbb\u7597\u5e72\u9884\u4f7f\u5176\u8d77\u4f5c\u7528\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c\u674e\u8b66\u544a\u8bf4\uff0c\u8fd9\u4ecd\u7136\u662f\u5c0f\u9f20\u7684\u539f\u7406\u9a8c\u8bc1\u5b9e\u9a8c\u3002\u5373\u4f7f\u5728\u4eba\u4f53\u4e2d\u53d1\u73b0\u4e86\u8fd9\u6837\u7684\u673a\u5236\uff0c\u4e34\u5e8a\u5e94\u7528\u4e5f\u8fd8\u9700\u8981\u6570\u5e74\u65f6\u95f4\u3002.\n <\/p>\n<p>\n\u8be5\u7814\u7a76\u7684\u5176\u4ed6\u7814\u7a76\u4eba\u5458\u5305\u62ec\u5b8b\u5b97\u660c\uff08Tsung-Chang Sung\uff09\u3001\u9648\u5fd7\u6c5f\uff08Zhijiang Chen\uff09\u3001\u6851\u5fb7\u7433\u00b7\u56fe\u96f7\u7279\uff08Sandrine Thuret\uff09\u3001\u9a6c\u8d5b\u5c14\u00b7\u7ef4\u62c9\u5c14\uff08Mar\u00e7al Vilar\uff09\uff0c, <a href=\"\/zh\/faculty\/gage.html\/\">\u5f17\u96f7\u5fb7\u00b7H\u00b7\u76d6\u5947<\/a> \u4ee5\u53ca\u7d22\u5c14\u514b\u7814\u7a76\u6240\u7684 Roland Riek\u3002.\n <\/p>\n<p>\n\u672c\u5de5\u4f5c\u5f97\u5230\u4e86...\u7684\u652f\u6301 <a href=\"http:\/\/www.nih.gov\/\">\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662<\/a>, <a href=\"http:\/\/www.nia.nih.gov\/\">\u56fd\u5bb6\u8870\u8001\u7814\u7a76\u6240<\/a>, <a href=\"http:\/\/mda.org\/\">MDA<\/a>, \u514b\u83b1\u987f\u57fa\u91d1\u4f1a, <a href=\"http:\/\/www.pva.org\/site\/c.ajIRK9NJLcJ2E\/b.6305827\/k.7268\/PVA_Research_Foundation.htm\">\u7f8e\u56fd\u762b\u75ea\u9000\u4f0d\u519b\u4eba\u810a\u9ad3\u635f\u4f24\u7814\u7a76\u57fa\u91d1\u4f1a<\/a>, \u7f8e\u56fd\u762b\u75ea\u9879\u76ee, <a href=\"http:\/\/www.christopherreeve.org\/site\/c.ddJFKRNoFiG\/b.4048063\/k.C5D5\/Christopher_Reeve_Spinal_Cord_Injury_and_Paralysis_Foundation.htm\">\u514b\u91cc\u65af\u6258\u5f17\u548c\u8fbe\u7eb3\u00b7\u91cc\u592b\u57fa\u91d1\u4f1a<\/a>, <a href=\"http:\/\/www.mineco.gob.es\/portal\/site\/mineco\/\">\u7ecf\u6d4e\u548c\u7ade\u4e89\u529b\u90e8<\/a> \u548c <a href=\"http:\/\/www.isciii.es\/\">\u5361\u6d1b\u65af\u4e09\u4e16\u5065\u5eb7\u7814\u7a76\u6240<\/a>.\n<\/p>\n<p><strong><br \/>\n\u5173\u4e8e\u7d22\u5c14\u514b\u751f\u7269\u7814\u7a76\u6240\uff1a<\/strong><br \/>\n\u7d22\u5c14\u514b\u751f\u7269\u7814\u7a76\u6240\u662f\u4e16\u754c\u9876\u5c16\u7684\u57fa\u7840\u7814\u7a76\u673a\u6784\u4e4b\u4e00\uff0c\u5176\u56fd\u9645\u77e5\u540d\u7684\u6559\u804c\u4eba\u5458\u5728\u4e00\u4e2a\u72ec\u7279\u3001\u534f\u4f5c\u548c\u5bcc\u6709\u521b\u9020\u6027\u7684\u73af\u5883\u4e2d\uff0c\u6df1\u5165\u63a2\u7a76\u751f\u547d\u79d1\u5b66\u7684\u57fa\u672c\u95ee\u9898\u3002\u7d22\u5c14\u514b\u79d1\u5b66\u5bb6\u4eec\u81f4\u529b\u4e8e\u53d1\u73b0\u548c\u6307\u5bfc\u672a\u6765\u51e0\u4ee3\u7814\u7a76\u4eba\u5458\uff0c\u901a\u8fc7\u7814\u7a76\u795e\u7ecf\u79d1\u5b66\u3001\u9057\u4f20\u5b66\u3001\u7ec6\u80de\u548c\u690d\u7269\u751f\u7269\u5b66\u4ee5\u53ca\u76f8\u5173\u5b66\u79d1\uff0c\u5728\u764c\u75c7\u3001\u8870\u8001\u3001\u963f\u5c14\u8328\u6d77\u9ed8\u6c0f\u75c7\u3001\u7cd6\u5c3f\u75c5\u548c\u4f20\u67d3\u75c5\u7684\u8ba4\u8bc6\u65b9\u9762\u505a\u51fa\u4e86\u5f00\u521b\u6027\u7684\u8d21\u732e\u3002.\n<\/p>\n<p>\n\u5b66\u9662\u53d6\u5f97\u4e86\u8bb8\u591a\u6210\u5c31\uff0c\u83b7\u5f97\u4e86\u5305\u62ec\u8bfa\u8d1d\u5c14\u5956\u548c\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u9662\u58eb\u5728\u5185\u7684\u65e0\u6570\u8363\u8a89\u3002\u8be5\u7814\u7a76\u6240\u7531\u810a\u9ad3\u7070\u8d28\u708e\u75ab\u82d7\u5148\u9a71 Jonas Salk \u535a\u58eb\u4e8e 1960 \u5e74\u521b\u7acb\uff0c\u662f\u4e00\u5bb6\u72ec\u7acb\u7684\u975e\u8425\u5229\u7ec4\u7ec7\u548c\u5efa\u7b51\u5730\u6807\u3002.