\u4e54\u5b89\u59ae\u00b7\u4e54\u5229\u535a\u58eb.<\/a>, \u690d\u7269\u751f\u7269\u5b66\u5b9e\u9a8c\u5ba4\u6559\u6388\u517c\u4e3b\u4efb\uff0c\u970d\u534e\u5fb7\u00b7\u4f11\u65af\u533b\u5b66\u7814\u7a76\u6240\u7814\u7a76\u5458\u3002. <\/p>\n\u8be5\u7814\u7a76\u7684\u57fa\u7840\u53ef\u80fd\u4e3a\u5176\u4ed6\u751f\u7269\u5b66\u7814\u7a76\u9886\u57df\u63d0\u4f9b\u89c1\u89e3\u3002\u4f8b\u5982\uff0c\u7ec6\u80de\u5668\u4e4b\u95f4\u4e0d\u53d7\u963b\u788d\u7684\u4fe1\u606f\u6d41\u52a8\u7684\u91cd\u8981\u6027\u5df2\u5728\u67d0\u4e9b\u7c7b\u578b\u7684\u764c\u75c7\u4e2d\u5f97\u5230\u8bf4\u660e\uff0c\u5728\u8fd9\u4e9b\u764c\u75c7\u4e2d\uff0c\u7ebf\u7c92\u4f53\u4e0e\u7ec6\u80de\u6838\u4e4b\u95f4\u7684\u901a\u8baf\u4e2d\u65ad\u4f1a\u52a0\u901f\u80bf\u7624\u7684\u8fdb\u5c55\u3002.<\/p>\n
\u53f6\u7eff\u4f53\u4e2d\u7684\u7eff\u8272\u53f6\u7eff\u7d20\u5438\u6536\u5149\u80fd\uff0c\u8fd9\u4e0d\u4ec5\u80fd\u91ca\u653e\u6c27\u6c14\uff0c\u6700\u7ec8\u8fd8\u80fd\u5c06\u7a7a\u6c14\u4e2d\u4f4e\u80fd\u91cf\u7684\u4e8c\u6c27\u5316\u78b3\u8f6c\u5316\u4e3a\u9ad8\u80fd\u91cf\u7684\u5316\u5408\u7269\uff0c\u5982\u8461\u8404\u7cd6\u548c\u6dc0\u7c89\u3002\u53f6\u7eff\u4f53\u662f\u690d\u7269\u7684\u57fa\u672c\u751f\u547d\u7ebf\uff0c\u56e0\u6b64\u7ec6\u80de\u5fc5\u987b\u4e86\u89e3\u5176\u529f\u80fd\u72b6\u6001\u81f3\u5173\u91cd\u8981\u3002.<\/p>\n
\u5728\u65e9\u671f\u7684\u5de5\u4f5c\u4e2d\uff0cChory\u5b9e\u9a8c\u5ba4\u53d1\u73b0\u9006\u884c\u4fe1\u53f7\uff08\u5373\u4ece\u53f6\u7eff\u4f53\u5230\u7ec6\u80de\u6838\u7684\u4fe1\u53f7\uff09\u7684\u4e00\u4e2a\u91cd\u8981\u529f\u80fd\u662f\u534f\u8c03\u53f6\u7eff\u4f53\u4e2d\u5408\u6210\u7684\u5149\u5408\u86cb\u767d\u4e0e\u7ec6\u80de\u6838\u4e2d\u7f16\u7801\u7684\u4e9a\u57fa\u7684\u751f\u7269\u5408\u6210\u3002\u7136\u540e\uff0c\u8fd9\u4e9b\u86cb\u767d\u8d28\u5728\u53f6\u7eff\u4f53\u4e2d\u7ec4\u88c5\u6210\u529f\u80fd\u6027\u590d\u5408\u7269\u3002\u5728\u62df\u5357\u82a5\u690d\u7269\u4e2d\u8fdb\u884c\u7684\u5b9e\u9a8c \u62df\u5357\u82a5<\/em>, \u690d\u7269\u751f\u7269\u5b66\u5bb6\u7684\u201c\u8bd5\u9a8c\u54c1\u201d\uff0c\u4ed6\u4eec\u53d1\u73b0\uff0c\u5f53\u53f6\u7eff\u7d20\u524d\u4f53\u5206\u5b50\u5728\u53f6\u7eff\u4f53\u4e2d\u79ef\u7d2f\u65f6\uff0c\u6570\u767e\u4e2a\u6838\u57fa\u56e0\u4f1a\u88ab\u5173\u95ed\uff0c\u4ee5\u5207\u65ad\u88ab\u5361\u4f4f\u7684\u4f9b\u5e94\u7ebf\u3002\u6291\u5236\u53f6\u7eff\u4f53\u86cb\u767d\u8d28\u5408\u6210\u7684\u9664\u8349\u5242\u4e5f\u4ea7\u751f\u76f8\u540c\u6548\u679c\u3002.<\/p>\n\u5728\u6781\u7aef\u5149\u7167\u6761\u4ef6\u4e0b\uff0c\u4f8b\u5982\u6d3b\u6027\u6c27\u5f00\u59cb\u79ef\u805a\u65f6\uff0c\u690d\u7269\u7ec6\u80de\u4f1a\u4e3b\u52a8\u51cf\u5c0f\u96c6\u5149\u590d\u5408\u4f53\u7684\u5c3a\u5bf8\u4ee5\u7f13\u89e3\u6c27\u5316\u5e94\u6fc0\u3002\u201c\u4e3a\u4e86\u4fdd\u62a4\u53f6\u7eff\u4f53\u514d\u53d7\u8fc7\u5ea6\u5149\u5408\u4f5c\u7528\u526f\u4ea7\u7269\u7684\u6d3b\u6027\u6c27\u5206\u5b50\u7684\u635f\u5bb3\uff0c\u53f6\u7eff\u4f53\u6307\u793a\u7ec6\u80de\u6838\u6682\u65f6\u201d\u51b7\u5374\u2019\u4e00\u4e0b\uff0c\u201dChory\u89e3\u91ca\u8bf4\u3002. <\/p>\n
