\u81ea\u7136<\/em>.<\/p>\n\u4ed6\u5e0c\u671b\u201c\u8fd9\u80fd\u50ac\u751f\u4e00\u7c7b\u65b0\u7684\u80f0\u5c9b\u7d20\u589e\u654f\u836f\u7269\uff0c\u5b83\u4eec\u80fd\u591f\u653e\u677e\u5239\u8f66\uff0c\u8ba9\u80f0\u5c9b\u7d20\u53d1\u6325\u66f4\u957f\u7684\u4f5c\u7528\u3002\u201d<\/p>\n
\u5f53\u80f0\u5c9b\u7d20\u4e0e\u5176\u7ec6\u80de\u8868\u9762\u7684\u53d7\u4f53\u7ed3\u5408\u65f6\uff0c\u5b83\u4f1a\u5f15\u53d1\u4e00\u7cfb\u5217\u7ec6\u80de\u5185\u4fe1\u53f7\uff0c\u4ece\u800c\u4ea7\u751fPIP3\uff0c\u8fd9\u662f\u4e00\u79cd\u7279\u6b8a\u7684\u8102\u8d28\u5206\u5b50\uff0c\u5b83\u6307\u6325\u7740\u4e00\u6574\u5957\u534f\u540c\u4f5c\u7528\u7684\u5206\u5b50\u6765\u5408\u6210\u548c\u50a8\u5b58\u78b3\u6c34\u5316\u5408\u7269\u3001\u8102\u8d28\u548c\u86cb\u767d\u8d28\u3002\u201c\u4f46\u5f00\u542f\u4e00\u4e2a\u751f\u7406\u8fc7\u7a0b\u53ea\u662f\u6545\u4e8b\u7684\u4e00\u534a\uff0c\u201d\u57c3\u6587\u65af\u89e3\u91ca\u8bf4\u3002\u201c\u4f60\u8fd8\u9700\u8981\u6307\u4ee4\u6765\u544a\u8bc9\u7ec6\u80de\u201d\u677e\u5f00\u6cb9\u95e8\uff0c\u8e29\u4e0b\u5239\u8f66\u2019\u3002\u201d<\/p>\n
\u535a\u58eb\u540e\u7814\u7a76\u5458\u3001\u7b2c\u4e00\u4f5c\u8005\u6768\u6653\u52c7\u535a\u58eb\u53d1\u73b0 PIP3 \u540c\u65f6\u8d1f\u8d23\u8fd9\u4e24\u9879\u3002\u4ed6\u7684\u5b9e\u9a8c\u8868\u660e\uff0c\u80f0\u5c9b\u7d20\u4fe1\u53f7\u7f51\u7edc\u7684\u6fc0\u6d3b\u5728\u51e0\u5206\u949f\u5185\u5c31\u4f1a\u4fc3\u4f7f OGT \u4ece\u7ec6\u80de\u6838\u79fb\u51fa\u5e76\u8fdb\u5165\u7ec6\u80de\u8d28\u3002\u5b83\u4f1a\u79fb\u52a8\u5230\u8d28\u819c\u5e76\u4e0e PIP3 \u7ed3\u5408\u3002. <\/p>\n
\u201c\u5b83\u4f7f\u7528\u4e00\u79cd\u65b0\u7684PIP3\u7ed3\u5408\u57df\u6765\u4e0e\u521a\u521a\u6fc0\u6d3b\u7cfb\u7edf\u7684\u76f8\u540c\u8102\u8d28\u76f8\u4e92\u4f5c\u7528\uff0c\u201dXiaoyong\u63cf\u8ff0\u9053\u3002\u201c\u5728OGT\u62db\u52df\u5230\u8d28\u819c\u540e\uff0c\u5b83\u5c31\u5f00\u59cb\u5173\u95ed\u8be5\u7cfb\u7edf\u3002\u201d<\/p>\n
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\u53c2\u4e0e\u8be5\u7814\u7a76\u7684**\u7814\u7a76\u4eba\u5458**\u5305\u62ec\uff1aJoyce C. Havstad\uff08Evans\u5b9e\u9a8c\u5ba4\uff09\u3001Pat P. Ongusaha\uff08\u9a6c\u8428\u8bf8\u585e\u5dde\u603b\u533b\u9662\u548c\u54c8\u4f5b\u533b\u5b66\u9662\uff0c\u67e5\u5c14\u65af\u987f\uff0c\u9a6c\u8428\u8bf8\u585e\u5dde\uff09\u3001Philip D. Miles\u3001Seth J. Field \u548c Jerrold M. Olefsky\uff08\u52a0\u5dde\u5927\u5b66\u5723\u8fed\u6208\u5206\u6821\uff09\u3001Jeffrey E. Kudlow \u548c Fengxue Zhang\uff08\u4e9a\u62c9\u5df4\u9a6c\u5927\u5b66\u4f2f\u660e\u7ff0\u5206\u6821\uff09\u3001W. Venus So\uff08\u7f57\u6c0f\u516c\u53f8\uff0c\u65b0\u6cfd\u897f\u5dde\u7ebd\u74e6\u514b\uff09\u4ee5\u53ca Robert H. Michell\uff08\u4f2f\u660e\u7ff0\u5927\u5b66\uff0c\u82f1\u56fd\u4f2f\u660e\u7ff0\uff09\u3002.<\/p>\n
\u52a0\u5229\u798f\u5c3c\u4e9a\u5dde\u62c9\u970d\u4e9a\u7684\u7d22\u5c14\u514b\u751f\u7269\u5b66\u7814\u7a76\u6240\uff08Salk Institute for Biological Studies\uff09\u662f\u4e00\u4e2a\u72ec\u7acb\u7684\u975e\u8425\u5229\u7ec4\u7ec7\uff0c\u81f4\u529b\u4e8e\u5728\u751f\u547d\u79d1\u5b66\u9886\u57df\u505a\u51fa\u57fa\u7840\u6027\u53d1\u73b0\uff0c\u6539\u5584\u4eba\u7c7b\u5065\u5eb7\uff0c\u5e76\u57f9\u517b\u672a\u6765\u7684\u7814\u7a76\u4eba\u5458\u3002\u5176\u810a\u9ad3\u7070\u8d28\u708e\u75ab\u82d7\u51e0\u4e4e\u6839\u9664\u4e861955\u5e74\u4ee4\u4eba\u8870\u5f31\u7684\u810a\u9ad3\u7070\u8d28\u708e\u75be\u75c5\u7684\u4e54\u7eb3\u65af\u00b7\u7d22\u5c14\u514b\u533b\u5b66\u535a\u58eb\u4e8e1965\u5e74\u521b\u7acb\u4e86\u8be5\u7814\u7a76\u6240\uff0c\u5f97\u5230\u4e86\u5723\u5730\u4e9a\u54e5\u5e02\u8d60\u9001\u7684\u571f\u5730\u4ee5\u53ca\u201cMarch of Dimes\u201d\u7ec4\u7ec7\u7684\u8d22\u653f\u652f\u6301\u3002.<\/p>","protected":false},"featured_media":0,"template":"","faculty":[91],"disease-research":[],"class_list":["post-1851","disclosure","type-disclosure","status-publish","hentry","faculty-ronald-evans"],"acf":[],"yoast_head":"\n
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