<\/p>","protected":false},"featured_media":0,"template":"","faculty":[95],"disease-research":[124,160],"class_list":["post-2443","disclosure","type-disclosure","status-publish","hentry","faculty-kuo-fen-lee","disease-research-neuroscience-and-neurological-disorders","disease-research-spinal-cord-injury"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Salk scientist discovers novel mechanism in spinal cord injury - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/zh\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Salk scientist discovers novel mechanism in spinal cord injury - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"LA JOLLA, CA\u2014More than 11,000 Americans suffer spinal cord injuries each year, and since over a quarter of those injuries are due to falls, the number is likely to rise as the population ages. The reason so many of those injuries are permanently disabling is that the human body lacks the capacity to regenerate nerve fibers. The best our bodies can do is route the surviving tissue around the injury site.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.salk.edu\/zh\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/\" \/>\n<meta property=\"og:site_name\" content=\"Salk Institute for Biological Studies\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk-institute-preview-image.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"628\" \/>\n\t<meta property=\"og:image:height\" content=\"329\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\\\/\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\\\/\",\"name\":\"Salk scientist discovers novel mechanism in spinal cord injury - Salk Institute for Biological Studies\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2013\\\/01\\\/632lee.jpg\",\"datePublished\":\"2013-07-25T07:00:00+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\\\/#breadcrumb\"},\"inLanguage\":\"zh-CN\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-CN\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2013\\\/01\\\/632lee.jpg\",\"contentUrl\":\"https:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2013\\\/01\\\/632lee.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.salk.edu\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Salk scientist discovers novel mechanism in spinal cord injury\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"name\":\"Salk Institute for Biological Studies\",\"description\":\"The Power of Science\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.salk.edu\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"zh-CN\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\",\"name\":\"Salk Institute for Biological Studies\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-CN\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"contentUrl\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"width\":696,\"height\":696,\"caption\":\"Salk Institute for Biological Studies\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Salk scientist discovers novel mechanism in spinal cord injury - Salk Institute for Biological Studies","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.salk.edu\/zh\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/","og_locale":"zh_CN","og_type":"article","og_title":"Salk scientist discovers novel mechanism in spinal cord injury - Salk Institute for Biological Studies","og_description":"LA JOLLA, CA\u2014More than 11,000 Americans suffer spinal cord injuries each year, and since over a quarter of those injuries are due to falls, the number is likely to rise as the population ages. The reason so many of those injuries are permanently disabling is that the human body lacks the capacity to regenerate nerve fibers. The best our bodies can do is route the surviving tissue around the injury site.","og_url":"https:\/\/www.salk.edu\/zh\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/","og_site_name":"Salk Institute for Biological Studies","og_image":[{"width":628,"height":329,"url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk-institute-preview-image.