\u5c3d\u7ba1\u5f88\u660e\u663e\u6240\u6709\u8fd9\u4e9b\u4e0d\u540c\u7684\u4fe1\u53f7\u90fd\u5fc5\u987b\u4f20\u9012\u5230\u7ec6\u80de\u6838\u4ee5\u5f15\u53d1\u4fdd\u62a4\u6027\u53cd\u5e94\uff0c\u4f46\u5c1a\u4e0d\u6e05\u695a\u8fd9\u4e9b\u4fe1\u606f\u662f\u5982\u4f55\u4f20\u9012\u7684\u3002\u4e3a\u4e86\u5f00\u59cb\u586b\u8865\u8fd9\u4e9b\u7a7a\u767d\uff0c\u5171\u540c\u7b2c\u4e00\u4f5c\u8005\u3001\u4e54\u91cc\u5b9e\u9a8c\u5ba4\u524d\u535a\u58eb\u540e\u7814\u7a76\u5458\u3001\u73b0\u4efb\u5370\u5ea6\u6d77\u5f97\u62c9\u5df4\u5148\u950b\u516c\u53f8\u7814\u7a76\u5458 Ajit Nott \u5f00\u59cb\u7814\u7a76 \u62df\u5357\u82a5<\/em> \u57fa\u56e0\u7ec4\u4ee5\u53ca\u5141\u8bb8\u690d\u7269\u5bf9\u53f6\u7eff\u4f53\u635f\u4f24\u505a\u51fa\u53cd\u5e94\u7684\u57fa\u56e0\u3002. <\/p>\n\u4ed6\u7684\u641c\u7d22\u7ed3\u679c\u662fGUN1\uff0c\u8fd9\u662f g<\/u>\u57fa\u56e0\u7ec4 \u8054\u5408\u56fd<\/u>\u8026\u5408<\/em> 1. \u4ed6\u53ef\u4ee5\u5c06\u4e00\u79cd\u6838\u7f16\u7801\u7684\u86cb\u767d\u8d28\u8ffd\u8e2a\u5230\u53f6\u7eff\u4f53\u5185\u7684\u7279\u5b9a\u533a\u57df\u3002\u65e0\u8bba\u53f6\u7eff\u4f53\u627f\u53d7\u4f55\u79cd\u80c1\u8feb\uff0c\u6240\u6709\u4fe1\u53f7\u90fd\u5bfc\u5411GUN1\uff0c\u7136\u540e\u624d\u4f20\u9012\u5230\u7ec6\u80de\u6838\u3002.<\/p>\n\u201c\u786e\u5b9a GUN1 \u7684\u8eab\u4efd\u662f\u4e86\u89e3\u9006\u884c\u4fe1\u53f7\u673a\u5236\u7684\u4e00\u4e2a\u91cd\u8981\u4e14\u671f\u5f85\u5df2\u4e45\u7684\u8fdb\u5c55\uff0c\u201dNott \u8bf4\uff0c\u5e76\u8865\u5145\u8bf4\uff1a\u201c\u591a\u79cd\u9006\u884c\u4fe1\u53f7\u7684\u6c47\u805a\u548c GUN1 \u86cb\u767d\u7684\u6027\u8d28\u4fc3\u4f7f\u6211\u4eec\u4fee\u6b63\u4e86\u5173\u4e8e\u8102\u8d28\u4f53\u5b9e\u9645\u9006\u884c\u4fe1\u53f7\u7684\u5047\u8bbe\u3002\u201d<\/p>\n
\u5171\u540c\u7b2c\u4e00\u4f5c\u8005Shai Koussevitzky\uff0c\u73b0\u4efb\u5185\u534e\u8fbe\u5927\u5b66\u96f7\u8bfa\u5206\u6821\u7684\u7814\u7a76\u52a9\u7406\uff0c\u7814\u7a76\u4e86\u4fe1\u53f7\u901a\u8def\u7684\u672b\u7aef\uff1a\u53d7\u5230\u9006\u884c\u4fe1\u53f7\u5f71\u54cd\u7684\u6838\u57fa\u56e0\u3002\u4ed6\u8bc6\u522b\u51fa\u5927\u591a\u6570\u53d7\u9006\u884c\u4fe1\u53f7\u5f71\u54cd\u7684\u57fa\u56e0\u8c03\u63a7\u533a\u57df\u4e2d\u7684\u4e00\u4e2a\u77ed\u57fa\u5e8f\uff0c\u5e76\u5c06ABI4\u786e\u5b9a\u4e3a\u76f8\u5e94\u7684\u7ed3\u5408\u56e0\u5b50\u3002. <\/p>\n
\u5149\u8bf1\u5bfc\u57fa\u56e0\u901a\u5e38\u5728\u5149\u5408\u4f5c\u7528\u4e2d\u8d77\u6838\u5fc3\u4f5c\u7528\uff0c\u800c\u4e14\u5f80\u5f80\u4f1a\u88ab\u5bfc\u5165\u53f6\u7eff\u4f53\u3002\u201c\u6211\u4eec\u63d0\u51fa ABI4 \u7ed3\u5408\u65b0\u8bc6\u522b\u51fa\u7684\u5e8f\u5217\u57fa\u5e8f\uff0c\u4ece\u800c\u963b\u6b62\u5149\u8bf1\u5bfc\u7684\u8c03\u63a7\u56e0\u5b50\u6fc0\u6d3b\u57fa\u56e0\u8868\u8fbe\uff0c\u201dKoussevitzky \u8bf4\u3002\u201cABI4 \u53ef\u80fd\u662f\u4e4b\u524d\u63d0\u51fa\u7684\u3001\u534f\u8c03\u690d\u7269\u5bf9\u73af\u5883\u80c1\u8feb\u53cd\u5e94\u7684\u2018\u603b\u5f00\u5173\u2019\u3002\u201d<\/p>\n
\u8fd9\u9879\u5de5\u4f5c\u5f97\u5230\u4e86\u970d\u534e\u5fb7\u4f11\u65af\u533b\u5b66\u7814\u7a76\u6240\u548c\u80fd\u6e90\u90e8\u8d60\u6b3e\u7684\u8d44\u52a9\u3002Shai Kousssevitzky\u5f97\u5230\u4e86EMBO\u548c\u970d\u534e\u5fb7\u4f11\u65af\u533b\u5b66\u7814\u7a76\u6240\u7684\u652f\u6301\uff0cAjit Nott\u5f97\u5230\u4e86\u8fbe\u8499\u00b7\u6717\u6069\u764c\u75c7\u57fa\u91d1\u7684\u652f\u6301\u3002.<\/p>\n
\u4f4d\u4e8e\u52a0\u5229\u798f\u5c3c\u4e9a\u5dde\u62c9\u970d\u4e9a\u7684\u8428\u5c14\u514b\u751f\u7269\u7814\u7a76\u6240\u662f\u4e00\u5bb6\u72ec\u7acb\u7684\u975e\u8425\u5229\u7ec4\u7ec7\uff0c\u81f4\u529b\u4e8e\u57fa\u7840\u751f\u547d\u79d1\u5b66\u53d1\u73b0\u3001\u6539\u5584\u4eba\u7c7b\u5065\u5eb7\u4ee5\u53ca\u57f9\u517b\u4e0b\u4e00\u4ee3\u7814\u7a76\u4eba\u5458\u3002\u5176\u810a\u9ad3\u7070\u8d28\u708e\u75ab\u82d7\u57281955\u5e74\u51e0\u4e4e\u6839\u9664\u4e86\u8fd9\u79cd\u81f4\u6b8b\u75be\u75c5\u5c0f\u513f\u9ebb\u75f9\u75c7\u7684\u4e54\u7eb3\u65af\u00b7\u8428\u5c14\u514b\u533b\u5b66\u535a\u58eb\u4e8e1965\u5e74\u5f00\u8bbe\u4e86\u8be5\u7814\u7a76\u6240\uff0c\u8be5\u7814\u7a76\u6240\u5f97\u5230\u4e86\u5723\u5730\u4e9a\u54e5\u5e02\u7684\u571f\u5730\u8d60\u4e0e\u4ee5\u53ca\u201cMarch of Dimes\u201d\u7684\u8d22\u653f\u652f\u6301\u3002. <\/p>","protected":false},"featured_media":0,"template":"","faculty":[83],"disease-research":[],"class_list":["post-1897","disclosure","type-disclosure","status-publish","hentry","faculty-joanne-chory"],"acf":[],"yoast_head":"\n
All roads lead to GUN1 - Salk Institute for Biological Studies<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.salk.edu\/zh\/news-release\/all-roads-lead-to-gun1\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"All roads lead to GUN1 - Salk Institute for Biological Studies\" \/>\n<meta property=\"og:description\" content=\"La Jolla, CA \u2013 Scientists have identified three different signals that indicate damage to chloroplasts \u2013 the photosynthetic factories of plant cells that give plants their green color \u2013 but little is known about how the signal gets passed on to the nucleus. Scientists at the Salk Institute for Biological Studies made a big step towards explaining how chloroplasts let a cell’s nucleus know when things start to go wrong at the periphery so nuclear gene expression can be adjusted accordingly.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.salk.edu\/zh\/news-release\/all-roads-lead-to-gun1\/\" \/>\n<meta property=\"og:site_name\" content=\"Salk Institute for Biological Studies\" \/>\n<meta property=\"article:modified_time\" content=\"2016-01-16T00:46:31+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.salk.eduhttps:\/\/www.salk.edu\/wp-content\/uploads\/2015\/03\/caption_20070329.