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/","url":"https:\/\/www.salk.edu\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/","name":"Salk scientist discovers novel mechanism in spinal cord injury - Salk Institute for Biological Studies","isPartOf":{"@id":"https:\/\/www.salk.edu\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/#primaryimage"},"image":{"@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/#primaryimage"},"thumbnailUrl":"https:\/\/www.salk.edu\/wp-content\/uploads\/2013\/01\/632lee.jpg","datePublished":"2013-07-25T07:00:00+00:00","breadcrumb":{"@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/#breadcrumb"},"inLanguage":"zh-CN","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.salk.edu\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/"]}]},{"@type":"ImageObject","inLanguage":"zh-CN","@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/#primaryimage","url":"https:\/\/www.salk.edu\/wp-content\/uploads\/2013\/01\/632lee.jpg","contentUrl":"https:\/\/www.salk.edu\/wp-content\/uploads\/2013\/01\/632lee.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/www.salk.edu\/news-release\/salk-scientist-discovers-novel-mechanism-in-spinal-cord-injury\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.salk.edu\/"},{"@type":"ListItem","position":2,"name":"Salk scientist discovers novel mechanism in spinal cord injury"}]},{"@type":"WebSite","@id":"https:\/\/www.salk.edu\/#website","url":"https:\/\/www.salk.edu\/","name":"\u7d22\u5c14\u514b\u751f\u7269\u7814\u7a76\u6240","description":"\u79d1\u5b66\u7684\u529b\u91cf","publisher":{"@id":"https:\/\/www.salk.edu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.salk.edu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"zh-CN"},{"@type":"Organization","@id":"https:\/\/www.salk.edu\/#organization","name":"\u7d22\u5c14\u514b\u751f\u7269\u7814\u7a76\u6240","url":"https:\/\/www.salk.edu\/","logo":{"@type":"ImageObject","inLanguage":"zh-CN","@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/","url":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","contentUrl":"http:\/\/www.salk.edu\/wp-content\/uploads\/2023\/03\/salk_logo_696.jpg","width":696,"height":696,"caption":"Salk Institute for Biological Studies"},"image":{"@id":"https:\/\/www.salk.edu\/#\/schema\/logo\/image\/"}}]}},"ACF":{"paper_url":"http:\/\/www.plosone.org\/article\/info%3Adoi%2F10.1371%2Fjournal.pone.0069286","journal_title":"PLOS one","paper_author_list":"Tsung-Chang Sung, Zhijiang Chen, Sandrine Thuret, Mar&ccedil;al Vilar, Fred H. Gage, Roland Riek, and Kuo-Fen Lee of the Salk Institute","paper_title":"P45 Forms a Complex with FADD and Promotes Neuronal Cell Survival Following Spinal Cord Injury","subhead":"&quot;See-saw&quot; molecule may offer clues to potential therapies in the long-term","home_photo":"632.jpg","listing_photo":"632.jpg","line_2":"&quot;See-saw&quot; molecule may offer clues to potential therapies in the long-term","line_1":"Salk scientist discovers novel mechanism in spinal cord injury"},"_links":{"self":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/disclosure\/2443","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/disclosure"}],"about":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/types\/disclosure"}],"version-history":[{"count":0,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/disclosure\/2443\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/media?parent=2443"}],"wp:term":[{"taxonomy":"faculty","embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/faculty?post=2443"},{"taxonomy":"disease-research","embeddable":true,"href":"https:\/\/www.salk.edu\/zh\/wp-json\/wp\/v2\/disease-research?post=2443"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}