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/all-roads-lead-to-gun1\\\/\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/all-roads-lead-to-gun1\\\/\",\"name\":\"All roads lead to GUN1 - Salk Institute for Biological Studies\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/all-roads-lead-to-gun1\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/all-roads-lead-to-gun1\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.salk.eduhttps:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2015\\\/03\\\/caption_20070329.jpg\",\"datePublished\":\"2007-03-29T07:00:00+00:00\",\"dateModified\":\"2016-01-16T00:46:31+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/all-roads-lead-to-gun1\\\/#breadcrumb\"},\"inLanguage\":\"zh-CN\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/all-roads-lead-to-gun1\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-CN\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/all-roads-lead-to-gun1\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.salk.eduhttps:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2015\\\/03\\\/caption_20070329.jpg\",\"contentUrl\":\"https:\\\/\\\/www.salk.eduhttps:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2015\\\/03\\\/caption_20070329.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/news-release\\\/all-roads-lead-to-gun1\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.salk.edu\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"All roads lead to GUN1\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#website\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"name\":\"Salk Institute for Biological Studies\",\"description\":\"The Power of Science\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.salk.edu\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"zh-CN\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#organization\",\"name\":\"Salk Institute for Biological Studies\",\"url\":\"https:\\\/\\\/www.salk.edu\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-CN\",\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"contentUrl\":\"http:\\\/\\\/www.salk.edu\\\/wp-content\\\/uploads\\\/2023\\\/03\\\/salk_logo_696.jpg\",\"width\":696,\"height\":696,\"caption\":\"Salk Institute for Biological Studies\"},\"image\":{\"@id\":\"https:\\\/\\\/www.salk.edu\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"All roads lead to GUN1 - Salk Institute for Biological Studies","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.salk.edu\/zh\/news-release\/all-roads-lead-to-gun1\/","og_locale":"zh_CN","og_type":"article","og_title":"All roads lead to GUN1 - Salk Institute for Biological Studies","og_description":"La Jolla, CA \u2013 Scientists have identified three different signals that indicate damage to chloroplasts \u2013 the photosynthetic factories of plant cells that give plants their green color \u2013 but little is known about how the signal gets passed on to the nucleus. 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